Gene

KWMTBOMO07565  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005854

Annotation

PREDICTED:_protein_turtle_[Bombyx_mori]

Location

Bomo_Chr12(+):17509447-17519105      View in EpiBrowser

Full name

Protein borderless      

Location in the cell

PlasmaMembrane   Reliability : 0.997

CDS

ATGCGAGTACAGCTAGTGCCCGCCGCACTGGCGCTGATGGCGAGCGGCGCCGTGCTGTGGCCGCCGAGCCGCGCCTCGCTGCTGCCGCTCGACGCAGAGCACCTGCACGCCTCCGTCGGCGGGTACGCCGTCATGAACTGCCATCTCGACTTCCCCTTCGGACACGAAATCCCCTATCGACTCCAGTGGGACAAGGATGGAGAGACGATATTCTCGTGGTACAGCACGGAGGGTAGTGCGCAGACTGCGGACCGGTGGGGCGGGCGCGTGCGTCGCGTGGACGGGGAGGTGCTCGGCCTCGGGCGCGGCTCCATCAACGTGACGGCCGTGCGCGAGACCGACGCCGGCCTCTACCGCTGTCTCGTCCTCTTCCCCAACCGCACCCCGCCCGCGCGCAACAACGGGACCTACTACCGCCTCGAGGTGGACGGTGGGAACCTGATAGTCACGCCGCCCATGAACGTCACGGTGCTGGAGACCGAGCGCGCCGAGCTCGAGTGCCTACCCAAGGACCCGCAGTCGGCGGTCGAGTGGTACAGGCAGGGTGCCCTGCTGAACCAGCTGCCGGAGCTCGCGGCGCGCTCCGAGGTTGCTGCTAACGGCAGTCTCGTGGTGCGCGTCACGACCAGCTCCGATCCTGGCGAGTACGAGTGTCGTGTGAGCTCTCCCGACGGTCACATCCAAAGCGCCAGCGCCTTCCTCGATGTCCACTACAAAGCCAAAGTAGTGTACTCACCGAAGGAACGGCATTTCCCGTTCGGCAAGCCGGCCAGTCTCGACTGCCACTTCAGTGCCAACCCTCCTTTGACGAACTTGCGCTGGGAAAAAGATGGATTTCTGTTCGATCCCTATAACGTCCAAGGTGTGTTCTACAGCAGGAATGGTAGTCTGCTCTTCAACCAAGTGGACGAGACGCACGAGGGCGTGTACTCGTGCACTCCGTACAACGCGCTGGGCACGGAGGGCCCGTCCGCGGGCGTGAGGGTGCGCGTGCAACGACCGCCGGCGTTTGCCGCACGCCCTCTGCCCCTCTACGTGGCGCGCCTCGGGGCCACGCTCTCGCTGCCCTGCAAGGTGGCGGTCTATCAACACAACGACCCTCCGCTCCTCCGCTGGACTAGAAAAGACGGTAGCTCCCTGCCCGACGGCCGGCACTCGGTGGACGAGGGCAACCTGACCGTGGTGGACGTGGCGGAGGAGGACCGCGGAGTCTACGTGTGCACCGTCAGCAACGAGGCCGCCTCCGTGAGCGTGGAGACCGAACTCCTCGTCGAGAACGTGCCTCCTCGGGCCCCGTACAACCTAACCGCAGCGCCGTCCAACGACTCCATACATCTCACCTGGGTGCCCGGCCACAACGGTCTCGACGTCGACTACAACGTGTGGTACCGCGAGCGCACCGTCAGCGAGTGGCGCACCATGAAGATACTGACGCGGGGGCTGACCGAGGCGACGCTCGTCGGACTGCGCCCCGCCACCGAGTACGAGCTGCGGGTGCTCTCCCAGGACCTCATCGGAGACGGGCTCTTCAGCAAACCGATCTTCGTGCGAACCTTTGGCTCCGAATTCAACGAAAAGTCCGAGTACGCTCCAGTGGCGGCCGTCACCGAGAGCTCGGGCACAGTACCCCTCGAGGGAGAAGAGTTGGAGGTGTCGGTGCGACTGATCGACGAGGGGGCGCTGGTCCGCTGGGCGCGCGACGTGGAGGACGACACGGGCTGCACGCTGCGCTGGTACCTCGACCAGGGCGCGCCGCGACTGCTCGCCACGCTGCGCACCCACGAGGACTACGCGCTCGTGCGCGAGGTGGAGGAGGGCGCGCGGTACCGGGCGCGCGTGGAGTGCGCGAGCGGCGCGCGGGGCGGCGCGGGGCTGGCGGTGCCGCAGTACGCGCGGCTGCGGGGCGCGGCGCTGGGCTGCGCGGGCGGCGCCGTGCTGCTGGGGGCGGCGGCGCTGCTGCTGTACGCGTGCCGCCACCGCCTGTGCGCGCGCTGA

