Gene

KWMTBOMO07555  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005845

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_serine_palmitoyltransferase_2_[Bombyx_mori]

Location

Bomo_Chr12(+):17389097-17399330      View in EpiBrowser

Location in the cell

Mitochondrial   Reliability : 1.457 PlasmaMembrane   Reliability : 1.056

CDS

ATGAAGTCCACGCAGTCTAATGGATCAACGCCGAAGATGACACAAGTGGAGGGAGGCGGCCTGCCAAAGATAGACTGGTCCAAGTACGACACGTTCCCGGGCTCGTTCGAGAAGTGTTCCCTACTGACCGCCGTCCTCACGCACGTTGGACTTTACGTTCTCATGTTCCTGGGCTTCGTCAACCAGCTCATATTCAAGCCTAAGGCCGCCACCGAGAAGAACAGAGAGGGGTACGCTCCGCTGTACGATCCGTTCGAGCAGTTCTTCTCTCGGTACGTGTACCGGCGCGTGCGGCACTGCTTCAACCGACCGATATGCTCGGCGCCTGGAGCCGAAGTCGTCCTCAAGGAGTGGGAAAGCACCGATCACAATTGGACTTTCAAGTTCACGGGCGTGGAGCGGCGCTGCGTCAACCTGGGCTCGTACAACTACCTGGGGTTCGCGGGCGGGGAGGGCGCGGAGGGGGGCTGCGCGCGCGCCGTGGCCGACGCCGTGCGCCGCTACGGCATGGCGCAGGGCTCCTCGCGCGCCGAGCTCGGCACCACGCCGCTGCACCTCGAACTGGAACGGGCCGTGGCTGACTTCTTGGGGGTCGAGGACGCCATCGTGTTCGGAATGGGGTTCGCCACCAACACGCTGAGCATACCGGGGCTGATCGGGCCGGGCACGCTGGTGCTGAGCGACGAGAACAACCACGCGTCGCTCATCCTGGGCCTGCGCCTGTCCCGCGCCACCGTGCGCGTGTTCCGACACAACGACGTGCGCCACGCCGAGGAGCTGGCCCGCGCCGCGCTGGCCGAGCGCCGCTGGGCCAACGTGCTGCTGGTGGTGGAGGGCGTTTACAGCATGGAGGGCTCTGTGGCGGCACTGGAGGGCCTGGTGGCGTTGAAGCAGGCGCTGGGGCTGCACCTGTACGTGGACGAGGCGCACTCCGTGGGCGCTCTGGGGTCCACGGGCCGCGGCGCGCTGCAGCGGTGCCGCGTGCTCGCCGCGCACGTCGACGTGCTCATGGGCACCTTCACAAAGAGCTTCGGCGCGGCCGGGGGGTACATCGCAGGCCCGCGGCGGCTGGTGCAGTGGCTGCGCGCGCACGGGCACGCGCACGGCTACGCGCACAGCATGTCGTGCGGCGTGGCGGCGCAGGTGCTGGCGGCCGTGCGCGCGCTGGACGCGGCGCCGGGCCGGGCGCGGGTGCGGGCGCTGGCGCAGAACACGGCCTACTTCCGCCGCAGGCTGCGCGAGCTGGGCGTGGTGACGTTCGGGCACGACGACTCGCCGGTGGTGCCCATGCTGGTGTACACGTTCAGCAAGATGGCGGCCACGGTGGAGCGCCTCACGCGCGCCGGCGTCGCCACCGTCGGCGTCGGCTTCCCCGCCACGCCGCTCAACATGGCGCGCATACGTTTCTGCCTGTCGGCGTCCCACACCCGGGAGCAGCTGGACCGGTGCCTGCTGGCCGTGGAGCAGGTGGCGGACGAGCTGGGCCTGCGCTACTCGCGCCGCCGCCCCCTCGCGGAGCCCCGACCCTCGTAA

