Gene

KWMTBOMO07756

Pre Gene Modal

BGIBMGA000891

Annotation

ionotropic_GABA_receptor_subunit_[Bombyx_mori]

Location

Bomo_Chr13(+):6298956-6310099      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.39

CDS

ATGTTGACATCCCATGACGAAGCTACGCCGCGGCACACTCCAAAGATTTTGTCTGCGGCGAAAAACACGTCACGAGATACCGCAGAACCCGACTACTGGGACAACATAAATGAAATAATGTTTTCCAATTACGCCAACTCTAGTTTTGAACAGACAGACGTGTTTACGTGGAAACAGAACAAGAGAAGTATAAACGATGCCGTCTCTAAAAATATAACTTCTGTTTTGGAGAACCTTTTGAAGAACTATGAAAATTCTCAGTTGCCAACGCATGGTAAAGGTTATCCAACTGTAGTTCAAACCAACATCCTAATAAGGAGCATGGGACCAGTTTCAGAACTCGATATGGATTATTCGATGGATTGCTACTTCAGGCAATATTGGCGTGACACGAGGCTGTCGTTTCTCGGTCCCATCCGCTCTTTGTCCCTTTCCATCAAGATGCTCGAGAGGATTTGGAGGCCAGACACGTATTTTTACAACGGAAAACATTCCTATGTACACACTATCACTGTACCGAATAAACTGCTTCGCATCAGTCAACACGGTGATATTTTGTATTCAATGAGATTAACTATTAAAGCTAAATGCCCTATGGAACTTCGTAATTTTCCGATGGATCGTCAATCGTGCCCTCTTATCCTTGGCAGCTACGCCTACTCGAATCAACAACTAGTTTATCAATGGCAAAACTCGCAGAGCGTCAACTTTGTTCCCGGAATGACCCTCTCACAGTTTGACCTTATCAGTTTTCCGTACAGAAATTTCACATTTACCAGACGAGAAGGTGATTTTTCAGTGTTACAAGTCTCTTTCAACCTCAAAAGGCACACCGGCTATTTTCTTATTCAAGTGTACGTGCCCTGCATCCTTATAGTAGTCCTTTCTTGGGTCTCGTTCTGGATTCATCGCGAGGCTACATCCGATCGCGTGGGCTTAGGTATTACCACTGTGCTAACTCTGTCCACGATAAGTCTTGATTCTCGTACCGATTTGCCTAAAGTTCGCTACGCAACCGCACTGGATTGGTTCTTGCTAATGAGTTTCTTTTACTGCATCGCAACTCTACTAGAATTCGCTGGAGTGCATTATTTCACGAAGGTCGGTTCTGGTGAAATAGTTATCGACGATTCGGAATGGGAAGAGCTGATCGAAGAAGTCGGAGGGGACGCGGTCGCGGCACGTGAACTCGCCGTACGTCGTCGTAGTTCTGCTAGATCCGCCACTAATAACCTCTCCATGCCATCCCAAAGTTCAAACCCAACGACTTCGGATAACTTGGAAACTGAACAGCCAGTTGCAGTCCGCCTCACCATGGAACGTACAACTCAGACCGAGACCAGAGTGCCTCGTTGGAGACAACTCTTGTACTGCTTAGCTGGCGACGATCGCTACAGACGACAGAGACAACGGGAAGCAGGGAGTAGGGGACACATCAACAGCGTCTCACACATCGACAGGGCTGCACGTGTTTTATTCCCGGCTTCGTTTGCACTGCTCAATCTATTCTACTGGATGATATATGCCTTCTCGAGTGATGACTTTGCCTGGAGCGACAATCCCATTAATACCTTATCGCATTGA

Protein

MLTSHDEATPRHTPKILSAAKNTSRDTAEPDYWDNINEIMFSNYANSSFEQTDVFTWKQNKRSINDAVSKNITSVLENLLKNYENSQLPTHGKGYPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDTRLSFLGPIRSLSLSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQHGDILYSMRLTIKAKCPMELRNFPMDRQSCPLILGSYAYSNQQLVYQWQNSQSVNFVPGMTLSQFDLISFPYRNFTFTRREGDFSVLQVSFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVGLGITTVLTLSTISLDSRTDLPKVRYATALDWFLLMSFFYCIATLLEFAGVHYFTKVGSGEIVIDDSEWEELIEEVGGDAVAARELAVRRRSSARSATNNLSMPSQSSNPTTSDNLETEQPVAVRLTMERTTQTETRVPRWRQLLYCLAGDDRYRRQRQREAGSRGHINSVSHIDRAARVLFPASFALLNLFYWMIYAFSSDDFAWSDNPINTLSH

