Gene

KWMTBOMO07501  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005899

Annotation

PREDICTED:_chitooligosaccharidolytic_beta-N-acetylglucosaminidase_isoform_X1_[Bombyx_mori]

Location

Bomo_Chr12(-):15174332-15195228      View in EpiBrowser

Full name

Chitooligosaccharidolytic beta-N-acetylglucosaminidase       + More
Beta-hexosaminidase      

Alternative Name

Beta-GlcNAcase
Beta-N-acetylhexosaminidase
Beta-hexosaminidase

Location in the cell

Cytoplasmic   Reliability : 1.389

CDS

ATGAGAAAACTCAATGAGCAATCATATAAAAATGACAGATTCCAAATTCAAATTCCGACGGCAGCCGAAGAGCACTCATTGTGGAGATGGACGTGCGAAAACAATAGATGCACGAAGATCAGGAACGAGCCGGAGAATAAAGAGCCTGTCCTCAGTCTGGAAGCATGCAAGATGTTCTGTGACGATTACGGTCTCCTCTGGCCGAAACCAACGATCGAGACAAATCTGGGTAACTTCCTCTCCAAGATTAATATGAACACCATCGACATTCAGATCACCAAGCAGGGAAAGAGCGACGACCTCCTCACAGCGGCTGCCGACAGATTTAAGACACTGGTTTCCAGTTCCGTGCCAAAAGGCTTCTCGGCGAAGGCTGCAGGAAAATCAGTCACAGTTTATTTAGTCAATGACAATCCTTATATCCGAGAATTCTCCCTGGACATGGATGAGAGCTACGAGCTCTACATTTCATCAACGTCGAGCGACAAAGTGAACGCTACCATACGTGGAAACTCTTTCTTCGGCGTCCGTCACGGTCTGGAGACGCTCTCTCAGCTAATCGTGTACGACGACATAAGGAATAATCTGTTGATTGTCCGTGACGTCACAATTAAGGACAGGCCTGTCTATCCTTATCGAGGTATTTTGTTGGACACCGCGAGGAACTTCTACTCCATAGAATCAATCAAAAGAACTATAGACGCAATGGCCGCAGTGAAACTGAACACATTCCACTGGCACATCACGGACAGCCAGAGTTTCCCGTTGGTGTTACAGAAAAGACCGAACTTGAGTAAGCTCGGGGCATACAGTCCCACCAAGGTGTACACAAAGCAAGATATTCGTGAAGTTGTCGCATATGGTCTAGAGAGGGGAGTTCGTGTTTTACCGGAATTTGATGCGCCTGCTCATGTGGGAGAGGGATGGCAGGACACTGGACTCACCGTGTGCTTTAAGGCGGAGCCGTGGACGAAATTCTGCGTGGAGCCGCCTTGTGGTCAGCTGAACCCGACTAAAGAGGAACTTTACGACTATTTGGAAGATATTTACGTTGAAATGGCTGAGGCGTTTGAGAGCACCGACATGTTCCACATGGGAGGAGACGAGGTCAGCGAACGCTGTTGGAACTCCTCAGAGGAGATCCAGAACTTTATGATTCAAAACCGATGGAATTTGGACAAGAGCAGTTTCTTGAAGCTTTGGAACTACTTCCAGAAGAACGCTCAAGACAGAGCGTATAAGGCCTTCGGTAAACGACTGCCTCTGATTCTATGGACCAGCACATTGACCGACTACACTCACGTAGAGAAATTCTTGGACAAAGACGAATACATCATACAGGTCTGGACCACGGGAGCCGACCCACAAATTCAAGGTTTACTCCAGAAAGGATATCGCCTGATTATGTCAAATTATGACGCTCTGTACTTTGACTGTGGATTCGGGGCATGGGTTGGGTCCGGCAATAATTGGTGCTCACCGTACATCGGGTGGCAGAAAGTGTATGGTAACAGTCCAGCGGTGATGGCGCTCTCGTACCGAGATCAGATCTTGGGTGGTGAAGTAGCGCTGTGGTCCGAGCAGTCAGACCCTGCCACGCTGGACGGCCGACTGTGGCCCAGAGCGGCTGCCTTCGCCGAGCGCATGTGGGCCGAACCTTCCACCGCGTGGCAGGACGCCGAGCACCGGATGCTCCATGTCAGAGAACGTTTGGTAAGAATGGGAATTCAAGCTGAATCGCTTGAGCCGGAGTGGTGCTATCAGAATCAAGGACTTTGCTATGGTTAG

