Gene

KWMTBOMO07508

Annotation

UDP-glycosyltransferase_UGT46B1_[Helicoverpa_armigera]

Location

Bomo_Chr12(+):15252138-15257647      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

Extracellular   Reliability : 1.118

CDS

ATGAAAGCCATAATCAACGCTTTTGCTCGTTTACCACAAACAATATTTTGGAAATGGGAGGACGATATCTCAGACGCGATAAAAATACCAAAGAACGTTAAATTTGAAAAATGGTTGCCGCAATACGATTTGTTGAACCAGCAAAATTGCTTGGCATTTATCACACACGGCGGTCTACTTAGCTTGACGGAGGCAGTCGCGTCAAGCGTGCCGACTCTCATTATTCCTATACTCGGAGATCAGTTCGGGAACGCGGCCCATGCTCAGAAAGCTGGCGTCGCCGAGGTTCTAAGTCTTACGGAAATTGAAGAAGACGTGTTCTATAATAAACTCTTATCAGTTTTGTCTAAGGAGAAACGTCAGAAAGCTAAATTACTAACAAGTCTTTGGCGGGATCGTCCTCAACCGGCAATGGAAACGGCCCTATTCAACATAGAACTCGTAGCGCGACATAAAGGACTGGATATGTCGTCTGACCTATATTTCCGTAATTTATTGTTACCCACCTGTTTTGGGAATTCGTTAATAGCCATGAGCACTGCTAAGCTAATGCTCATAGCTGGAGAGCTTAAGAGGAATCAGCAAAGAGTTCCAGTACAAAACTACTACTAA

Protein

MKAIINAFARLPQTIFWKWEDDISDAIKIPKNVKFEKWLPQYDLLNQQNCLAFITHGGLLSLTEAVASSVPTLIIPILGDQFGNAAHAQKAGVAEVLSLTEIEEDVFYNKLLSVLSKEKRQKAKLLTSLWRDRPQPAMETALFNIELVARHKGLDMSSDLYFRNLLLPTCFGNSLIAMSTAKLMLIAGELKRNQQRVPVQNYY

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

A0A2H1VU07   G9LPR8   A0A2A4JI28   V5H2B2   A0A2H8TIZ0   A0A1Y1LMI4   + More
A0A1Y1LL43   A0A1Y1LIT5   A0A2H4WB74   A0A1L8D6F8   A0A1W4WYE4   A0A1W4WMF1   A0A1W4WMC9   D2A2V5   A0A286MXP5   A0A1W4WY61   A0A139WIW7   A0A212EWF8   S4PCR1   A0A191T1N3   A0A286MXP6   G9LPP9   G9LPR5   A0A2S2PC03   A0A2H8TVS6   A0A2D1GSK6   V9IL65   A0A2A4JHL4   J9KB24   A0A1W7R8H2   J9K7F3   A0A182GYX7   A0A2D1GSG4   A0A1B6KVV9   A0A2H1W091   A0A3S2PBM0   A0A2D1GSL9   A0A1B6L8F2   A0A1B6FW51   A0A194PN21   A0A1B6KXR8   A0A1B6F5J1   A0A2R4FXJ3   Q17KZ7   A0A2H1W5A1   A0A2S2P7P3   G9LPV9   A0A2S2NP66   A0A2A4K0B3   A0A1S4EZ13   G9LPV6   A0A0L7L3K3   N6UB74   A0A087ZYR9   J3JVI3   A0A191T1L9   A0A2D1GSI9   A0A0P5JI56   A0A2D1GSF6   A0A2J7R4T0   A0A2P8ZG78   A0A3S2N8S7   A0A336LTZ6   A0A2H8TXR1   A0A026WYL1   A0A3L8DPI9   A0A2S2R018   A0A2D1GSM0   A0A1D2MYE5   A0A1S3CYB2   A0A194PHJ2   X1WIH9   A0A0P5D4L6   A0A162P1L4   A0A1D2NEE8   A0A0P6E0N5   A0A0N8CHL9   A0A194PIG8   A0A2P8ZG70   E9HIB8   V5GU86   A0A0P5VPG3   A0A2J7R4W0   A0A0N8DAL2   A0A0L7RH14   A0A226DZS8   A0A023R9H7   A0A2H1VD70   A0A067RAP7   B0VZV7   A0A023R6Z5   A0A2H8TRY0   A0A2J7R4W5   A0A191T1P6   G9LPR3   N6UH99   A0A1B6E1B5   A0A1B6DPF5   A0A1B6DAQ2   A0A1B6CCZ4  

