SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO07751
Pre Gene Modal
BGIBMGA001256
Annotation
PREDICTED:_low-density_lipoprotein_receptor-related_protein_4-like_[Bombyx_mori]
Location in the cell
Cytoplasmic   Reliability : 1.09 Extracellular   Reliability : 1.518 Nuclear   Reliability : 1.193
 

Sequence

CDS
ATGCCAGCACCGATCGTCGTTTATATCATTTCATTCTTCTTCTTTTGGCTGTACGTGCTTGCGGATGAACCGATCGGCCAAAATGGACCTCGAGCAACAAACAATTCGGTGGATGCACCGGACCCTCGCTCTCCTTTGGGCAGAGTACCACCATATCAACCACCGCCGGCAGGAATGGGAGTAGGTCCCAATCCAATGAATTCTCCGGGATTTTGGCCACACGGCATCTATACTCGCGTTGAAGGCTGGCATCATCGGCCAAGCCTTCAAAAGGCGATTGATGTGATTCACACCGACCCGGATGATGGACCCCTCAACGAAGGGACAGAAGACGACGCAGGCTGTATTACACCTTGCCTCAAAATCAATTTCTCGTGTCAGATATCCTGCACGTGCATTCCTATGGAAAAACGTTGCGATGGAATTGCTGATTGTGCCGAAGCCGAAGATGAGGCCGGCTGCGCGAGATCCTGTGACGAACATGAAAACCGTACCATTTGTCACAGCACAAATGTGTGCATCGCTTTAGAATGGCTCTGCGATGGAGACAATGACTGCGGGGATTTCTCGGATGAGATCAATTGCGGTGCACCTACAAATTGTACAGCCGATCAATTCCAATGCTCCAACGGCCTATGCATTCATAAAGGATGGGTGTGTGATGGTGACAACGATTGTCGTGACAACTCAGACGAAACTAATTGCACTAAAGGAAGATGTCGTGAAAACCAGTTTACTTGTGCCGTCGGCGAATGCATCTCTCAACATTGGAGATGTGATCACGAACCCGACTGTCCTGATAGCTCTGACGAAGCCGACTGTCCGGTGGAGCTCATGCGTTGCGCAGAAATCGATTTTGAATGCAAAAACACGAAATGCGTTCCCAAGGATTTCCAGTGCGACGGCGACAACGACTGTGGCGACTGGACAGACGAAGACTCGTGCCCAATGGTGCCTGGAAGTTGCAACGCTGGCGAATTCAAATGCAACGACGGCAAATGTATACCGGAAAGATGGCGATGTGACAACGAAAGGGACTGTGCAGACGGTGGAGATGAACTAAACTGCAAACCAAATAGCATACGAAATTGTTCATTAGATGAATATACTTGCGCTGATCGAAGATGTGTACTGAAAACCTGGCTCTGTGATGGAGTTCGGGATTGCACTAATGGTGAAGATGAAATGAACTGCGAAGTTAGCTGCGAAGAAGATCAATACACTTGTAGGCCTCAAGAACATTTAATGAGTAACGCTTTTAGGAATTGCGTAAACAGGAAGCACGTTTGTGATGGTATGAAGGACTGTCCTCGTGGCGATGATGAAGAACGATGTCCGTTGAAGAGAAAATGTTCTGCCGAGGAAAAATGCGAGAAGTTATGCATTACTACGTACGACGGTCATGCAGCCTGCGCTTGTCCTATGGGATTTTTATTAGCTGAAGATAAATACAGTTGCCGAGACATCGATGAGTGTATGTACGAACAAGATCCAGTATGTTCTCAAACATGTTCCAATACAGTCGGAAGTTTCCGTTGTGGTTGCATGACTGGCTACATCTTAAGACCTGATGAAAGGTCTTGTAAGCCAACAGGCGAATCACCAACACTTCTGTTCTCGAATAGGATTGGGATACGACAGGTGTGGTTAACTGGTGATAATTACATGTCCGTGGTCAAAGGTTTACATAATGCGGTAGCTTTAGACTATCATTACGAAAAGAAACTTGTATTCTGGTCTGAAAATAACTTACGAGTTATCCGTGTTGCGCAAATGAATACAAAAAATATGTCAGATGTCATTAGGTGGGGATTAGAGACACCGGCAGGAGTGGCAGTAGATTGGATACACGATCTTCTCTTCTGGACCGATTCAGGAACAAGAAGAGTTGAAGTGGCAACCCTTGATGGTTCCAAAAGAGCGGTTTTAGTTGCCAACGATTTAGACAAACCACGGGCAATTGCTGTACATCCCGGAGACGCATTAGTATTTTGGACAGACTGGGGTCCTAACCCGAAAATTGAACGTGCTGATATGGATGGCGATAAACGCAAAACTGTTATATATGACGAAATTTTTTGGCCTAACGGACTAACTATTGACTATACGGAATCTAAAATATACTGGGCTGATGCAAAGCACCATGTTATCGAAAGAGCTGCATTTGACGGCCGAGATCGGCGCAAGGTCACAACGAAAGGTCTTCCCCATCCGTTCGCGTTAACACTGTTCGATGATGCCATTTACTGGACAGATTGGCATACGAAAAGCATTTCTACCGTTAATAAGAATACAGGAATGGGTATTCAAACTGTGCATGCTGGACTTAATGTCCCTATGGATATTCATAGTTACCATCCCCTCAGGCAATTAAGAACATACAAAAATAAATGTGGCAAAAGCAACGGAGGCTGTAGTCATCTTTGTCTTCCTAATGCATACGGATTTTCCTGTCGATGTCCAGTTGGCTTCAATTTAAATTCTGACGGTCGATCTTGCGAAGAAACTCCCGAAAAACTATTATTGTATGCTCGGAGGAAAGATTTAAGATTGAAACAACTAGAATCTAAGAAGCCAATAGATTCTTTAGACATGGTTATTCCTGTTGAAACTATTAAATCGGCAGTGGCTTTAGACTGGGATCAGAAAAGTAATTCTATCTTTTGGACGGATGTGGAAAAAGACACAATCAACCGCGCATACCTTAATGGATCCCACCAAACTACTATTGTGGATTCTAACCTCATTTGGCCAGCGGGTTTAGCATTTGATTGGATTACTGATAAAATCTACTGGACCGACGGTGGAACAAACAGAATTGAAGTTTCGAAATCTGATGGTAGTATGAGAACTTTGTTAGCTTGGGATCACATTGATAAACCAAGAGATATTGTTGTTAATCCAGAAGGTGGTGTTATGTACTGGTCTGATTGGGGAGCGAGTCCGTGCATTGAAAGAGCCGATATGGACGGTGGTAATCGCAAAAAACTCATCTTCGGACAAATGACTTGGCCTAACGGATTAGCTTTAGACCTTGTACACAATCGTATTTACTGGACCGATGGTGGAAATAAAACGATTGAGTATGCAAATTTAGACGGAACTGGGAGAACAAAGTTAATTGAAAATTTGCCCCATCCTTTTGGTTTGGATTTGTACGGTGACGAAGTATTTTGGACTGATTGGGACACACAGTCAATTCAAGCTGCCAACAAAGATACTGGAGCTAAACGACGAACACTAGGGTCTGGTGTAGCTGGACTTATGGATGTTAGAGTTTTCCACAAGGAAAGAACAAGCGGCTTTAACAGATGCGGCAAGAATAATGGAGGATGTTCACATTTATGCCTCTTGAAACCAGGAGGACGATCTTGTGCCTGTCCTATCGGTATAAAGCTTAATAAAGATGGTAAAACTTGTGCCGATGGTCCTATCAACTATTTGATTTTTGCACACCGTGTGGATATTCGGGTCATATCATTAGACGTACCGTATCTTATTGACGTCGTATTACCGTTGCCACCACTGAAGAATGCCCTGGGCGTGGATGTCGATCACAGCACAGGTCTAATTTACTGGACTGATACGGGACAAAGGAAAATACAACGCGCAACTAGACTAGGAACACATGTTGAAACTGTAATCGGTAATGGCCTACACACTGCTGACGGTATTGTCATCGATTCAACCGGACGCAAGATATATTGGACTGATGGCGGTCGCAACAGTATCGAAGTGGCAGAACTAGATGGTAGGAATAGGAAAGTACTCGTATGGACTGGCCTAGATTCACCTCGAGCCATAGCATTACATTATGAATACGGTTATATGTTTTGGTCAGACTGGGGAACGTCAGCTAAAATCGAAAGAGCAGATATGGATGGCAATAATCGGCGCGTTATTGTGGACAACAAAATCAAATGGCCTAACGGCCTGGCCATAGATAGAATAGAGGGACGTCTTTATTGGAACGATGCTAAAATTTTAACAATAGAAAGTTCCGACTTTGACGGCCACGATCGACGCACTGTTTTAAGTAACGTTCCATACCCTTACGGAATCGTTATCGTTGGTCAGCATATATATTGGACCGATTGGAAGACCAAAGCATTACACAGAGCTGACAAGACTAACGCTTCGGATCCAATAGTTATAAGAAAAAATCTAGAAGGCTTAATGGATATCAGAGCGATTCAGAGTGAACGTGTTTTGGAAAATGCATGTGGTACTGATAATGGCGGGTGTTCTCATCTTTGCCTTCGGTCACCACTCGGCTACACATGTGCGTGTCCAACGGGTATGCCATTCGAAAAAAGCACAACCGACCAAACGCCAAAGAAATGCAAGTCACATCCTGAAGAATTTTTAATATTTGCCACTAGAGGAAGTATTACTTACATTTCTCTTGAAAGTCCCGAGCAGTGGGATGTTACTCTTCCAGTCAAAGAAGTGAAAAATACCATCGCCGTGGACTATCATTGGGACTTAAAGATGATCTTTTATACAGATCTTGATCTGAATGTGATAAGGTCTATAAATATGACGAACATGAGTGAAAGCAAAACAATTATCTCTCAGAAATTGGAAACTCCAAACGGTTTGGGTGTTGATTGGATTGCAAATAATATCTATTGGACGGATAATGAACATAAGGTTATTGAGGTTGCAAGGTTGGACGGATCATCAAGAAAAGTACTCATAACTGGTCTAACTGAACCAAGAGCTTTAGCATTGTTTCCAGCAAAAGGGTATTTATATTGGAGTGATTGGGGTGAACATCCATATATAGAGAGGTCTTACTTAGATGGTAGCCAAAGGCAGATTATCGTGCAAGTTGACTTGGGTTTCCCTAATGGTCTAACAATAGATTACAAAGAAAGAAGACTTTATTGGACTGACGCGCTTAAGGATAGAATTGATACGTCTGATTTAAATGGACAGCATCGAGTCCAACTTGTTCCAGACGCAAAGAACCCTTTTGGAATGACGCAGTTTAAAGATTATATTTACTGGACGGATTGGTACAAAAAATCCATTATCAGAGCAGATAAAAGAACAGGGAAAAACATAACGTTGATCAGAACCAATCTGGAGATGGCGATGGAGATCAAGGCTGTTTCAGCGGACCGCCAGCATGGATGGAACCCGTGCAAGGAATCTAACGGTGGATGTTCACACTTATGCCTTTTCAGAGGCCATGAATATATTTGCGCCTGCCCAGATGATCCGGATCATGTAGAATGCTCAACTGTACCAAAATTCCTGATCGAAAATATCCTTCCGGCGCATTACCCGCCTTACTACGACTATTCTGATATAGAGTTTAAGAAAACAGTAAGGCCCCCACCGACCCCTAGTCCGGACTATTTTGGCAGATGCATGATGGCTGGAGGGATAATATTAATTTCTATTTTAGCATTTCTCTTCGTCACGATTTATTGCGTGAAAATGCTCCGAAATTATCGAGACACTGAACTGAAAGACGAAGAGTTCAGCAATTCTACCGGTCACATATCTTTTCACAATCCAAATTATAGCTGCGCAACGGGAGGTCCGGGGGGTAACGGCCCTGATCATATTGAGCGTCGACAAAATCGATTTCAAGGAATCTTCAAGTACGACAAACAGCAGGAGCGGGTAACGAACGTGTACTACCCTGAGGGAACCAGTTTGCTGCCCACACCTACGCCTCCTCCACCCCAAAGACAAGCCCTCACGACGACAAAGCGACCGCCCACGCATGATGACTTCGAACCGGTGACACTGCACTCCTACGCTTGA
