Gene

KWMTBOMO07450  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA005182

Annotation

PREDICTED:_alpha?alpha-trehalose-phosphate_synthase_[UDP-forming]_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr12(+):13714002-13727506      View in EpiBrowser

Full name

Serine/threonine-protein phosphatase      

Location in the cell

Cytoplasmic   Reliability : 2.017

CDS

ATGTTTCAGATAGTCCCCATTCGCGCGGAACCTAAACTCTTCGACAGCTACTACAATGGATGCTGTAACGGGACATTCTGGCCATTGTTTCATTCGATGCCAGACCGTGCCACTTTCATTGCTGACCACTGGAAGGCATATATCAAGATAAACGAGGAGTTTGCTGAGAAGACAGTCCACGCTCTCCATCTGCTGAACAAACAAAAGAAAGACAAAAATGGAAGTCCACCGATCGTGTGGGTTCACGACTACCATCTGATGTTGGCGGCTAATTGGATACGACAGAGAGCTGAAGAAGATGAGATTAAATGCAAGCTAGCATTCTTTCTGCACATACCGTTTCCACCGTGGGATATTTTTAGACTGTTCCCGTGGTCTGATGAAGTTTTGCAGGGAATTTTGGGTTGTGATATGGTGGGATTCCACATAGAGGATTACTGTTTGAATTTCATTGACTGCTGCCAAAGAAACTTGGGTTGCCGTGTCGATAGAAAAAATCTTCTGGTCGAACTGGGAGATCGCACCATCTGCGTGAGACCGCTACCGATCGGAGTGCCATACGAGAGATTCGTACAGCTGGCCCAAAACGCTAAGCCCGTGTTCTCTACAAGCCAAAAAGTGATATTAGGTGTTGATAGACTGGATTATACCAAAGGATTAGTGCATAGGTTGAAAGCTTTCGAGAGATTACTCGAGAAACACCCGGAGCATATCGAAAAGGTTGTTCTGCTCCAGATCTCGGTGCCCTCTAGGACAGATGTGAAGGAATACCAAGATCTGAAGGAGGAGATGGATCAGCTCGTTGGCAGGATCAATGGTCGATTTACAACGCCCAATTGGTCGCCGATAAGATATATTTACGGCTGCGTTGGTCAAGATGAGTTAGCGGCGTTTTATCGCGATGCTGCTGTGGCACTTGTAACTCCATTAAGAGACGGCATGAACCTGGTCGCGAAAGAGTTTGTGGCTTGTCAGATCAATAAGCCTCCTGGAGTATTAATAGTGTCGCCATTTGCTGGAGCAGGAGAAATGATGCACGAGGCTCTTATATGCAATCCTTATGAGCTCGACGATGCGGCCGAAGTCATTCATAGAGCCTTAATAATGCCAGAGGATGAACGGACAGTCCGCATGAACCACCTCAGGCGGAGGGAGCAGTTGAACGACGTGGACAGCTGGATGAAGGCGTTCCTCAAAGCGATGGACTCTCTGGAGGAAGAGGCCGACGACCTTGGAGCCACTACCATGCAACCAGTCACTATTGACGATTTCGATGAATATTTATCCAAGTACATCGGGTACACACAGAAGCTAGCCCTGCTGTTGGACTACGACGGTACCTTGGCCCCGATCGCGCCCCACCCGGACCTCGCCACGCTGCCTCTCGAGACCAAACACACCCTGCAGAGGCTCTCCAACATGTCCGATGTGTACATAGCCATCATATCGGGGAGGAACGTGGACAACGTCAAGCAAATGGTCGGTATCGAAGGCATCACGTATGCGGGTAACCACGGTCTGGAGATCTTACATCCTGACGGCAGCAAGTTTGTCCATCCAATGCCGATGGAGCTGCAAGACAAGGTCGTTGACCTGCTCAAATCACTGCAGGAGCAGGTATGCAAAGACGGAGCTTGGGTTGAGAACAAAGGAGCGTTGCTAACGTTCCACTACCGCGAGACTCCCGTGCCGAAGCGGGCCGCGCTGGCCGAGCAGGCCCGCAAGCTCATCACGGCCTCGGGCTTCACCCCGGCGCCGGCGCACTGCGCGCTGGAGGCGCGGCCCCCGGTGCAATGGGACAAAGGACGAGCTTCGATCTACATCTTGAGGACAGCATTCGGTTTGGACTGGAGCGAAAGGATCAGGATCATATACGCCGGTGACGACAACACCGACGAAGACGCTATGCTGGCTTTAAAAGGTATGGCTGCCACCTTCCGCATCGTATCATCGAACATCATAAAAACGTCGGCAGAACGACGTTTGTCCTCCACCGACTCTGTACTGGCGATGCTGAAGTGGGTCGAACGCCACTTCTCGAGACGCAAGCCCAGAGCGAATTCACTAACGTACAAGAACGCCAGGAAGGCCAGGGATACAATACAGATGCATATGTCATATCAAATGCCTTCGAAGACATCGCCCAGACACTCTCCCCCACATACTCCGGACAAAGGCTCAAGCGGCTCGGACTCGAGCTAA

