Gene

KWMTBOMO07557

Pre Gene Modal

BGIBMGA005849

Annotation

sid-1-related_gene3_precursor_[Bombyx_mori]

Location

Bomo_Chr12(+):17427577-17429407      View in EpiBrowser

Full name

SID1 transmembrane family member 1      

Location in the cell

PlasmaMembrane   Reliability : 4.657

CDS

ATGTTGTCCCGCGACCGCCTGCCATGTGTGTGTGTGTGCGCAGAGAAGTCGAGCCTGGCGGTGGCGGCGCGGGGCCTGCGGGCGCGGCCGCTGTACACGCCGCGGCTGGTCATGCTGCTCATCGCCAACGCCGCCAACTGGGGCTTCGCCATCTACGGGCTCCTGACCCATGCGGGGGACATAGCGACCCACCTGCTGAACGTGCTACTGTGCAACACGCTGCTGTACATCGTGTTCTACGTGCTGATGAAGCTGCTGCACGGGGAGCGCATCCGCTGGTACTCCTGGTGCTTCTTGGCCGCGGCGGCCGCCTGCTGGGTGCCAGCTCTCTACTTTTTTACTTCCGGCAGCACGGACTGGTCGGCGACGCCGGCGCGGTCCCGGCACCGCAACCACGAGTGCCGCGTGCTGCAGTTCTACGACTCGCACGACCTGTGGCACATGCTGTCGGCCGCCGCGCTCTACTTCACCTTCAACGTCATGCTCACCTGGGACGACGGACTCTCCGCCGTCAAACGGACAGAGATTGCCGTCTTTTGA

Protein

MLSRDRLPCVCVCAEKSSLAVAARGLRARPLYTPRLVMLLIANAANWGFAIYGLLTHAGDIATHLLNVLLCNTLLYIVFYVLMKLLHGERIRWYSWCFLAAAAACWVPALYFFTSGSTDWSATPARSRHRNHECRVLQFYDSHDLWHMLSAAALYFTFNVMLTWDDGLSAVKRTEIAVF

Description

In vitro binds long double-stranded RNA (dsRNA) (500 and 700 base pairs), but not dsRNA shorter than 300 bp. Not involved in RNA autophagy, a process in which RNA is directly imported into lysosomes in an ATP-dependent manner, and degraded.

Similarity

Belongs to the SID1 family.

Keywords

Alternative splicing   Complete proteome   Glycoprotein   Membrane   Polymorphism   Reference proteome   RNA-binding   Signal   Transmembrane   Transmembrane helix  

Feature

chain  SID1 transmembrane family member 1
splice variant  In isoform 2.
sequence variant  In dbSNP:rs9879313.

Uniprot

A9CQL1   S5RRN7   H9J8K7   A0A2W1BSL8   A0A385JPJ4   A0A2A4K1B3   + More
A0A0L7LM60   V9VMZ4   A0A212F6B3   A0A1E1W8F2   A0A194PVA2   A0A0N0PCB9   A0A2A4J7H1   A0A2A4IUB4   A0A2H1VGM1   V9VLL3   A0A1Y1KT41   A0A1Y1KTV8   B9W070   A0A1W4WGG4   A0A3S2M533   V4BXN2   D2A688   A7YFW2   A0A0N9JWV7   A9CQL3   A0A226ET70   A0A0N1I3U4   A0A059VQN8   A0A2J7RDI9   A0A194PSM1   A0A0S7K5X0   A0A067R6J9   A0A3Q2D4B8   A0A2J7RDJ2   A0A2J7RDJ6   A0A2J7RDK3   A0A3Q1JIW3   A0A3Q1JIT7   A0A3R7M6P4   A0A3B3ZUK6   A0A3Q1JPZ3   A0A1B6FZQ0   A0A2R2MI98   A0A2R2MIQ4   A0A3S2MCC8   A0A2G9QHI9   A0A3Q1JD10   A0A2R2MIB4   A0A1A8GFS2   A0A1A7YPN4   N6TBL6   U4U416   V9VIE0   K1RMY0   A0A2C9JQS9   A0A2C9JQS7   E2AJI6   A0A1D2M1A9   A0A059TD68   A0A154PER2   K7J510   A0A232EXE9   L5L359   A0A3M6TLD3   K9LY69   A0A3S2L0S6   A0A2B4SZM3   A0A2Y9QZ70   A0A0L8FH08   A0A2K6K5J0   A0A0L8FGV0   A0A2K6R5N7   A0A1S3W347   A0A2K6K5E3   A0A2K6R5P7   A0A2K5JXG8   A0A2K5JXG1   A0A1S2ZAG7   A0A2K5F514   A0A2K5MUU9   A7RYF1   A0A2K5MUX7   A0A2K5F536   F7FZS1   X2J861   A0A2J8W2K9   Q9NXL6-2   A0A2K5YEK1   A0A2K5MUV4   A0A2J8W2K3   Q9NXL6   A0A2K5YEK5   A0A2K5QBJ1   M3W303   A0A2I2V064   B4E0H9   A0A2K5QBI9   A0A337SST3   K9J2X7  

Pubmed

18201385    19121390    28756777    26227816    22118469    26354079    + More
28004739    19593438    23254933    18362917    19820115    24845553    25463417    23537049    22992520    15562597    20798317    27289101    24391810    20075255    28648823    23258410    30382153    25362486    17615350    18464734    24528536    14702039    16641997    15489334    17975172   

EMBL

AB327184    BAF95806.1    KC292008    AGS18762.1    BABH01038626    KZ149931    + More
PZC77331.1    MG696730    AXZ00255.1    NWSH01000292    PCG77684.1    JTDY01000598    KOB76515.1    KF717090    AHC98015.1    AGBW02010072    OWR49249.1    GDQN01007801    JAT83253.1    KQ459592    KPI96918.1    KQ460642    KPJ13349.1    NWSH01002727    PCG67618.1    NWSH01007994    PCG62730.1    ODYU01002469    SOQ40003.1    KF717088    AHC98013.1    GEZM01078209    GEZM01078208    JAV62855.1    GEZM01078212    GEZM01078211    JAV62846.1    FJ619650    ACM47363.1    RSAL01000031    RVE51591.1    KB201890    ESO93839.1    KQ971346    EFA05674.2    EF688529    ABU63674.1    KR153285    ALG36907.1    AB327185    BAF95807.1    LNIX01000002    OXA60011.1    KQ458887    KPJ04577.1    KF561252    AHZ97882.1    NEVH01005288    PNF38903.1    KQ459593    KPI96307.1    GBYX01220090    GBYX01220088    GBYX01220086    GBYX01220080    GBYX01220079    GBYX01220078    JAO72599.1    KK852663    KDR19041.1    PNF38907.1    PNF38902.1    PNF38905.1    QCYY01001891    ROT74464.1    GECZ01014119    JAS55650.1    CM012449    RVE64360.1    KV986914    PIO14975.1    HAEC01002538    SBQ70615.1    HADX01010375    SBP32607.1    APGK01036719    APGK01036720    APGK01036721    KB740941    ENN77664.1    KB632001    ERL87797.1    KF717089    AHC98014.1    JH817099    EKC42950.1    GL440027    EFN66381.1    LJIJ01007384    ODM86750.1    KF192314    AHY18684.1    KQ434889    KZC10355.1    NNAY01001757    OXU23015.1    KB030337    ELK18174.1    RCHS01003423    RMX42091.1    JN676095    AFQ00936.1    RSAL01000287    RVE42946.1    LSMT01000007    PFX34022.1    KQ432038    KOF62934.1    KOF62933.1    DS469553    EDO43450.1    KJ135007    AHN55087.1    NDHI03003402    PNJ64015.1    AK000181    AC055740    AC112128    BC117222    PNJ64014.1    AANG04001815    AK303385    BAG64441.1    GABZ01004366    JAA49159.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000007151    UP000053268    UP000053240    + More
UP000192223    UP000283053    UP000030746    UP000007266    UP000198287    UP000235965    UP000027135    UP000265020    UP000265040    UP000283509    UP000261520    UP000085678    UP000019118    UP000030742    UP000005408    UP000076420    UP000000311    UP000094527    UP000076502    UP000002358    UP000215335    UP000010552    UP000275408    UP000225706    UP000248480    UP000053454    UP000233180    UP000233200    UP000079721    UP000233080    UP000233020    UP000233060    UP000001593    UP000002279    UP000005640    UP000233140    UP000233040    UP000011712   

