Gene

KWMTBOMO07677

Annotation

reverse_transcriptase_[Lasius_niger]

Location

Bomo_Chr13(-):4316409-4319100      View in EpiBrowser

Full name

Probable RNA-directed DNA polymerase from transposon X-element       + More
RNA-directed DNA polymerase from mobile element jockey      

Alternative Name

Reverse transcriptase

Location in the cell

Mitochondrial   Reliability : 1.873 Nuclear   Reliability : 2.513

CDS

ATGCACCCAGATGGCTCCGCCCACGGAGGAAGTGCAATTATAATCAGAAGTAACATCAAGCACTATGAAGGATCTCATTACTGTACTGATATAATACAAGCAACAAACATCGTTGTTCAAGACTGGGTGGGACCCATCACCATATCGGCACTTTACAGCCCTCCAAAACATAACATTAAGAATGAAGATTATGAAAAGTTTTTTAATTCCTTAGGACATAGATTTATGGCTGGTGGAGATTATAATGCTAAGCATACAAGCTGGGGGTCTCGAACTGTGACAACGAAGGGAAGACAGTTACTTTCTTGCATTGAACGACTAAGATTAAATGTTTGTTCAACTGGCGAGCCAACATATTGGCCGAGTGACAAAAGGAAGGTACCAGACTTGTTAGATTTTTGTATCACAAAAGGCATCAATAATGCATGTATAGAGTGTACATCCAGTTTTGATCTCTCATCTGATCACTCCCCAGTCATAATAACGCTCAGTCGAAATATAGCCAGGAAAATGAAAACATGTAGACTGCATTCTTGCAGGACCGATTGGGATTACTTTCGTGTATTGGTATCTGGCTCTTTGGACATCAATCTACCTCTAAAAACAGAGGATGACATTGCGGATGGTGTTGAACATTTTAACTTTGTTGTACAACATTCTGCTTGGCAGGCGACACCCGCCCCACCAATTGTAAAACCATCGCAATGTTCTCTTTCAATCAAAACGTTGTTATCAGAAAAAAGGCGATTAAGAAAACGATGGCAAACTACGAGGCATCCTGATGACAAAAAAATATTTAATTACAGTATTACAAAATTGAAAATACATTTGGCTCGTGAGAGAAACGAAAAAACAAATACATATATGCAAGAGCTGGATGCCACATCGAAAACAGACTATTCGCTATGGAAGGCTACCAAATACCTTAAACGTCCTATAAACCACCAACCTCCTCTACGGAAATCTGATGGAACTTGGGCCACTAGCGATCTAGACAAAGCTAAGGCCTTTGCTGAACACCTGGATTATGTATTTACACCAAATGCGATGGATAATTCGGCTATGCCTCCCAATGAATCGGAATTGAATGAGCATGTTATTGAGGTTTCCTTCAAAAAAATTCGTAAATCCGAAACAAGATCTGTCATAAAGAATCTTGACCCTAATAAATCACCAGGATATGATCTAATAACAGCAACTATTTTAAAAGAGTTACCTCAAGAGGGAATTACTTTCTTGACCCAATTATACAATGCTATTTTCAGACTTAAGTTTGTGCCTCACTTATGGAAGGTAGCTCAAATTAAGATGATACCTAAACCTGGAAAAAGTGGCGAGGACGTGAAATCTTATCGTCCTATCAGTTTGCTCCCTGTACCGTCCAAGGTCATGGAGATTCTGTTTCTTACAAGATTGAATCCTATTATTGAAACGAAAAAACTAATCCCAGATCATCAGTTTGGCTTTAGACGGAAACATAGTACAATCGAACAAATTCACAGACTTGTTGAATATATTAATAGAGCTTTTGAGGGAAAAAAATACTGCACGGCTGCCTTCCTAGATATATCTCAGGCCTTCGACCGAGTTTGGCATGAAGGACTCTTACTCAAAATTAAAAAGAAGATCCCTTCCAACTTCTATTTTTTCATTGAATCTTATTTGAGTAGCCGATATTATTTTGTTAAACACGGCGATGAAATATCGCCTCTCCATTCAATTAATGCCGGTGTTCCCCAAGGCAGTGTCATTGGGCCCACTTTATATCTATTGTATACAGCTGATTTGCCCGAAACTGATGGTACGATAATGGGAACTTTTGCTGATGACACCGCAATAATGACCATGGACGATGATCCAAACGAAGCTTCTTATAAACTACAGAACAGCCTTAATAATATCAACACTTGGCTAAAAAAATGGTGTATCAAAGCGAATGAATCTAAGTCTGTACAAGTTACTTTCACCACTCGAAGACAAACTTGTCCTGCAGTCACCTTGAATAATATAGAGATCCCGCAATCTGAAAATGCAAAGTACTTAGGGATGTACCTGGATAGGAGACTGACTTGGAGAAAACATATATTAACCAAGCGTCTTGCGGTGGGTCAGCAAATACGTAAATTGTATTGGCTTCTTAATAGAAAGTCTCAACTGTCAGTTGAAAACAAGCTTTTACTATACAAATCTGTTATTAAACCCATTTGGTCATATGGCATCCAATTGTGGGGTACTGCGTCAAACTCAAATATTGAAATACTTCAAAGATTTCAATCAAAAACGCTCAGGATGATAGTGAACGCACCATGGTATGTTACAAATGAAAGAATCCATTATGATCTTGCCATAAGAAAAGTCAAACATGAAGTAATCCATCGAGCTAAAGCATATTGTGTAAGATTGGAAGCCCATCCGAATAACCTTGCTAAGCATTTAATGGACAACCTAATGACTACTAGAAGACTCAGAAGAAGAGTGCCTCAAGATCTACTAGATCTACTGTAG

