Gene

KWMTBOMO07537

Pre Gene Modal

BGIBMGA005869

Annotation

PREDICTED:_DNA_replication_complex_GINS_protein_PSF1-like_[Plutella_xylostella]

Location

Bomo_Chr12(-):17113224-17115176      View in EpiBrowser

Full name

DNA replication complex GINS protein PSF1      

Alternative Name

GINS complex subunit 1

Location in the cell

Nuclear   Reliability : 3.433

CDS

ATGTTCGCAGAAAAAGTTATAGAACTAATTAAAGAAGTAGATAGAAATCCTGACACAATAGATCAATATAATGATGAAAAAATACGCCAAATAATAGAAGAAATGCATTTATTATTTAAATTGAACATGAATGATGCTAATGCTACAACAGAAAACAGATCATTGTGGACCACAGTTCAAGTAAGACATTCTGCCCTTGAACGCAATAAAAGGTGTATATTAGCCTATCTCTACAACAGAATGAAAAAAATTAAGACATTACGTTGGGAATTTGGTGCAGTACTACCTCCAGATATCAGAGAATTGCTTTCTGATGATGAATATCAATGGTTTTCAAAATACTCTGGAAATCTTGCTTTGTATATGAGATCTTTAGGCCAAGATATAGGATACAGTGGCATAGACTTGACTGAAAATTTAAAGCCCCCTAAATCATTGTTCATCGAAGTGCTTTGTGTTGTGGATTATGGTAAATTAGAACTTGAAGATGGTGATGTGGTTATGCTTAAGAAGAATAGCAGACATTATCTTCCTACTTCGGAATGTCAGACTTTAATACGACAGGGTATTCTGAAACAAATAATGTGA

Protein

MFAEKVIELIKEVDRNPDTIDQYNDEKIRQIIEEMHLLFKLNMNDANATTENRSLWTTVQVRHSALERNKRCILAYLYNRMKKIKTLRWEFGAVLPPDIRELLSDDEYQWFSKYSGNLALYMRSLGQDIGYSGIDLTENLKPPKSLFIEVLCVVDYGKLELEDGDVVMLKKNSRHYLPTSECQTLIRQGILKQIM

Description

Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

Subunit

Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro.

Similarity

Belongs to the GINS1/PSF1 family.

Keywords

Complete proteome   DNA replication   Nucleus   Reference proteome  

Feature

chain  DNA replication complex GINS protein PSF1

Uniprot

A0A1E1VYQ2   S4PFR2   A0A194PU91   A0A2W1BQR7   A0A0N1I944   A0A2A4JCZ6   + More
A0A2H1VK42   A0A3S2NH85   A0A212F680   A0A0L7KXK1   C3XR78   A0A1S3IV78   A7SVK7   K1R2F6   A0A1I8PL06   W8C2C7   A0A067R829   A0A1I8NFK5   B3M8X8   H2ZEV3   A0A0L0BRK7   A0A0M4EY07   B4MGQ9   A0A3R7PNL8   A0A034WQ23   A0A0K8TW82   A0A3B0JXX8   A0A2B4SGN1   B3NB77   B4HVQ2   B4PD56   B4MN91   B4QLY5   A0A0J9RLF3   Q9W0I7   H2XZ76   B5DQY2   B4H5E4   A0A3M6TUG0   B4KXY1   A0A2P2I8F2   A0A369SLU1   B4IYK4   T2MD54   A0A0P6JH59   E9GIC5   A0A1W4VVE4   A0A0L8GFI9   D7EIS4   F7EGJ1   A0A3S0ZL89   R7VH77   A0A154PBC0   E0VNU1   Q7ZT47   G3WYP1   G1KPP9   A0A3B1J2V7   A0A2I4CGG4   A0A2A3EDQ7   A0A087ZYR6   A0A2T7NXD7   A0A1B0A065   M3XLH2   A0A0C9RDB2   A0A1A9VRC7   A0A1B0FAE8   A0A3Q0EF59   A0A151M1H2   A0A3Q2ZIN7   A0A3P9A9S4   W5NJA9   A0A3Q3DZB2   A0A1A9XDT7   A0A1B0B8G5   G3PER8   A0A060W7E6   B9ENG0   B5DES7   S4RZP9   A0A3N0XWV6   A0A3B3ZYG5   V9L7Z5   C1BJP7   A0A2U9CDS9   Q5XJQ9   A0A3B4EPW3   A0A1A9WCI0   A0A3B4WJ87   A0A3B4TF60   A0A3P8NKH4   A0A3P9B601   A0A0P6JEF3   A0A3B4GRK1   A0A3Q2VHN7   Q9CZ15   A0A0L7RDJ7   I3JJ64   A0A2Y9DKX3  