EC Number

2.4.1.17

Pubmed

22155036    28004739    29027758    18362917    19820115    19954531    + More
25299618    22118469    23622113    26483478    26354079    17510324    26227816    23537049    22516182    29403074    24508170    30249741    27289101    21292972    24727020    24845553   

EMBL

ODYU01004162    SOQ43734.1    JQ070225    AEW43141.1    NWSH01001496    PCG71080.1    + More
GALX01001513    JAB66953.1    GFXV01002302    MBW14107.1    GEZM01054554    JAV73560.1    GEZM01054556    JAV73558.1    GEZM01054555    JAV73559.1    KY202936    AUC64280.1    GEYN01000098    JAV02031.1    KQ971338    EFA02977.2    MF684363    ASX93997.1    KYB27856.1    AGBW02012000    OWR45816.1    GAIX01004036    JAA88524.1    KU680308    ANI22014.1    MF684364    ASX93998.1    JQ070206    AEW43122.1    JQ070222    AEW43138.1    GGMR01014372    MBY26991.1    GFXV01005857    MBW17662.1    MF471430    ATN96036.1    JR050268    AEY61216.1    NWSH01001552    PCG70882.1    ABLF02020518    ABLF02020523    ABLF02020526    GEHC01000199    JAV47446.1    ABLF02020524    ABLF02020525    JXUM01021599    KQ560606    KXJ81644.1    MF471406    ATN96012.1    GEBQ01024407    JAT15570.1    ODYU01005418    SOQ46242.1    RSAL01000119    RVE46733.1    MF471452    ATN96058.1    GEBQ01020086    JAT19891.1    GECZ01015337    JAS54432.1    KQ459604    KPI92520.1    GEBQ01023933    JAT16044.1    GECZ01024322    GECZ01008492    JAS45447.1    JAS61277.1    MF034860    AVT42226.1    CH477220    EAT47358.1    ODYU01006427    SOQ48259.1    GGMR01012806    MBY25425.1    JQ070266    AEW43182.1    GGMR01005927    MBY18546.1    NWSH01000322    PCG77489.1    JQ070263    AEW43179.1    JTDY01003254    KOB69869.1    APGK01030497    APGK01030498    KB740774    ENN78970.1    BT127251    AEE62213.1    KU680293    ANI21999.1    MF471426    ATN96032.1    GDIQ01202544    JAK49181.1    MF471427    ATN96033.1    NEVH01007402    PNF35837.1    PYGN01000068    PSN55501.1    RSAL01000196    RVE44553.1    UFQT01000109    SSX20153.1    GFXV01007278    MBW19083.1    KK107063    EZA61120.1    QOIP01000005    RLU22281.1    GGMS01013519    MBY82722.1    MF471451    ATN96057.1    LJIJ01000389    ODM98012.1    KPI92518.1    ABLF02037495    ABLF02037496    ABLF02037503    GDIP01162987    JAJ60415.1    LRGB01000512    KZS18442.1    LJIJ01000067    ODN03640.1    GDIQ01074138    JAN20599.1    GDIP01130895    JAL72819.1    KPI92519.1    PSN55494.1    GL732654    EFX68472.1    GALX01004658    JAB63808.1    GDIP01097242    JAM06473.1    PNF35865.1    GDIP01052551    JAM51164.1    KQ414596    KOC70104.1    LNIX01000009    OXA50201.1    KJ584814    AHX56940.1    ODYU01001909    SOQ38775.1    KK852590    KDR20745.1    DS231815    EDS35199.1    KJ584823    AHX56948.1    GFXV01004547    MBW16352.1    PNF35871.1    KU680306    ANI22012.1    JQ070220    AEW43136.1    APGK01025969    KB740608    ENN80011.1    GEDC01005597    JAS31701.1    GEDC01009759    JAS27539.1    GEDC01014521    JAS22777.1    GEDC01025996    JAS11302.1   