Protein

MKSTQSNGSTPKMTQVEGGGLPKIDWSKYDTFPGSFEKCSLLTAVLTHVGLYVLMFLGFVNQLIFKPKAATEKNREGYAPLYDPFEQFFSRYVYRRVRHCFNRPICSAPGAEVVLKEWESTDHNWTFKFTGVERRCVNLGSYNYLGFAGGEGAEGGCARAVADAVRRYGMAQGSSRAELGTTPLHLELERAVADFLGVEDAIVFGMGFATNTLSIPGLIGPGTLVLSDENNHASLILGLRLSRATVRVFRHNDVRHAEELARAALAERRWANVLLVVEGVYSMEGSVAALEGLVALKQALGLHLYVDEAHSVGALGSTGRGALQRCRVLAAHVDVLMGTFTKSFGAAGGYIAGPRRLVQWLRAHGHAHGYAHSMSCGVAAQVLAAVRALDAAPGRARVRALAQNTAYFRRRLRELGVVTFGHDDSPVVPMLVYTFSKMAATVERLTRAGVATVGVGFPATPLNMARIRFCLSASHTREQLDRCLLAVEQVADELGLRYSRRRPLAEPRPS

Cofactor

pyridoxal 5'-phosphate

Similarity

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

Uniprot

A0A2A4K1P8   A0A2W1BZS8   A0A212F698   A0A158NY18   A0A195B8H6   A0A151IP31   + More
A0A026VZ82   A0A0M9AA63   A0A182RBK6   A0A182Q3Y9   A0A182WT69   A0A182K1L1   A0A182V261   A0A151XBX8   A0A182W9P1   Q7Q3L8   A0A182HV64   A0A182L221   B0WCF6   A0A182YGT1   A0A1Q3F4Y2   A0A0A1WS35   A0A182MMX8   A0A1Q3F4Y8   A0A1Q3F4V7   Q17NH0   A0A034VLY0   A0A2M4ABT3   A0A195ED96   A0A0K8TSM6   E0VJB0   A0A1I8P7C6   A0A0C9RPX1   U5ETZ0   A0A087ZUZ3   A0A2A3E7E8   A0A1I8P7D0   A0A1I8P7H7   A0A0L7QRX2   A0A3L8D794   T1PIW1   A0A195FVQ6   A0A1B0GFA4   A0A067QVU3   A0A1A9YHI8   A0A1B0BKV9   A0A1A9Z8S9   A0A1J1HJE5   A0A1A9UT64   A0A1C9HJI7   B4MZ05   A0A3B0JNA3   A0A1W4VXB6   A0A1B0CZA0   A0A182F4K2   A0A1A9WUG2   B4NYA7   B4KLH6   B4HXQ8   B4LV60   A0A0R3P097   A0A0K8VNZ7   A0A2M4CZ25   B4Q6F5   B3N1C4   A0A0A9YLX6   B3N5Z3   Q9U912   Q9V3F2   D2A127   T1GSU6   Q29KV1   A0A0L0BRZ4   A0A139WJA7   B4GSS3   A0A1B6MR50   B4JQU7   E2BWP3   A0A1W4X4X2   A0A0V0G875   A0A1B6ERD8   A0A069DV97   A0A023F3S2   A0A1B6D108   A0A336KAB7   W5JH40   K7IQJ6   A0A2J7QIG8   A0A1L8DIN3   A0A224XHP9   A0A2R7W4H8   A0A0P4VWX8   A0A1Y1L908   A0A232FF07   A0A182HDR6   V5G047   A0A154PPN6   A0A0J7LAU3   T1I3Z1  

Pubmed

28756777    22118469    21347285    24508170    12364791    14747013    + More
17210077    20966253    25244985    25830018    17510324    25348373    26369729    20566863    30249741    25315136    24845553    17994087    17550304    15632085    22936249    25401762    26823975    10490662    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18362917    19820115    26108605    20798317    26334808    25474469    20920257    23761445    20075255    27129103    28004739    28648823    26483478   