Protein

MHPDGSAHGGSAIIIRSNIKHYEGSHYCTDIIQATNIVVQDWVGPITISALYSPPKHNIKNEDYEKFFNSLGHRFMAGGDYNAKHTSWGSRTVTTKGRQLLSCIERLRLNVCSTGEPTYWPSDKRKVPDLLDFCITKGINNACIECTSSFDLSSDHSPVIITLSRNIARKMKTCRLHSCRTDWDYFRVLVSGSLDINLPLKTEDDIADGVEHFNFVVQHSAWQATPAPPIVKPSQCSLSIKTLLSEKRRLRKRWQTTRHPDDKKIFNYSITKLKIHLARERNEKTNTYMQELDATSKTDYSLWKATKYLKRPINHQPPLRKSDGTWATSDLDKAKAFAEHLDYVFTPNAMDNSAMPPNESELNEHVIEVSFKKIRKSETRSVIKNLDPNKSPGYDLITATILKELPQEGITFLTQLYNAIFRLKFVPHLWKVAQIKMIPKPGKSGEDVKSYRPISLLPVPSKVMEILFLTRLNPIIETKKLIPDHQFGFRRKHSTIEQIHRLVEYINRAFEGKKYCTAAFLDISQAFDRVWHEGLLLKIKKKIPSNFYFFIESYLSSRYYFVKHGDEISPLHSINAGVPQGSVIGPTLYLLYTADLPETDGTIMGTFADDTAIMTMDDDPNEASYKLQNSLNNINTWLKKWCIKANESKSVQVTFTTRRQTCPAVTLNNIEIPQSENAKYLGMYLDRRLTWRKHILTKRLAVGQQIRKLYWLLNRKSQLSVENKLLLYKSVIKPIWSYGIQLWGTASNSNIEILQRFQSKTLRMIVNAPWYVTNERIHYDLAIRKVKHEVIHRAKAYCVRLEAHPNNLAKHLMDNLMTTRRLRRRVPQDLLDLL

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

At least 30 copies of X-element are present in the genome and some elements are polymorphic between different strains.
Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  Probable RNA-directed DNA polymerase from transposon X-element