Proteomes

UP000218220    UP000192223    UP000007266    UP000007151    UP000007819    UP000069940    + More
UP000249989    UP000283053    UP000053268    UP000008820    UP000037510    UP000019118    UP000005203    UP000235965    UP000245037    UP000053097    UP000279307    UP000094527    UP000079169    UP000076858    UP000000305    UP000053825    UP000198287    UP000027135    UP000002320   

PRIDE

G9LPV9    G9LPV6   

Pfam

PF00201   UDPGT

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       
IPR018506   Cyt_B5_heme-BS       

ProteinModelPortal

A0A2H1VU07   G9LPR8   A0A2A4JI28   V5H2B2   A0A2H8TIZ0   A0A1Y1LMI4   + More
A0A1Y1LL43   A0A1Y1LIT5   A0A2H4WB74   A0A1L8D6F8   A0A1W4WYE4   A0A1W4WMF1   A0A1W4WMC9   D2A2V5   A0A286MXP5   A0A1W4WY61   A0A139WIW7   A0A212EWF8   S4PCR1   A0A191T1N3   A0A286MXP6   G9LPP9   G9LPR5   A0A2S2PC03   A0A2H8TVS6   A0A2D1GSK6   V9IL65   A0A2A4JHL4   J9KB24   A0A1W7R8H2   J9K7F3   A0A182GYX7   A0A2D1GSG4   A0A1B6KVV9   A0A2H1W091   A0A3S2PBM0   A0A2D1GSL9   A0A1B6L8F2   A0A1B6FW51   A0A194PN21   A0A1B6KXR8   A0A1B6F5J1   A0A2R4FXJ3   Q17KZ7   A0A2H1W5A1   A0A2S2P7P3   G9LPV9   A0A2S2NP66   A0A2A4K0B3   A0A1S4EZ13   G9LPV6   A0A0L7L3K3   N6UB74   A0A087ZYR9   J3JVI3   A0A191T1L9   A0A2D1GSI9   A0A0P5JI56   A0A2D1GSF6   A0A2J7R4T0   A0A2P8ZG78   A0A3S2N8S7   A0A336LTZ6   A0A2H8TXR1   A0A026WYL1   A0A3L8DPI9   A0A2S2R018   A0A2D1GSM0   A0A1D2MYE5   A0A1S3CYB2   A0A194PHJ2   X1WIH9   A0A0P5D4L6   A0A162P1L4   A0A1D2NEE8   A0A0P6E0N5   A0A0N8CHL9   A0A194PIG8   A0A2P8ZG70   E9HIB8   V5GU86   A0A0P5VPG3   A0A2J7R4W0   A0A0N8DAL2   A0A0L7RH14   A0A226DZS8   A0A023R9H7   A0A2H1VD70   A0A067RAP7   B0VZV7   A0A023R6Z5   A0A2H8TRY0   A0A2J7R4W5   A0A191T1P6   G9LPR3   N6UH99   A0A1B6E1B5   A0A1B6DPF5   A0A1B6DAQ2   A0A1B6CCZ4  

PDB

2O6L     E-value=1.32845e-13,     Score=181

KEGG

100862822    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT46C2; UDP-glucuronosyltransferase 2B7

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016758   GO:0016021   GO:0015020   GO:0020037   GO:0008194   GO:0043231   GO:0016757   GO:0008152   GO:0004553   GO:0042600   GO:0006811   GO:0005509   GO:0016042   GO:0016020   GO:0003707   GO:0051537  

Subcellular location

Membrane  

Length:

203

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

12.59283

Exp number, first 60 AAs:

0.80132

Total prob of N-in:

0.38321

outside

1  -  203

 

 

Pi

2.558615

Theta

5.36592

Tajima's D

-1.986158

CLR

14.853209

CSRT

0.0105494725263737

Interpretation

Uncertain