Pubmed

23622113    26354079    28756777    22118469    26227816    18563158    + More
17615350    22992520    24495485    24845553    25315136    17994087    26108605    25348373    17550304    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    12481130    15114417    15632085    30382153    30042472    24065732    21292972    18362917    19820115    17495919    23254933    20566863    12730133    27762356    21709235    25329095    9215903    22293439    25069045    24755649    20433749    20431018    25463417    24402279    25186727    16141072    21183079   

EMBL

GDQN01011240    JAT79814.1    GAIX01003912    JAA88648.1    KQ459592    KPI96887.1    + More
KZ149931    PZC77358.1    KQ460642    KPJ13324.1    NWSH01002048    PCG69310.1    ODYU01002744    SOQ40624.1    RSAL01000101    RVE47504.1    AGBW02010072    OWR49224.1    JTDY01004576    KOB67993.1    GG666456    EEN69196.1    DS469838    EDO32255.1    JH818849    EKC37719.1    GAMC01000538    JAC06018.1    KK852637    KDR19699.1    CH902618    EDV38922.1    JRES01001467    KNC22672.1    CP012525    ALC42970.1    CH940682    EDW57125.1    QCYY01002184    ROT72272.1    GAKP01002662    JAC56290.1    GDHF01033761    GDHF01019104    JAI18553.1    JAI33210.1    OUUW01000012    SPP86927.1    LSMT01000087    PFX28249.1    CH954178    EDV50130.1    CH480817    EDW50017.1    CM000159    EDW92804.2    CH963847    EDW73647.1    CM000363    EDX08771.1    CM002912    KMY96773.1    AE014296    BT025002    AAF47459.2    ABE01232.1    EAAA01002037    CH379070    EDY73969.1    CH479211    EDW32996.1    RCHS01002927    RMX44928.1    CH933809    EDW17653.1    IACF01004607    LAB70196.1    NOWV01000003    RDD47454.1    CH916366    EDV95514.1    HAAD01003817    CDG70049.1    GDIP01065810    GDIQ01007889    JAM37905.1    JAN86848.1    GL732546    EFX80795.1    KQ422015    KOF75776.1    DS497685    EFA12251.1    RQTK01000397    RUS80353.1    AMQN01003927    AMQN01026028    KB305852    KB292234    ELU00601.1    ELU17932.1    KQ434864    KZC09107.1    DS235354    EEB15047.1    BC072857    AB097168    CM004475    AAH72857.1    BAC66458.1    OCT77784.1    AEFK01029041    AEFK01029042    KZ288269    PBC29913.1    PZQS01000008    PVD25822.1    AFYH01143668    AFYH01143669    AFYH01143670    GBYB01004936    JAG74703.1    CCAG010008635    AKHW03006817    KYO18367.1    AHAT01001756    JXJN01009934    FR904369    CDQ61159.1    BT057185    ACM09057.1    AAMC01070527    BC168788    BC170763    BC170767    AAI68788.1    AAI70763.1    RJVU01057857    ROK15749.1    JW875782    AFP08299.1    BT074826    ACO09250.1    CP026257    AWP14741.1    BC083239    AAH83239.1    GEBF01004656    JAN98976.1    AK013116    KQ414613    KOC69062.1    AERX01045888   

