Gene

KWMTBOMO07484

Pre Gene Modal

BGIBMGA005197

Annotation

PREDICTED:_mediator_of_RNA_polymerase_II_transcription_subunit_17_[Papilio_xuthus]

Location

Bomo_Chr12(+):14181313-14195988      View in EpiBrowser

Full name

Mediator of RNA polymerase II transcription subunit 17      

Alternative Name

Mediator complex subunit 17
dMED17
dTRAP80

Location in the cell

Nuclear   Reliability : 2.473

CDS

ATGGCAAATTCAGTGAACATATCGATAGAGGCACCTATAGAGAACCAAATACAGGAGATTACTTATGATGGGCAAGAGATTTATCAAGCACCTTTATCGATGTCAGAAAATCTGGCAAGACTAGCACAGAAGATAGATTTTTCAAAAACAGAAGATGAGTTCTGTAACATCAAGAAAGAAGGTGAAAGCAGTTCTGATACTAAATCAGATGAAGACAACAAAGACCAGAGCTACCAGTCCAGCTTATGGCCCTGGGACTCTGTTAGGAATAAGTTACGGAGTGCCTTGACTGAAGTTAGCGTTTTGGCGGATGTACTGAATATTGCTAAGGAGAAGAGGTATATGGTGCTTGACCCAGTCCAACCTGAAAAAGTTGAAAGTCGACCCATGGTTCAAGTCTACGGACGGAAGAAGGCACTGAGCGCCGCCGCTGCCGTCCTTCAAGCCGGCATGGAACGTCTCCGGGCCAGCGAGACCATGAGGATGGCGCGGAACATGCCAGATTTTCACATAGACTTGCTTAGGTTACGTCAAAATTGGAGGCTGAAGAAAGTTTCTAATACAATCATTGGTGATTTGAGCTACAGAACTGCTGGTTCTAAGTTCAGTCAGACGGGTGTGTTTGAGGTAACAAAAGCGCCCGAGGAGCAGATAGCTCAAGCGATGAGCATGAACACAGGAGGTCCCCCGCCCTCCGCCCTGCGCGTCACCGTCCCGCCAGAACTGCAGGGCGTCGCCTTCATATCCGTCCTTTGTCAGAAAGAACAGGAAGAAGTAGTGACTGCAACGTTGAGTGCTTCTGCGTTGAGCTGCACCGCAGGCGAGGGCGAGCTGCACTGGCAGCAGCGGCTGGAAGCGGCGCAGAACGTGCTGTTCTGCAAGGAGCTGTTTGCCAGACTGGCAGCCGAAGCCGTGCAGCTGGACGCCTCCATACCGCATATGGTTGTCGGGAATCAGATCATGGCCACAGTGCTGCCCGGCATCCAGTTGCTGATAGGACTCTGTCACAACAACGGACAGACCAACGCTAACGCGAATGTTGAGGGGGTTAAGACGGAGGGGTCCTCGTCGTCCGGCAAGTCTGACCACGACCACGTGCTGGAGCACTCGCTGCACCAGCTGCTGCGCGCCGTGCACCACGCCAACACGCACCACCCCTTCCCGCACCCCGCCACCGGACCCCTGGGGCCCTCCAAGCGACGCTGCCTCGCCGGTCCCATGGCGGCCGACCGCTACGAGCTCCTGGACATGAGCAAGGAGCAGTCCCTGCTGGAGCAGATCATACAGCAGGCCCAGCACTTCTTCATGAGGAGGAGAAGCGAATACGTGCTCGACACTATCGCTAAAGAGGTGAAGGATCCGTTGATAGTGTCGCACTGGAACGCGCTCAACAGTCCCACGCAGTCCTGCGTCAAGATAAACATCATGGCACACGGGTACGACGCGGTGTGCCGGACGTCGCTGGTGGTCCACGTCGGGGAGAAGACCTTGAAGTGCATCTGCAGGGACGGGAAGGTGCGGCACCTGTCCTACGAGCTGCAGGAGCTCAGGGACCTCATCTACTGTCAGATATACCAGCACCAGATGACGGCGGTGCAGGCGGTGGGGCGCTGCATGGGCTGGCAACTCCTGGCCAGCAGCGCGCACCTGGGCTCGGGGCCCGTGGAGCCGCTTGGGAACGCATCCTCCTGCCTACTCGCCTCGCCAAACGGAGACAGAATGATAGCAATAAGATGCGAGCCTTCTGTGGGAATTCAAGTGTTTATTGCTCAATCACCAAGAAAAGACTTTTTCTCGAGTGAACTAGTGCAAGACAAGAAGTGGGAGAATCTTGGAGGTGCCTTTAAAGAAATAAAATTAGACAAAATGGAGGGAAAGAACTTTTTAAACAAAATGGAGTTGCTTATGGCCTGTTTGAGCAGTCCTTCGTAA