Protein
MPAPIVVYIISFFFFWLYVLADEPIGQNGPRATNNSVDAPDPRSPLGRVPPYQPPPAGMGVGPNPMNSPGFWPHGIYTRVEGWHHRPSLQKAIDVIHTDPDDGPLNEGTEDDAGCITPCLKINFSCQISCTCIPMEKRCDGIADCAEAEDEAGCARSCDEHENRTICHSTNVCIALEWLCDGDNDCGDFSDEINCGAPTNCTADQFQCSNGLCIHKGWVCDGDNDCRDNSDETNCTKGRCRENQFTCAVGECISQHWRCDHEPDCPDSSDEADCPVELMRCAEIDFECKNTKCVPKDFQCDGDNDCGDWTDEDSCPMVPGSCNAGEFKCNDGKCIPERWRCDNERDCADGGDELNCKPNSIRNCSLDEYTCADRRCVLKTWLCDGVRDCTNGEDEMNCEVSCEEDQYTCRPQEHLMSNAFRNCVNRKHVCDGMKDCPRGDDEERCPLKRKCSAEEKCEKLCITTYDGHAACACPMGFLLAEDKYSCRDIDECMYEQDPVCSQTCSNTVGSFRCGCMTGYILRPDERSCKPTGESPTLLFSNRIGIRQVWLTGDNYMSVVKGLHNAVALDYHYEKKLVFWSENNLRVIRVAQMNTKNMSDVIRWGLETPAGVAVDWIHDLLFWTDSGTRRVEVATLDGSKRAVLVANDLDKPRAIAVHPGDALVFWTDWGPNPKIERADMDGDKRKTVIYDEIFWPNGLTIDYTESKIYWADAKHHVIERAAFDGRDRRKVTTKGLPHPFALTLFDDAIYWTDWHTKSISTVNKNTGMGIQTVHAGLNVPMDIHSYHPLRQLRTYKNKCGKSNGGCSHLCLPNAYGFSCRCPVGFNLNSDGRSCEETPEKLLLYARRKDLRLKQLESKKPIDSLDMVIPVETIKSAVALDWDQKSNSIFWTDVEKDTINRAYLNGSHQTTIVDSNLIWPAGLAFDWITDKIYWTDGGTNRIEVSKSDGSMRTLLAWDHIDKPRDIVVNPEGGVMYWSDWGASPCIERADMDGGNRKKLIFGQMTWPNGLALDLVHNRIYWTDGGNKTIEYANLDGTGRTKLIENLPHPFGLDLYGDEVFWTDWDTQSIQAANKDTGAKRRTLGSGVAGLMDVRVFHKERTSGFNRCGKNNGGCSHLCLLKPGGRSCACPIGIKLNKDGKTCADGPINYLIFAHRVDIRVISLDVPYLIDVVLPLPPLKNALGVDVDHSTGLIYWTDTGQRKIQRATRLGTHVETVIGNGLHTADGIVIDSTGRKIYWTDGGRNSIEVAELDGRNRKVLVWTGLDSPRAIALHYEYGYMFWSDWGTSAKIERADMDGNNRRVIVDNKIKWPNGLAIDRIEGRLYWNDAKILTIESSDFDGHDRRTVLSNVPYPYGIVIVGQHIYWTDWKTKALHRADKTNASDPIVIRKNLEGLMDIRAIQSERVLENACGTDNGGCSHLCLRSPLGYTCACPTGMPFEKSTTDQTPKKCKSHPEEFLIFATRGSITYISLESPEQWDVTLPVKEVKNTIAVDYHWDLKMIFYTDLDLNVIRSINMTNMSESKTIISQKLETPNGLGVDWIANNIYWTDNEHKVIEVARLDGSSRKVLITGLTEPRALALFPAKGYLYWSDWGEHPYIERSYLDGSQRQIIVQVDLGFPNGLTIDYKERRLYWTDALKDRIDTSDLNGQHRVQLVPDAKNPFGMTQFKDYIYWTDWYKKSIIRADKRTGKNITLIRTNLEMAMEIKAVSADRQHGWNPCKESNGGCSHLCLFRGHEYICACPDDPDHVECSTVPKFLIENILPAHYPPYYDYSDIEFKKTVRPPPTPSPDYFGRCMMAGGIILISILAFLFVTIYCVKMLRNYRDTELKDEEFSNSTGHISFHNPNYSCATGGPGGNGPDHIERRQNRFQGIFKYDKQQERVTNVYYPEGTSLLPTPTPPPPQRQALTTTKRPPTHDDFEPVTLHSYA