Protein

MRKLNEQSYKNDRFQIQIPTAAEEHSLWRWTCENNRCTKIRNEPENKEPVLSLEACKMFCDDYGLLWPKPTIETNLGNFLSKINMNTIDIQITKQGKSDDLLTAAADRFKTLVSSSVPKGFSAKAAGKSVTVYLVNDNPYIREFSLDMDESYELYISSTSSDKVNATIRGNSFFGVRHGLETLSQLIVYDDIRNNLLIVRDVTIKDRPVYPYRGILLDTARNFYSIESIKRTIDAMAAVKLNTFHWHITDSQSFPLVLQKRPNLSKLGAYSPTKVYTKQDIREVVAYGLERGVRVLPEFDAPAHVGEGWQDTGLTVCFKAEPWTKFCVEPPCGQLNPTKEELYDYLEDIYVEMAEAFESTDMFHMGGDEVSERCWNSSEEIQNFMIQNRWNLDKSSFLKLWNYFQKNAQDRAYKAFGKRLPLILWTSTLTDYTHVEKFLDKDEYIIQVWTTGADPQIQGLLQKGYRLIMSNYDALYFDCGFGAWVGSGNNWCSPYIGWQKVYGNSPAVMALSYRDQILGGEVALWSEQSDPATLDGRLWPRAAAFAERMWAEPSTAWQDAEHRMLHVRERLVRMGIQAESLEPEWCYQNQGLCYG

Catalytic Activity

Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.

Similarity

Belongs to the glycosyl hydrolase 20 family.

Keywords

Carbohydrate metabolism   Chitin degradation   Complete proteome   Direct protein sequencing   Glycoprotein   Glycosidase   Hydrolase   Polysaccharide degradation   Reference proteome   Signal  

Feature

chain  Chitooligosaccharidolytic beta-N-acetylglucosaminidase

Uniprot

P49010   Q9GPG8   H9J8Q7   Q6UJX7   A0A2A4JK08   Q06GJ0   + More
A0A0K0Q482   Q8T4N1   A0A218N0E0   D6PX67   Q52H16   A0A194PTX4   A0A0N1INV6   R4X5G1   C5IBZ5   A0A0F6PA61   A0A0L7LJ05   Q0MUV1   A0A3G1VUC7   A0A0T6BFY9   A0A0K8TL07   D6WPS5   A5YVX3   A0A1Y1MFL2   A0A3G5BIK2   A0A336MGX8   A0A182HB96   A0A1S4F898   Q17C82   A0A1J1IDP2   A0A1Y1MFQ5   A0A1Y1MF42   W8C231   T1PGB1   A0A182PUU4   A0A182WAN8   A0A182XD00   A0A0A1WSJ6   B4NLY5   A0A182M4F8   B4PHT8   A0A182KW66   A0A0L0CQ06   W8C2W8   A0A0K8U2M5   A0A182VK01   Q7Q7C8   A0A0R1E1S0   A0A182TF75   A0A0K8V7G3   A0A182HMC8   A0A084WEU5   B4LBR0   A0A0K8W4A2   A0A034VMN1   A0A182KAJ0   A0A0A1WY49   A0A0K8WHW6   A0A1W4VUL9   B4L9A2   A0A1W4W769   A0A2P0P9I9   A0A182SF49   A0A0K8VUH2   B4H1Z3   A0A0J9UEF6   Q0E8H9   Q8IRB6   A0A0J9RNW8   A0A182R2N8   B3M910   Q29EG3   B4HU44   B0X434   Q8MSS9   A0A067RD91   A0A2J7Q7A7   B4QQJ8   A0A182H8G3   A0A034VP89   A0A0A1WVT1   B4J1I1   A0A182N7T2   A0A182YNP1   K7J7Q3   A0A1W4XGX0   A0A3B0JAY0   A0A0K8VWT2   B3NC20   A0A0Q5UI80   A0A1L8E1Y0   A0A2M4DMQ0   A0A2M4DNW7   T1EAY4   A0A1L8E1N2   A0A182QJN0   A0A1A9WD41   A0A182FFQ0   A0A0M4ED89  

EC Number

3.2.1.52

Pubmed

7766021    19121390    8763162    18959754    21692744    21106526    + More
23300622    25155420    30135205    18330895    26354079    26227816    26369729    18362917    19820115    18342252    28004739    30400621    26483478    17510324    24495485    25315136    25830018    17994087    17550304    20966253    26108605    12364791    14747013    17210077    24438588    25348373    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    18057021    15632085    24845553    25244985    20075255   

EMBL

S77548    AF326597    AAG48701.1    BABH01030382    BABH01030383    BABH01030384    + More
BABH01030385    BABH01030386    AY368703    AAQ97603.1    NWSH01001195    PCG72159.1    DQ887769    ABI81756.1    KP730442    AKR06190.1    AY078172    AAL82580.1    KY348777    ASF79655.1    GU985280    ADF56765.1    DQ005717    AAX94571.1    KQ459592    KPI96866.1    KQ460954    KPJ10249.1    AB766061    BAN29056.1    FJ848784    ACR57832.1    KJ632673    AJF93429.1    JTDY01000943    KOB75344.1    DQ845101    ABH09730.1    MH027208    AYK27452.1    LJIG01001141    KRT85799.1    GDAI01002541    JAI15062.1    KQ971354    EFA06863.2    EF592536    ABQ95982.1    GEZM01032380    GEZM01032379    JAV84619.1    MK075198    AYV99601.1    UFQT01001058    SSX28661.1    JXUM01124582    JXUM01124583    JXUM01124584    CH477311    EAT43909.1    CVRI01000047    CRK98399.1    GEZM01033085    JAV84421.1    GEZM01033084    JAV84422.1    GAMC01003317    JAC03239.1    KA646918    AFP61547.1    GBXI01012904    JAD01388.1    CH964278    EDW85353.2    AXCM01002989    CM000159    EDW93397.1    JRES01000080    KNC34346.1    GAMC01006349    JAC00207.1    GDHF01031593    JAI20721.1    AAAB01008960    EAA10994.4    KRK01159.1    GDHF01017447    JAI34867.1    APCN01004405    ATLV01023258    KE525341    KFB48739.1    CH940647    EDW68687.1    GDHF01006388    JAI45926.1    GAKP01014361    JAC44591.1    GBXI01010530    JAD03762.1    GDHF01001591    GDHF01001266    JAI50723.1    JAI51048.1    CH933816    EDW17277.2    KU739382    ARA90559.1    GDHF01010119    GDHF01007292    JAI42195.1    JAI45022.1    CH479203    EDW30345.1    CM002912    KMY97565.1    AE014296    AAF47881.1    BT099589    AAG22248.2    AAN11596.1    ACU43551.1    KMY97563.1    CH902618    EDV38954.2    KPU77762.1    CH379070    EAL30098.1    CH480817    EDW50465.1    DS232327    EDS40111.1    AY118626    AAM49995.1    KK852777    KDR16738.1    NEVH01017447    PNF24460.1    CM000363    EDX09204.1    JXUM01118347    JXUM01118348    GAKP01013831    JAC45121.1    GBXI01011118    JAD03174.1    CH916366    EDV95872.1    AAZX01006692    OUUW01000002    SPP77162.1    GDHF01009289    JAI43025.1    CH954178    EDV50908.1    KQS43574.1    GFDF01001445    JAV12639.1    GGFL01014631    MBW78809.1    GGFL01014630    MBW78808.1    GAMD01000643    JAB00948.1    GFDF01001444    JAV12640.1    AXCN02000586    CP012525    ALC43521.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000037510    UP000007266    + More
UP000069940    UP000008820    UP000183832    UP000095301    UP000075885    UP000075920    UP000076407    UP000007798    UP000075883    UP000002282    UP000075882    UP000037069    UP000075903    UP000007062    UP000075902    UP000075840    UP000030765    UP000008792    UP000075881    UP000192221    UP000009192    UP000075901    UP000008744    UP000000803    UP000075900    UP000007801    UP000001819    UP000001292    UP000002320    UP000027135    UP000235965    UP000000304    UP000001070    UP000075884    UP000076408    UP000002358    UP000192223    UP000268350    UP000008711    UP000075886    UP000091820    UP000069272    UP000092553   

PRIDE

P49010    H9J8Q7    Q0E8H9    Q8IRB6    Q8MSS9   

Pfam

PF14845   Glycohydro_20b2        + More
PF00728   Glyco_hydro_20
PF01504   PIP5K

Interpro

IPR029018   Hex-like_dom2        + More
IPR017853   Glycoside_hydrolase_SF       
IPR025705   Beta_hexosaminidase_sua/sub       
IPR029019   HEX_eukaryotic_N       
IPR015883   Glyco_hydro_20_cat       
IPR027483   PInositol-4-P-5-kinase_C       
IPR002498   PInositol-4-P-5-kinase_core       
IPR036390   WH_DNA-bd_sf       
IPR036388   WH-like_DNA-bd_sf       
IPR003166   TFIIE_bsu_DNA-bd       
IPR027484   PInositol-4-P-5-kinase_N       

SUPFAM

SSF55545   SSF55545        + More
SSF51445   SSF51445       
SSF46785   SSF46785       

Gene 3D

3.30.379.10     1.10.10.10     3.30.800.10     3.30.810.10    

CDD

cd07977  TFIIE_beta_winged_helix

ProteinModelPortal

P49010   Q9GPG8   H9J8Q7   Q6UJX7   A0A2A4JK08   Q06GJ0   + More
A0A0K0Q482   Q8T4N1   A0A218N0E0   D6PX67   Q52H16   A0A194PTX4   A0A0N1INV6   R4X5G1   C5IBZ5   A0A0F6PA61   A0A0L7LJ05   Q0MUV1   A0A3G1VUC7   A0A0T6BFY9   A0A0K8TL07   D6WPS5   A5YVX3   A0A1Y1MFL2   A0A3G5BIK2   A0A336MGX8   A0A182HB96   A0A1S4F898   Q17C82   A0A1J1IDP2   A0A1Y1MFQ5   A0A1Y1MF42   W8C231   T1PGB1   A0A182PUU4   A0A182WAN8   A0A182XD00   A0A0A1WSJ6   B4NLY5   A0A182M4F8   B4PHT8   A0A182KW66   A0A0L0CQ06   W8C2W8   A0A0K8U2M5   A0A182VK01   Q7Q7C8   A0A0R1E1S0   A0A182TF75   A0A0K8V7G3   A0A182HMC8   A0A084WEU5   B4LBR0   A0A0K8W4A2   A0A034VMN1   A0A182KAJ0   A0A0A1WY49   A0A0K8WHW6   A0A1W4VUL9   B4L9A2   A0A1W4W769   A0A2P0P9I9   A0A182SF49   A0A0K8VUH2   B4H1Z3   A0A0J9UEF6   Q0E8H9   Q8IRB6   A0A0J9RNW8   A0A182R2N8   B3M910   Q29EG3   B4HU44   B0X434   Q8MSS9   A0A067RD91   A0A2J7Q7A7   B4QQJ8   A0A182H8G3   A0A034VP89   A0A0A1WVT1   B4J1I1   A0A182N7T2   A0A182YNP1   K7J7Q3   A0A1W4XGX0   A0A3B0JAY0   A0A0K8VWT2   B3NC20   A0A0Q5UI80   A0A1L8E1Y0   A0A2M4DMQ0   A0A2M4DNW7   T1EAY4   A0A1L8E1N2   A0A182QJN0   A0A1A9WD41   A0A182FFQ0   A0A0M4ED89  

PDB

3S6T     E-value=0,     Score=2489

KEGG

693032    K12373 hexosaminidase [EC:3.2.1.52] | (RefSeq) chitooligosaccharidolytic beta-N-acetylglucosaminidas

PATHWAY

00511    Other glycan degradation - Bombyx mori (domestic silkworm)
00520    Amino sugar and nucleotide sugar metabolism - Bombyx mori (domestic silkworm)
00531    Glycosaminoglycan degradation - Bombyx mori (domestic silkworm)
00603    Glycosphingolipid biosynthesis - globo and isoglobo series - Bombyx mori (domestic silkworm)
00604    Glycosphingolipid biosynthesis - ganglio series - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
04142    Lysosome - Bombyx mori (domestic silkworm)

GO

GO:0000272   GO:0004563   GO:0102148   GO:0006032   GO:0005975   GO:0008152   GO:0016021   GO:0006367   GO:0005524   GO:0016307   GO:0005886   GO:0006491   GO:0006517   GO:0016063   GO:0016231   GO:0008375   GO:0004553   GO:0042600   GO:0006811   GO:0005509   GO:0016042   GO:0016020   GO:0003707   GO:0051537  

Length:

595

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01601

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00342

outside

1  -  595

 

 

Pi

21.39565

Theta

21.589699

Tajima's D

-0.929023

CLR

0.862514

CSRT

0.151342432878356

Interpretation

Uncertain