Gene

KWMTBOMO07623

Pre Gene Modal

BGIBMGA000841

Annotation

PREDICTED:_transmembrane_protease_serine_9-like_[Bombyx_mori]

Location

Bomo_Chr13(+):1925810-1927710      View in EpiBrowser

Full name

Trypsin-3       + More
Trypsin-2      
Trypsin-1      
Trypsin-7      

Alternative Name

Antryp2
Antryp1

Location in the cell

Cytoplasmic   Reliability : 2.972

CDS

ATGGGCATTCTTAAGAAAAAAATGGCCAGTGCCGTCAAGGTCGGTACCTTCGATTTGTCCAGACTTGTTTTGAACGAGGAATTAGATGAAGACGAATCATTACTCGTAGATACGGCAGATAGTAGGATTGTGGGTGGACATGAAACTACTATTGAGGACCATCCTTATCAAGTGTCATTCATTGTCAACAACTCGTATTTTTGTGGTGGCATAATCTTAAGTCAAGATTGGATTATGACCGCCGCACATTGCGCTCAAAATGTCGACCCTACAACAGTGGTGCTGCGGGCTGGTAGCACCTTCCGGAAAAATGGCACCATAATACCAATAGCTTTAGTAGCTAGTCATCCAGAATACGATGACCCTGCTTTCGACAAAGACGTTGCTGTCATGAAAACAGTGAAACCCATGGAGTTTGGAGAGACAATGCAGCCGGTAGCACTGCCAGCTCTGGGGGCGAAGTTGGAGCCGAATTCTGAAATCGTAGTCAGTGGTTGGGGGAGGACAGTGATGGGATAA

Protein

MGILKKKMASAVKVGTFDLSRLVLNEELDEDESLLVDTADSRIVGGHETTIEDHPYQVSFIVNNSYFCGGIILSQDWIMTAAHCAQNVDPTTVVLRAGSTFRKNGTIIPIALVASHPEYDDPAFDKDVAVMKTVKPMEFGETMQPVALPALGAKLEPNSEIVVSGWGRTVMG

Description

Constitutive trypsin that is expressed 2 days after emergence, coinciding with host seeking behavior of the female.
Major function may be to aid in digestion of the blood meal.

Catalytic Activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Similarity

Belongs to the peptidase S1 family.

Keywords

Complete proteome   Digestion   Disulfide bond   Hydrolase   Protease   Reference proteome   Secreted   Serine protease   Signal   Zymogen  

Feature

propeptide  Activation peptide
chain  Trypsin-3

Uniprot

H9IUB1   A0A2H1WLN2   H9IUB0   A0A2A4K471   I3UIJ2   A0A3S2LFV6   + More
A0A194PDK1   A0A0N1PJX5   A0A212FPE2   A0A0L7KY81   A0A194QL10   A0A194PCY4   A0A194PEH2   A0A0N1IQS6   A0A212EWZ2   H9JW07   A0A2H1X0F7   A0A182GAC9   Q5QBG0   A0A1Y9GLX5   Q16PR8   F4MI42   P35037   A0A1S4GXU9   A0A182V8D5   A0A182TJQ8   A0A182U9U3   A0A1Y9J184   A0A182KHH7   A0A1L9WNS2   Q5QBG2   A0A182VGJ0   A0A2C9GTQ1   P35036   A0A1Y9GKV0   A0A1Y9J0J4   A0A2V5J8A4   A0A1Y9J180   P35035   A0A240PM69   A0A1S4H7M9   A0A0A2KWH5   Q7Q344   A0A182UPH4   A0A182LPG3   A0A340TBF8   C5IB65   A0A084VY05   B0XB10   C5IBB9   A0A194PDG5   A0A182UGL3   A0A182U4C7   C5IBC0   A0A084VY04   C5IBB8   B0W771   A0A182XL71   A0A3D8T2K0   C5IB66   P35041   C5IBF5   W5JDQ9   K7J8G2   A0A182ICF6   A0A084VY03   A0A2V5HHZ2   L0ATN6   A0A182FPP1   C5IB64   C5IB79   A0A2C9GTS0   C5IB68   A0A194RI37   A0A182V8R1   C5IB72   C5IBE8   A0A2A3E9B5   A0A182T724   A0A240PL37   Q29MJ9   J3JW59   C5IB70   A0A182YPE1   A0A1Q3FNA4   A0A2C9GTY9   N6TW63   B0WFK6   A0A1Q3FPS2   C5IBF3   C5IB77   U4TXR1   A0A1Y9GKU7   A0A182WCM2   A0A182TKI7   Q16TM1   A0A023EM39  

EC Number

3.4.21.4

Pubmed

19121390    22432944    26354079    22118469    26227816    26483478    + More
17510324    21569254    7498434    12364791    28196534    20966253    8335004    25338147    19204376    24438588    30018880    20920257    23761445    20075255    15632085    17994087    22516182    25244985    23537049    24945155   