EMBL

NWSH01000292    PCG77683.1    KZ149931    PZC77333.1    AGBW02010072    OWR49248.1    + More
ADTU01002896    ADTU01002897    KQ976565    KYM80545.1    KQ976892    KYN07232.1    KK107558    EZA48985.1    KQ435701    KOX80375.1    AXCN02000864    KQ982316    KYQ57849.1    AAAB01008964    EAA12895.4    APCN01002494    DS231887    EDS43480.1    GFDL01012430    JAV22615.1    GBXI01012423    JAD01869.1    AXCM01005688    GFDL01012438    JAV22607.1    GFDL01012443    JAV22602.1    CH477199    EAT48248.1    GAKP01016157    JAC42795.1    GGFK01004747    MBW38068.1    KQ979074    KYN22792.1    GDAI01000224    JAI17379.1    DS235221    EEB13466.1    GBYB01010545    JAG80312.1    GANO01002566    JAB57305.1    KZ288345    PBC27635.1    KQ414766    KOC61385.1    QOIP01000012    RLU16159.1    KA647858    AFP62487.1    KQ981215    KYN44506.1    CCAG010012796    KK852886    KDR14360.1    JXJN01016056    CVRI01000001    CRK86590.1    KU737582    AOO86839.1    CH963913    EDW77344.1    OUUW01000006    SPP81832.1    AJVK01002205    AJVK01002206    CM000157    EDW89743.1    CH933807    EDW12857.1    CH480818    EDW51838.1    CH940649    EDW64320.1    CH379061    KRT04704.1    GDHF01027571    GDHF01011736    JAI24743.1    JAI40578.1    GGFL01006406    MBW70584.1    CM000361    CM002910    EDX05137.1    KMY90380.1    CH902652    EDV33645.2    GBHO01013054    GBRD01014680    GDHC01006864    JAG30550.1    JAG51146.1    JAQ11765.1    CH954177    EDV58031.1    AB017359    BAA83721.1    AE014134    AY095191    AAF53465.1    AAM12284.1    AHN54471.1    KQ971338    EFA02596.1    CAQQ02393656    CAQQ02393657    EAL33073.1    JRES01001454    KNC22812.1    KYB28108.1    CH479189    EDW25432.1    GEBQ01001591    JAT38386.1    CH916372    EDV99277.1    GL451165    EFN79898.1    GECL01001910    JAP04214.1    GECZ01029277    JAS40492.1    GBGD01001054    JAC87835.1    GBBI01002652    JAC16060.1    GEDC01018023    JAS19275.1    UFQS01000215    UFQT01000215    SSX01441.1    SSX21821.1    ADMH02001514    ETN62230.1    NEVH01013595    PNF28381.1    GFDF01007793    JAV06291.1    GFTR01007098    JAW09328.1    KK854321    PTY14633.1    GDKW01002502    JAI54093.1    GEZM01063137    JAV69281.1    NNAY01000360    OXU28897.1    JXUM01034762    JXUM01034763    KQ561035    KXJ79952.1    GALX01005136    JAB63330.1    KQ435007    KZC13707.1    LBMM01000102    KMR04938.1    ACPB03003297   

Proteomes

UP000218220    UP000007151    UP000005205    UP000078540    UP000078542    UP000053097    + More
UP000053105    UP000075900    UP000075886    UP000076407    UP000075881    UP000075903    UP000075809    UP000075920    UP000007062    UP000075840    UP000075882    UP000002320    UP000076408    UP000075883    UP000008820    UP000078492    UP000009046    UP000095300    UP000005203    UP000242457    UP000053825    UP000279307    UP000095301    UP000078541    UP000092444    UP000027135    UP000092443    UP000092460    UP000092445    UP000183832    UP000078200    UP000007798    UP000268350    UP000192221    UP000092462    UP000069272    UP000091820    UP000002282    UP000009192    UP000001292    UP000008792    UP000001819    UP000000304    UP000007801    UP000008711    UP000000803    UP000007266    UP000015102    UP000037069    UP000008744    UP000001070    UP000008237    UP000192223    UP000000673    UP000002358    UP000235965    UP000215335    UP000069940    UP000249989    UP000076502    UP000036403    UP000015103   

