Gene

KWMTBOMO07627

Annotation

reverse_transcriptase_[Bombyx_mori]

Location

Bomo_Chr13(+):2079440-2083866      View in EpiBrowser

Full name

RNA-directed DNA polymerase from mobile element jockey       + More
Probable RNA-directed DNA polymerase from transposon BS      

Alternative Name

Reverse transcriptase

Location in the cell

Nuclear   Reliability : 2.438

CDS

ATGATTCTTGTCGCGTTGGAGCCAACCCCGGAGGCCAAAAAGAAAATTTCATGCCTCTCGAAAGTTTGCGGCTTATCCGGGGTCTCCATCGAAGCCCCCCATAAACGTGGCACTCCCGGGCAGTGCTACAGATGCCAGCTATATGGCCACTCGGCGCGTAATTGCCACGCGCGTCCCCGCTGCGTGAAGTGCCTCGGCGATCACGCTACGTTAGATTGCGTTAGAGATAGGGAAACCGCGACCGAACCCCCAAGTTGTGTCCTATGCCTTAAGCAAGGGCACTTCGCGAACTACCGTGGATGTCCTAGGGCTCCGCGCAAGCGTTCAACCCTCCCAGCTCCGCGAACCGTCGGCCCAAAGACTTCGACACCCTCAGTGCCGAAACCTGCCTTCGTGCCGGCTGCAGTTCCCACGGTTTCAGCGTGGAAAAAGCCGCTGCCGTATACGAAGGCGGGAACGCAAACCGCACCCCCGCCCCCGCTCGCGACACGCCCCGCGCCCCAGCCCCTGCTCGCACCTCGCCCCGCGCCCGCGTTCCGCCCCCCGCAACCCTCTGCCGTCAACGACTTCGCGCTCGTGCGCGACTTCGTCACCGCTGTTAACTTCGACCGTCTGCGATCGTTCGCAGACGCGATACCATTCTACAATGCTAACGGACTCGCGCGGCAACGCGATCAAATTTTCGAATTCCTCCGCGATAATCTTGTAGATATTCTATTAGTGCAGGAAACCTGTCTGAAGCCCTCGCGTCGCGACCCGAAAGTCGCGAATTACGTCATGGTTAGGAATGACAGACTCACCGCCTCCAAAGGCGGGATTGCCATTTACTATAGGCGGGCCCTGCACGTTGTCCCTCTCGATACTCCCTCGCTCTCACATATCGAGGCGTCAGTGTGCCGTATCTCGCTGACGGGACACCAGCCGATCGTCATCGCATCCGTTTATCTCCCCCCGGACAAGCCCCTTCTGAGCAGTGACATCGAGTCACTGTTCGGCATGGGAGACTCTGTCATCCTGGCAGGCGATTTAAATTGCCACCACACTAGGTGGAACTGCCATCGTACAAACGTTAACGGTAGGCGTCTCGACGCGTTTATAGACGACCTCACCTTTGAAATAGTCGGTCCCCCAACTCCAACATGTTATCCGTATAACATCGCGCTCCGTCCGAGCACTATAGACCTGGCATTGCTTAGGAACGTAACTCTGCGCTTGCGTTCCATCGAAGCAATGTCAGAGCTCGACTCAGACCACCGACCTGTCGTTATGCAGCTCGGTCGCCCTCACAACCCAGTCACTGTTACGAGGACCATGGTGGATTGGAATAAGCTGAGCACGTGCCTAGCCGACGCCGCTCCGCCAATCCTCCCTTGCGGCCCGGATTCGAATTCATCCCCCGAGGACACCGTCGAATCCATAAACATCATTACCGATCACATCTCTTCCGCGATCATTAGATTTTCAAAAGAAGTCGATGTGGAGGACAGCTTCCACCGCATCAGACTGTCCCCCGATCTTAGGAATCTCTTAAGAGTTAGGAACGCGGCAATCCGGGCCTACGATCGTCTTCCCACGCATTCAAACCGGATTCAGATGCGTCGTCTACAACGCGAAGTCCACTCCCGCTTAAGCGACGCGCGTAACGATAATTGGCATAGTTATCTAGAACAACTCGCGCCCTCCCACCAAGCATACTGGCGACTAGCTAGGACCCTCAAATCCGAAACTACCGCTACTATGCCTCCCCTCATACGCCCTTCAGGCCAACCACCGGCATTCGATGACGATGACAAGGCTGAGCTGCTGGCCGATGCACTGCAAGAGCAGTGCACCACCAGCACTCAACACGCGGACCCCGAACACACCGAGTTAGTCGACAGGGAGGTCGAGCGCAGAGCTTCCCTGCCGCCCTCGGACGCGTTACCCCCCATTACCACTGACGAAGTTAGAGACGCGATCCACAACCTCCAACCTAGGAAGGCACCCGGCTCCGACGGCATCTACAACCGCGCGCTAAAACTCTTGCCAGTCCAACTGATAGCAATGTTGGCTACAATTTTAAATGCCGCTATGACGCACTGCATCTTTCCCGCGGTGTGGAAAGAAGCGGACGTTATCGGTATACATAAGCCGGGCAAACCGACAAACGAAACTTCTAGTTACCGTCCGATTAGTCTCCTCTCGACGATAGGAAAAATTTACGAACGGCTCCTTAGGAAACGCCTCTGGGATTTTGTTACCGCGAACAAAATTCTCATAGACGAACAGTTCGGATTCCGCTCTAAACACTCGTGCGTACAACAAGTGCACCGCCTCACGGAGCACATTCTGATAGGACTAAATAGGCGTAAACAAATCCCGACCGGCGCCCTCTTCTTCGACATCGCGAAGGCGTTCGACAAAGTCTGGCACAACGGTTTAATTTATAAACTGTACAACATGGGAGTGCCAGACAGACTCGTGCTCATCATACGAGACTTCTGGTCGAACCGTTCGTTTCGATATCGAGTAGAGGGAACTCGTTCTCGTCCCCGTCAACTGACCGCCGGAGTCCCGCAAGGCTCCGCGCTCTCCCCGTTATTATTTAGTTTGTATATCAAAGATATACCCCGGTCTCCGGAGACCCATCTAGCGCTCTTCGCCGATGACACGGCTATCTACTACTCGTGTAGGAAGATGTCGCTGCTTCATCGGCGACTCCAGATCGCAGTAGCCACCATGGGACAGTGGTTCCGGAAGTGGCGAATTGACATCAACCCCACGAAAAGCGCAGCGGTGCTTTTCAAAAGGGGTCGCCCTCCGAACATCACTTCGAGCATCCCACTCCGTAGTAGGCGCGCAAACACCTCCGCCGTTAGTCCCATCACTCTCTTTGGCCAGCCCATACCGTGGGTCTCGAAGGTCAAATATCTAGGCGTCACCCTCGACAGAGGGATGACATTCCGTCCCCATATAAAAACGGTACGCGACCGCGCCGCGTTTATTCTAGGACGACTCTATCCAATGCTTTGTAGTCGAAGCAAACTGTCCCTCCGTAATAAGGTAACTCTCTACAAAACTTGTATACGCCCCGTCATGACGTATGCAAGCGTAGTGTTCGCTCACGCAGCCCGCACCCACTTGAAATCCCTTCAGGTTATTCAATCACGATTCTGCAGGATAGCCGTCGGAGCGCCTTGGTTCCTTAGGAATGTGGATCTCCACGACGACCTGGAGCTCGACTCTTTTAATTAA