Protein

MRVQLVPAALALMASGAVLWPPSRASLLPLDAEHLHASVGGYAVMNCHLDFPFGHEIPYRLQWDKDGETIFSWYSTEGSAQTADRWGGRVRRVDGEVLGLGRGSINVTAVRETDAGLYRCLVLFPNRTPPARNNGTYYRLEVDGGNLIVTPPMNVTVLETERAELECLPKDPQSAVEWYRQGALLNQLPELAARSEVAANGSLVVRVTTSSDPGEYECRVSSPDGHIQSASAFLDVHYKAKVVYSPKERHFPFGKPASLDCHFSANPPLTNLRWEKDGFLFDPYNVQGVFYSRNGSLLFNQVDETHEGVYSCTPYNALGTEGPSAGVRVRVQRPPAFAARPLPLYVARLGATLSLPCKVAVYQHNDPPLLRWTRKDGSSLPDGRHSVDEGNLTVVDVAEEDRGVYVCTVSNEAASVSVETELLVENVPPRAPYNLTAAPSNDSIHLTWVPGHNGLDVDYNVWYRERTVSEWRTMKILTRGLTEATLVGLRPATEYELRVLSQDLIGDGLFSKPIFVRTFGSEFNEKSEYAPVAAVTESSGTVPLEGEELEVSVRLIDEGALVRWARDVEDDTGCTLRWYLDQGAPRLLATLRTHEDYALVREVEEGARYRARVECASGARGGAGLAVPQYARLRGAALGCAGGAVLLGAAALLLYACRHRLCAR

Description

In the developing eye, has a role in axonal targeting of the R7 photoreceptor where it functions together with tutl. Probably mediates homotypic cell adhesion; the effect is inhibited by Lar.

Subunit

Interacts with tutl.

Similarity

Belongs to the immunoglobulin superfamily.

Keywords

Cell adhesion   Cell membrane   Cell projection   Complete proteome   Disulfide bond   Immunoglobulin domain   Membrane   Neurogenesis   Reference proteome   Repeat   Signal   Transmembrane   Transmembrane helix  

Feature

chain  Protein borderless

Uniprot

H9J8L2   A0A194PUD3   A0A212F6C3   A0A3S2NV47   A0A2W1BWY3   A0A0L7KWH6   + More
A0A0N1IP35   D2A0Y2   A0A139WJC8   A0A0T6B1W3   A0A088AN32   A0A154PS19   A0A026X5V7   K7J1P5   A0A2A3EHK7   F4W5E8   A0A232EMP2   A0A0L7RDX9   A0A3L8DVQ2   E2B0D7   E9ICY1   A0A158NYW2   A0A1B6C0S3   A0A195BTN9   A0A1B6C3G7   A0A1B6KD29   A0A151X339   A0A1B6J2U5   A0A195FT91   A0A0Q5WG78   B3N3Q5   A0A0L0BP23   B4MDD1   E2BT87   U4UK39   B4I375   B4NYI8   A0A0K8WJZ6   A0A034VQ66   B4KFQ3   Q9U4G1   A0A0J9QWH5   W8B3E9   E2B0D6   A0A1I8QFE5   Q29NN7   A0A3B0K274   A0A0Q9WV25   B4N0N7   A0A1Y1LJ10   A0A195D2D3   A0A1I8MKP2   A0A1W4V454   B4JD35   U5ETE2   A0A0A1WK23   T1PJJ1   A0A0R3NRR2   B3MLP1   A0A1B0FHR1   A0A067QVF2   A0A2J7PQ41   A0A182F506   A0A1Q3FQQ4   A0A1Q3FQS2   A0A1Q3FR48   A0A182UXV0   A0A182Y0F0   A0A1S4G2E4   A0A1L8DLS6   Q16G95   A0A1Q3FQN3   A0A1L8DM41   A0A182H1K2   A0A182WG88   Q7PWJ1   A0A182RM00   A0A1S4GZP9   A0A182LMQ0   A0A182JAV5   A0A1W4XW64   A0A182QLE2   A0A182NUS4   A0A084W1U3   A0A1Q3FR41   A0A1Q3FQW8   A0A1B0CSL7   A0A336M353   B0WCJ8   A0A0M4E3B9   A0A0M4E327   A0A182XNU3   A0A182I7E6   A0A182SBW7   A0A182K8T6   A0A182PU68  

