Gene

KWMTBOMO07384  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010333

Annotation

putative_U2_snrnp_auxiliary_factor?_small_subunit_[Danaus_plexippus]

Location

Bomo_Chr12(+):11667200-11671193      View in EpiBrowser

Full name

Splicing factor U2af 38 kDa subunit      

Alternative Name

U2 auxiliary factor 38 kDa subunit
U2 snRNP auxiliary factor small subunit

Location in the cell

Nuclear   Reliability : 3.288

CDS

ATGGCAGAGTACTTGGCTGCTATATTTGGTACAGAAAAGGATAAAGTAAACTGTTCATTTTACTTCAAAATTGGAGCGTGCCGACACGGTGATCGCTGTTCACGCATTCATAACAAGCCAACCTTTTCTCAGACTGTATTACTACAAAACTTGTATGTAAATCCACAAAATTCTGCGAAATCAGCCGATGGCAGTCATTTGGTTGTTGCCAACGTGTCTGATGAAGAGATGCAGGAACACTATGACAACTTTTTTGAAGATGTATTTGTTGAATGCGAAGATAAATATGGTGAGATAGAAGAAATGAATGTTTGTGACAATCTTGGGGACCATTTAGTTGGAAATGTTTATATTAAATTTCGTCGAGAGGAAGATGCTGAGAAAGCAGTTAACGATTTAAATAACCGCTGGTTTGGAGGCCGGCCAGTCTATGCAGAACTCTCGCCGGTGACGGATTTTCGCGAAGCATGCTGTCGTCAGTATGAGATGGGAGAATGCACCCGAAGTGGATTTTGCAACTTCATGCATCTGAAACCTATTTCAAGAGAACTGAGAAGATACCTGTATTCCCGTCGCAAGAGCGGTCGTCGTTCCCGGTCCCGTTCCCGCGAGAGACGGCGCCGCTCCCGCTCCCGCGAGCGACGCCGCGAGCCGCCACGCACCTCGCGCTCCGGCCGCTACTGA

Protein

MAEYLAAIFGTEKDKVNCSFYFKIGACRHGDRCSRIHNKPTFSQTVLLQNLYVNPQNSAKSADGSHLVVANVSDEEMQEHYDNFFEDVFVECEDKYGEIEEMNVCDNLGDHLVGNVYIKFRREEDAEKAVNDLNNRWFGGRPVYAELSPVTDFREACCRQYEMGECTRSGFCNFMHLKPISRELRRYLYSRRKSGRRSRSRSRERRRRSRSRERRREPPRTSRSGRY

Description

Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity).

Subunit

Associates with a 65 kDa protein.

Similarity

Belongs to the splicing factor SR family.

Keywords

Complete proteome   Direct protein sequencing   Metal-binding   mRNA processing   mRNA splicing   Nucleus   Phosphoprotein   Reference proteome   Repeat   RNA-binding   Zinc   Zinc-finger  

Feature

chain  Splicing factor U2af 38 kDa subunit

Uniprot

H9JLD2   A0A2A4J1L1   A0A2H1V1M2   A0A212F3J8   S4PX57   A0A194R2K0   + More
E0VP11   A0A069DXH8   A0A194Q031   A0A224XJT3   A0A0P4VNF9   R4FL65   A0A161MZE3   A0A151WTU1   A0A0A9W7T9   A0A0J7L3E7   A0A195FVA7   E2AP33   A0A195EIS2   A0A151I7W5   F4W8I2   A0A195FBA0   A0A158NK83   E2AVE9   A0A151X703   K7IQM5   F4WY28   A0A0M8ZU24   A0A1B6DCY6   E2BQG9   A0A195DE69   A0A026X2T9   A0A0L7QWU7   A0A088AD43   A0A151IKH9   A0A195AZI5   A0A158NYK6   A0A154PEM2   A0A026X4D2   A0A1B6LVQ4   A0A1B6K0A1   A0A139WC73   E2C0D6   A0A1B0D0F1   A0A1L8DHB4   A0A1Y1LAK6   A0A067QEW8   A0A1S3DK33   A0A0C9RMN3   A0A3B0KAD3   A0A1A9XQH9   A0A1B0AUK9   A0A0A1XQ68   A0A1A9ZFK4   A0A1A9X5S1   A0A034WR22   A0A0K8TX53   A0A1B0FIG9   D0QWD9   A0A1S3CUW1   A0A2A3EK94   A0A0L0CFQ2   W8C9R7   A0A1A9UTD0   B4JBG7   A0A1L8EDB5   A0A1I8PUU7   B3MUJ6   A0A0M4E9B7   B4GJQ4   Q29NX1   B4KHH1   A0A1I8MV54   A0A182QJD1   B4P2C5   A0A1W4V460   M9PBM1   Q94535   B4LU48   B3N7N7   B4ICV2   B4Q622   A0A182RNC0   B4MWK0   A0A182J6B8   A0A336LPR3   A0A182KB40   C4WVT1   J9JM96   A0A0K8TS68   A0A182LG20   A0A182WRR6   Q7QD49   A0A084VEG6   W5JH55   A0A2H8TVE5   A0A182VYK6   A0A182FPQ0   A0A2M4BXT9   A0A2S2NSJ6  