Protein

MANSVNISIEAPIENQIQEITYDGQEIYQAPLSMSENLARLAQKIDFSKTEDEFCNIKKEGESSSDTKSDEDNKDQSYQSSLWPWDSVRNKLRSALTEVSVLADVLNIAKEKRYMVLDPVQPEKVESRPMVQVYGRKKALSAAAAVLQAGMERLRASETMRMARNMPDFHIDLLRLRQNWRLKKVSNTIIGDLSYRTAGSKFSQTGVFEVTKAPEEQIAQAMSMNTGGPPPSALRVTVPPELQGVAFISVLCQKEQEEVVTATLSASALSCTAGEGELHWQQRLEAAQNVLFCKELFARLAAEAVQLDASIPHMVVGNQIMATVLPGIQLLIGLCHNNGQTNANANVEGVKTEGSSSSGKSDHDHVLEHSLHQLLRAVHHANTHHPFPHPATGPLGPSKRRCLAGPMAADRYELLDMSKEQSLLEQIIQQAQHFFMRRRSEYVLDTIAKEVKDPLIVSHWNALNSPTQSCVKINIMAHGYDAVCRTSLVVHVGEKTLKCICRDGKVRHLSYELQELRDLIYCQIYQHQMTAVQAVGRCMGWQLLASSAHLGSGPVEPLGNASSCLLASPNGDRMIAIRCEPSVGIQVFIAQSPRKDFFSSELVQDKKWENLGGAFKEIKLDKMEGKNFLNKMELLMACLSSPS

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for activated transcription of the MtnA, MtnB and MtnD genes. Negatively regulates sex comb development.
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).

Subunit

Component of the Mediator complex.
Component of the Mediator complex, which includes at least CDK8, MED4, MED6, MED11, MED14, MED17, MED18, MED20, MED21, MED22, MED27, MED28, MED30 and MED31. Interacts with Hsf.

Similarity

Belongs to the Mediator complex subunit 17 family.

Keywords

Activator   Chromosome   Complete proteome   Developmental protein   Nucleus   Reference proteome   Transcription   Transcription regulation  

Feature

chain  Mediator of RNA polymerase II transcription subunit 17

Uniprot

H9J6Q5   A0A2A4JP96   A0A2H1V2W4   A0A212F6G9   A0A194PTW1   A0A154PAU9   + More
A0A088ADR2   A0A2A3EPW2   A0A026WB10   E2B843   A0A067QW77   A0A151I9E4   F4WSX7   A0A151J542   A0A195AYA7   A0A158NYE2   A0A0L7RGA6   A0A0M8ZRT4   A0A195F6J6   A0A0C9PXF0   E2ASD9   A0A1B6C683   D2A2J0   E0VP27   A0A1W4WS26   A0A1B6MQ02   A0A3Q0ITU9   A0A0A9XU91   A0A1Y1LM40   K7J1S7   A0A232F7S4   A0A0A9WMF7   A0A146MDW0   A0A023F504   A0A069DWK8   A0A0V0G9X6   A0A224X949   A0A2J7QYA2   A0A0T6B901   A0A2P8XMA7   U4U2N0   N6TLG2   T1IGK3   A0A2S2R5I5   A0A0J7L6J9   J9K7P2   A0A1B0CYG2   B4NB47   A0A1W4U891   W8BTP5   A0A034WKF9   A0A0K8TWR5   B3P0C9   A0A0A1XM20   Q293V0   B4GLL6   B4JUI1   B4LZ81   A0A0L0C2A8   A0A3B0KEH7   T1PM48   B4PL76   Q9VEC1   A0A1I8MKL7   B4IB96   B3M2U7   A0A1A9WJM0   B4KCC7   A0A1B0G6U7   A0A1B0AAC6   A0A084WC33   A0A1A9UN88   A0A182QGH6   A0A2S2P6B1   A0A1A9YK77   A0A182NF10   A0A1B0BBZ1   A0A182TQQ0   A0A182I531   Q7PVZ2   A0A182WYP0   A0A182VNK8   A0A182WH34   A0A182YCJ3   A0A182LV17   A0A182K8M3   A0A2M4AR81   A0A182SDY8   B0W1K2   A0A182RIY2   A0A1I8P0Q1   W5JGN5   A0A182IPB0   A0A0M4EQB1   T1JGQ6   Q17JT4   A0A2K7P686   A0A182KUJ5   A0A182F5C8   A0A182GW03  