Pubmed

19121390    26354079    22118469    28756777    26227816    18362917    + More
19820115    24508170    20075255    21719571    28648823    30249741    20798317    21282665    21347285    17994087    26108605    23537049    17550304    25348373    10731132    12537572    10731138    12537569    24174674    22936249    24495485    15632085    28004739    25315136    25830018    24845553    25244985    17510324    26483478    12364791    20966253    24438588   

EMBL

BABH01038609    BABH01038610    BABH01038611    BABH01038612    KQ459592    KPI96932.1    + More
AGBW02010072    OWR49259.1    RSAL01000164    RVE45303.1    KZ149931    PZC77320.1    JTDY01004919    KOB67593.1    KQ460642    KPJ13358.1    KQ971338    EFA02574.2    KYB28100.1    LJIG01016181    KRT81372.1    KQ435102    KZC14663.1    KK107013    EZA62874.1    KZ288245    PBC31200.1    GL887645    EGI70598.1    NNAY01003321    OXU19625.1    KQ414613    KOC69024.1    QOIP01000003    RLU24527.1    GL444507    EFN60856.1    GL762436    EFZ21560.1    ADTU01004299    GEDC01030429    JAS06869.1    KQ976407    KYM91439.1    GEDC01029364    JAS07934.1    GEBQ01030631    JAT09346.1    KQ982566    KYQ54803.1    GECU01034855    GECU01014202    JAS72851.1    JAS93504.1    KQ981276    KYN43641.1    CH954177    KQS70085.1    EDV57714.1    JRES01001684    KNC20964.1    CH940661    EDW71192.2    GL450384    EFN81089.1    KB632390    ERL94444.1    CH480820    EDW54220.1    CM000157    EDW87621.1    GDHF01019990    GDHF01000831    JAI32324.1    JAI51483.1    GAKP01014982    GAKP01014980    JAC43970.1    CH933807    EDW11018.1    AE014134    AF181644    BT071817    AY058245    AAD55430.1    AAL13474.1    ACN58580.1    CM002910    KMY88044.1    GAMC01014987    JAB91568.1    EFN60855.1    CH379059    EAL34181.3    OUUW01000004    SPP79101.1    KRF85521.1    CH963920    EDW77650.2    GEZM01054449    JAV73642.1    KQ977004    KYN06539.1    CH916368    EDW04279.1    GANO01004415    JAB55456.1    GBXI01015442    JAC98849.1    KA648098    AFP62727.1    KRT03732.1    CH902620    EDV30762.2    CCAG010004699    KK852904    KDR14027.1    NEVH01022640    PNF18458.1    GFDL01005128    JAV29917.1    GFDL01005108    JAV29937.1    GFDL01005047    JAV29998.1    GFDF01006661    JAV07423.1    CH478304    EAT33261.1    GFDL01005148    JAV29897.1    GFDF01006660    JAV07424.1    JXUM01103746    JXUM01103747    JXUM01103748    JXUM01103749    JXUM01103750    JXUM01103751    KQ564831    KXJ71679.1    AAAB01008984    EAA14786.3    AXCN02000740    ATLV01019458    KE525272    KFB44187.1    GFDL01005109    JAV29936.1    GFDL01005045    JAV30000.1    AJWK01026233    AJWK01026234    AJWK01026235    UFQT01000380    SSX23751.1    DS231888    EDS43569.1    CP012523    ALC38084.1    ALC37934.1    APCN01003388   

Proteomes

UP000005204    UP000053268    UP000007151    UP000283053    UP000037510    UP000053240    + More
UP000007266    UP000005203    UP000076502    UP000053097    UP000002358    UP000242457    UP000007755    UP000215335    UP000053825    UP000279307    UP000000311    UP000005205    UP000078540    UP000075809    UP000078541    UP000008711    UP000037069    UP000008792    UP000008237    UP000030742    UP000001292    UP000002282    UP000009192    UP000000803    UP000095300    UP000001819    UP000268350    UP000007798    UP000078542    UP000095301    UP000192221    UP000001070    UP000007801    UP000092444    UP000027135    UP000235965    UP000069272    UP000075903    UP000076408    UP000008820    UP000069940    UP000249989    UP000075920    UP000007062    UP000075900    UP000075882    UP000075880    UP000192223    UP000075886    UP000075884    UP000030765    UP000092461    UP000002320    UP000092553    UP000076407    UP000075840    UP000075901    UP000075881    UP000075885   