Pubmed

19121390    22118469    23622113    26354079    20566863    26334808    + More
27129103    25401762    26823975    20798317    21719571    21347285    20075255    24508170    30249741    18362917    19820115    28004739    24845553    25830018    25348373    19859648    26108605    24495485    17994087    15632085    25315136    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    8816800    12537569    18327897    22936249    26369729    20966253    12364791    14747013    17210077    24438588    20920257    23761445   

EMBL

BABH01037115    BABH01037116    NWSH01003954    PCG65626.1    ODYU01000269    SOQ34743.1    + More
AGBW02010564    OWR48292.1    GAIX01005618    JAA86942.1    KQ460845    KPJ12018.1    DS235354    EEB15117.1    GBGD01002830    JAC86059.1    KQ459592    KPI96775.1    GFTR01003679    JAW12747.1    GDKW01002121    JAI54474.1    ACPB03017557    GAHY01002219    JAA75291.1    GEMB01003454    JAR99761.1    KQ982748    KYQ51329.1    GBHO01039102    GBRD01004907    GDHC01018655    JAG04502.1    JAG60914.1    JAP99973.1    LBMM01000835    KMQ97397.1    KQ981276    KYN43799.1    GL441990    GL441439    EFN64036.1    EFN64865.1    KQ978881    KYN27797.1    KQ978406    KYM94170.1    GL887908    EGI69473.1    KQ981693    KYN37656.1    ADTU01018740    GL443090    EFN62583.1    KQ982472    KYQ56109.1    GL888434    EGI60953.1    KQ435878    KOX69996.1    GEDC01013759    JAS23539.1    GL449769    EFN82027.1    KQ980953    KYN11181.1    KK107021    QOIP01000011    EZA62336.1    RLU16531.1    KQ414706    KOC63070.1    KQ977202    KYN04982.1    KQ976701    KYM77369.1    ADTU01004017    KQ434889    KZC10302.1    KK107013    QOIP01000003    EZA62891.1    RLU24522.1    GEBQ01023604    GEBQ01012221    JAT16373.1    JAT27756.1    GECU01003133    JAT04574.1    KQ971371    KYB25506.1    GL451770    EFN78595.1    AJVK01021358    GFDF01008236    JAV05848.1    GEZM01064890    GEZM01064889    JAV68616.1    KK853809    KDQ71588.1    GBYB01014682    JAG84449.1    OUUW01000006    SPP81991.1    JXJN01003674    GBXI01001604    JAD12688.1    GAKP01002175    GAKP01002174    JAC56777.1    GDHF01033659    GDHF01011753    GDHF01008928    JAI18655.1    JAI40561.1    JAI43386.1    CCAG010003108    FJ821025    ACN94635.1    KZ288220    PBC32147.1    JRES01000536    KNC30319.1    GAMC01001924    JAC04632.1    CH916368    EDW03990.1    GFDG01002230    JAV16569.1    CH902624    EDV33525.1    CP012523    ALC38764.1    CH479184    EDW36870.1    CH379058    EAL34522.3    CH933807    EDW11235.1    AXCN02001589    CM000157    EDW87121.1    AE014134    AGB92351.1    U67066    AY058537    CH940649    EDW64035.1    CH954177    EDV57213.1    CH480829    EDW45378.1    CM000361    CM002910    EDX03206.1    KMY87288.1    CH963857    EDW76141.2    UFQT01000037    UFQT01003367    SSX18377.1    SSX34919.1    AK341658    BAH72001.1    ABLF02031184    GDAI01000828    JAI16775.1    AAAB01008859    EAA08115.3    ATLV01012277    KE524778    KFB36360.1    ADMH02001205    ETN63697.1    GFXV01006440    MBW18245.1    GGFJ01008729    MBW57870.1    GGMR01007117    MBY19736.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053240    UP000009046    UP000053268    + More
UP000015103    UP000075809    UP000036403    UP000078541    UP000000311    UP000078492    UP000078542    UP000007755    UP000005205    UP000002358    UP000053105    UP000008237    UP000053097    UP000279307    UP000053825    UP000005203    UP000078540    UP000076502    UP000007266    UP000092462    UP000027135    UP000079169    UP000268350    UP000092443    UP000092460    UP000092445    UP000091820    UP000092444    UP000242457    UP000037069    UP000078200    UP000001070    UP000095300    UP000007801    UP000092553    UP000008744    UP000001819    UP000009192    UP000095301    UP000075886    UP000002282    UP000192221    UP000000803    UP000008792    UP000008711    UP000001292    UP000000304    UP000075900    UP000007798    UP000075880    UP000075881    UP000007819    UP000075882    UP000076407    UP000007062    UP000030765    UP000000673    UP000075920    UP000069272   

