Gene

KWMTBOMO07630

Pre Gene Modal

BGIBMGA000843

Annotation

PREDICTED:_glycine_receptor_subunit_alpha-4_[Bombyx_mori]

Location

Bomo_Chr13(+):2158521-2219372      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 3.641

CDS

ATGCGACCTCCAGCTCGGAAGGGGCAGCCTGTCATCGTGGAGTTCAGTATATATGTTGTTGATGTTAACTCCATCAATGTCGAAGATATGGATTTTCGTGTGGATATGTTCATAAGACAGACTTGGAGTGAGAGTCGGCTGCAGCTGCCCGAAGATATATTTGAAGAGGGAGACGACCACGTCACCCTGCCTCCAGAATTCTTCGACAATCTGTGGCATCCCGATCCTTATTTCTTGAACTCAAAAGTGACTGAAATCGCCGAATTGACTCATAAGTTTTCATCAGTGACGCTGTACAGGAATCAGACCGTTCGATATTCAGCTCGGATGCACGCCATCATCGCGTGCCAAATGGAATTTCAACTTTATCCCATGGACATACAGTCGTGTCCTATCTACATAGAGAGCTTCTCATATAGCAATCAGAAAGTGAGGTTCCGTTGGAGCGAAGCAGGGGTCACCATAAATCCTGAACTGAAACTGCTGCAGTACCACATCGGGCAACCGTTGCGGCTAGAAGAGACCAACGGATACATGATCGATAAGGACGGAAACTACTCCAGACTGGTTGTGTACTTCAGGTTTGAACGTCAAATCGGTCACCACCTCATCCAGACCTTCGCGCCGTCGTCACTGGTAGTTATGCTCTCGTGGTTTAGCTTCTGGCTGGATCTAGATGCTATTCCTGGTCGAGTTACTTTGCTGGTTACCTGCATGCTGACCTTGGTCACGATGTTTACTGGATTGAGAGCTGATATTCCCCCAGTTGCCTATGTGAAGGCTTTAGATTTATGGATGGCTGGTTGCATGATGTTCGTCTTCGCCGCCCTCGGAGAGTTCGTAGTCGTCAAGGTGCTGGACAAGCAATACCAGATGAACAAGAACAAAGCGCAGGAGTCTATGCCGAGGATCATACCAGTGCGTCTGAATGGAGATAAAGGATCGTGTGGCACTATTGCCGCTTGGGAAGGCTCAGGTGTCCGGTGCAGGAAGGTGGATATCACTTCTCCGACTTCCCCTGCAGCAGCCACTCCAGCAGTACATCCCACTCCATCTGCCACAACACCACATGTGGTGGGAGTGGAAAGAAGACAAAGTATATTACAGGTTGCCTGGCTGGATGCTGACACCGGACAGGAGAGAGTGCTGTGGAGAGAAATAGACAAGCTTTCCCGCGTGGTGTTCCCTGCTTTGTTCCTGCTCTTCGTTACGATGTATTGGCCTGTTTTGCTGCTGAAAACAAAGGCTTCTTCATAA

Protein

MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRVTLLVTCMLTLVTMFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIPVRLNGDKGSCGTIAAWEGSGVRCRKVDITSPTSPAAATPAVHPTPSATTPHVVGVERRQSILQVAWLDADTGQERVLWREIDKLSRVVFPALFLLFVTMYWPVLLLKTKASS

Similarity

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Uniprot

H9IUB3   A0A2A4JIU6   A0A212EX87   A0A194PCY9   A0A194QL15   A0A182FKG6   + More
B4LPI7   A0A1S4H4P0   B4KUC0   A0A0K8VDD7   A0A034VQS3   B0WV67   A0A182VJH4   Q7QE21   A0A182KV08   A0A182I608   A0A182G4N2   Q17E21   A0A182Q8J1   A0A182YAC4   A0A1A9XUT7   W8BGG3   A0A1I8QF36   A0A084WUD2   A0A067RIF1   B4J9E1   A0A3B0J038   A0A2J7PYY8   B3MIL3   A0A0R1DNI4   A0A0M4E404   B4NN79   A0A0Q5VXG7   A0A1W4VCX4   B4QAP0   B3NN42   Q8SWZ1   B4P825   B4HN11   A0A336LTE5   A0A0Q9X8V8   Q28XK8   A0A0R3NPK5   B4GGA3   A0A1W4VQM7   A0A0R1DQU8   A0A0Q5VXQ3   A0A0J9RA02   A0A0B4LF41   A0A3B0J428   A0A0Q9X9N7   A0A0R3NUI5   A0A0Q9XG40   A0A0P8XRS2   A0A0J9RAY5   A0A0R3NUY3   A0A0J9R9X6   A0A0P8YEB7   A0A1B0D767   A0A0R3NPW1   A0A0R3NPF0   A0A0R3NQ76   A0A0R3NPK1   A0A1A9Z1W0   A0A182WE73   A0A1B0C2F4   A0A182JBH6   A0A0A1X0C6   A0A1J1IRM0   A0A182WXY7   A0A182UC84   A0A182PWI2   A0A1I8QF94   A0A0R1DNL4   A0A2M4CKJ7   A0A182NPB1   A0A088A427   Q0GQQ5   A0A1I8NIK4   A0A0R3NPR5   E2AKD4   A0A154NWA5   A0A151IDF8   A0A151XGM0   A0A026W0V0   E9J0Y0   E2BVV3   A0A151IT24   D3UAF5   F4WYE8   A0A0N0U644   A0A158N9L9   A0A195BQ34   A0A1W4X709   A0A1W4WW65   A0A0J7KSH8   A0A195F8B5   A0A2A3EMI0   A8DMV1  

