Gene

KWMTBOMO07617  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA001303

Annotation

PREDICTED:_tumor_suppressor_candidate_3_[Amyelois_transitella]

Location

Bomo_Chr13(-):1792431-1796499      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.506

CDS

ATGAATTTCAAAGTATTATTGTTACTAACAATAACTATAACATACTATGAAGGAGCTGCGCAACCTCGAGCTAAAGGGATTGAGGAGAAAGTGCAGCAGTTGACTGATATTACAGCAAAGAAGTCTGTAATTCCATTAAACATAAATAAGTTTAAGGAATATGTGAAGTCTCCTCCAAGGGATTATTCATTTGTAGTGATGTTCACTGCAATGGCACCTGCAAGAAGGTGTGCTATCTGTCAGCATGTTAACGATGAATATTTGTTGGTGGCCAACTCATTTAGATTCTCAGCTGCTTACAATAATAAATTATTCTTTGGTATTGTTGATTTTGATGAAGGCTCAGATATCTTCCAAATGTTACGGCTTAATACTGCACCTGTGATAATGCACTTCCCAGCTAAAGGCAAACCTAAGCCTGCTGACACAATGGACTTTGAGAGAGCTGGCATCCATGCTGAGGCCATCGCTAAGTGGATACAGGACAGAACTGATGTACAGATTCGAGTCTTCCGATCACCAAATTACTCAGCGGCTGTAGCTTTTTCAACTCTCTTCATCATATTGGCTGGTTTTCTTTATATCCGTAGAAACAACCTCGAGTTCCTCTACAATAAACAGTTATGGGCAGTTTGTGCTGTGTTCTTCTGCTTTGCAATGGTGTCTGGGCAGATGTGGAATCAAATTAGAGGCCCACCATTTTTCCATAGAACAAAAACTGGCCCGGTCTATATAAACGGGGGATCACACGGACAGTTTGTATTGGAGAGTTACATTGTTGCTATACTGAATGGGGCTGTGGTTGTGGGTATGATCCTAATGATTGAAGCAGCAGGTGGAGTTAAAAACCATGACCCAACACGAACCCTGGCCGAAGGGAAGCGTCGAAGGTTCCAGTCAGTTGTTGGTCTAATATTAGTCTGCGTGTTCTTCTCACTGCTTTTATCAGTATTCAGAGCAAAGACGCAAGGATATCCATATAGTTTCTTGTTCAAGTGA

Protein

MNFKVLLLLTITITYYEGAAQPRAKGIEEKVQQLTDITAKKSVIPLNINKFKEYVKSPPRDYSFVVMFTAMAPARRCAICQHVNDEYLLVANSFRFSAAYNNKLFFGIVDFDEGSDIFQMLRLNTAPVIMHFPAKGKPKPADTMDFERAGIHAEAIAKWIQDRTDVQIRVFRSPNYSAAVAFSTLFIILAGFLYIRRNNLEFLYNKQLWAVCAVFFCFAMVSGQMWNQIRGPPFFHRTKTGPVYINGGSHGQFVLESYIVAILNGAVVVGMILMIEAAGGVKNHDPTRTLAEGKRRRFQSVVGLILVCVFFSLLLSVFRAKTQGYPYSFLFK

Similarity

Belongs to the insulin family.

Uniprot

H9IVM3   A0A3S2NJZ2   A0A2H1VD56   A0A2A4K4Y6   S4PKA2   I4DK11   + More
A0A1E1W163   I4DMH9   A0A194QKH9   A0A194PDJ6   A0A212F2X0   R4WSD0   D2A0T6   A0A023F8X0   A0A170XZ91   A0A224XS00   A0A1B6FPH7   A0A1B6K7G7   A0A2J7R8G9   A0A1B6KAI8   A0A0V0G2T5   A0A2P8YXN4   A0A182Y680   R4G4I3   A0A182W8P5   A0A182RWP2   A0A182NP04   U5ERS3   A0A0T6AU61   A0A182K1N5   A0A182X2G1   A0A182VH14   A0A182PVR2   Q7PMF2   A0A182HR72   Q179Z6   A0A0A9W715   A0A1B0CM87   Q1HRR4   A0A1L8DTN5   K7J126   A0A2M4BT50   A0A2M4A5N8   W5JGB6   A0A2M3ZEY0   A0A2M3Z0Z6   T1DU17   A0A2M4A5I5   A0A1Y1MRH2   A0A2M4CTQ5   A0A182J8L4   A0A182MDR5   A0A0C9QLB5   A0A2M4CFQ7   A0A0M3QTH1   A0A088AT27   A0A182TIU8   E2C774   A0A158P2D2   A0A1S3DR32   A0A182KZ67   A0A023EPV7   A0A026WE28   A0A2A3EG61   B0WEC9   A0A1Q3FBV3   A0A336M6Y7   E9IEY8   Q8SY53   B4Q6P9   B4HYI1   A0A232FNB6   B4MTJ2   W8CAX0   B3N736   A0A034V1T9   A0A0K8TZJ0   A0A0A1X2D3   Q29MN1   B4G903   A0A3B0K8F3   A0A1W4V7V4   B4KJM7   A0A151WTL0   B4NWV7   A0A182F357   E2AY50   B3MPG6   F4WUP4   B4LSH5   A0A0P6GR00   A0A195E505   A0A1J1HLU4   A0A195BTB2   A0A182GRF3   E9GTV6   F8TGY1   A0A1L8EH06   A0A336MBG5   D3TMZ0  

