Gene

KWMTBOMO07656

Pre Gene Modal

BGIBMGA000854

Annotation

PREDICTED:_GDP-fucose_transporter_1_[Papilio_xuthus]

Location

Bomo_Chr13(+):3263766-3269247      View in EpiBrowser

Full name

GDP-fucose transporter 1      

Alternative Name

Neuronally altered carbohydrate
Solute carrier family 35 member C1 homolog

Location in the cell

PlasmaMembrane   Reliability : 4.888

CDS

ATGAAGTCTCAGCAATCGGAATTATGTTCTCTCTATACCAAGATATTCGTAGTGGTTTCTTGTTACTGGGTGGTGTCAATAGTGACAGTATTTGTTAATAAGACACTATTCAGCAGTCAAACAGTGGCTCTTGAGGCGCCTCTATTCATAACTTGGTTCCAGTGTATAATTTCATTCTCAATTTGTTTTACATTGAGTCAAAATGGTGGAGTTCCTGGTATATTTTCCTTTCCAAAAGGAACACCTTGGAGTATGGACGTCATGAAAAAGGTGATTCCACTGGCAATAATGTATACTTTGATGATAGCCACAAATAATTTGTGTTTGAAGCATGTAGGAGTACCGTTCTATTATGTAGGAAGATCTCTGACCACAGTCTTCAATGTTGTATTTAGCTGGATATTATTAAGACAGGCAACATCGTCCAGATGTATTTTGTGCTGCGCCTTCATTATATTCGGATTCTATCTTGGAGTTGATCAAGAAAACTTATTAGGGTCATTTTCCCTTATAGGAACAATCTATGGAGTGGTTGGTTCCCTCATGCTATCCTTGTACTCTATATTCACAAAGAAGGTTTTACCATATGTTAACCAAGAAGTATTGTTATTGTCGTACTACAATAATGCATACTCCATAATACTTTTCATACCGCTAATGTTAATCAACGGAGAAATGACAGTTTTGATGAACTACACTAATTTCCAAAGCACCTACTTCTGGTTTCAAATGGTAATAGGTGGTCTATGCGGTTTTGCAATAGGATACTGTACTTCTCTACAGATAAAGGTAACATCACCTCTGACACACAATATATCTGGCACAGCAAAGGCTTGTGCGCAAACGGTGATCGCGACGCAGTGGTACAACGAAAGTAAAAATGCGCTTTGGTGGACGTCCAATTTAATAGTACTAGCCAGTTCAGCTTTATACGCAAGATTCAAGCAGTTGGAGATGGAAGTTAAATCAAAGACGCCAGTGCCTGAAGAAAAACAGAGCTTAGTATAA

Protein

MKSQQSELCSLYTKIFVVVSCYWVVSIVTVFVNKTLFSSQTVALEAPLFITWFQCIISFSICFTLSQNGGVPGIFSFPKGTPWSMDVMKKVIPLAIMYTLMIATNNLCLKHVGVPFYYVGRSLTTVFNVVFSWILLRQATSSRCILCCAFIIFGFYLGVDQENLLGSFSLIGTIYGVVGSLMLSLYSIFTKKVLPYVNQEVLLLSYYNNAYSIILFIPLMLINGEMTVLMNYTNFQSTYFWFQMVIGGLCGFAIGYCTSLQIKVTSPLTHNISGTAKACAQTVIATQWYNESKNALWWTSNLIVLASSALYARFKQLEMEVKSKTPVPEEKQSLV

Description

Involved in GDP-fucose import from the cytoplasm into the Golgi lumen. Plays a major role in the fucosylation of N-glycans. Functions redundantly with Efr in the O-fucosylation of Notch, positively regulating Notch signaling.

Similarity

Belongs to the TPT transporter family. SLC35C subfamily.

Keywords

Complete proteome   Golgi apparatus   Membrane   Reference proteome   Sugar transport   Transmembrane   Transmembrane helix   Transport  