Summary

Similarity
Belongs to the ligand-gated ion channel (TC 1.A.9) family.
EMBL
BABH01001078    BABH01001079    BABH01001080    ODYU01001638    SOQ38142.1    NWSH01000440    + More
PCG76408.1    KZ149987    PZC75664.1    AGBW02008449    OWR53342.1    KQ459606    KPI91197.1    JTDY01001259    KOB74369.1    KQ459700    KPJ20387.1    GEZM01083947    JAV60918.1    KK852422    KDR24262.1    DS235842    EEB18264.1    KQ971338    EFA01584.1    KYB28118.1    NNAY01001070    OXU25251.1    NEVH01004410    PNF39646.1    AXCN02001227    ATLV01003048    KE524109    KFB34887.1    AAAB01008846    EAA06523.5    CH477684    EAT37281.1    CVRI01000063    CRL04825.1    GAMC01020434    GAMC01020432    GAMC01020430    GAMC01020428    JAB86121.1    CCAG010015965    JRES01001701    KNC20826.1    CH916370    EDW00413.1    JXJN01009101    JXJN01019975    CH940651    EDW65320.2    CH964291    EDW86389.2    CP012528    ALC49629.1    CH933810    EDW07296.2    OUUW01000011    SPP86422.1    APCN01004087    GBYB01002393    JAG72160.1    CH902621    KPU81707.1    CH954180    KQS30270.1    EDV46935.1    CM000162    EDX01855.1    KRK06381.1    KRK06382.1    BT046152    AE014298    ACI46540.1    ACZ95304.1    AHN59777.1    AAF48538.1    GBYB01002391    JAG72158.1    KPU81708.1    AXCP01007151    GDIP01035334    JAM68381.1    GDIQ01139505    JAL12221.1    GDIQ01048190    JAN46547.1    GDIQ01076673    JAN18064.1    GDIQ01090321    JAN04416.1    GDIQ01137106    JAL14620.1    GL732617    EFX70780.1    GDIQ01152951    JAK98774.1    GDIQ01169544    JAK82181.1    GDIQ01057033    JAN37704.1    GDIQ01155698    JAK96027.1    GDIQ01113866    JAL37860.1    GDIP01111617    JAL92097.1    GDIQ01180836    JAK70889.1    GDIQ01005018    JAN89719.1    GDIQ01034694    JAN60043.1    GDIQ01179089    JAK72636.1    GDIQ01147255    JAL04471.1    GDIQ01217526    JAK34199.1    GDIQ01066188    JAN28549.1    LRGB01003123    KZS04260.1    LSYS01003385    OPJ82897.1    AGTO01000953    KL215509    KFV64968.1    KB742689    EOB05435.1    AADN05000303    KL870451    KGL88496.1    OPJ82896.1    AKCR02000005    PKK31201.1    KK949629    KFQ57252.1    AGCU01167968    AGCU01167969    AGCU01167970    AGCU01167971    AGCU01167972    ADON01035509    KK629297    KFV54836.1    AKHW03006283    KYO21756.1    QRBI01000144    RMC00329.1   
Pfam
PF00057   Ldl_recept_a        + More
PF07645   EGF_CA
PF00058   Ldl_recept_b
PF02931   Neur_chan_LBD
PF02932   Neur_chan_memb
PF12662   cEGF
Interpro
IPR013032   EGF-like_CS        + More
IPR018097   EGF_Ca-bd_CS       
IPR000742   EGF-like_dom       
IPR011042   6-blade_b-propeller_TolB-like       
IPR023415   LDLR_class-A_CS       
IPR000033   LDLR_classB_rpt       
IPR001881   EGF-like_Ca-bd_dom       
IPR036055   LDL_receptor-like_sf       
IPR002172   LDrepeatLR_classA_rpt       
IPR009030   Growth_fac_rcpt_cys_sf       
IPR018000   Neurotransmitter_ion_chnl_CS       
IPR006201   Neur_channel       
IPR036734   Neur_chan_lig-bd_sf       
IPR006202   Neur_chan_lig-bd       
IPR006029   Neurotrans-gated_channel_TM       
IPR036719   Neuro-gated_channel_TM_sf       
IPR000152   EGF-type_Asp/Asn_hydroxyl_site       
IPR026823   cEGF       
SUPFAM
SSF57424   SSF57424        + More
SSF57184   SSF57184       
SSF63712   SSF63712       
SSF90112   SSF90112       
Gene 3D
PDB
4DG6     E-value=1.61077e-161,     Score=1467

Ontologies

Topology

SignalP
Position:   1 - 21,         Likelihood:  0.940742
 
 
Length:
1926
Number of predicted TMHs:
2
Exp number of AAs in TMHs:
38.02424
Exp number, first 60 AAs:
16.60458
Total prob of N-in:
0.90646
POSSIBLE N-term signal
sequence
inside
1  -  4
TMhelix
5  -  22
outside
23  -  1792
TMhelix
1793  -  1815
inside
1816  -  1926
 
 

Population Genetic Test Statistics

Pi
265.87692
Theta
201.564518
Tajima's D
1.221087
CLR
0.154992
CSRT
0.71786410679466
Interpretation
Uncertain
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