Protein

MILVALEPTPEAKKKISCLSKVCGLSGVSIEAPHKRGTPGQCYRCQLYGHSARNCHARPRCVKCLGDHATLDCVRDRETATEPPSCVLCLKQGHFANYRGCPRAPRKRSTLPAPRTVGPKTSTPSVPKPAFVPAAVPTVSAWKKPLPYTKAGTQTAPPPPLATRPAPQPLLAPRPAPAFRPPQPSAVNDFALVRDFVTAVNFDRLRSFADAIPFYNANGLARQRDQIFEFLRDNLVDILLVQETCLKPSRRDPKVANYVMVRNDRLTASKGGIAIYYRRALHVVPLDTPSLSHIEASVCRISLTGHQPIVIASVYLPPDKPLLSSDIESLFGMGDSVILAGDLNCHHTRWNCHRTNVNGRRLDAFIDDLTFEIVGPPTPTCYPYNIALRPSTIDLALLRNVTLRLRSIEAMSELDSDHRPVVMQLGRPHNPVTVTRTMVDWNKLSTCLADAAPPILPCGPDSNSSPEDTVESINIITDHISSAIIRFSKEVDVEDSFHRIRLSPDLRNLLRVRNAAIRAYDRLPTHSNRIQMRRLQREVHSRLSDARNDNWHSYLEQLAPSHQAYWRLARTLKSETTATMPPLIRPSGQPPAFDDDDKAELLADALQEQCTTSTQHADPEHTELVDREVERRASLPPSDALPPITTDEVRDAIHNLQPRKAPGSDGIYNRALKLLPVQLIAMLATILNAAMTHCIFPAVWKEADVIGIHKPGKPTNETSSYRPISLLSTIGKIYERLLRKRLWDFVTANKILIDEQFGFRSKHSCVQQVHRLTEHILIGLNRRKQIPTGALFFDIAKAFDKVWHNGLIYKLYNMGVPDRLVLIIRDFWSNRSFRYRVEGTRSRPRQLTAGVPQGSALSPLLFSLYIKDIPRSPETHLALFADDTAIYYSCRKMSLLHRRLQIAVATMGQWFRKWRIDINPTKSAAVLFKRGRPPNITSSIPLRSRRANTSAVSPITLFGQPIPWVSKVKYLGVTLDRGMTFRPHIKTVRDRAAFILGRLYPMLCSRSKLSLRNKVTLYKTCIRPVMTYASVVFAHAARTHLKSLQVIQSRFCRIAVGAPWFLRNVDLHDDLELDSFN

Catalytic Activity

a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)

Cofactor

Mg(2+)
Mn(2+)

Miscellaneous

Prefers poly(rC) and poly(rA) as template and activated DNA is not effective.

Keywords

Nucleotidyltransferase   RNA-directed DNA polymerase   Transferase   Transposable element  

Feature

chain  RNA-directed DNA polymerase from mobile element jockey

Uniprot

Q9XXW0   Q9BPQ0   Q93137   A0A0N1PFV1   O96546   A0A139W8G9   + More
A0A1Y1NA23   A0A139WA11   A0A023EYS8   V5GNJ2   V5GNF3   A0A2S2PPK8   Q07995   A0A2S2Q383   A0A3N5Z7I3   A0A023EZE6   X1WLB2   D7EM17   A0A2M4BD66   A0A2M4CV42   A0A2M4BDA5   A0A2M4BD62   A0A2M4CV52   A0A2M4BD67   A0A087UGF5   A0A224X6Q4   A0A2J7QR37   A0A2M4BDV6   X1WNI2   A0A2J7QY69   A0A2J7PBY3   A0A2J7PU96   A0A2S2QEE0   J9LFC9   J9LC21   X1WQI9   A0A2J7R7D0   J9M522   A0A224XF24   A0A2S2NGV8   A0A2J7Q6J2   A0A224XB44   V9GZF1   A0A224X6T4   A0A2S2N814   A0A224X6S1   X1WZH0   A0A2S2P698   A0A224X746   A0A1Y1KFR3   A0A224XI99   A0A069DZL8   Q8I7P8   P21329   K7IN67   A0A2M4BEF4   A0A2M4BEZ9   A0A224X6U5   A0A2S2R9D4   A0A224X6R6   A0A2H8TF37   A0A0A9YJ00   A0A0A9YU04   A0A2J7PDM0   A0A069DX78   A0A2J7RE85   P21328   A0A2M4CVF1   A0A2M4CVK2   Q95SX7   A0A2J7QB68   A0A224XHW8   A0A0V0G5B6   A0A224XJI0   A0A2A4IUM2   A0A1B6EGD8   A0A2J7PVX3   A0A1W7R682   A0A087UCW3   A0A224X6W2   A0A1Y1LKN6   Q8T9X4   A0A2S2PJG2   A0A142LX26   Q24335   A0A2S2NH02   A0A0A9YSX4   A0A2S2NPG3   A0A2S2PA10   A0A2S2P6C4  