Protein

MFQIVPIRAEPKLFDSYYNGCCNGTFWPLFHSMPDRATFIADHWKAYIKINEEFAEKTVHALHLLNKQKKDKNGSPPIVWVHDYHLMLAANWIRQRAEEDEIKCKLAFFLHIPFPPWDIFRLFPWSDEVLQGILGCDMVGFHIEDYCLNFIDCCQRNLGCRVDRKNLLVELGDRTICVRPLPIGVPYERFVQLAQNAKPVFSTSQKVILGVDRLDYTKGLVHRLKAFERLLEKHPEHIEKVVLLQISVPSRTDVKEYQDLKEEMDQLVGRINGRFTTPNWSPIRYIYGCVGQDELAAFYRDAAVALVTPLRDGMNLVAKEFVACQINKPPGVLIVSPFAGAGEMMHEALICNPYELDDAAEVIHRALIMPEDERTVRMNHLRRREQLNDVDSWMKAFLKAMDSLEEEADDLGATTMQPVTIDDFDEYLSKYIGYTQKLALLLDYDGTLAPIAPHPDLATLPLETKHTLQRLSNMSDVYIAIISGRNVDNVKQMVGIEGITYAGNHGLEILHPDGSKFVHPMPMELQDKVVDLLKSLQEQVCKDGAWVENKGALLTFHYRETPVPKRAALAEQARKLITASGFTPAPAHCALEARPPVQWDKGRASIYILRTAFGLDWSERIRIIYAGDDNTDEDAMLALKGMAATFRIVSSNIIKTSAERRLSSTDSVLAMLKWVERHFSRRKPRANSLTYKNARKARDTIQMHMSYQMPSKTSPRHSPPHTPDKGSSGSDSS

Catalytic Activity

H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate

Similarity

Belongs to the PPP phosphatase family.

Uniprot

H9J6P0   A0A2H1WFJ9   D2KHI8   A0A2A4ISC9   A0A194PU34   B5TD29   + More
A4GHG0   A0A2D0WL60   A0A0N1I975   A0A3G2SGU2   A0A2D3E2A0   A0A1J0M552   A0A2D3E238   S4NTI3   A0A212FF13   A0A1W6MPR2   J7G8S5   A0A310SSI4   V9IA83   K7IWD1   A0A0L7RFM2   A0A2A3EC11   A0A088A3B7   E2BI26   A0A151JTW4   A0A195EDF4   F4WQ53   A0A0C9RFD4   A0A158NX63   E2ANA9   A0A0C9QKI7   A0A026WD64   A0A151WYT2   A0A151I569   A0A0J7L2L4   A0A151I6N7   A0A1B0CHY7   A0A084W4K2   E0W3W6   A0A1Y0AWT0   A0A232F8Y6   A0A182J7Z1   A0A182K209   A0A2M4BE41   A0A2M4BDZ4   A0A2M4BDZ6   A0A1Q3FSB7   U5ESG9   D2A2U8   A0A139WIW2   A0A1D8I2M3   A0A1P8VK81   A0A182NFF1   V5G5Y4   Q176D3   A0A2M3ZFV5   A0A2M4A4G8   A0A182F160   W5JRT9   A0A182UM34   A0A182TWM4   A0A182XL08   A0A182L142   Q7Q455   A0A182HUE6   A0A2M3YZX5   A0A182GNU7   A0A182RX95   A0A182Y3K7   A0A182PF95   A0A182QJ39   A0A1L8E1Q7   A0A182W6U1   A0A182MG12   C8CCZ9   A0A023EVW9   A0A1B6M5T0   A0A1B0D3L9   A8D372   A0A1B6DMS5   B0WQL4   C8CGD1   A0A0L0C9U2   A0A0T6BDN0   I3UII1   A0A0K8TMP5   W8BEA7   U4UEP4   W8AI07   A0A034W4R7   W8B4D0   A0A034W337   J9JJR9   A0A0K8W1I3   J9WJ78   A0A0A1XDM0   A0A1B1PFM0   J9K2L1   T1PD62   A0A1A9WUV1  