Pubmed

19121390    22118469    26354079    24508170    30249741    20798317    + More
24845553    21719571    21347285    18362917    19820115    20566863    25401762    26823975    28004739    20075255    28648823    25474469    26334808    29403074    23537049    17994087    24495485    25348373    25830018    15632085    26108605    17550304    11090137    10731132    12537572    12537569    11511356    11259581    12021283    16751183    25315136    24438588    12364791    25244985    20920257    23761445    17510324    20966253    26483478   

EMBL

BABH01038119    BABH01038120    NWSH01000898    PCG73639.1    ODYU01000431    SOQ35185.1    + More
AGBW02010020    OWR49327.1    KQ459592    KPI96851.1    KQ434864    KZC08982.1    KZ288206    PBC33081.1    KK107295    QOIP01000003    EZA53118.1    RLU24324.1    GL446282    EFN88135.1    KK852886    KDR14366.1    KQ978296    KYM95363.1    GL888331    EGI62681.1    KQ980055    KYN17983.1    KQ976701    KYM77228.1    ADTU01003768    KQ414596    KOC70012.1    KQ435944    KOX68229.1    KQ981768    KYN36006.1    GBYB01006178    JAG75945.1    GL442298    EFN63605.1    GEDC01028285    JAS09013.1    KQ971338    EFA02017.1    AAZO01004081    DS235354    EEB15133.1    GEBQ01002018    JAT37959.1    GBHO01021141    GBRD01005609    GDHC01018387    GDHC01014862    JAG22463.1    JAG60212.1    JAQ00242.1    JAQ03767.1    GEZM01057963    JAV72067.1    NNAY01000817    OXU26347.1    GBHO01035936    JAG07668.1    GDHC01001010    JAQ17619.1    GBBI01002589    JAC16123.1    GBGD01000802    JAC88087.1    GECL01001281    JAP04843.1    GFTR01007571    JAW08855.1    NEVH01009108    PNF33567.1    LJIG01009123    KRT83710.1    PYGN01001734    PSN33125.1    KB631829    ERL86578.1    APGK01019788    KB740125    ENN81294.1    ACPB03019238    GGMS01016025    MBY85228.1    LBMM01000458    KMQ98286.1    ABLF02026328    AJVK01000146    CH964232    EDW81011.1    GAMC01001835    JAC04721.1    GAKP01002881    JAC56071.1    GDHF01033412    JAI18902.1    CH954181    EDV48644.1    GBXI01016882    GBXI01002387    JAC97409.1    JAD11905.1    CM000070    EAL29114.1    CH479185    EDW38440.1    CH916374    EDV91151.1    CH940650    EDW67088.1    JRES01001097    KNC25569.1    OUUW01000007    SPP83451.1    KA648968    AFP63597.1    CM000160    EDW95858.2    AF244916    AF289995    AE014297    AY118662    CH480827    EDW44654.1    CH902617    EDV43477.1    CH933806    EDW13736.1    CCAG010013874    ATLV01022552    KE525333    KFB47777.1    AXCN02000834    GGMR01012336    MBY24955.1    JXJN01011744    APCN01003774    AAAB01008984    AXCM01007899    GGFK01009959    MBW43280.1    DS231822    EDS25800.1    ADMH02001243    ETN63522.1    CP012526    ALC46485.1    JH432211    CH477230    JXUM01092226    KQ563971    KXJ73001.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000076502    UP000005203    + More
UP000242457    UP000053097    UP000279307    UP000008237    UP000027135    UP000078542    UP000007755    UP000078492    UP000078540    UP000005205    UP000053825    UP000053105    UP000078541    UP000000311    UP000007266    UP000009046    UP000192223    UP000079169    UP000002358    UP000215335    UP000235965    UP000245037    UP000030742    UP000019118    UP000015103    UP000036403    UP000007819    UP000092462    UP000007798    UP000192221    UP000008711    UP000001819    UP000008744    UP000001070    UP000008792    UP000037069    UP000268350    UP000002282    UP000000803    UP000095301    UP000001292    UP000007801    UP000091820    UP000009192    UP000092444    UP000092445    UP000030765    UP000078200    UP000075886    UP000092443    UP000075884    UP000092460    UP000075902    UP000075840    UP000007062    UP000076407    UP000075903    UP000075920    UP000076408    UP000075883    UP000075881    UP000075901    UP000002320    UP000075900    UP000095300    UP000000673    UP000075880    UP000092553    UP000008820    UP000075882    UP000069272    UP000069940    UP000249989   