EMBL

BABH01001457    BABH01001458    ODYU01009503    SOQ53993.1    BABH01001460    BABH01001461    + More
NWSH01000168    PCG78826.1    JN315766    AFK64830.1    RSAL01000017    RVE52910.1    KQ459606    KPI91088.1    LADJ01066212    KPJ21686.1    AGBW02003040    OWR55583.1    JTDY01004566    KOB68004.1    KQ461198    KPJ06079.1    KPI91087.1    KPI91089.1    KPJ21685.1    AGBW02011879    OWR45991.1    BABH01036516    ODYU01012498    SOQ58840.1    JXUM01008849    KQ560270    KXJ83415.1    AY752851    AAV84264.1    APCN01000798    CH477774    EAT36354.1    EZ933290    ADJ57671.1    Z22930    AAAB01008964    KV878981    OJJ97808.1    AY752849    AAV84262.1    Z18890    KZ825476    PYI34337.1    Z18889    AAAB01008966    JQGA01001183    KGO68710.1    EAA13086.4    FJ839225    ACR61236.1    ATLV01018235    ATLV01018236    KE525226    KFB42849.1    DS232607    EDS43980.1    FJ839309    ACR61290.1    KPI91053.1    FJ839310    ACR61291.1    KFB42848.1    FJ839308    FJ839341    ACR61289.1    ACR61322.1    DS231852    EDS37676.1    PVWQ01000001    RDW92774.1    FJ839226    ACR61237.1    FJ839345    ACR61326.1    ADMH02001669    ETN61483.1    KFB42847.1    KZ825103    PYI24068.1    JX915894    AFZ78860.1    FJ839224    ACR61235.1    FJ839239    FJ839240    FJ839241    FJ839242    FJ839244    FJ839245    ACR61250.1    ACR61251.1    ACR61252.1    ACR61253.1    ACR61255.1    ACR61256.1    FJ839228    FJ839231    ACR61239.1    ACR61242.1    KQ460205    KPJ17099.1    FJ839232    FJ839233    FJ839234    FJ839235    FJ839236    FJ839238    ACR61243.1    ACR61244.1    ACR61245.1    ACR61246.1    ACR61247.1    ACR61249.1    FJ839338    ACR61319.1    KZ288316    PBC28310.1    CH379060    EAL33694.2    BT127477    AEE62439.1    FJ839230    ACR61241.1    GFDL01006008    JAV29037.1    APGK01052535    KB741213    ENN72611.1    DS231918    EDS26274.1    GFDL01005572    JAV29473.1    FJ839343    ACR61324.1    FJ839237    ACR61248.1    KB631625    ERL84793.1    CH477645    EAT37856.1    GAPW01003247    JAC10351.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000053240    UP000007151    + More
UP000037510    UP000069940    UP000249989    UP000075840    UP000008820    UP000007062    UP000075903    UP000075902    UP000076407    UP000075881    UP000184546    UP000075882    UP000248817    UP000075885    UP000030104    UP000030765    UP000002320    UP000256690    UP000000673    UP000002358    UP000249829    UP000069272    UP000242457    UP000075901    UP000001819    UP000076408    UP000019118    UP000030742    UP000075920   

PRIDE

H9IUB1    H9JW07    P35036    P35035    P35041   

Pfam

PF00089   Trypsin

Interpro

IPR001254   Trypsin_dom        + More
IPR018114   TRYPSIN_HIS       
IPR009003   Peptidase_S1_PA       
IPR001314   Peptidase_S1A       
IPR012224   Pept_S1A_FX       
IPR033116   TRYPSIN_SER       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9IUB1   A0A2H1WLN2   H9IUB0   A0A2A4K471   I3UIJ2   A0A3S2LFV6   + More
A0A194PDK1   A0A0N1PJX5   A0A212FPE2   A0A0L7KY81   A0A194QL10   A0A194PCY4   A0A194PEH2   A0A0N1IQS6   A0A212EWZ2   H9JW07   A0A2H1X0F7   A0A182GAC9   Q5QBG0   A0A1Y9GLX5   Q16PR8   F4MI42   P35037   A0A1S4GXU9   A0A182V8D5   A0A182TJQ8   A0A182U9U3   A0A1Y9J184   A0A182KHH7   A0A1L9WNS2   Q5QBG2   A0A182VGJ0   A0A2C9GTQ1   P35036   A0A1Y9GKV0   A0A1Y9J0J4   A0A2V5J8A4   A0A1Y9J180   P35035   A0A240PM69   A0A1S4H7M9   A0A0A2KWH5   Q7Q344   A0A182UPH4   A0A182LPG3   A0A340TBF8   C5IB65   A0A084VY05   B0XB10   C5IBB9   A0A194PDG5   A0A182UGL3   A0A182U4C7   C5IBC0   A0A084VY04   C5IBB8   B0W771   A0A182XL71   A0A3D8T2K0   C5IB66   P35041   C5IBF5   W5JDQ9   K7J8G2   A0A182ICF6   A0A084VY03   A0A2V5HHZ2   L0ATN6   A0A182FPP1   C5IB64   C5IB79   A0A2C9GTS0   C5IB68   A0A194RI37   A0A182V8R1   C5IB72   C5IBE8   A0A2A3E9B5   A0A182T724   A0A240PL37   Q29MJ9   J3JW59   C5IB70   A0A182YPE1   A0A1Q3FNA4   A0A2C9GTY9   N6TW63   B0WFK6   A0A1Q3FPS2   C5IBF3   C5IB77   U4TXR1   A0A1Y9GKU7   A0A182WCM2   A0A182TKI7   Q16TM1   A0A023EM39  

PDB

5CE1     E-value=4.36192e-15,     Score=193

KEGG

101746664    K09640 transmembrane protease serine 9 [EC:3.4.21.-] | (RefSeq) transmembrane protease serine 9-like

GO

GO:0004252   GO:0007596   GO:0005509   GO:0016021   GO:0005576   GO:0007586   GO:0008236   GO:0006508   GO:0033177   GO:0033179   GO:0015450   GO:0005737   GO:0005488   GO:0022891   GO:0003707   GO:0051537  

Subcellular location

Secreted  

Length:

172

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.11787

Exp number, first 60 AAs:

0.01349

Total prob of N-in:

0.19332

outside

1  -  172

 

 

Pi

230.513823

Theta

186.830722

Tajima's D

0.756583

CLR

0

CSRT

0.590970451477426

Interpretation

Uncertain