Pubmed

19121390    23622113    22651552    26354079    22118469    23691247    + More
18362917    19820115    25474469    29403074    25244985    12364791    17510324    25401762    26823975    17204158    20075255    20920257    23761445    28004739    20798317    21347285    20966253    24945155    24508170    21282665    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17994087    22936249    28648823    24495485    25348373    25830018    15632085    17550304    18057021    21719571    26483478    21292972    21668550    20353571   

EMBL

BABH01001468    BABH01001469    BABH01001470    BABH01001471    RSAL01000017    RVE52906.1    + More
ODYU01001899    SOQ38755.1    NWSH01000168    PCG78833.1    GAIX01004615    JAA87945.1    AK401629    BAM18251.1    GDQN01010314    JAT80740.1    AK402497    BAM19119.1    KQ461198    KPJ06073.1    KQ459606    KPI91083.1    AGBW02010668    OWR48077.1    AK417607    BAN20822.1    KQ971338    EFA01636.1    GBBI01000835    JAC17877.1    GEMB01003868    JAR99386.1    GFTR01005114    JAW11312.1    GECZ01017663    JAS52106.1    GECU01000331    JAT07376.1    NEVH01006721    PNF37128.1    GEBQ01031519    JAT08458.1    GECL01003695    JAP02429.1    PYGN01000298    PSN49006.1    ACPB03019965    GAHY01001335    JAA76175.1    GANO01002689    JAB57182.1    LJIG01022810    KRT78601.1    AAAB01008980    EAA13927.5    APCN01001654    CH477342    EAT43075.1    GBHO01040403    GDHC01006388    JAG03201.1    JAQ12241.1    AJWK01018369    DQ440030    ABF18063.1    GFDF01004261    JAV09823.1    GGFJ01007125    MBW56266.1    GGFK01002740    MBW36061.1    ADMH02001597    ETN61920.1    GGFM01006312    MBW27063.1    GGFM01001451    MBW22202.1    GAMD01000559    JAB01032.1    GGFK01002746    MBW36067.1    GEZM01023579    JAV88293.1    GGFL01004558    MBW68736.1    AXCM01000350    GBYB01001394    GBYB01001397    JAG71161.1    JAG71164.1    GGFL01000002    MBW64180.1    CP012523    ALC38903.1    GL453340    EFN76187.1    ADTU01007116    GAPW01002543    JAC11055.1    KK107250    EZA54360.1    KZ288254    PBC30763.1    DS231907    EDS45489.1    GFDL01009984    JAV25061.1    UFQT01000478    SSX24649.1    GL762730    EFZ20865.1    AE014134    AY075331    AAF52636.2    AAL68198.1    CM000361    CM002910    EDX04208.1    KMY89034.1    CH480818    EDW52111.1    NNAY01000009    OXU32073.1    CH963852    EDW75431.1    GAMC01005341    GAMC01005339    JAC01215.1    CH954177    EDV59332.1    GAKP01023430    JAC35528.1    GDHF01032626    GDHF01009869    JAI19688.1    JAI42445.1    GBXI01008783    JAD05509.1    CH379060    EAL33662.1    CH479180    EDW28833.1    OUUW01000004    SPP79808.1    CH933807    EDW11472.1    KQ982753    KYQ51174.1    CM000157    EDW88487.1    GL443762    EFN61646.1    CH902620    EDV31262.1    KPU73288.1    GL888375    EGI62041.1    CH940649    EDW64797.1    GDIP01117145    GDIQ01029894    GDIQ01002793    LRGB01002384    JAL86569.1    JAN64843.1    KZS07981.1    KQ979657    KYN19982.1    CVRI01000008    CRK88514.1    KQ976408    KYM91176.1    JXUM01016218    KQ560452    KXJ82352.1    GL732565    EFX77074.1    HQ896857    HQ896858    AEI98820.1    GFDG01000802    JAV17997.1    UFQT01000091    UFQT01000704    SSX19570.1    SSX26671.1    CCAG010021443    EZ422792    ADD19068.1   