Pubmed

19121390    22118469    26354079    17994087    12364791    25348373    + More
20966253    26483478    17510324    25244985    24495485    24438588    24845553    17550304    22936249    18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    23185243    25830018    16902773    25315136    20798317    24508170    21282665    20087392    20075255    21719571    21347285    17880682    18362917    19820115   

EMBL

BABH01001432    BABH01001433    BABH01001434    BABH01001435    BABH01001436    NWSH01001372    + More
PCG71494.1    AGBW02011804    OWR46110.1    KQ459606    KPI91092.1    KQ461198    KPJ06084.1    CH940648    EDW61246.2    AAAB01008848    CH933808    EDW09716.2    GDHF01015431    JAI36883.1    GAKP01015037    GAKP01015036    GAKP01015035    GAKP01015034    JAC43918.1    DS232119    EDS35406.1    EAA07038.4    APCN01003544    JXUM01042556    JXUM01042557    KQ561329    KXJ78962.1    CH477287    EAT44717.1    AXCN02001819    GAMC01008719    GAMC01008718    GAMC01008717    GAMC01008716    JAB97837.1    ATLV01027079    KE525423    KFB53826.1    KK852485    KDR22803.1    CH916367    EDW01422.1    OUUW01000001    SPP74164.1    NEVH01020341    PNF21536.1    CH902619    EDV38089.1    CM000158    KRJ98895.1    CP012524    ALC40666.1    CH964282    EDW85818.1    CH954179    KQS62905.1    CM000362    CM002911    EDX06545.1    KMY92864.1    EDV56562.1    KQS62906.1    AE013599    AY094938    AAF58743.3    AAM11291.1    EDW90072.1    KRJ98891.1    KRJ98894.1    KRJ98896.1    KRJ98897.1    CH480816    EDW47315.1    UFQT01000099    SSX19889.1    KRG04854.1    KRG04855.1    KRG04857.1    KRG04860.1    CM000071    EAL26308.3    KRT02983.1    CH479183    EDW35523.1    KRJ98893.1    KQS62907.1    KMY92866.1    KMY92867.1    AHN56095.1    AHN56097.1    SPP74163.1    KRG04853.1    KRT02991.1    KRG04858.1    KPU77270.1    KPU77271.1    KPU77273.1    KMY92865.1    KMY92869.1    KRT02989.1    KMY92868.1    KPU77272.1    AJVK01012344    AJVK01012345    AJVK01012346    AJVK01012347    KRT02985.1    KRT02990.1    KRT02988.1    KRT02992.1    KRT02984.1    JXJN01024516    GBXI01009986    JAD04306.1    CVRI01000058    CRL02863.1    KRJ98890.1    GGFL01001611    MBW65789.1    DQ667194    ABG75746.1    KRT02987.1    GL440262    EFN66076.1    KQ434772    KZC03861.1    KQ977991    KYM98309.1    KQ982169    KYQ59507.1    KK107502    EZA49697.1    GL767538    EFZ13505.1    GL451029    EFN80182.1    KQ981064    KYN09911.1    FJ851094    ACZ51426.1    GL888441    EGI60756.1    KQ435737    KOX76901.1    ADTU01009695    KQ976428    KYM87793.1    LBMM01003629    KMQ93303.1    KQ981727    KYN36678.1    KZ288219    PBC32251.1    EF545128    KQ971311    ABU63606.1    EEZ99340.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000069272    + More
UP000008792    UP000009192    UP000002320    UP000075903    UP000007062    UP000075882    UP000075840    UP000069940    UP000249989    UP000008820    UP000075886    UP000076408    UP000092443    UP000095300    UP000030765    UP000027135    UP000001070    UP000268350    UP000235965    UP000007801    UP000002282    UP000092553    UP000007798    UP000008711    UP000192221    UP000000304    UP000000803    UP000001292    UP000001819    UP000008744    UP000092462    UP000092445    UP000075920    UP000092460    UP000075880    UP000183832    UP000076407    UP000075902    UP000075885    UP000075884    UP000005203    UP000095301    UP000000311    UP000076502    UP000078542    UP000075809    UP000053097    UP000008237    UP000078492    UP000002358    UP000007755    UP000053105    UP000005205    UP000078540    UP000192223    UP000036403    UP000078541    UP000242457    UP000007266   