Feature

chain  GDP-fucose transporter 1

Uniprot

A0A2A4K7Z0   A0A212ESA0   A0A2H1V8F2   A0A194PJ54   A0A194QYI2   A0A1E1WLY0   + More
H9IUC4   A0A336L574   K7J4T3   A0A336MX09   A0A0K8UBE2   S4PNA2   A0A232F149   A0A1B0CBG2   A0A182MRR5   A0A0C9RP07   A0A1L8DED5   A0A1L8DEZ0   A0A182VX57   A0A1I8MES2   A0A154PKX3   A0A088ASJ3   W8C917   A0A0L0CRU3   A0A1I8PRB0   A0A1Q3FB01   A0A0M9A9E3   A0A1S4FGL2   B0WS63   Q171Y2   A0A0M3QXP1   B4NAF1   B4M5Q2   A0A0K8TRY9   A0A2A3EDK5   U5EJR6   A0A067QUH2   A0A182G1I3   A0A3B0JQL9   B3M0D2   A0A1W4VHG1   Q298H3   A0A182QHB8   A0A182GCP6   B4K7W1   B4PT36   Q9VHT4   B3NZU7   B4HLM5   A0A084W1P0   A0A1A9WY54   A0A182NA86   A0A182VD60   A0A182R3N3   A0A182PA61   A0A182F8D0   A0A1A9UZ23   A0A182IVJ0   A0A182TU73   A0A182XI94   E2BEE2   A0A182LFB2   Q7QC10   A0A182HT81   B4JH27   D3TRG4   A0A1J1HXS6   A0A1A9Z9M3   A0A182JX79   A0A1B6E6Z6   A0A1B6K0M0   A0A2M4BTH8   A0A2M4BTP3   A0A2M4BTN7   W5JKP2   A0A1B6F945   A0A1A9XG71   A0A195C7J3   A0A1B0BQ30   A0A1B0GAV4   A0A158NMV8   A0A026W5L1   E2B0K8   A0A1B6LE31   N6SRR0   A0A195EWR2   J3JV05   A0A1S3DHQ6   A0A1Y1N0R0   A0A182SDQ1   F4WT95   A0A195BB45   A0A151WHH2   A0A151IYP0   A0A1W4XDX3   J9JP93   A0A182YKI2   D6X1P8   A0A2S2Q391   A0A0A9Z075  

Pubmed

22118469    26354079    19121390    20075255    23622113    28648823    + More
25315136    24495485    26108605    17510324    17994087    26369729    24845553    26483478    15632085    17550304    10731132    12537572    19948734    22745127    24438588    20798317    20966253    12364791    14747013    17210077    20353571    20920257    23761445    21347285    24508170    30249741    23537049    22516182    28004739    21719571    25244985    18362917    19820115    25401762    26823975   

EMBL

NWSH01000056    PCG80126.1    AGBW02012839    OWR44365.1    ODYU01001210    SOQ37115.1    + More
KQ459606    KPI91115.1    KQ460947    KPJ10522.1    GDQN01003021    JAT88033.1    BABH01001346    UFQS01001768    UFQT01001768    SSX12281.1    SSX31732.1    AAZX01000449    UFQT01002153    SSX32787.1    GDHF01028428    JAI23886.1    GAIX01000972    JAA91588.1    NNAY01001281    OXU24506.1    AJWK01005120    AXCM01000651    GBYB01008886    JAG78653.1    GFDF01009278    JAV04806.1    GFDF01009164    JAV04920.1    KQ434948    KZC12473.1    GAMC01002554    JAC04002.1    JRES01000007    KNC34936.1    GFDL01010291    JAV24754.1    KQ435710    KOX79925.1    DS232065    EDS33686.1    CH477443    EAT40804.1    CP012526    ALC46209.1    CH964232    EDW80765.1    CH940652    EDW58978.1    GDAI01000913    JAI16690.1    KZ288271    PBC29780.1    GANO01002136    JAB57735.1    KK852996    KDR12701.1    JXUM01023446    KQ560661    KXJ81388.1    OUUW01000007    SPP82672.1    CH902617    EDV43138.1    CM000070    EAL27982.1    AXCN02000218    JXUM01054531    KQ561824    KXJ77423.1    CH933806    EDW14295.1    CM000160    EDW96497.1    AE014297    BT003501    CH954181    EDV49945.1    CH480815    EDW43052.1    ATLV01019399    KE525269    KFB44134.1    GL447768    EFN85987.1    AAAB01008859    EAA08101.2    APCN01000421    CH916369    EDV92718.1    EZ424016    ADD20292.1    CVRI01000026    CRK92354.1    GEDC01003606    JAS33692.1    GECU01002722    JAT04985.1    GGFJ01007234    MBW56375.1    GGFJ01007232    MBW56373.1    GGFJ01007233    MBW56374.1    ADMH02001252    ETN63460.1    GECZ01023053    JAS46716.1    KQ978231    KYM96131.1    JXJN01018364    CCAG010010901    ADTU01020821    KK107432    QOIP01000001    EZA50901.1    RLU27501.1    GL444634    EFN60768.1    GEBQ01018022    JAT21955.1    APGK01058833    KB741292    KB632334    ENN70314.1    ERL92758.1    KQ981940    KYN32715.1    BT127070    AEE62032.1    GEZM01015649    GEZM01015648    JAV91492.1    GL888334    EGI62558.1    KQ976529    KYM81753.1    KQ983115    KYQ47286.1    KQ980745    KYN13656.1    ABLF02037531    KQ971371    EFA10140.1    GGMS01002964    MBY72167.1    GBHO01006851    GBRD01004034    GDHC01007077    JAG36753.1    JAG61787.1    JAQ11552.1   