PRIDE

H9J6Q5    Q9VEC1    Q7PVZ2   

Pfam

PF10156   Med17        + More
PF00147   Fibrinogen_C

Interpro

IPR019313   Mediator_Med17        + More
IPR002181   Fibrinogen_a/b/g_C_dom       
IPR036056   Fibrinogen-like_C       

SUPFAM

SSF56496   SSF56496       

ProteinModelPortal

H9J6Q5   A0A2A4JP96   A0A2H1V2W4   A0A212F6G9   A0A194PTW1   A0A154PAU9   + More
A0A088ADR2   A0A2A3EPW2   A0A026WB10   E2B843   A0A067QW77   A0A151I9E4   F4WSX7   A0A151J542   A0A195AYA7   A0A158NYE2   A0A0L7RGA6   A0A0M8ZRT4   A0A195F6J6   A0A0C9PXF0   E2ASD9   A0A1B6C683   D2A2J0   E0VP27   A0A1W4WS26   A0A1B6MQ02   A0A3Q0ITU9   A0A0A9XU91   A0A1Y1LM40   K7J1S7   A0A232F7S4   A0A0A9WMF7   A0A146MDW0   A0A023F504   A0A069DWK8   A0A0V0G9X6   A0A224X949   A0A2J7QYA2   A0A0T6B901   A0A2P8XMA7   U4U2N0   N6TLG2   T1IGK3   A0A2S2R5I5   A0A0J7L6J9   J9K7P2   A0A1B0CYG2   B4NB47   A0A1W4U891   W8BTP5   A0A034WKF9   A0A0K8TWR5   B3P0C9   A0A0A1XM20   Q293V0   B4GLL6   B4JUI1   B4LZ81   A0A0L0C2A8   A0A3B0KEH7   T1PM48   B4PL76   Q9VEC1   A0A1I8MKL7   B4IB96   B3M2U7   A0A1A9WJM0   B4KCC7   A0A1B0G6U7   A0A1B0AAC6   A0A084WC33   A0A1A9UN88   A0A182QGH6   A0A2S2P6B1   A0A1A9YK77   A0A182NF10   A0A1B0BBZ1   A0A182TQQ0   A0A182I531   Q7PVZ2   A0A182WYP0   A0A182VNK8   A0A182WH34   A0A182YCJ3   A0A182LV17   A0A182K8M3   A0A2M4AR81   A0A182SDY8   B0W1K2   A0A182RIY2   A0A1I8P0Q1   W5JGN5   A0A182IPB0   A0A0M4EQB1   T1JGQ6   Q17JT4   A0A2K7P686   A0A182KUJ5   A0A182F5C8   A0A182GW03  

KEGG

101739503    K15133 mediator of RNA polymerase II transcription subunit 17 | (RefSeq) mediator of RNA polymerase

GO

GO:0003712   GO:0006357   GO:0016592   GO:0070847   GO:0005634   GO:0003713   GO:0045498   GO:0031618   GO:0045944   GO:0033613   GO:0006366   GO:0009987   GO:0006367   GO:0016020   GO:0005216   GO:0006811   GO:0005509   GO:0016042   GO:0003707   GO:0051537  

PANTHER

PTHR13114  

Subcellular location

Nucleus  
Chromosome  

Length:

643

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01742

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00066

outside

1  -  643

 

 

Pi

22.735935

Theta

21.58837

Tajima's D

-0.666373

CLR

0.851728

CSRT

0.204889755512224

Interpretation

Uncertain