Silkworm Genome Informatics Database

Gene

KWMTBOMO07589 Validated by peptides from experiments

Pre Gene Modal

BGIBMGA013717

Annotation

COP_complex_beta_subunit_[Bombyx_mori]

Location

Bomo_Chr13(-):969363-979341 View in EpiBrowser

Full name

Coatomer subunit beta

Alternative Name

Beta-coat protein

Location in the cell

Cytoplasmic Reliability : 1.258 Golgi Reliability : 1.36

CDS

ATGGCGGTTGTGGAGCAGCCATGCTATACTCTTATCAATTTTCCAACTGATTTAGAACCATGCAATGAGATGCAACTTAAACTTGATCTTGAGAAAGGTGATACAAAAAAGAAAATAGAAGCATTAAAAAAGACAATAGGAATAATACTTTCTGGGGAAAAGATACCAGGTCTGCTCATGATCATTATTAGGTTCGTGTTGCCATTGCAAGATCACATGATCAAGAAGCTGCTACTTATCTTTTGGGAGATTGTACCAAAGACCTCACCTGATGGAAAATTATTGCAGGAAATGATCCTTGTCTGTGATGCCTATAGAAAGGATCTTCAACATCCAAATGAGTTCATTCGCGGATCTACTCTGCGTTTTCTGTGCAAGCTGAAAGAGCCTGAACTCCTTGAACCCCTAATGCCAGCCATACGGTCCTGTCTCGAGCACAGACATTCGTATGTCAGGAGGAATGCTGTTCTTGCTATTTTTACCATATATAGGAACTTTGAATTCCTAATTCCTGATGCACCGGAGCTGGTAGCAAACTTCCTGGAGACTGAGCAAGACATGTCTTGCAAGCGTAATGCCTTCCTCATGCTGCTGCATGCTGACCAAGAGCGTGCTTTGACATATTTGTCTTCTAGGCTCGATAATGTACACAGCTTTGGAGATATTCTTCAATTGGTCATAGTCGAGTTGATTTATAAGGTCTGCCACACGAACCCGTCGGAGCGCTCCCGGTTCATCCGCACCGTGTACGGGCTGCTCAACGCCAGCAGCGCCGCCGTCCGGTACGAGGCCGCCGGCACGCTCGTCACCCTCTCCAACGCGCCCGCCGCCATCAAGGCGGCGGCGGCGTGCTACATCGACCTCGTGGTGAAGGAGAGCGACAACAACGTGAAGCTGATTGTCGTGGGGCGGCTGGGAGCCCTGCGCGCCGAGGGCGGGGAGGGGGCCGCGCGCGCCCTGCCCGACCTGGCCATGGACGTGCTGCGCGTGCTCGCCTCCTCCGACCTCGACGTCAGGAAGCACACGCTGCAGCTCGCGCTGGAGCTGGTGAGCGCGCGGCACGCGGAGGAGCTGGTGCAGGTGCTGCGCAAGGAGGCGGCGCGGGCGCACTCCGCCGACCACGACGACGCCGCCAAGTACCGCCAGCTGCTCGTGCGCGCCATGCACAAGGCCGCGCTCAAGTTCCCGGAGGTGGCTGGCAGCGTGGCGCCGGCGCTGCTGGAGCTGCTGGGCGAGGGCAGCGAGGCGGCGGCGCACGACGTGCTGCTGTTCCTGCGCCACGCGCTGCACGCCTTCCCCGACCTCAGGGACCACATCTACCAGACAGCACACACTACAGCGCGCCTCGTGTCGCAGAAACTGGTGGAGTCCGTGCGCAGCGTGCGCGTGGGCAGGCCGGCCCGCGCCGCGCTGTGGCTGCTCGCGCAGTTCGCCGACACGCCGGGCCGCGCGCGCGCCGCGCTGCACGTGCTCGCCGACGTCATCGAGGGCGCCGCCGACACGCAGCAGCCGGAGAGCGGGCCGGCCGCGGCGCCGCGCCGCCTCGTCACCAGCGACGGCACCTACGCCACGCAGTCCGCCTTCAACCTGCCCGCGTCGGGTGCGGCGGAGGGCGGCGCGGCGGAGGGCGGTGCGAGACTGGGCGGCGCACTGCTGGAGGGCGAGAGCTTCACGGCGGTGTGCGCGTGCTCGGCGCTGGCCAAGCTGGCCCTGAAGCTGCCGCGGCAGGAGGCGGCCCGCGCGCTGCACCTGGCCGCCGTCCTGCTGGCGCGCCACAAGCAGAACGCAGGGCAGCGCGGCGGGCTGACGGCGGACGACATGGAGCACGCGGCGCTGTGCGTGCAGGCGGGGCTGGCGGGCGCGGGGCTGGGGGGCGGGGCGGGCGGCGCGGACGTGCGGCGCGCGCTGCTGGACGCGTCGGACGCGGCGCTGGCGGCGCTGCTGGCGCTCCCGGACCGCGAGCCGCACCTGCTGGAGGACGTCGACAAGGAGCGTGAACCGAAACGGCAGGAGCAGAAGGTGGAGATCGAGACGGGCATCACGTTCTCGCAGCTGGCCGGCGCCGGCGCCTCCGGCTCGCAGCACGACATGTTCGAGCTGGCGCTCAACAAGGCGCTGCAAGGTCGCAGCGGTGGCGAGGCAATCGACCGCGGCAAGTTGTGCCGCGTGCGCCAGTTGACAGGATGTTCCGACCCCGTGTACGCGGAAGCCATCGTCTCCGTCAACCAGTACGACATCGTGCTGGACGTGCTGCTCGTCAACCAGACCGACGACACGCTGCAGAACTGCTGCGTGGAGCTGGCCACGCTGGGCGAGCTGCGCCTGGTGGAGCGCGCGGCCGAGGTGGTGCTGGCGCCGCGGGACTTCGCCTCGCTGCGGGCGCACGTCAAGGTCGCCTCCACGGAGAATGGCGTCATCTTCGGGAACGTGGTATACGAAGTGACGGGAGCGTCCATGGACCGCGGCGTGGTCGTGCTGAATGACATCCACATTGACATTGTCGACTTCATCCAGCCGGCGCACTGCAGCGACGCCGACTTCAGGCAAATGTGGGCTGAATTCGAATGGGAGAACAAGGTCTCCGTGAACACCAACATGACGGACTTGCACGAGTACCTGCAGCATCTGCTCGCCTCCACCAACATGAAGTGCCTGACCCCCGAGAAGGCGCTGTCGGGGCAGTGCGGGTTCATGGCGGCCAACCTATACGCGCGGTCCATCTTCGGCGAGGACGCGCTCGCCAACCTCAGTATCGAGCGGCCGCTGCACAAGCCCGGCGCGCCCGTGCTCGGACACGTGCGCATCCGGGCCAAGACACAGGGCATGGCGCTGAGTCTGGGCGACAAGATCAACATGATGCAGAAGGCTTCCCACCAGAAGCCCGCGGACCCCACGCCGGCCGCCTGA

Protein

MAVVEQPCYTLINFPTDLEPCNEMQLKLDLEKGDTKKKIEALKKTIGIILSGEKIPGLLMIIIRFVLPLQDHMIKKLLLIFWEIVPKTSPDGKLLQEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEPELLEPLMPAIRSCLEHRHSYVRRNAVLAIFTIYRNFEFLIPDAPELVANFLETEQDMSCKRNAFLMLLHADQERALTYLSSRLDNVHSFGDILQLVIVELIYKVCHTNPSERSRFIRTVYGLLNASSAAVRYEAAGTLVTLSNAPAAIKAAAACYIDLVVKESDNNVKLIVVGRLGALRAEGGEGAARALPDLAMDVLRVLASSDLDVRKHTLQLALELVSARHAEELVQVLRKEAARAHSADHDDAAKYRQLLVRAMHKAALKFPEVAGSVAPALLELLGEGSEAAAHDVLLFLRHALHAFPDLRDHIYQTAHTTARLVSQKLVESVRSVRVGRPARAALWLLAQFADTPGRARAALHVLADVIEGAADTQQPESGPAAAPRRLVTSDGTYATQSAFNLPASGAAEGGAAEGGARLGGALLEGESFTAVCACSALAKLALKLPRQEAARALHLAAVLLARHKQNAGQRGGLTADDMEHAALCVQAGLAGAGLGGGAGGADVRRALLDASDAALAALLALPDREPHLLEDVDKEREPKRQEQKVEIETGITFSQLAGAGASGSQHDMFELALNKALQGRSGGEAIDRGKLCRVRQLTGCSDPVYAEAIVSVNQYDIVLDVLLVNQTDDTLQNCCVELATLGELRLVERAAEVVLAPRDFASLRAHVKVASTENGVIFGNVVYEVTGASMDRGVVVLNDIHIDIVDFIQPAHCSDADFRQMWAEFEWENKVSVNTNMTDLHEYLQHLLASTNMKCLTPEKALSGQCGFMAANLYARSIFGEDALANLSIERPLHKPGAPVLGHVRIRAKTQGMALSLGDKINMMQKASHQKPADPTPAA