EC Number

2.7.7.49

Pubmed

10333566    26354079    10380107    18362917    19820115    28004739    + More
25474469    8387152    30086797    1327974    26334808    1701254    20075255    25401762    2463954    3040362    1714378    7753626    12537569    25527032    2441397   

EMBL

AB018558    BAA76304.1    AB055391    BAB21761.1    U07847    AAA17752.1    + More
KQ459265    KPJ02064.1    AF081103    AAC72921.1    KQ973342    KXZ75569.1    GEZM01008457    JAV94772.1    KQ971729    KYB24751.1    GBBI01004395    JAC14317.1    GALX01005299    JAB63167.1    GALX01005359    JAB63107.1    GGMR01018716    MBY31335.1    S59870    AAB26437.2    GGMS01002992    MBY72195.1    RPOV01000134    RPJ78669.1    GBBI01004571    JAC14141.1    ABLF02042518    ABLF02057746    KQ973412    EFA12510.2    GGFJ01001844    MBW50985.1    GGFL01005012    MBW69190.1    GGFJ01001842    MBW50983.1    GGFJ01001843    MBW50984.1    GGFL01004957    MBW69135.1    GGFJ01001858    MBW50999.1    KK119692    KFM76444.1    GFTR01008279    JAW08147.1    NEVH01011985    PNF31054.1    GGFJ01001857    MBW50998.1    ABLF02008153    ABLF02008462    ABLF02008464    NEVH01009134    PNF33528.1    NEVH01027074    PNF13841.1    NEVH01021205    PNF19912.1    GGMS01006359    MBY75562.1    ABLF02023911    ABLF02036316    ABLF02036319    ABLF02048663    ABLF02066977    ABLF02022418    NEVH01006736    PNF36716.1    ABLF02024246    GFTR01008038    JAW08388.1    GGMR01003407    MBY16026.1    NEVH01017470    PNF24199.1    GFTR01008262    JAW08164.1    M95171    AAA29354.1    GFTR01008261    JAW08165.1    GGMR01000676    MBY13295.1    GFTR01008271    JAW08155.1    ABLF02034467    GGMR01012305    MBY24924.1    GFTR01008151    JAW08275.1    GEZM01084969    JAV60363.1    GFTR01008256    JAW08170.1    GBGD01000415    JAC88474.1    AY180919    AAN87272.1    M38437    GGFJ01002256    MBW51397.1    GGFJ01002257    MBW51398.1    GFTR01008251    JAW08175.1    GGMS01017365    MBY86568.1    GFTR01008269    JAW08157.1    GFXV01000908    MBW12713.1    GBHO01010547    GBHO01010546    JAG33057.1    JAG33058.1    GBHO01021814    GBHO01010549    JAG21790.1    JAG33055.1    NEVH01026386    PNF14434.1    GBGD01000389    JAC88500.1    NEVH01005277    PNF39135.1    M22874    M38643    GGFL01005122    MBW69300.1    GGFL01005121    MBW69299.1    AY060438    AAL25477.1    NEVH01016302    PNF25823.1    GFTR01008254    JAW08172.1    GECL01003538    JAP02586.1    GFTR01008257    JAW08169.1    NWSH01007753    PCG62823.1    GEDC01000337    JAS36961.1    NEVH01020940    PNF20481.1    GEHC01000968    JAV46677.1    KK119261    KFM75202.1    GFTR01008260    JAW08166.1    GEZM01053022    JAV74219.1    AF456125    AAL57609.1    GGMR01016905    MBY29524.1    KU543673    AMS38352.1    M17214    AAA28508.1    GGMR01003864    MBY16483.1    GBHO01008295    JAG35309.1    GGMR01006408    MBY19027.1    GGMR01013409    MBY26028.1    GGMR01012283    MBY24902.1   