EC Number

3.1.3.16

Pubmed

19121390    26354079    19004876    18492231    20193689    23622113    + More
22118469    22762304    20075255    20798317    21719571    21347285    24508170    30249741    24438588    20566863    28341416    28648823    18362917    19820115    17510324    20920257    23761445    20966253    12364791    14747013    17210077    26483478    25244985    24945155    26108605    26369729    24495485    23537049    25348373    22972362    25830018    25315136   

EMBL

BABH01038155    BABH01038156    ODYU01008350    SOQ51859.1    GU211889    ADA63844.1    + More
NWSH01008242    PCG62641.1    KQ459592    KPI96827.1    EU878265    ACH88521.1    EF051258    EU647215    ABM66814.2    ACD01424.1    KU977454    ARD05072.1    KQ460636    KPJ13381.1    MG787167    AYO46920.1    KY565574    ATU31386.1    KX013356    APD15513.1    KY565578    ATU31390.1    GAIX01012206    JAA80354.1    AGBW02008864    OWR52345.1    KX037427    ARN79552.1    JX025053    AFP67548.1    KQ760495    OAD60116.1    JR037900    JR037902    AEY58022.1    AEY58023.1    KQ414606    KOC69531.1    KZ288293    PBC29014.1    GL448433    EFN84652.1    KQ981799    KYN35667.1    KQ979074    KYN22879.1    GL888262    EGI63676.1    GBYB01015274    JAG85041.1    ADTU01003009    GL441177    EFN65057.1    GBYB01015278    JAG85045.1    KK107260    QOIP01000001    EZA54015.1    RLU27505.1    KQ982651    KYQ52855.1    KQ976434    KYM87221.1    LBMM01001097    KMQ96931.1    KQ978464    KYM93770.1    AJWK01012907    AJWK01012908    AJWK01012909    ATLV01020343    KE525299    KFB45146.1    DS235883    EEB20322.1    KY921835    ART29424.1    NNAY01000634    OXU27286.1    GGFJ01002122    MBW51263.1    GGFJ01002124    MBW51265.1    GGFJ01002123    MBW51264.1    GFDL01004722    JAV30323.1    GANO01003249    JAB56622.1    KQ971338    EFA02222.2    KYB27852.1    KU756283    AOT99586.1    KU578006    APZ77037.1    GALX01002996    JAB65470.1    CH477390    EAT41968.1    GGFM01006638    MBW27389.1    GGFK01002291    MBW35612.1    ADMH02000541    ETN66003.1    AAAB01008964    EAA12459.4    APCN01002455    GGFM01001045    MBW21796.1    JXUM01077203    KQ562993    KXJ74691.1    AXCN02000817    GFDF01001421    JAV12663.1    AXCM01003220    GQ389790    ACV32626.1    GAPW01000230    JAC13368.1    GEBQ01008697    JAT31280.1    AJVK01002975    EU131894    ABV44614.1    GEDC01010330    JAS26968.1    DS232041    EDS32889.1    GQ397450    ACV20871.1    JRES01000714    KNC29021.1    LJIG01001488    KRT85452.1    JQ743627    AFK64819.1    GDAI01001994    JAI15609.1    GAMC01018431    JAB88124.1    KB632144    ERL89081.1    GAMC01018430    JAB88125.1    GAKP01009822    JAC49130.1    GAMC01018429    JAB88126.1    GAKP01009823    JAC49129.1    ABLF02021486    GDHF01007322    JAI44992.1    JX462664    AFS17320.1    GBXI01005242    JAD09050.1    KU379749    ANT46147.1    ABLF02006957    ABLF02006958    KA646727    AFP61356.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000002358    + More
UP000053825    UP000242457    UP000005203    UP000008237    UP000078541    UP000078492    UP000007755    UP000005205    UP000000311    UP000053097    UP000279307    UP000075809    UP000078540    UP000036403    UP000078542    UP000092461    UP000030765    UP000009046    UP000215335    UP000075880    UP000075881    UP000007266    UP000075884    UP000008820    UP000069272    UP000000673    UP000075903    UP000075902    UP000076407    UP000075882    UP000007062    UP000075840    UP000069940    UP000249989    UP000075900    UP000076408    UP000075885    UP000075886    UP000075920    UP000075883    UP000092462    UP000002320    UP000037069    UP000030742    UP000007819    UP000095301    UP000091820   