Proteomes

UP000053268    UP000053240    UP000218220    UP000283053    UP000007151    UP000037510    + More
UP000001554    UP000085678    UP000001593    UP000005408    UP000095300    UP000027135    UP000095301    UP000007801    UP000007875    UP000037069    UP000092553    UP000008792    UP000283509    UP000268350    UP000225706    UP000008711    UP000001292    UP000002282    UP000007798    UP000000304    UP000000803    UP000008144    UP000001819    UP000008744    UP000275408    UP000009192    UP000253843    UP000001070    UP000000305    UP000192221    UP000053454    UP000007266    UP000002280    UP000271974    UP000014760    UP000076502    UP000009046    UP000186698    UP000007648    UP000001646    UP000018467    UP000192220    UP000242457    UP000005203    UP000245119    UP000092445    UP000008672    UP000078200    UP000092444    UP000189704    UP000050525    UP000264800    UP000265140    UP000018468    UP000261660    UP000092443    UP000092460    UP000007635    UP000193380    UP000087266    UP000008143    UP000245300    UP000261520    UP000246464    UP000261440    UP000091820    UP000261360    UP000261420    UP000265100    UP000265160    UP000261460    UP000264840    UP000000589    UP000053825    UP000005207    UP000248480   

PRIDE

Q9W0I7    Q9CZ15   

Pfam

PF05916   Sld5

Interpro

IPR036224   GINS_bundle-like_dom_sf        + More
IPR021151   GINS_A       
IPR005339   GINS_Psf1       

SUPFAM

SSF158573   SSF158573       

CDD

cd11710  GINS_A_psf1

ProteinModelPortal

A0A1E1VYQ2   S4PFR2   A0A194PU91   A0A2W1BQR7   A0A0N1I944   A0A2A4JCZ6   + More
A0A2H1VK42   A0A3S2NH85   A0A212F680   A0A0L7KXK1   C3XR78   A0A1S3IV78   A7SVK7   K1R2F6   A0A1I8PL06   W8C2C7   A0A067R829   A0A1I8NFK5   B3M8X8   H2ZEV3   A0A0L0BRK7   A0A0M4EY07   B4MGQ9   A0A3R7PNL8   A0A034WQ23   A0A0K8TW82   A0A3B0JXX8   A0A2B4SGN1   B3NB77   B4HVQ2   B4PD56   B4MN91   B4QLY5   A0A0J9RLF3   Q9W0I7   H2XZ76   B5DQY2   B4H5E4   A0A3M6TUG0   B4KXY1   A0A2P2I8F2   A0A369SLU1   B4IYK4   T2MD54   A0A0P6JH59   E9GIC5   A0A1W4VVE4   A0A0L8GFI9   D7EIS4   F7EGJ1   A0A3S0ZL89   R7VH77   A0A154PBC0   E0VNU1   Q7ZT47   G3WYP1   G1KPP9   A0A3B1J2V7   A0A2I4CGG4   A0A2A3EDQ7   A0A087ZYR6   A0A2T7NXD7   A0A1B0A065   M3XLH2   A0A0C9RDB2   A0A1A9VRC7   A0A1B0FAE8   A0A3Q0EF59   A0A151M1H2   A0A3Q2ZIN7   A0A3P9A9S4   W5NJA9   A0A3Q3DZB2   A0A1A9XDT7   A0A1B0B8G5   G3PER8   A0A060W7E6   B9ENG0   B5DES7   S4RZP9   A0A3N0XWV6   A0A3B3ZYG5   V9L7Z5   C1BJP7   A0A2U9CDS9   Q5XJQ9   A0A3B4EPW3   A0A1A9WCI0   A0A3B4WJ87   A0A3B4TF60   A0A3P8NKH4   A0A3P9B601   A0A0P6JEF3   A0A3B4GRK1   A0A3Q2VHN7   Q9CZ15   A0A0L7RDJ7   I3JJ64   A0A2Y9DKX3  

PDB

2Q9Q     E-value=1.15009e-50,     Score=501

KEGG

101738610    K10732 GINS complex subunit 1 | (RefSeq) DNA replication complex GINS protein PSF1-like

GO

GO:0006260   GO:0000811   GO:0005634   GO:1902983   GO:0043138   GO:1900087   GO:0032508   GO:0001833   GO:0005737   GO:0003682   GO:0015074   GO:0004190   GO:0006508   GO:0015914   GO:0016021   GO:0016020   GO:0003707   GO:0051537  

PANTHER

PTHR12914  

Subcellular location

Nucleus  

Length:

195

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04638

outside

1  -  195

 

 

Pi

12.221252

Theta

17.755131

Tajima's D

-1.127817

CLR

0

CSRT

0.112944352782361

Interpretation

Uncertain