Proteomes

UP000005204    UP000283053    UP000218220    UP000053240    UP000053268    UP000007151    + More
UP000007266    UP000235965    UP000245037    UP000076408    UP000015103    UP000075920    UP000075900    UP000075884    UP000075881    UP000076407    UP000075903    UP000075885    UP000007062    UP000075840    UP000008820    UP000092461    UP000002358    UP000000673    UP000075880    UP000075883    UP000092553    UP000005203    UP000075902    UP000008237    UP000005205    UP000079169    UP000075882    UP000053097    UP000242457    UP000002320    UP000000803    UP000000304    UP000001292    UP000215335    UP000007798    UP000008711    UP000001819    UP000008744    UP000268350    UP000192221    UP000009192    UP000075809    UP000002282    UP000069272    UP000000311    UP000007801    UP000007755    UP000008792    UP000076858    UP000078492    UP000183832    UP000078540    UP000069940    UP000249989    UP000000305    UP000092444   

PRIDE

H9IVM3    Q8SY53   

Pfam

PF04756   OST3_OST6        + More
PF00049   Insulin
PF01875   Memo

Interpro

IPR036249   Thioredoxin-like_sf        + More
IPR021149   OligosaccharylTrfase_OST3/OST6       
IPR036438   Insulin-like_sf       
IPR022353   Insulin_CS       
IPR016179   Insulin-like       
IPR022352   Insulin_family       
IPR002737   MEMO1_fam       

SUPFAM

SSF52833   SSF52833        + More
SSF56994   SSF56994       

CDD

cd07361  MEMO_like

ProteinModelPortal

H9IVM3   A0A3S2NJZ2   A0A2H1VD56   A0A2A4K4Y6   S4PKA2   I4DK11   + More
A0A1E1W163   I4DMH9   A0A194QKH9   A0A194PDJ6   A0A212F2X0   R4WSD0   D2A0T6   A0A023F8X0   A0A170XZ91   A0A224XS00   A0A1B6FPH7   A0A1B6K7G7   A0A2J7R8G9   A0A1B6KAI8   A0A0V0G2T5   A0A2P8YXN4   A0A182Y680   R4G4I3   A0A182W8P5   A0A182RWP2   A0A182NP04   U5ERS3   A0A0T6AU61   A0A182K1N5   A0A182X2G1   A0A182VH14   A0A182PVR2   Q7PMF2   A0A182HR72   Q179Z6   A0A0A9W715   A0A1B0CM87   Q1HRR4   A0A1L8DTN5   K7J126   A0A2M4BT50   A0A2M4A5N8   W5JGB6   A0A2M3ZEY0   A0A2M3Z0Z6   T1DU17   A0A2M4A5I5   A0A1Y1MRH2   A0A2M4CTQ5   A0A182J8L4   A0A182MDR5   A0A0C9QLB5   A0A2M4CFQ7   A0A0M3QTH1   A0A088AT27   A0A182TIU8   E2C774   A0A158P2D2   A0A1S3DR32   A0A182KZ67   A0A023EPV7   A0A026WE28   A0A2A3EG61   B0WEC9   A0A1Q3FBV3   A0A336M6Y7   E9IEY8   Q8SY53   B4Q6P9   B4HYI1   A0A232FNB6   B4MTJ2   W8CAX0   B3N736   A0A034V1T9   A0A0K8TZJ0   A0A0A1X2D3   Q29MN1   B4G903   A0A3B0K8F3   A0A1W4V7V4   B4KJM7   A0A151WTL0   B4NWV7   A0A182F357   E2AY50   B3MPG6   F4WUP4   B4LSH5   A0A0P6GR00   A0A195E505   A0A1J1HLU4   A0A195BTB2   A0A182GRF3   E9GTV6   F8TGY1   A0A1L8EH06   A0A336MBG5   D3TMZ0  

PDB

4M90     E-value=3.52378e-49,     Score=491

KEGG

101747213    K12669 oligosaccharyltransferase complex subunit gamma | (RefSeq) tumor suppressor candidate 3

PATHWAY

00510    N-Glycan biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04141    Protein processing in endoplasmic reticulum - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0005576   GO:0005179   GO:0008250   GO:0018279   GO:0016740   GO:0005737   GO:0012505   GO:0035010   GO:0016477   GO:0016757   GO:1903830  

PANTHER

PTHR12692   PTHR11060  

Subcellular location

Secreted  

SignalP

Position:   1 - 20,         Likelihood:  0.903454

 

 

Length:

332

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

83.45755

Exp number, first 60 AAs:

0.10425

Total prob of N-in:

0.00659

outside

1  -  175

TMhelix

176  -  195

inside

196  -  207

TMhelix

208  -  226

outside

227  -  257

TMhelix

258  -  280

inside

281  -  300

TMhelix

301  -  320

outside

321  -  332

 

 

Pi

20.933183

Theta

28.200749

Tajima's D

-1.154683

CLR

117.541804

CSRT

0.108644567771611

Interpretation

Uncertain