PRIDE

Q9U912    Q9V3F2   

Pfam

PF00155   Aminotran_1_2        + More
PF00168   C2

Interpro

IPR015421   PyrdxlP-dep_Trfase_major        + More
IPR015424   PyrdxlP-dep_Trfase       
IPR004839   Aminotransferase_I/II       
IPR001917   Aminotrans_II_pyridoxalP_BS       
IPR015422   PyrdxlP-dep_Trfase_dom1       
IPR035892   C2_domain_sf       
IPR001565   Synaptotagmin       
IPR000008   C2_dom       

SUPFAM

SSF53383   SSF53383       

Gene 3D

3.40.640.10     3.90.1150.10     2.60.40.150    

ProteinModelPortal

A0A2A4K1P8   A0A2W1BZS8   A0A212F698   A0A158NY18   A0A195B8H6   A0A151IP31   + More
A0A026VZ82   A0A0M9AA63   A0A182RBK6   A0A182Q3Y9   A0A182WT69   A0A182K1L1   A0A182V261   A0A151XBX8   A0A182W9P1   Q7Q3L8   A0A182HV64   A0A182L221   B0WCF6   A0A182YGT1   A0A1Q3F4Y2   A0A0A1WS35   A0A182MMX8   A0A1Q3F4Y8   A0A1Q3F4V7   Q17NH0   A0A034VLY0   A0A2M4ABT3   A0A195ED96   A0A0K8TSM6   E0VJB0   A0A1I8P7C6   A0A0C9RPX1   U5ETZ0   A0A087ZUZ3   A0A2A3E7E8   A0A1I8P7D0   A0A1I8P7H7   A0A0L7QRX2   A0A3L8D794   T1PIW1   A0A195FVQ6   A0A1B0GFA4   A0A067QVU3   A0A1A9YHI8   A0A1B0BKV9   A0A1A9Z8S9   A0A1J1HJE5   A0A1A9UT64   A0A1C9HJI7   B4MZ05   A0A3B0JNA3   A0A1W4VXB6   A0A1B0CZA0   A0A182F4K2   A0A1A9WUG2   B4NYA7   B4KLH6   B4HXQ8   B4LV60   A0A0R3P097   A0A0K8VNZ7   A0A2M4CZ25   B4Q6F5   B3N1C4   A0A0A9YLX6   B3N5Z3   Q9U912   Q9V3F2   D2A127   T1GSU6   Q29KV1   A0A0L0BRZ4   A0A139WJA7   B4GSS3   A0A1B6MR50   B4JQU7   E2BWP3   A0A1W4X4X2   A0A0V0G875   A0A1B6ERD8   A0A069DV97   A0A023F3S2   A0A1B6D108   A0A336KAB7   W5JH40   K7IQJ6   A0A2J7QIG8   A0A1L8DIN3   A0A224XHP9   A0A2R7W4H8   A0A0P4VWX8   A0A1Y1L908   A0A232FF07   A0A182HDR6   V5G047   A0A154PPN6   A0A0J7LAU3   T1I3Z1  

PDB

3TQX     E-value=1.05899e-43,     Score=446

KEGG

101739306    K00654 serine palmitoyltransferase [EC:2.3.1.50] | (RefSeq) serine palmitoyltransferase 2

PATHWAY

00600    Sphingolipid metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0030170   GO:0016021   GO:0016740   GO:0009058   GO:0004758   GO:0008483   GO:0005886   GO:0030148   GO:0007444   GO:0016874   GO:0012505   GO:0008152   GO:0003824   GO:0015914   GO:0016020   GO:0003707   GO:0051537  

Length:

510

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

27.10976

Exp number, first 60 AAs:

19.04659

Total prob of N-in:

0.66206

POSSIBLE N-term signal

sequence

inside

1  -  38

TMhelix

39  -  61

outside

62  -  510

 

 

Pi

1.293205

Theta

7.147803

Tajima's D

-2.403671

CLR

184.495986

CSRT

0.00109994500274986

Interpretation

Possibly Positive selection