Gene

KWMTBOMO07694

Pre Gene Modal

BGIBMGA001276

Annotation

PREDICTED:_cytochrome_P450_CYP12A2_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr13(-):4501044-4518140      View in EpiBrowser

Full name

Cytochrome P450 CYP12A2      

Alternative Name

CYPXIIA2

Location in the cell

Mitochondrial   Reliability : 1.394 Nuclear   Reliability : 1.797

CDS

ATGATAATAGCCCTGCATTACAGTAAACTGAGACCGGTGTTGAATTTCTCGTGTCTGCAGCAATGTGTGAGAACAGTGACAGTTAGCGCGGCAACAGAAAAACTACAACAAACAGAATTGAAATCGTTTCGAGAGATTCCGGGCCCCTCGTCGTTGCCGATCATGGGCCCGTTTCTACACTTCATGCCCGGAGGATCCCTTCACAACATTAACAGCACGGAACTGACTCACAAACTGTACGACATATACGGACCTATCGTTAGAATCGATTCAATGTTTTCTAAGGACGCTATTGTATTACTGTATGATGCAGAAAGCGCCGGAATCATTTTACGTAACGAGAACAACATGCCAATAAGGATCAGCTTTAAATCCTTATCATATTATAGACAGAAATATAAGAAATCGGAAAATGATCGCACAGACAGACCGACTGGATTAGTGTCAGACCACGGCGAGTTATGGAAGAGCTTCCGTTCGGCGGTGAATCCAGTCTTATTACAGCCGAAAACTATAAGACTATACAGCTCAGCACTAGAAGAGGTAGCCACCGACATGGTCGAGAGGCTTAGGTCTCTTAGAGATGAAAACAACAGGATACGTGGTCAATTCGATCAAGAGATGAATCTTTGGTCTCTCGAATCAATAGGGGTTGTGGCTTTAGGAAACCGGCTTAACTGCTTCGATTCAAATCTTCAGGACGACTCCCCCGTCAAGAGATTGATCGAATGTGTCCATCAGATGTTCGTGTTATCGAACGAATTGGACCTCAAGCCCAGTATTTGGACGTATGTTTCAACACCGCTATTCAGGAAAACTATGAAAATGTATGAAGAACAAGAAAATTTAACGAAATATTTCATCAAGAAAGCACTAGACGATATTAAAATGAACAAATCGAAATCGGATGATGAGAAACCGGTGCTCGAGAAATTATTGGACATCAATGAAGAATACGCGTATATTATGGCTTCAGACATGCTGGTGGCTGGTGTCGATACCACTTCAAACACGATGTCCGCAACTTTGTACCTCATGGCGATAAATCAGGACAAACAGCAGAAGTTGAGGGAAGAAGTGATGTCGAAGAACGGTAAAAGATCATACTTGAGGGCTTGCATCAAAGAGGCCATGAGAATACTACCAGTCGTGTCCGGGAACATGCGACGCACCACAAAGGAGTACAACATTCTTGGATATCATATACCGGAAAATGTCGACATTGCATTTGCTCATCAACATTTGTCGATGATGGAGAAATACTATCCAAGACCGACGGAGTTCATTCCTGAACGCTGGTTGACTAACAAGAGCGATCCTCTTTATTATGGAAACGCGCATCCATTCGCGAATTCCCCATTCGGCTTCGGTGTTCGCAGCTGTATAGGTCGTCGCATCGCCGAATTAGAAGTGGAAACATTTTTGTCGAAGATCGTCGAAAATTTTCAAGTCGAGTGGTCGGGGTCATCCCCTAGAGTCGAACAGACTTCCATCAATTACTTCAAGGGACCTTTTAACTTTATATTCAAAGATCTTTAA

Protein

MIIALHYSKLRPVLNFSCLQQCVRTVTVSAATEKLQQTELKSFREIPGPSSLPIMGPFLHFMPGGSLHNINSTELTHKLYDIYGPIVRIDSMFSKDAIVLLYDAESAGIILRNENNMPIRISFKSLSYYRQKYKKSENDRTDRPTGLVSDHGELWKSFRSAVNPVLLQPKTIRLYSSALEEVATDMVERLRSLRDENNRIRGQFDQEMNLWSLESIGVVALGNRLNCFDSNLQDDSPVKRLIECVHQMFVLSNELDLKPSIWTYVSTPLFRKTMKMYEEQENLTKYFIKKALDDIKMNKSKSDDEKPVLEKLLDINEEYAYIMASDMLVAGVDTTSNTMSATLYLMAINQDKQQKLREEVMSKNGKRSYLRACIKEAMRILPVVSGNMRRTTKEYNILGYHIPENVDIAFAHQHLSMMEKYYPRPTEFIPERWLTNKSDPLYYGNAHPFANSPFGFGVRSCIGRRIAELEVETFLSKIVENFQVEWSGSSPRVEQTSINYFKGPFNFIFKDL