Description

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Subunit

Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.

Uniprot

A0A023SG69 A0A2A4JRY4 A0A194PCP2 A0A194RM94 N6UJZ2 A0A2R5LHR0 + More
A0A1W7RAR9 A0A1A8IKP0 W5U788 A0A1A8SJH4 A0A1A8PSP3 T1JB85 A0A1A8DEZ0 A0A1A8U1N2

Pubmed

26354079 23537049 23127152

EMBL

KJ574013 AHX71939.1 NWSH01000725 PCG74579.1 KQ459606 KPI91061.1 + More
KQ460205 KPJ17106.1 APGK01017098 KB739995 ENN82045.1 GGLE01004947 MBY09073.1 GFAH01000156 JAV48233.1 HAED01011465 HAEE01015260 SBQ97807.1 JT406074 AHH37439.1 HAEH01012341 HAEI01016022 SBS18491.1 HAEF01014960 HAEG01009247 SBR84009.1 JH432010 HADZ01017732 HAEA01003376 SBQ31856.1 HADY01022795 HAEJ01001752 SBS42209.1

Proteomes

UP000218220 UP000053268 UP000053240 UP000019118 UP000221080

Pfam

PF07718   Coatamer_beta_C        + More
PF01602   Adaptin_N
PF14806   Coatomer_b_Cpla

Interpro

IPR016024   ARM-type_fold        + More
IPR016460   COPB1
IPR002553   Clathrin/coatomer_adapt-like_N
IPR029446   COPB1_appendage_platform_dom
IPR011710   Coatomer_bsu_C
IPR011989   ARM-like

SUPFAM

SSF48371 SSF48371

Gene 3D

1.25.10.10

ProteinModelPortal

A0A023SG69 A0A2A4JRY4 A0A194PCP2 A0A194RM94 N6UJZ2 A0A2R5LHR0 + More
A0A1W7RAR9 A0A1A8IKP0 W5U788 A0A1A8SJH4 A0A1A8PSP3 T1JB85 A0A1A8DEZ0 A0A1A8U1N2

PDB

5NZV E-value=8.57896e-161, Score=1458

KEGG

100379188 K17301 coatomer subunit beta | (RefSeq) COPB, beta-COP; coatomer protein complex subunit beta

GO

GO:0016192 GO:0005198 GO:0030126 GO:0000139 GO:0006886 GO:0061053 GO:0030903 GO:0030117 GO:0005737 GO:0005488 GO:0022891 GO:0003707 GO:0051537

PANTHER

PTHR10635

Subcellular location

Cytoplasm
Golgi apparatus membrane
Cytoplasmic vesicle
COPI-coated vesicle membrane

Length:

968

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

18.99941

Exp number, first 60 AAs:

12.7661

Total prob of N-in:

0.83611

POSSIBLE N-term signal

sequence

inside

1 - 45

TMhelix

46 - 68

outside

69 - 968

Pi

228.638455

Theta

165.849046

Tajima's D

0.346198

CLR

0.248819

CSRT

0.474426278686066

Interpretation

Uncertain

Source	Sequence	Identity	Evalue
31250652	GSSAVAIVNSAYIDFK	100.00	6e-04
28556443	ALPDLAMDVLR	100.00	0.005

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics