Gene

KWMTBOMO07504  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005878

Annotation

PREDICTED:_transcription_initiation_factor_IIE_subunit_beta_[Papilio_xuthus]

Location

Bomo_Chr12(+):15218708-15222775      View in EpiBrowser

Full name

Transcription initiation factor IIE subunit beta      

Location in the cell

Nuclear   Reliability : 4.566

CDS

ATGGACCCGGCGCTCTTACGGGAACGGGAAGCGTTTAAAAAGAAGGCACTTGCGACCCCGAGCATTGAAAAAAAGAAAAGGGATGACTCTGAATTCAAAGATGACAGCAAAAAGAAATCGAAATCATCCAGCTCAGTCAGCTCCGGACCAAAGCTTGATGCTAGTAATTACAAGACTATGACTGGCAGCTCGTCCTATCGCTTTGGTGTGCTAGCGCGTATTGTACGGCATATGAGAGCAAGGCATCAAGATGGAGATGACCATCCACTGTCTTTAGATGAGATTTTAGATGAGACAAATCAATTGGATGTCGGAAATAAAATAAAACAGTGGCTACAAACAGAAGCCCTACAGAGCAATCCTAAAATCGAATGCTCTCCGGATGGAAAGTTTAACTTCAAACCGGTTTATAAAATAAAAGATAAAAAATCTTTACTGAGGTTACTTAAGCAACAAGACCTCAAAGGCTTGGGAGGTATATTATTGGAAGATGTTCAAGAGTCGCTGCCTCACTGCGAGAGAGCACTGAAACATTTGGCACAAGAGATTTTGTATATAACAAGGCACACTGATAAAAAGAAAATATTATTCTACAATGATAAGACTGCTACATTAGACGTAGATGACGAATTCGTGAAATTATGGCGTGCAACAGCGGTGGACGCGATGGACGACGCGAAGATCGAGGAGTACCTCGAGAAGCAAGGGATCAAATCCATGCAGGATCACGGGCCAAAGAAGATGCTTGCTCCCAAACGGAAGAAGGCCAAGCAGAAGCGTAGACAGTTCAAGAAACCAAGAGACAATGAACATTTGGCCCACGTACTGGAGACGTACGAGGATAACACGCTGACTCAGCAAGGAGTTTCCATTAAATAA

Protein

MDPALLREREAFKKKALATPSIEKKKRDDSEFKDDSKKKSKSSSSVSSGPKLDASNYKTMTGSSSYRFGVLARIVRHMRARHQDGDDHPLSLDEILDETNQLDVGNKIKQWLQTEALQSNPKIECSPDGKFNFKPVYKIKDKKSLLRLLKQQDLKGLGGILLEDVQESLPHCERALKHLAQEILYITRHTDKKKILFYNDKTATLDVDDEFVKLWRATAVDAMDDAKIEEYLEKQGIKSMQDHGPKKMLAPKRKKAKQKRRQFKKPRDNEHLAHVLETYEDNTLTQQGVSIK

Description

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

Subunit

Tetramer of two alpha and two beta chains.

Similarity

Belongs to the TFIIE beta subunit family.

Uniprot

H9J8N6   A0A2A4JI13   A0A1E1WHF1   A0A0N1IFX0   S4PY18   A0A2H1V2R2   + More
A0A212EK30   A0A194PU71   U5EUM5   B0X433   A0A1Q3FA59   A0A0A1XM27   B4L9A3   B4LBQ9   A0A182KW59   A0A182XCZ9   Q7Q7C7   A0A182IKD0   A0A0K8W5D1   T1PH62   W8BZ93   A0A1L8DH07   A0A182UXT4   A0A182HMC7   A0A182R2N9   A0A182SB97   A0A182LZD4   A0A182QG40   A0A182N7T1   A0A034WLD0   A0A084WEU4   A0A182YNP2   W5JAL9   A0A0L0CLB8   A0A023EMR2   A0A182KAI9   A0A182WAN9   A0A2M3Z8F2   A0A2M4AQS9   A0A182FFQ2   A0A2M4BVN0   A0A182H2L8   A0A1I8Q164   A0A1W4VUN4   B4J1I0   A0A182GLZ8   Q29EG4   B4PHT7   A0A182PUU5   B4H1Z4   J3JWI6   B3M909   A0A3B0J9U2   A0A0K8TR33   B4NLY6   A0A1S4FTA4   Q16Q16   B3NC19   O96881   B4HU43   B4QQJ7   D6WSM2   D3TNI3   A0A2H1VAM8   A0A0L7LBA6   A0A1Y1N4G3   A0A2A3EJN2   A0A1B0AR63   A0A2J7QNS9   A0A1A9XGS6   A0A154P2S5   A0A0M4EYZ6   F4WUG3   A0A151XFP8   A0A195BDD9   A0A158NFE3   A0A151JZH5   A0A2P8YW15   A0A195D6U3   A0A0L7R9I5   A0A336LHH7   E2BF31   A0A0J7KPL3   E0VXJ2   E9IJ90   E2A6B3   A0A087ZQE1   A0A1B0CBT6   A0A026WHK3   A0A1B6GPV1   A0A232FF13   A0A1B6HZY4   K7JAG0   A0A1B6DGD1   A0A0A9Y5A9   A0A1B0FRJ7   A0A069DYD8   A0A182UI79   A0A0N0BEF6   A0A1A9ZG27  