Proteomes

UP000218220    UP000007151    UP000053268    UP000053240    UP000005204    UP000002358    + More
UP000215335    UP000092461    UP000075883    UP000075920    UP000095301    UP000076502    UP000005203    UP000037069    UP000095300    UP000053105    UP000002320    UP000008820    UP000092553    UP000007798    UP000008792    UP000242457    UP000027135    UP000069940    UP000249989    UP000268350    UP000007801    UP000192221    UP000001819    UP000075886    UP000009192    UP000002282    UP000000803    UP000008711    UP000001292    UP000030765    UP000091820    UP000075884    UP000075903    UP000075900    UP000075885    UP000069272    UP000078200    UP000075880    UP000075902    UP000076407    UP000008237    UP000075882    UP000007062    UP000075840    UP000001070    UP000183832    UP000092445    UP000075881    UP000000673    UP000092443    UP000078542    UP000092460    UP000092444    UP000005205    UP000053097    UP000279307    UP000000311    UP000019118    UP000030742    UP000078541    UP000079169    UP000075901    UP000007755    UP000078540    UP000075809    UP000078492    UP000192223    UP000007819    UP000076408    UP000007266   

PRIDE

H9IUC4    Q9VHT4   

Pfam

PF03151   TPT        + More
PF05485   THAP

Interpro

IPR004853   Sugar_P_trans_dom        + More
IPR029666   GDP-fucose_transp       
IPR038441   THAP_Znf_sf       
IPR006612   THAP_Znf       

Gene 3D

3.30.40.180    

ProteinModelPortal

A0A2A4K7Z0   A0A212ESA0   A0A2H1V8F2   A0A194PJ54   A0A194QYI2   A0A1E1WLY0   + More
H9IUC4   A0A336L574   K7J4T3   A0A336MX09   A0A0K8UBE2   S4PNA2   A0A232F149   A0A1B0CBG2   A0A182MRR5   A0A0C9RP07   A0A1L8DED5   A0A1L8DEZ0   A0A182VX57   A0A1I8MES2   A0A154PKX3   A0A088ASJ3   W8C917   A0A0L0CRU3   A0A1I8PRB0   A0A1Q3FB01   A0A0M9A9E3   A0A1S4FGL2   B0WS63   Q171Y2   A0A0M3QXP1   B4NAF1   B4M5Q2   A0A0K8TRY9   A0A2A3EDK5   U5EJR6   A0A067QUH2   A0A182G1I3   A0A3B0JQL9   B3M0D2   A0A1W4VHG1   Q298H3   A0A182QHB8   A0A182GCP6   B4K7W1   B4PT36   Q9VHT4   B3NZU7   B4HLM5   A0A084W1P0   A0A1A9WY54   A0A182NA86   A0A182VD60   A0A182R3N3   A0A182PA61   A0A182F8D0   A0A1A9UZ23   A0A182IVJ0   A0A182TU73   A0A182XI94   E2BEE2   A0A182LFB2   Q7QC10   A0A182HT81   B4JH27   D3TRG4   A0A1J1HXS6   A0A1A9Z9M3   A0A182JX79   A0A1B6E6Z6   A0A1B6K0M0   A0A2M4BTH8   A0A2M4BTP3   A0A2M4BTN7   W5JKP2   A0A1B6F945   A0A1A9XG71   A0A195C7J3   A0A1B0BQ30   A0A1B0GAV4   A0A158NMV8   A0A026W5L1   E2B0K8   A0A1B6LE31   N6SRR0   A0A195EWR2   J3JV05   A0A1S3DHQ6   A0A1Y1N0R0   A0A182SDQ1   F4WT95   A0A195BB45   A0A151WHH2   A0A151IYP0   A0A1W4XDX3   J9JP93   A0A182YKI2   D6X1P8   A0A2S2Q391   A0A0A9Z075  

PDB

5OGK     E-value=0.00208662,     Score=96

KEGG

101745911    K15279 solute carrier family 35 (GDP-fucose transporter), member C1 | (RefSeq) GDP-fucose transporte

GO

GO:0005457   GO:0016021   GO:0036085   GO:0005794   GO:0048193   GO:0036066   GO:0007625   GO:0005798   GO:0036071   GO:0015783   GO:1990569   GO:0072334   GO:0015789   GO:1990570   GO:0008643   GO:0015786   GO:0015782   GO:0000139   GO:0015787   GO:0022857   GO:0015297   GO:0003677   GO:0030176   GO:0030173  

PANTHER

PTHR11132:SF255  

Subcellular location

Golgi apparatus membrane  

Length:

335

Number of predicted TMHs:

9

Exp number of AAs in TMHs:

174.17752

Exp number, first 60 AAs:

34.86875

Total prob of N-in:

0.21612

POSSIBLE N-term signal

sequence

outside

1  -  14

TMhelix

15  -  37

inside

38  -  48

TMhelix

49  -  71

outside

72  -  90

TMhelix

91  -  109

inside

110  -  113

TMhelix

114  -  136

outside

137  -  139

TMhelix

140  -  159

inside

160  -  163

TMhelix

164  -  186

outside

187  -  200

TMhelix

201  -  223

inside

224  -  239

TMhelix

240  -  262

outside

263  -  294

TMhelix

295  -  314

inside

315  -  335

 

 

Pi

162.250424

Theta

148.479907

Tajima's D

0.180905

CLR

0.617753

CSRT

0.420778961051947

Interpretation

Uncertain