Proteomes

UP000053268    UP000007266    UP000007819    UP000054359    UP000235965    UP000002358    + More
UP000218220   

PRIDE

Q9XXW0    Q9BPQ0    Q93137    Q8I7P8    P21329    P21328    + More
Q95SX7    Q8T9X4    Q24335   

Pfam

PF14529   Exo_endo_phos_2        + More
PF00078   RVT_1
PF07530   PRE_C2HC
PF03372   Exo_endo_phos
PF07727   RVT_2

Interpro

IPR000477   RT_dom        + More
IPR005135   Endo/exonuclease/phosphatase       
IPR036691   Endo/exonu/phosph_ase_sf       
IPR006579   Pre_C2HC_dom       
IPR036875   Znf_CCHC_sf       
IPR001878   Znf_CCHC       
IPR013103   RVT_2       

SUPFAM

SSF56219   SSF56219        + More
SSF57756   SSF57756       

Gene 3D

3.60.10.10    

ProteinModelPortal

Q9XXW0   Q9BPQ0   Q93137   A0A0N1PFV1   O96546   A0A139W8G9   + More
A0A1Y1NA23   A0A139WA11   A0A023EYS8   V5GNJ2   V5GNF3   A0A2S2PPK8   Q07995   A0A2S2Q383   A0A3N5Z7I3   A0A023EZE6   X1WLB2   D7EM17   A0A2M4BD66   A0A2M4CV42   A0A2M4BDA5   A0A2M4BD62   A0A2M4CV52   A0A2M4BD67   A0A087UGF5   A0A224X6Q4   A0A2J7QR37   A0A2M4BDV6   X1WNI2   A0A2J7QY69   A0A2J7PBY3   A0A2J7PU96   A0A2S2QEE0   J9LFC9   J9LC21   X1WQI9   A0A2J7R7D0   J9M522   A0A224XF24   A0A2S2NGV8   A0A2J7Q6J2   A0A224XB44   V9GZF1   A0A224X6T4   A0A2S2N814   A0A224X6S1   X1WZH0   A0A2S2P698   A0A224X746   A0A1Y1KFR3   A0A224XI99   A0A069DZL8   Q8I7P8   P21329   K7IN67   A0A2M4BEF4   A0A2M4BEZ9   A0A224X6U5   A0A2S2R9D4   A0A224X6R6   A0A2H8TF37   A0A0A9YJ00   A0A0A9YU04   A0A2J7PDM0   A0A069DX78   A0A2J7RE85   P21328   A0A2M4CVF1   A0A2M4CVK2   Q95SX7   A0A2J7QB68   A0A224XHW8   A0A0V0G5B6   A0A224XJI0   A0A2A4IUM2   A0A1B6EGD8   A0A2J7PVX3   A0A1W7R682   A0A087UCW3   A0A224X6W2   A0A1Y1LKN6   Q8T9X4   A0A2S2PJG2   A0A142LX26   Q24335   A0A2S2NH02   A0A0A9YSX4   A0A2S2NPG3   A0A2S2PA10   A0A2S2P6C4  

PDB

6AR3     E-value=0.00207555,     Score=102

KEGG

105842121    no KO assigned | (RefSeq) uncharacterized LOC105842121

GO

GO:0003964   GO:0004519   GO:0006313   GO:0008270   GO:0003676   GO:0016021   GO:0033179   GO:0015450   GO:0005737   GO:0005488   GO:0022891   GO:0003707   GO:0051537  

Length:

1077

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.34123

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00003

outside

1  -  1077

 

 

Pi

0

Theta

0

Tajima's D

0

CLR

0.227327

CSRT

0

Interpretation

Uncertain