PRIDE

H9JLD2    M9PBM1    Q94535   

Pfam

PF00642   zf-CCCH        + More
PF00076   RRM_1

Interpro

IPR012677   Nucleotide-bd_a/b_plait_sf        + More
IPR035979   RBD_domain_sf       
IPR000504   RRM_dom       
IPR000571   Znf_CCCH       
IPR003954   RRM_dom_euk       
IPR009145   U2AF_small       

SUPFAM

SSF54928   SSF54928       

Gene 3D

3.30.70.330    

ProteinModelPortal

H9JLD2   A0A2A4J1L1   A0A2H1V1M2   A0A212F3J8   S4PX57   A0A194R2K0   + More
E0VP11   A0A069DXH8   A0A194Q031   A0A224XJT3   A0A0P4VNF9   R4FL65   A0A161MZE3   A0A151WTU1   A0A0A9W7T9   A0A0J7L3E7   A0A195FVA7   E2AP33   A0A195EIS2   A0A151I7W5   F4W8I2   A0A195FBA0   A0A158NK83   E2AVE9   A0A151X703   K7IQM5   F4WY28   A0A0M8ZU24   A0A1B6DCY6   E2BQG9   A0A195DE69   A0A026X2T9   A0A0L7QWU7   A0A088AD43   A0A151IKH9   A0A195AZI5   A0A158NYK6   A0A154PEM2   A0A026X4D2   A0A1B6LVQ4   A0A1B6K0A1   A0A139WC73   E2C0D6   A0A1B0D0F1   A0A1L8DHB4   A0A1Y1LAK6   A0A067QEW8   A0A1S3DK33   A0A0C9RMN3   A0A3B0KAD3   A0A1A9XQH9   A0A1B0AUK9   A0A0A1XQ68   A0A1A9ZFK4   A0A1A9X5S1   A0A034WR22   A0A0K8TX53   A0A1B0FIG9   D0QWD9   A0A1S3CUW1   A0A2A3EK94   A0A0L0CFQ2   W8C9R7   A0A1A9UTD0   B4JBG7   A0A1L8EDB5   A0A1I8PUU7   B3MUJ6   A0A0M4E9B7   B4GJQ4   Q29NX1   B4KHH1   A0A1I8MV54   A0A182QJD1   B4P2C5   A0A1W4V460   M9PBM1   Q94535   B4LU48   B3N7N7   B4ICV2   B4Q622   A0A182RNC0   B4MWK0   A0A182J6B8   A0A336LPR3   A0A182KB40   C4WVT1   J9JM96   A0A0K8TS68   A0A182LG20   A0A182WRR6   Q7QD49   A0A084VEG6   W5JH55   A0A2H8TVE5   A0A182VYK6   A0A182FPQ0   A0A2M4BXT9   A0A2S2NSJ6  

PDB

4YH8     E-value=1.17811e-59,     Score=579

KEGG

101742886    K12836 splicing factor U2AF 35 kDa subunit | (RefSeq) splicing factor U2af 38 kDa subunit

PATHWAY

03040    Spliceosome - Bombyx mori (domestic silkworm)

GO

GO:0046872   GO:0089701   GO:0003723   GO:0000398   GO:0005681   GO:0030628   GO:0008187   GO:0000381   GO:0016021   GO:0003729   GO:0005634   GO:0071011   GO:0008380   GO:0000166   GO:0003676   GO:0005215   GO:0043022   GO:0005488   GO:0003707   GO:0051537  

PANTHER

PTHR12620  

Subcellular location

Nucleus  

Length:

227

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0

Exp number, first 60 AAs:

0

Total prob of N-in:

0.02545

outside

1  -  227

 

 

Pi

19.968299

Theta

17.15251

Tajima's D

0.569846

CLR

0.374181

CSRT

0.539073046347683

Interpretation

Uncertain