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Keywords

Complete proteome   Heme   Iron   Metal-binding   Monooxygenase   Oxidoreductase  

Feature

chain  Cytochrome P450 CYP12A2

Uniprot

L0N5L2   L0N6M0   H9IVJ6   L0N731   D5L0N7   A0A068ETR9   + More
D5L0N6   A0A2A4JB57   J7FIT7   A0A286QUH6   A0A248QEI8   A0A194PD37   A0A194PCV8   A0A0C5C533   A0A0C5C1H5   D2JLK5   A0A194QYD6   A0A1V0D9G9   A0A1V0D9G5   A0A212ERS8   H9IVJ7   A0A1E1WBR0   A0A1E1W6Z4   A0A1E1WJG1   A0A346II03   A0A212F2K7   A0A1V0D9I0   A0A194QYL5   A0A1E1WN58   A0A1E1WAC2   A0A194QZ45   A0A0N0PEW1   A0A068EWM5   A0A286MXN7   A0A194PNU6   J7FJF8   A0A212EU53   A0A248QEI9   A0A194QSH9   D5L0N5   L0N6I8   A0A3S2PF19   A0A0L7LAT5   A0A0C5C1L2   A0A182MHV7   A0A2H1WI68   A0A340TBF6   A0A1I8MP30   A0A336K3T6   A0A182PZ56   A0A023ETJ1   A0A182H3M9   O18635   A0A1S4GX15   K7J4S2   Q5TQM6   A0A182II69   A0A182UM32   A0A182XUR2   A0A182XUR0   A0A084VBX5   Q86QN3   A0A1S4GXQ5   Q17JN3   A0A1W6R7J5   Q86QN4   A0A182VHC9   A0A1L8E4A8   A0A182II71   A0A1L8E3Y1   A0A1L8E4J3   A0A1L8E4I2   A0A182S4Q4   A0A026X4P4   A0A182FZU6   A0A336MMT9   A0A2J7RNN8   A0A182PZ54   A0A1A9VZ41   B4KTY6   U5EHF6   A0A1Q3FJK3   A0A1Q3FR33   B0WTS5   A0A2M4AJC1   A0A1I8N7Q7   A0A182IJQ1   A0A2M4AI68   B0WTS3   A0A1S4JS48   A0A2J7PBF7   A0A068F5B4   A0A336MA77  

EC Number

1.14.-.-

Pubmed

19121390    19909380    28756777    22984814    28881445    26354079    + More
19954531    22118469    25299618    26227816    25315136    24945155    26483478    12364791    20075255    24438588    14585502    17510324    24508170    30249741    17994087    25880816   

EMBL

AK343196    AK343202    BAM73885.1    BAM73888.1    AK343201    BAM73887.1    + More
BABH01001230    BABH01001231    AK289309    BAM73836.1    GU731542    ADE05592.1    KM016710    KZ149946    AID54862.1    PZC76746.1    GU731541    ADE05591.1    NWSH01002099    PCG69201.1    JX310099    AFP20610.1    KX443481    ASO98056.1    KX443480    ASO98055.1    KQ459606    KPI91147.1    KPI91146.1    KP001115    AJN91160.1    KP001116    AJN91161.1    GQ915321    ACZ97415.1    KQ460947    KPJ10553.1    KY212080    ARA91644.1    KY212081    ARA91645.1    AGBW02012935    OWR44198.1    BABH01001232    GDQN01010473    GDQN01006630    JAT80581.1    JAT84424.1    GDQN01008311    JAT82743.1    GDQN01003905    JAT87149.1    MH138217    AXP17158.1    AGBW02010730    OWR47956.1    KY212082    ARA91646.1    KPJ10552.1    GDQN01002676    JAT88378.1    GDQN01007130    JAT83924.1    KPJ10554.1    KQ459668    KPJ20511.1    KM016709    AID54861.1    MF684355    ASX93989.1    KQ459599    KPI94419.1    JX310098    AFP20609.1    AGBW02012491    OWR44987.1    KX443479    ASO98054.1    KQ461154    KPJ08442.1    GU731540    ADE05590.1    AK289310    BAM73837.1    RSAL01000062    RVE49588.1    JTDY01001897    KOB72593.1    KP001114    AJN91159.1    AXCM01012394    ODYU01008822    SOQ52761.1    UFQS01000086    UFQT01000086    SSW99091.1    SSX19473.1    GAPW01000938    JAC12660.1    JXUM01024875    JXUM01074800    JXUM01074801    KQ562852    KQ560704    KXJ75006.1    KXJ81216.1    U94698    AAAB01008964    AAZX01005602    EAL39670.1    APCN01002484    ATLV01009808    KE524547    KFB35469.1    AY176050    AAO19581.1    CH477232    EAT46807.2    KX688011    ARO50443.1    AY176049    AAO19580.1    GFDF01000620    JAV13464.1    GFDF01000636    JAV13448.1    GFDF01000619    JAV13465.1    GFDF01000629    JAV13455.1    KK107021    QOIP01000011    EZA62389.1    RLU17085.1    UFQS01001766    UFQT01001766    SSX12271.1    SSX31722.1    NEVH01002150    PNF42438.1    CH933808    EDW10712.2    GANO01003040    JAB56831.1    GFDL01007245    JAV27800.1    GFDL01005067    JAV29978.1    DS232091    EDS34539.1    GGFK01007397    MBW40718.1    GGFK01007150    MBW40471.1    EDS34537.1    NEVH01027097    PNF13669.1    KJ702264    AID61418.1    UFQS01000790    UFQT01000790    SSX06908.1    SSX27252.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000283053    + More
UP000037510    UP000075883    UP000075920    UP000095301    UP000075885    UP000069940    UP000249989    UP000002358    UP000007062    UP000075840    UP000075903    UP000076407    UP000030765    UP000008820    UP000075900    UP000053097    UP000279307    UP000069272    UP000235965    UP000091820    UP000009192    UP000002320    UP000075880   