Pubmed

19121390    26354079    23622113    22118469    25830018    17994087    + More
20966253    12364791    14747013    17210077    25315136    24495485    25348373    24438588    25244985    20920257    23761445    26108605    24945155    26483478    15632085    17550304    22516182    23537049    26369729    17510324    9012800    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    22936249    18362917    19820115    20353571    26227816    28004739    21719571    21347285    29403074    20798317    20566863    21282665    24508170    30249741    28648823    20075255    25401762    26823975    26334808   

EMBL

BABH01030376    NWSH01001496    PCG71073.1    GDQN01004718    JAT86336.1    KQ460954    + More
KPJ10250.1    GAIX01004063    JAA88497.1    ODYU01000407    SOQ35135.1    AGBW02014349    OWR41830.1    KQ459592    KPI96867.1    GANO01001402    JAB58469.1    DS232327    EDS40110.1    GFDL01010605    JAV24440.1    GBXI01002377    JAD11915.1    CH933816    EDW17278.1    CH940647    EDW68686.1    AAAB01008960    EAA11794.3    GDHF01005901    JAI46413.1    KA648111    AFP62740.1    GAMC01001923    JAC04633.1    GFDF01008417    JAV05667.1    APCN01004405    AXCM01002989    AXCN02000586    GAKP01004374    JAC54578.1    ATLV01023258    KE525341    KFB48738.1    ADMH02001932    ETN60443.1    JRES01000240    KNC33041.1    GAPW01002956    JAC10642.1    GGFM01004053    MBW24804.1    GGFK01009826    MBW43147.1    GGFJ01007911    MBW57052.1    JXUM01105523    KQ564973    KXJ71485.1    CH916366    EDV95871.1    JXUM01073321    KQ562767    KXJ75165.1    CH379070    EAL30097.1    CM000159    EDW93396.1    CH479203    EDW30346.1    APGK01010618    APGK01017343    BT127604    KB740012    KB738240    KB631654    AEE62566.1    ENN81901.1    ENN82710.1    ERL85053.1    CH902618    EDV38953.1    OUUW01000002    SPP77163.1    GDAI01000766    JAI16837.1    CH964278    EDW85354.1    CH477766    EAT36460.1    CH954178    EDV50907.1    U72893    AE014296    BT022197    AAD00188.1    AAF47880.1    AAY51591.1    CH480817    EDW50464.1    CM000363    CM002912    EDX09203.1    KMY97561.1    KQ971354    EFA05897.1    EZ422985    ADD19261.1    ODYU01001544    SOQ37910.1    JTDY01001830    KOB72772.1    GEZM01013039    JAV92801.1    KZ288223    PBC32023.1    JXJN01002265    NEVH01012562    PNF30239.1    KQ434795    KZC05528.1    CP012525    ALC43520.1    GL888365    EGI62128.1    KQ982182    KYQ59161.1    KQ976514    KYM82219.1    ADTU01014356    KQ981410    KYN41895.1    PYGN01000327    PSN48446.1    KQ976750    KYN08615.1    KQ414627    KOC67416.1    UFQS01004045    UFQT01004045    SSX16125.1    SSX35452.1    GL447910    EFN85709.1    LBMM01004552    KMQ92298.1    DS235832    EEB18098.1    GL763739    EFZ19357.1    GL437123    EFN70998.1    AJWK01005820    KK107199    QOIP01000009    EZA55542.1    RLU18968.1    GECZ01005318    JAS64451.1    NNAY01000303    OXU29351.1    GECU01027521    GECU01000504    JAS80185.1    JAT07203.1    GEDC01012547    JAS24751.1    GBHO01016245    GDHC01009495    GDHC01008261    JAG27359.1    JAQ09134.1    JAQ10368.1    CCAG010014067    GBGD01002455    JAC86434.1    KQ435828    KOX71842.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000007151    UP000053268    UP000002320    + More
UP000009192    UP000008792    UP000075882    UP000076407    UP000007062    UP000075880    UP000095301    UP000075903    UP000075840    UP000075900    UP000075901    UP000075883    UP000075886    UP000075884    UP000030765    UP000076408    UP000000673    UP000037069    UP000075881    UP000075920    UP000069272    UP000069940    UP000249989    UP000095300    UP000192221    UP000001070    UP000001819    UP000002282    UP000075885    UP000008744    UP000019118    UP000030742    UP000007801    UP000268350    UP000007798    UP000008820    UP000008711    UP000000803    UP000001292    UP000000304    UP000007266    UP000037510    UP000242457    UP000092460    UP000235965    UP000092443    UP000076502    UP000092553    UP000007755    UP000075809    UP000078540    UP000005205    UP000078541    UP000245037    UP000078542    UP000053825    UP000008237    UP000036403    UP000009046    UP000000311    UP000005203    UP000092461    UP000053097    UP000279307    UP000215335    UP000002358    UP000092444    UP000075902    UP000053105    UP000092445   