Uniprot

A0A0J7MYU2   A0A2J7R4U3   A0A2J7Q9Z1   A0A2J7QES2   A0A2J7PSM7   A0A2J7R7D0   + More
A0A2J7R098   A0A2J7RQ52   A0A2J7PMN4   A0A2J7PVX3   A0A2J7QB68   A0A2A4K918   A0A2A4IUM2   J9LYS0   A0A2J7PDM0   A0A2J7Q0S7   A0A0J7K4E0   A0A1Y1KFR3   A0A1Y1LKN6   A0A0A9YU04   A0A0A9YJ00   A0A2J7RD70   A0A142LX26   A0A0J7K811   A0A1B6EGD8   A0A142LX53   A0A2J7PVE7   A0A034VFD2   A0A142LX49   Q6R811   Q04135   A0A0J7K7J8   A0A0M4EWX7   Q961V7   Q24335   A0A224X6T4   A0A0J7NDW4   A0A352X8G4   A0A224XHW8   A0A1L8DIZ6   A0A069DX78   A0A2S2NGV8   A0A0V0G5B6   A0A0A9YSX4   A0A2J7R8R8   A0A2S2N814   A0A224XJI0   A0A224X746   A0A023F0I3   A0A224X6R6   A0A2S2PJG2   A0A2S2N6Q7   A0A224X6W2   A0A224X724   A0A224X6S1   A0A224X6U5   A0A2S2P698   A0A224XIB0   X1WUG2   A0A2S2NH02   A0A2S2P6S3   A0A224XI99   A0A2S2R9D4   A0A2S2NPJ7   A0A2H8TKI9   A0A2H8TF37   A0A2S2PHL7   A0A023F069   A0A0J7K3N0   A0A2S2QDN9   A0A2S2P6C4   A0A1Y1MT28   A0A2S2PUS3   A0A2S2P7B2   A0A2S2P3X8   J9KE07   A0A146KRW8   A0A146KV64   A0A1B6C2V8   J9KSK5   A0A2S2NKC3   J9M0H4   A0A224XK92   X1XLN5   Q9NBX4   A0A2S2QEE0   A0A2S2PA10   A0A2S2NPG3   J9KWJ0   A0A224X7Z3   J9M4H5   X1WVQ4   A0A2S2N9P4   A0A2S2PBB4   J9LMA3   J9KLB1   A0A224XIV5   P21328  

EC Number

2.7.7.49

Pubmed

28004739    25401762    25527032    25348373    14745026    1705654    + More
2441397    30148503    26334808    25474469    26823975    11405632    2463954    3040362    1714378   

EMBL

LBMM01013518    KMQ85605.1    NEVH01007402    PNF35856.1    NEVH01016340    PNF25410.1    + More
NEVH01015305    PNF27092.1    NEVH01021925    PNF19341.1    NEVH01006736    PNF36716.1    NEVH01008277    PNF34262.1    NEVH01001347    PNF42959.1    NEVH01023979    PNF17579.1    NEVH01020940    PNF20481.1    NEVH01016302    PNF25823.1    NWSH01000032    PCG80496.1    NWSH01007753    PCG62823.1    ABLF02041861    NEVH01026386    PNF14434.1    NEVH01019963    PNF22185.1    LBMM01014395    KMQ85192.1    GEZM01084969    JAV60363.1    GEZM01053022    JAV74219.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    NEVH01005295    PNF38784.1    KU543673    AMS38352.1    LBMM01012078    KMQ86419.1    GEDC01000337    JAS36961.1    KU543687    AMS38379.1    NEVH01020963    PNF20308.1    GAKP01017773    JAC41179.1    KU543685    AMS38375.1    AY508487    AAS13459.1    X17551    CAA35587.1    LBMM01012041    KMQ86458.1    CP012527    ALC48130.1    AY047531    AAK77263.1    M17214    AAA28508.1    GFTR01008261    JAW08165.1    LBMM01006314    KMQ90710.1    DNOY01000259    HBE18313.1    GFTR01008254    JAW08172.1    GFDF01007661    JAV06423.1    GBGD01000389    JAC88500.1    GGMR01003407    MBY16026.1    GECL01003538    JAP02586.1    GBHO01008295    JAG35309.1    NEVH01006721    PNF37225.1    GGMR01000676    MBY13295.1    GFTR01008257    JAW08169.1    GFTR01008151    JAW08275.1    GBBI01003747    JAC14965.1    GFTR01008269    JAW08157.1    GGMR01016905    MBY29524.1    GGMR01000226    MBY12845.1    GFTR01008260    JAW08166.1    GFTR01008169    JAW08257.1    GFTR01008271    JAW08155.1    GFTR01008251    JAW08175.1    GGMR01012305    MBY24924.1    GFTR01008246    JAW08180.1    ABLF02016613    GGMR01003864    MBY16483.1    GGMR01012443    MBY25062.1    GFTR01008256    JAW08170.1    GGMS01017365    MBY86568.1    GGMR01006491    MBY19110.1    GFXV01002840    MBW14645.1    GFXV01000908    MBW12713.1    GGMR01016296    MBY28915.1    GBBI01003810    JAC14902.1    LBMM01015125    KMQ84919.1    GGMS01006655    MBY75858.1    GGMR01012283    MBY24902.1    GEZM01021881    JAV88842.1    GGMR01020516    MBY33135.1    GGMR01012676    MBY25295.1    GGMR01011511    MBY24130.1    ABLF02024784    ABLF02024792    GDHC01020244    JAP98384.1    GDHC01018248    JAQ00381.1    GEDC01029594    JAS07704.1    ABLF02014118    ABLF02014121    ABLF02054790    GGMR01005022    MBY17641.1    ABLF02034460    GFTR01007997    JAW08429.1    ABLF02017755    ABLF02044739    ABLF02063495    ABLF02065698    ABLF02066197    AF237761    AAF81411.1    GGMS01006359    MBY75562.1    GGMR01013409    MBY26028.1    GGMR01006408    MBY19027.1    ABLF02021819    ABLF02021820    ABLF02055326    GFTR01007929    JAW08497.1    ABLF02017668    ABLF02021394    ABLF02055728    ABLF02023279    ABLF02041474    GGMR01000857    MBY13476.1    GGMR01014053    MBY26672.1    ABLF02025048    ABLF02063033    ABLF02040174    ABLF02040183    ABLF02055266    GFTR01007904    JAW08522.1    M22874    M38643   