PRIDE

H9IUB3    Q8SWZ1   

Pfam

PF02931   Neur_chan_LBD        + More
PF02932   Neur_chan_memb

Interpro

IPR018000   Neurotransmitter_ion_chnl_CS        + More
IPR006201   Neur_channel       
IPR006029   Neurotrans-gated_channel_TM       
IPR006028   GABAA/Glycine_rcpt       
IPR006202   Neur_chan_lig-bd       
IPR036734   Neur_chan_lig-bd_sf       
IPR036719   Neuro-gated_channel_TM_sf       

SUPFAM

SSF63712   SSF63712        + More
SSF90112   SSF90112       

Gene 3D

2.70.170.10    

ProteinModelPortal

H9IUB3   A0A2A4JIU6   A0A212EX87   A0A194PCY9   A0A194QL15   A0A182FKG6   + More
B4LPI7   A0A1S4H4P0   B4KUC0   A0A0K8VDD7   A0A034VQS3   B0WV67   A0A182VJH4   Q7QE21   A0A182KV08   A0A182I608   A0A182G4N2   Q17E21   A0A182Q8J1   A0A182YAC4   A0A1A9XUT7   W8BGG3   A0A1I8QF36   A0A084WUD2   A0A067RIF1   B4J9E1   A0A3B0J038   A0A2J7PYY8   B3MIL3   A0A0R1DNI4   A0A0M4E404   B4NN79   A0A0Q5VXG7   A0A1W4VCX4   B4QAP0   B3NN42   Q8SWZ1   B4P825   B4HN11   A0A336LTE5   A0A0Q9X8V8   Q28XK8   A0A0R3NPK5   B4GGA3   A0A1W4VQM7   A0A0R1DQU8   A0A0Q5VXQ3   A0A0J9RA02   A0A0B4LF41   A0A3B0J428   A0A0Q9X9N7   A0A0R3NUI5   A0A0Q9XG40   A0A0P8XRS2   A0A0J9RAY5   A0A0R3NUY3   A0A0J9R9X6   A0A0P8YEB7   A0A1B0D767   A0A0R3NPW1   A0A0R3NPF0   A0A0R3NQ76   A0A0R3NPK1   A0A1A9Z1W0   A0A182WE73   A0A1B0C2F4   A0A182JBH6   A0A0A1X0C6   A0A1J1IRM0   A0A182WXY7   A0A182UC84   A0A182PWI2   A0A1I8QF94   A0A0R1DNL4   A0A2M4CKJ7   A0A182NPB1   A0A088A427   Q0GQQ5   A0A1I8NIK4   A0A0R3NPR5   E2AKD4   A0A154NWA5   A0A151IDF8   A0A151XGM0   A0A026W0V0   E9J0Y0   E2BVV3   A0A151IT24   D3UAF5   F4WYE8   A0A0N0U644   A0A158N9L9   A0A195BQ34   A0A1W4X709   A0A1W4WW65   A0A0J7KSH8   A0A195F8B5   A0A2A3EMI0   A8DMV1  

PDB

5VDH     E-value=1.301e-50,     Score=505

KEGG

101746110    no KO assigned | (RefSeq) glycine receptor subunit alpha-4

GO

GO:0005886   GO:0005230   GO:0004888   GO:0016021   GO:1904456   GO:0060012   GO:0042752   GO:1902476   GO:0007268   GO:0034220   GO:0005254   GO:0050877   GO:0042391   GO:0007165   GO:0043005   GO:0005887   GO:0045202   GO:0022852   GO:0006811   GO:0016020   GO:0006810   GO:0005737   GO:0005488   GO:0022891   GO:0003707   GO:0051537   GO:0005216  

PANTHER

PTHR18945  

Length:

418

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

86.1046600000002

Exp number, first 60 AAs:

0.00802

Total prob of N-in:

0.01858

outside

1  -  202

TMhelix

203  -  222

inside

223  -  226

TMhelix

227  -  249

outside

250  -  263

TMhelix

264  -  286

inside

287  -  389

TMhelix

390  -  412

outside

413  -  418

 

 

Pi

221.721506

Theta

160.762377

Tajima's D

1.2592

CLR

0.230775

CSRT

0.728113594320284

Interpretation

Uncertain