Similarity

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

A0A0U4VGB7   E0X9H5   A0A2W1BKQ8   A0A2A4J4D2   A0A194RSQ9   A0A194PDV1   + More
A0A3G1J4Z0   H9IUG1   A0A2H1VYI0   D2A157   A8DMV0   A0A1Y1MAX8   A0A139WJI2   A0A195C9D5   A0A067RK81   A0A158NC41   A0A154PBZ7   A0A195FL08   A0A0C9QIW0   E1ZY67   A0A2J7RFP2   E9J9I1   A0A3L8DWG4   A0A1C9HM80   A0A026VY51   A0A0L7R7A6   A0A182V204   A0A182HIT2   A0A182X2D2   A0A182TTZ4   A0A182TAD2   A0A182M2G4   A0A182XYF7   A0A182IXG1   A0A182N0V1   A0A182VVK4   A0A084VA97   A0NCM7   A0A182R202   A0A182QI39   A0A146MBU7   W5JRF7   N6UNK1   A0A336LLT9   Q0GQQ6   A0A182FK43   A0A232FFQ0   B4L420   A0A0L7L8T8   B4JLF8   B5DSR3   A0A1B0GIH3   B4NPE7   B4M3E7   A0A3Q0JAE5   A0A1B0DRB5   A0A3Q0JAF5   Q9VXL9   B3NXH5   B4PX93   A0A1A9YM90   A0A1A9VSX5   E1JJA9   U4UPN7   A0A1I8MM43   A0A1W4V2W7   A0A1B0BT40   B4IKF9   A0A182PNS5   A0A1J1IXM4   A0A0L0BLK0   A0A0M8ZRL4   A0A1B0G1E6   A0A1A9WIN9   B4HCI5   A0A182K9S2   A0A226E691   N6UNC3   N6TVP1   A0A088A2R6   A0A1B0A1T7   A0A212FHY0   R9S1I4   Q4V4W7   R7UPT2  

Pubmed

20924418    28756777    26354079    19121390    18362917    19820115    + More
17880682    28004739    24845553    21347285    20798317    21282665    30249741    24508170    25244985    24438588    12364791    26823975    20920257    23761445    23537049    16902773    28648823    17994087    26227816    15632085    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    25315136    26108605    22118469    23254933   

EMBL

AB278157    BAT57342.1    GQ890659    ADM88004.1    KZ149987    PZC75662.1    + More
NWSH01003070    PCG67007.1    KQ459700    KPJ20385.1    KQ459606    KPI91198.1    KX856967    ASY91959.1    BABH01001068    ODYU01004917    SOQ45284.1    KQ971338    EFA02907.2    EF545127    ABU63605.1    GEZM01038969    JAV81465.1    KYB28119.1    KQ978068    KYM97474.1    KK852422    KDR24266.1    ADTU01011491    ADTU01011492    ADTU01011493    KQ434869    KZC09372.1    KQ981491    KYN41031.1    GBYB01014668    JAG84435.1    GL435171    EFN73916.1    NEVH01004410    PNF39640.1    GL769313    EFZ10522.1    QOIP01000004    RLU24118.1    KX355314    AOO87784.1    KK107785    EZA47794.1    KQ414642    KOC66724.1    APCN01004087    AXCM01014059    AXCP01007153    ATLV01003051    KE524109    KFB34891.1    AAAB01008846    EAU77351.2    AXCN02001228    GDHC01002117    JAQ16512.1    ADMH02000632    ETN65490.1    APGK01004349    KB735711    ENN83325.1    UFQT01000005    SSX17327.1    DQ667193    ABG75745.1    NNAY01000335    OXU29127.1    CH933810    EDW07298.1    JTDY01002176    KOB71948.1    CH916370    EDW00411.1    CH475585    EDY70824.2    AJWK01014118    CH964291    EDW86387.2    CH940651    EDW65322.2    AJVK01019838    AE014298    BT022901    AAF48539.4    AAY55317.1    CH954180    EDV46934.2    CM000162    EDX01856.2    ACZ95305.1    KB632308    ERL91985.1    JXJN01019977    CH480852    EDW51551.1    CVRI01000063    CRL04832.1    JRES01001701    KNC20828.1    KQ435951    KOX68119.1    CCAG010015963    CH479336    EDW26951.1    LNIX01000006    OXA53155.1    APGK01005252    KB736144    ENN83250.1    APGK01016425    APGK01016426    KB739845    ENN82103.1    AGBW02008449    OWR53344.1    KC710947    AGN03795.1    BT022889    AAY55305.1    AMQN01006847    KB299334    ELU08088.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000005204    UP000007266    UP000078542    + More
UP000027135    UP000005205    UP000076502    UP000078541    UP000000311    UP000235965    UP000279307    UP000053097    UP000053825    UP000075903    UP000075840    UP000076407    UP000075902    UP000075901    UP000075883    UP000076408    UP000075880    UP000075884    UP000075920    UP000030765    UP000007062    UP000075900    UP000075886    UP000000673    UP000019118    UP000069272    UP000215335    UP000009192    UP000037510    UP000001070    UP000001819    UP000092461    UP000007798    UP000008792    UP000079169    UP000092462    UP000000803    UP000008711    UP000002282    UP000092443    UP000078200    UP000030742    UP000095301    UP000192221    UP000092460    UP000001292    UP000075885    UP000183832    UP000037069    UP000053105    UP000092444    UP000091820    UP000008744    UP000075881    UP000198287    UP000005203    UP000092445    UP000007151    UP000014760   