Proteomes

UP000036403    UP000235965    UP000218220    UP000007819    UP000092553   

PRIDE

Q04135    Q961V7    Q24335    Q9NBX4    P21328   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       

SUPFAM

SSF56219   SSF56219       

Gene 3D

3.60.10.10    

ProteinModelPortal

A0A0J7MYU2   A0A2J7R4U3   A0A2J7Q9Z1   A0A2J7QES2   A0A2J7PSM7   A0A2J7R7D0   + More
A0A2J7R098   A0A2J7RQ52   A0A2J7PMN4   A0A2J7PVX3   A0A2J7QB68   A0A2A4K918   A0A2A4IUM2   J9LYS0   A0A2J7PDM0   A0A2J7Q0S7   A0A0J7K4E0   A0A1Y1KFR3   A0A1Y1LKN6   A0A0A9YU04   A0A0A9YJ00   A0A2J7RD70   A0A142LX26   A0A0J7K811   A0A1B6EGD8   A0A142LX53   A0A2J7PVE7   A0A034VFD2   A0A142LX49   Q6R811   Q04135   A0A0J7K7J8   A0A0M4EWX7   Q961V7   Q24335   A0A224X6T4   A0A0J7NDW4   A0A352X8G4   A0A224XHW8   A0A1L8DIZ6   A0A069DX78   A0A2S2NGV8   A0A0V0G5B6   A0A0A9YSX4   A0A2J7R8R8   A0A2S2N814   A0A224XJI0   A0A224X746   A0A023F0I3   A0A224X6R6   A0A2S2PJG2   A0A2S2N6Q7   A0A224X6W2   A0A224X724   A0A224X6S1   A0A224X6U5   A0A2S2P698   A0A224XIB0   X1WUG2   A0A2S2NH02   A0A2S2P6S3   A0A224XI99   A0A2S2R9D4   A0A2S2NPJ7   A0A2H8TKI9   A0A2H8TF37   A0A2S2PHL7   A0A023F069   A0A0J7K3N0   A0A2S2QDN9   A0A2S2P6C4   A0A1Y1MT28   A0A2S2PUS3   A0A2S2P7B2   A0A2S2P3X8   J9KE07   A0A146KRW8   A0A146KV64   A0A1B6C2V8   J9KSK5   A0A2S2NKC3   J9M0H4   A0A224XK92   X1XLN5   Q9NBX4   A0A2S2QEE0   A0A2S2PA10   A0A2S2NPG3   J9KWJ0   A0A224X7Z3   J9M4H5   X1WVQ4   A0A2S2N9P4   A0A2S2PBB4   J9LMA3   J9KLB1   A0A224XIV5   P21328  

PDB

1WDU     E-value=0.00214725,     Score=100

KEGG

105842636    no KO assigned | (RefSeq) RNA-directed DNA polymerase from mobile element jockey-like

GO

GO:0003964   GO:0006313  

Length:

834

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01697

Exp number, first 60 AAs:

0.00072

Total prob of N-in:

0.00005

outside

1  -  834

 

 

Pi

163.538229

Theta

85.95493

Tajima's D

2.116408

CLR

0.406608

CSRT

0.900054997250137

Interpretation

Uncertain