PRIDE

H9J6P0   

Pfam

PF00982   Glyco_transf_20        + More
PF02358   Trehalose_PPase
PF00483   NTP_transferase
PF00132   Hexapep
PF00899   ThiF
PF00149   Metallophos

Interpro

IPR023214   HAD_sf        + More
IPR001830   Glyco_trans_20       
IPR036412   HAD-like_sf       
IPR003337   Trehalose_PPase       
IPR006379   HAD-SF_hydro_IIB       
IPR005835   NTP_transferase_dom       
IPR011992   EF-hand-dom_pair       
IPR002048   EF_hand_dom       
IPR029044   Nucleotide-diphossugar_trans       
IPR035985   Ubiquitin-activating_enz       
IPR000594   ThiF_NAD_FAD-bd       
IPR029752   D-isomer_DH_CS1       
IPR001451   Hexapep       
IPR004843   Calcineurin-like_PHP_ApaH       
IPR006186   Ser/Thr-sp_prot-phosphatase       
IPR029052   Metallo-depent_PP-like       

SUPFAM

SSF56784   SSF56784        + More
SSF69572   SSF69572       
SSF47473   SSF47473       
SSF53448   SSF53448       

Gene 3D

3.40.50.1000     3.90.550.10     3.60.21.10    

CDD

cd03788  GT1_TPS

ProteinModelPortal

H9J6P0   A0A2H1WFJ9   D2KHI8   A0A2A4ISC9   A0A194PU34   B5TD29   + More
A4GHG0   A0A2D0WL60   A0A0N1I975   A0A3G2SGU2   A0A2D3E2A0   A0A1J0M552   A0A2D3E238   S4NTI3   A0A212FF13   A0A1W6MPR2   J7G8S5   A0A310SSI4   V9IA83   K7IWD1   A0A0L7RFM2   A0A2A3EC11   A0A088A3B7   E2BI26   A0A151JTW4   A0A195EDF4   F4WQ53   A0A0C9RFD4   A0A158NX63   E2ANA9   A0A0C9QKI7   A0A026WD64   A0A151WYT2   A0A151I569   A0A0J7L2L4   A0A151I6N7   A0A1B0CHY7   A0A084W4K2   E0W3W6   A0A1Y0AWT0   A0A232F8Y6   A0A182J7Z1   A0A182K209   A0A2M4BE41   A0A2M4BDZ4   A0A2M4BDZ6   A0A1Q3FSB7   U5ESG9   D2A2U8   A0A139WIW2   A0A1D8I2M3   A0A1P8VK81   A0A182NFF1   V5G5Y4   Q176D3   A0A2M3ZFV5   A0A2M4A4G8   A0A182F160   W5JRT9   A0A182UM34   A0A182TWM4   A0A182XL08   A0A182L142   Q7Q455   A0A182HUE6   A0A2M3YZX5   A0A182GNU7   A0A182RX95   A0A182Y3K7   A0A182PF95   A0A182QJ39   A0A1L8E1Q7   A0A182W6U1   A0A182MG12   C8CCZ9   A0A023EVW9   A0A1B6M5T0   A0A1B0D3L9   A8D372   A0A1B6DMS5   B0WQL4   C8CGD1   A0A0L0C9U2   A0A0T6BDN0   I3UII1   A0A0K8TMP5   W8BEA7   U4UEP4   W8AI07   A0A034W4R7   W8B4D0   A0A034W337   J9JJR9   A0A0K8W1I3   J9WJ78   A0A0A1XDM0   A0A1B1PFM0   J9K2L1   T1PD62   A0A1A9WUV1  

PDB

5HUV     E-value=4.48131e-81,     Score=770

KEGG

101741435    K16055 trehalose 6-phosphate synthase/phosphatase [EC:2.4.1.15 3.1.3.12] | (RefSeq) alpha,alpha-treh

PATHWAY

00500    Starch and sucrose metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0003824   GO:0005992   GO:0003825   GO:0016779   GO:0008641   GO:0005509   GO:0004805   GO:0004721   GO:0016311   GO:0005829   GO:0005946   GO:0005737   GO:0070413   GO:0016740   GO:0016887   GO:0006520   GO:0006508   GO:0008237   GO:0016020   GO:0003707   GO:0051537  

Length:

733

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.0434400000000001

Exp number, first 60 AAs:

0.03888

Total prob of N-in:

0.00234

outside

1  -  733

 

 

Pi

20.262643

Theta

18.657715

Tajima's D

-1.707167

CLR

1.07757

CSRT

0.0357982100894955

Interpretation

Uncertain