PRIDE

E0X9H5    H9IUG1    Q9VXL9    Q4V4W7   

Pfam

PF02932   Neur_chan_memb        + More
PF02931   Neur_chan_LBD

Interpro

IPR036734   Neur_chan_lig-bd_sf        + More
IPR006202   Neur_chan_lig-bd       
IPR006028   GABAA/Glycine_rcpt       
IPR006029   Neurotrans-gated_channel_TM       
IPR036719   Neuro-gated_channel_TM_sf       
IPR001390   GABAAa_rcpt       
IPR018000   Neurotransmitter_ion_chnl_CS       
IPR006201   Neur_channel       

SUPFAM

SSF63712   SSF63712        + More
SSF90112   SSF90112       

Gene 3D

2.70.170.10    

ProteinModelPortal

A0A0U4VGB7   E0X9H5   A0A2W1BKQ8   A0A2A4J4D2   A0A194RSQ9   A0A194PDV1   + More
A0A3G1J4Z0   H9IUG1   A0A2H1VYI0   D2A157   A8DMV0   A0A1Y1MAX8   A0A139WJI2   A0A195C9D5   A0A067RK81   A0A158NC41   A0A154PBZ7   A0A195FL08   A0A0C9QIW0   E1ZY67   A0A2J7RFP2   E9J9I1   A0A3L8DWG4   A0A1C9HM80   A0A026VY51   A0A0L7R7A6   A0A182V204   A0A182HIT2   A0A182X2D2   A0A182TTZ4   A0A182TAD2   A0A182M2G4   A0A182XYF7   A0A182IXG1   A0A182N0V1   A0A182VVK4   A0A084VA97   A0NCM7   A0A182R202   A0A182QI39   A0A146MBU7   W5JRF7   N6UNK1   A0A336LLT9   Q0GQQ6   A0A182FK43   A0A232FFQ0   B4L420   A0A0L7L8T8   B4JLF8   B5DSR3   A0A1B0GIH3   B4NPE7   B4M3E7   A0A3Q0JAE5   A0A1B0DRB5   A0A3Q0JAF5   Q9VXL9   B3NXH5   B4PX93   A0A1A9YM90   A0A1A9VSX5   E1JJA9   U4UPN7   A0A1I8MM43   A0A1W4V2W7   A0A1B0BT40   B4IKF9   A0A182PNS5   A0A1J1IXM4   A0A0L0BLK0   A0A0M8ZRL4   A0A1B0G1E6   A0A1A9WIN9   B4HCI5   A0A182K9S2   A0A226E691   N6UNC3   N6TVP1   A0A088A2R6   A0A1B0A1T7   A0A212FHY0   R9S1I4   Q4V4W7   R7UPT2  

PDB

6HUG     E-value=8.09788e-78,     Score=740

KEGG

100500931    K05175 gamma-aminobutyric acid receptor subunit alpha | (RefSeq) ionotropic GABA-aminobutyric acid r

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0005230   GO:0004890   GO:0005886   GO:0006811   GO:0004888   GO:0043005   GO:0005887   GO:0045202   GO:0034220   GO:0007268   GO:0050877   GO:0007165   GO:0042391   GO:0005216   GO:0006810   GO:0016020   GO:0022891   GO:0003707   GO:0051537  

PANTHER

PTHR18945  

Length:

527

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

79.4107400000001

Exp number, first 60 AAs:

0.00011

Total prob of N-in:

0.22863

outside

1  -  279

TMhelix

280  -  302

inside

303  -  310

TMhelix

311  -  328

outside

329  -  342

TMhelix

343  -  365

inside

366  -  487

TMhelix

488  -  510

outside

511  -  527

 

 

Pi

264.442158

Theta

180.158876

Tajima's D

1.253777

CLR

0.030074

CSRT

0.726613669316534

Interpretation

Uncertain