PRIDE

H9J8N6    O96881   

Pfam

PF18121   TFA2_Winged_2        + More
PF02186   TFIIE_beta
PF00651   BTB
PF00728   Glyco_hydro_20
PF14845   Glycohydro_20b2

Interpro

IPR016656   TFIIE-bsu        + More
IPR040501   TFA2_Winged_2       
IPR036388   WH-like_DNA-bd_sf       
IPR036390   WH_DNA-bd_sf       
IPR003166   TFIIE_bsu_DNA-bd       
IPR000210   BTB/POZ_dom       
IPR011333   SKP1/BTB/POZ_sf       
IPR029019   HEX_eukaryotic_N       
IPR015883   Glyco_hydro_20_cat       
IPR029018   Hex-like_dom2       
IPR017853   Glycoside_hydrolase_SF       
IPR025705   Beta_hexosaminidase_sua/sub       

SUPFAM

SSF46785   SSF46785        + More
SSF54695   SSF54695       
SSF55545   SSF55545       
SSF51445   SSF51445       

Gene 3D

1.10.10.10     3.30.379.10    

CDD

cd07977  TFIIE_beta_winged_helix

ProteinModelPortal

H9J8N6   A0A2A4JI13   A0A1E1WHF1   A0A0N1IFX0   S4PY18   A0A2H1V2R2   + More
A0A212EK30   A0A194PU71   U5EUM5   B0X433   A0A1Q3FA59   A0A0A1XM27   B4L9A3   B4LBQ9   A0A182KW59   A0A182XCZ9   Q7Q7C7   A0A182IKD0   A0A0K8W5D1   T1PH62   W8BZ93   A0A1L8DH07   A0A182UXT4   A0A182HMC7   A0A182R2N9   A0A182SB97   A0A182LZD4   A0A182QG40   A0A182N7T1   A0A034WLD0   A0A084WEU4   A0A182YNP2   W5JAL9   A0A0L0CLB8   A0A023EMR2   A0A182KAI9   A0A182WAN9   A0A2M3Z8F2   A0A2M4AQS9   A0A182FFQ2   A0A2M4BVN0   A0A182H2L8   A0A1I8Q164   A0A1W4VUN4   B4J1I0   A0A182GLZ8   Q29EG4   B4PHT7   A0A182PUU5   B4H1Z4   J3JWI6   B3M909   A0A3B0J9U2   A0A0K8TR33   B4NLY6   A0A1S4FTA4   Q16Q16   B3NC19   O96881   B4HU43   B4QQJ7   D6WSM2   D3TNI3   A0A2H1VAM8   A0A0L7LBA6   A0A1Y1N4G3   A0A2A3EJN2   A0A1B0AR63   A0A2J7QNS9   A0A1A9XGS6   A0A154P2S5   A0A0M4EYZ6   F4WUG3   A0A151XFP8   A0A195BDD9   A0A158NFE3   A0A151JZH5   A0A2P8YW15   A0A195D6U3   A0A0L7R9I5   A0A336LHH7   E2BF31   A0A0J7KPL3   E0VXJ2   E9IJ90   E2A6B3   A0A087ZQE1   A0A1B0CBT6   A0A026WHK3   A0A1B6GPV1   A0A232FF13   A0A1B6HZY4   K7JAG0   A0A1B6DGD1   A0A0A9Y5A9   A0A1B0FRJ7   A0A069DYD8   A0A182UI79   A0A0N0BEF6   A0A1A9ZG27  

PDB

6O9L     E-value=2.46158e-57,     Score=561

KEGG

101742930    K03137 transcription initiation factor TFIIE subunit beta | (RefSeq) general transcription factor II

PATHWAY

03022    Basal transcription factors - Bombyx mori (domestic silkworm)

GO

GO:0006367   GO:0005673   GO:0003677   GO:0003743   GO:0045944   GO:0005634   GO:0016021   GO:0004563   GO:0005975   GO:0004553   GO:0042600   GO:0006811   GO:0005509   GO:0016042   GO:0016020   GO:0003707   GO:0051537  

PANTHER

PTHR12716  

Subcellular location

Nucleus  

Length:

292

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00036

Exp number, first 60 AAs:

9e-05

Total prob of N-in:

0.01758

outside

1  -  292

 

 

Pi

20.741146

Theta

19.949439

Tajima's D

0.423513

CLR

0.5725

CSRT

0.497025148742563

Interpretation

Uncertain