Gene

KWMTBOMO07551

Annotation

PREDICTED:_DNA-binding_protein_D-ETS-6-like_[Bombyx_mori]

Location

Bomo_Chr12(+):17305987-17309039      View in EpiBrowser

Full name

Protein FEV      

Alternative Name

PC12 ETS domain-containing transcription factor 1
Fifth Ewing variant protein

Transcription factor

ETS

Location in the cell

Nuclear   Reliability : 2.22

CDS

ATGGCATCACGCTATGGGTATGCGGCTCTGAGTGCACGCGCTGGAGGAGGACAGGTGCAGCTCTGGCAGTTCCTGCTGGAGGAGCTGGCTGCAGGAGCTCCTGGAATCTGTTGGGAGGGTCCCCCTGGTGATGGAGAGTTCCGCCTGTCGGATCCGGATGAGGTGGCCCGGCGCTGGGGCCGGCGCAAACAGAAACCCAACATGAACTACGACAAACTATCGCGAGCGCTGCGGTACTATTATGATAAGAACATCATGAGCAAGGTACACGGGAAGCGCTACGCGTACAGGTTCAGTTGGGCGGGTCTGACCGCGGCGTGCCAGGCGCAGGCTCCGGACGCGCCCCCCTACTGGCACTACCTCCCGCCCCCCGGACACCCCCCGCAACATGTCCACGGGAACATCCACAGCTCGCAGCAGACCTAG

Protein

MASRYGYAALSARAGGGQVQLWQFLLEELAAGAPGICWEGPPGDGEFRLSDPDEVARRWGRRKQKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFSWAGLTAACQAQAPDAPPYWHYLPPPGHPPQHVHGNIHSSQQT

Description

Functions as a transcriptional regulator. May function as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.
Functions as a transcriptional regulator. According to PubMed:12761502, it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.

Similarity

Belongs to the ETS family.

Keywords

Complete proteome   Developmental protein   Differentiation   DNA-binding   Neurogenesis   Nucleus   Reference proteome   Transcription   Transcription regulation   3D-structure   Chromosomal rearrangement  

Feature

chain  Protein FEV

Uniprot

A0A2R8ZHN2   A0A341CW01   G3UMM1   A0A2K5Z6W4   A0A2K5HJU7   I3MXW7   + More
A0A2U3YH87   F6WXL8   A0A0H2UHP3   G3WPL0   H0WCZ3   A0A384AL72   A0A0D9R8A4   A0A096N222   A0A2K5NMZ5   A0A2K6E7N4   A0A2K5X8V4   A0A2K6NPL9   O70132   Q8QZW2   A0A2Y9FUM8   A0A2K6N6R6   A0A2J8TUA6   A0A340WFE6   G3R5E2   A0A2I3RTZ5   Q99581   A0A2U4BMK6   A0A2R8MR30   W5QET0   A0A2K5RYE6   M3YYN9   A0A1U7QPQ1   A0A2K6GMR6  

Pubmed

22722832    17495919    15057822    21709235    21993624    25362486    + More
9468386    10575032    11875656    15489334    14602809    12546819    17656160    22398555    16136131    9121764    15815621    12761502    15003288    15986391    17172842    17597646    20809919   

EMBL

AJFE02063764    AJFE02063765    AGTP01062686    AGTP01062687    AC132020    AEFK01132713    + More
AEFK01132714    AAKN02049531    AQIB01003880    AHZZ02004557    AQIA01015930    U91679    AY049085    AY049086    CH466548    BC138435    BC138436    NDHI03003483    PNJ36586.1    CABD030018694    AACZ04056567    NBAG03000230    PNI70823.1    Y08976    AC097468    CH471063    BC023511    AMGL01056043    AEYP01056834   

Proteomes

UP000240080    UP000252040    UP000007646    UP000233140    UP000233080    UP000005215    + More
UP000245341    UP000002280    UP000002494    UP000007648    UP000005447    UP000261681    UP000029965    UP000028761    UP000233060    UP000233120    UP000233100    UP000233200    UP000000589    UP000248484    UP000233180    UP000265300    UP000001519    UP000002277    UP000005640    UP000245320    UP000008225    UP000002356    UP000233040    UP000000715    UP000189706    UP000233160   

PRIDE

O70132    Q8QZW2    Q99581   

Pfam

PF00178   Ets

Interpro

IPR000418   Ets_dom        + More
IPR036388   WH-like_DNA-bd_sf       
IPR036390   WH_DNA-bd_sf       

SUPFAM

SSF46785   SSF46785       

Gene 3D

1.10.10.10    

ProteinModelPortal

A0A2R8ZHN2   A0A341CW01   G3UMM1   A0A2K5Z6W4   A0A2K5HJU7   I3MXW7   + More
A0A2U3YH87   F6WXL8   A0A0H2UHP3   G3WPL0   H0WCZ3   A0A384AL72   A0A0D9R8A4   A0A096N222   A0A2K5NMZ5   A0A2K6E7N4   A0A2K5X8V4   A0A2K6NPL9   O70132   Q8QZW2   A0A2Y9FUM8   A0A2K6N6R6   A0A2J8TUA6   A0A340WFE6   G3R5E2   A0A2I3RTZ5   Q99581   A0A2U4BMK6   A0A2R8MR30   W5QET0   A0A2K5RYE6   M3YYN9   A0A1U7QPQ1   A0A2K6GMR6  

PDB

3ZP5     E-value=7.42028e-32,     Score=336

KEGG

101737489    K09443 ETS-type family, other | (RefSeq) DNA-binding protein D-ETS-6-like

GO

GO:0005634   GO:0010628   GO:0043565   GO:0048665   GO:0042551   GO:0003700   GO:0016607   GO:0030154   GO:0000981   GO:0006357   GO:0007399   GO:0045944   GO:0003690   GO:0001228   GO:0000978   GO:0045893   GO:0051611   GO:0043025   GO:1905627   GO:0006366   GO:0003714   GO:0006355   GO:0004190   GO:0006508   GO:0015914   GO:0016021   GO:0016020   GO:0003707   GO:0051537  

Subcellular location

Nucleus  

Length:

141

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.17639

Exp number, first 60 AAs:

0.01726

Total prob of N-in:

0.20835

outside

1  -  141

 

 

Pi

20.68444

Theta

25.748273

Tajima's D

-0.602555

CLR

0.534124

CSRT

0.217089145542723

Interpretation

Uncertain