PRIDE

H9J8L2    Q9U4G1   

Pfam

PF00041   fn3        + More
PF00047   ig
PF07679   I-set
PF13895   Ig_2
PF07686   V-set

Interpro

IPR003598   Ig_sub2        + More
IPR036179   Ig-like_dom_sf       
IPR003961   FN3_dom       
IPR007110   Ig-like_dom       
IPR003599   Ig_sub       
IPR013783   Ig-like_fold       
IPR036116   FN3_sf       
IPR013151   Immunoglobulin       
IPR013098   Ig_I-set       
IPR013106   Ig_V-set       

SUPFAM

SSF49265   SSF49265        + More
SSF48726   SSF48726       

Gene 3D

2.60.40.10    

CDD

cd00063  FN3

ProteinModelPortal

H9J8L2   A0A194PUD3   A0A212F6C3   A0A3S2NV47   A0A2W1BWY3   A0A0L7KWH6   + More
A0A0N1IP35   D2A0Y2   A0A139WJC8   A0A0T6B1W3   A0A088AN32   A0A154PS19   A0A026X5V7   K7J1P5   A0A2A3EHK7   F4W5E8   A0A232EMP2   A0A0L7RDX9   A0A3L8DVQ2   E2B0D7   E9ICY1   A0A158NYW2   A0A1B6C0S3   A0A195BTN9   A0A1B6C3G7   A0A1B6KD29   A0A151X339   A0A1B6J2U5   A0A195FT91   A0A0Q5WG78   B3N3Q5   A0A0L0BP23   B4MDD1   E2BT87   U4UK39   B4I375   B4NYI8   A0A0K8WJZ6   A0A034VQ66   B4KFQ3   Q9U4G1   A0A0J9QWH5   W8B3E9   E2B0D6   A0A1I8QFE5   Q29NN7   A0A3B0K274   A0A0Q9WV25   B4N0N7   A0A1Y1LJ10   A0A195D2D3   A0A1I8MKP2   A0A1W4V454   B4JD35   U5ETE2   A0A0A1WK23   T1PJJ1   A0A0R3NRR2   B3MLP1   A0A1B0FHR1   A0A067QVF2   A0A2J7PQ41   A0A182F506   A0A1Q3FQQ4   A0A1Q3FQS2   A0A1Q3FR48   A0A182UXV0   A0A182Y0F0   A0A1S4G2E4   A0A1L8DLS6   Q16G95   A0A1Q3FQN3   A0A1L8DM41   A0A182H1K2   A0A182WG88   Q7PWJ1   A0A182RM00   A0A1S4GZP9   A0A182LMQ0   A0A182JAV5   A0A1W4XW64   A0A182QLE2   A0A182NUS4   A0A084W1U3   A0A1Q3FR41   A0A1Q3FQW8   A0A1B0CSL7   A0A336M353   B0WCJ8   A0A0M4E3B9   A0A0M4E327   A0A182XNU3   A0A182I7E6   A0A182SBW7   A0A182K8T6   A0A182PU68  

PDB

3B43     E-value=1.74668e-18,     Score=230

KEGG

101736663    no KO assigned | (RefSeq) protein turtle

GO

GO:0016021   GO:0007158   GO:0008366   GO:0098632   GO:0045467   GO:0005887   GO:0042065   GO:0007156   GO:0030424   GO:0005886   GO:0007411   GO:0070593   GO:0005515   GO:0004672   GO:0006468   GO:0005975   GO:0030170   GO:0015914   GO:0016020   GO:0003707   GO:0051537  

Subcellular location

Cell membrane  
Cell projection  
Axon  

SignalP

Position:   1 - 25,         Likelihood:  0.980751

 

 

Length:

664

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

24.43606

Exp number, first 60 AAs:

1.88746

Total prob of N-in:

0.10052

outside

1  -  634

TMhelix

635  -  657

inside

658  -  664

 

 

Pi

5.531683

Theta

4.23453

Tajima's D

0.156096

CLR

0.250801

CSRT

0.443777811109445

Interpretation

Uncertain