PRIDE

A9CQL1    H9J8K7    A9CQL3    Q9NXL6   

Pfam

PF13965   SID-1_RNA_chan        + More
PF00400   WD40

Interpro

IPR025958   SID1_TM_fam        + More
IPR020472   G-protein_beta_WD-40_rep       
IPR036322   WD40_repeat_dom_sf       
IPR019775   WD40_repeat_CS       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR001680   WD40_repeat       
IPR017986   WD40_repeat_dom       

SUPFAM

SSF50978   SSF50978       

Gene 3D

2.130.10.10    

ProteinModelPortal

A9CQL1   S5RRN7   H9J8K7   A0A2W1BSL8   A0A385JPJ4   A0A2A4K1B3   + More
A0A0L7LM60   V9VMZ4   A0A212F6B3   A0A1E1W8F2   A0A194PVA2   A0A0N0PCB9   A0A2A4J7H1   A0A2A4IUB4   A0A2H1VGM1   V9VLL3   A0A1Y1KT41   A0A1Y1KTV8   B9W070   A0A1W4WGG4   A0A3S2M533   V4BXN2   D2A688   A7YFW2   A0A0N9JWV7   A9CQL3   A0A226ET70   A0A0N1I3U4   A0A059VQN8   A0A2J7RDI9   A0A194PSM1   A0A0S7K5X0   A0A067R6J9   A0A3Q2D4B8   A0A2J7RDJ2   A0A2J7RDJ6   A0A2J7RDK3   A0A3Q1JIW3   A0A3Q1JIT7   A0A3R7M6P4   A0A3B3ZUK6   A0A3Q1JPZ3   A0A1B6FZQ0   A0A2R2MI98   A0A2R2MIQ4   A0A3S2MCC8   A0A2G9QHI9   A0A3Q1JD10   A0A2R2MIB4   A0A1A8GFS2   A0A1A7YPN4   N6TBL6   U4U416   V9VIE0   K1RMY0   A0A2C9JQS9   A0A2C9JQS7   E2AJI6   A0A1D2M1A9   A0A059TD68   A0A154PER2   K7J510   A0A232EXE9   L5L359   A0A3M6TLD3   K9LY69   A0A3S2L0S6   A0A2B4SZM3   A0A2Y9QZ70   A0A0L8FH08   A0A2K6K5J0   A0A0L8FGV0   A0A2K6R5N7   A0A1S3W347   A0A2K6K5E3   A0A2K6R5P7   A0A2K5JXG8   A0A2K5JXG1   A0A1S2ZAG7   A0A2K5F514   A0A2K5MUU9   A7RYF1   A0A2K5MUX7   A0A2K5F536   F7FZS1   X2J861   A0A2J8W2K9   Q9NXL6-2   A0A2K5YEK1   A0A2K5MUV4   A0A2J8W2K3   Q9NXL6   A0A2K5YEK5   A0A2K5QBJ1   M3W303   A0A2I2V064   B4E0H9   A0A2K5QBI9   A0A337SST3   K9J2X7  

KEGG

100134919    no KO assigned | (RefSeq) Sir-3; sid-1-related gene3

GO

GO:0033227   GO:0051033   GO:0016021   GO:0005764   GO:0005886   GO:0003725   GO:0050658   GO:0009058   GO:0030170   GO:0015914   GO:0016020   GO:0003707   GO:0051537  

PANTHER

PTHR12185  

Subcellular location

Membrane  

Length:

179

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

83.51569

Exp number, first 60 AAs:

21.45365

Total prob of N-in:

0.99492

POSSIBLE N-term signal

sequence

inside

1  -  36

TMhelix

37  -  59

outside

60  -  63

TMhelix

64  -  86

inside

87  -  92

TMhelix

93  -  115

outside

116  -  144

TMhelix

145  -  164

inside

165  -  179

 

 

Pi

0.696075

Theta

4.171305

Tajima's D

-2.207315

CLR

212.063544

CSRT

0.00389980500974951

Interpretation

Possibly Positive selection