PRIDE

L0N5L2    L0N6M0    H9IVJ6    L0N731    H9IVJ7    L0N6I8    + More
O18635   

Pfam

PF00067   p450

Interpro

IPR036396   Cyt_P450_sf        + More
IPR002401   Cyt_P450_E_grp-I       
IPR001128   Cyt_P450       
IPR017972   Cyt_P450_CS       
IPR002403   Cyt_P450_E_grp-IV       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

L0N5L2   L0N6M0   H9IVJ6   L0N731   D5L0N7   A0A068ETR9   + More
D5L0N6   A0A2A4JB57   J7FIT7   A0A286QUH6   A0A248QEI8   A0A194PD37   A0A194PCV8   A0A0C5C533   A0A0C5C1H5   D2JLK5   A0A194QYD6   A0A1V0D9G9   A0A1V0D9G5   A0A212ERS8   H9IVJ7   A0A1E1WBR0   A0A1E1W6Z4   A0A1E1WJG1   A0A346II03   A0A212F2K7   A0A1V0D9I0   A0A194QYL5   A0A1E1WN58   A0A1E1WAC2   A0A194QZ45   A0A0N0PEW1   A0A068EWM5   A0A286MXN7   A0A194PNU6   J7FJF8   A0A212EU53   A0A248QEI9   A0A194QSH9   D5L0N5   L0N6I8   A0A3S2PF19   A0A0L7LAT5   A0A0C5C1L2   A0A182MHV7   A0A2H1WI68   A0A340TBF6   A0A1I8MP30   A0A336K3T6   A0A182PZ56   A0A023ETJ1   A0A182H3M9   O18635   A0A1S4GX15   K7J4S2   Q5TQM6   A0A182II69   A0A182UM32   A0A182XUR2   A0A182XUR0   A0A084VBX5   Q86QN3   A0A1S4GXQ5   Q17JN3   A0A1W6R7J5   Q86QN4   A0A182VHC9   A0A1L8E4A8   A0A182II71   A0A1L8E3Y1   A0A1L8E4J3   A0A1L8E4I2   A0A182S4Q4   A0A026X4P4   A0A182FZU6   A0A336MMT9   A0A2J7RNN8   A0A182PZ54   A0A1A9VZ41   B4KTY6   U5EHF6   A0A1Q3FJK3   A0A1Q3FR33   B0WTS5   A0A2M4AJC1   A0A1I8N7Q7   A0A182IJQ1   A0A2M4AI68   B0WTS3   A0A1S4JS48   A0A2J7PBF7   A0A068F5B4   A0A336MA77  

PDB

3K9Y     E-value=1.80457e-35,     Score=375

KEGG

101744617    K15004 cytochrome P450 family 12 [EC:1.14.-.-] | (RefSeq) CYP333B1; cytochrome P450 CYP12A2

GO

GO:0005506   GO:0016705   GO:0020037   GO:0004497   GO:0046872   GO:0046983   GO:0015935   GO:0016573   GO:0008270   GO:0022891   GO:0003707   GO:0051537   GO:0055114  

Length:

512

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.04012

Exp number, first 60 AAs:

0.00375

Total prob of N-in:

0.00141

outside

1  -  512

 

 

Pi

217.671875

Theta

180.838475

Tajima's D

0.389272

CLR

0.12339

CSRT

0.47727613619319

Interpretation

Uncertain