Gene

KWMTBOMO07375

Pre Gene Modal

BGIBMGA005180

Annotation

PREDICTED:_DNA_repair_endonuclease_XPF_[Amyelois_transitella]

Location

Bomo_Chr12(+):11522600-11535077      View in EpiBrowser

Full name

DNA repair endonuclease XPF      

Alternative Name

Protein meiotic 9

Location in the cell

Nuclear   Reliability : 3.474

CDS

ATGTTGTCATTCGAAAAGCAAATCTTCATTGATGTGTTTGAAAAAGATGCTCTTGTAATAATGGCAAAAGGCCATAATTACAACAACATTGTGGCTAATTTGTTGTGGGTGCACAAGGATCCTGGTAATCTAGTTTTAGTTATAAACAGTAATGATAATGAAGAAAAATATTTTACTGAAAAAAATCAATTGACACCAGTACCCACACTTGGCAATGAAAGAGAGCGGTCGTATTTAGAGGGTGGAATTCATTTTGTATCAACTCGTATTTTGGTTGTGGATTTATTAAAAAACAGAGTGCCAATATCCCATATCACAGGCATTGTTGTTCTAAGAGCACACACAGTCTTAGAATCATGTCAGGAAGCATTTGCATTGAGGTTGTACAGGCAGAAAAATAAGACTGGATTTATTAAAGCATTTTCTAATTCACCTATCTCTTTCACGTTTGGATACCATCAAGTTGAGAAAGTTATGAGGGCGCTTTTTGTGACAGAACTATTTCTGTGGCCAAGGTTTCATGGCAACATTATTAGAAATTTAAAGAGTAGACAAGCTCAAGCTGAAGAACTTCACATTCCATTAACTACTAACATGAGCTACATTCAGACGTGTCTTCTTGACATTATGAACTACACTGTCAAACAATTGAAGAGCATTAACAGGTCTTTAGATATGAAAGAAATCACAACCGAGAATTGTATAACAAAGAAATTTCATAAGATCCTGCAATCGCAGCTGGATTGTGTGTGGCATCAACTTAGTACAAGAACAAAGGAATACATACAAGACCTAAAAATTCTCAGGAGCATGATTATTAACCTAATACACGATGACGCGGTGTCGTTATACGCGTTAGTCAGCAAGTACCGAACTCCTGAATACGCACAAATAAATTCTGGTTGGATCCTGCTCGAGTCTGCGGAGCAGCTGTTTAAATACGCCAAAGCACGTGTATTTAATAAAAAGAACGAATTCGATCCGGAGCCTTCACCGAAATGGAAGTACTTAAGCGATTTGTTATCCCAAGAAATACCAGACGAAGTAAACAAAAAGAAAGACAGTAACTTGAGCAACACTAAAATATTAATTCTCTGCCAAGACAATCGGACCTGTAGCCAGCTGAACCACTTCCTCACCATGGGGGCAAATAGATACCTGCTGTACACGGCTTTCAAACGTGAGATCCCCATAAATGCAGTAGCGACAAAATACGAAGACATAAAAAACACAGTTCCCGTAGAAACTAAAGATAAGACAGACAAAAAGTCGGATACAAAAGAAGGAAAATCTACCGATGAAGGCACACGTTTGGATGACTCGAAATATGAAGAATTGAACACAGAAGAATCGAGAACTAATTATCTGTTGACGCTAACACAAAGTTCAGCGCACTGCAGCAAAGATAATGCAACAGTTAATGAAAGTTTATTCGAACCCATTTCCCAGCTGGATAATTTAGATTTTACGAAAATCGAAGTAGAAACGCCCGTAATCTGCATCCAAACGTTCAAAGAAAACGGTAACAATCTCTCCTTGGAATACACTCTGGAAGCTTTGAGACCGGAATATGTTATACTGTATCACAGCGACGTGGCAGCTGTGCGCCAGCTGGAGATGTACGAGTGCAGAAAGAAACCGGAGGAGCCGATCTGCAAAGTGTACTTCCTGATACACGATCAAACAGTTGAGGAGCAAGCCTATCTGGCGGCATTGAAGAGAGAAAAACAAGCATTTGAATTGTTGATTCAGGCCAAAAGTGTCATGGTAGTTCCTTCATATCAAGACGGAAAAACAGATGAATACTTCCAATTAACAAACGAGGAAGAAGTGCAACCCACCGATTCAAGGAAAGCAGGTCAAAATCAAAGTAAAGAGAAACCGCTAGTGATAGTGGACATGAGAGAGTTTCGATCAGACTTACCGTCGCTGTTGCACAAGAGAGGCATTAATATCGAACCAGTTACGATAGCGATAGGTGATTACATACTGACCCCTGATATTTGCGTAGAAAGGAAATCTATATCCGATTTGATTGGATCGTTGAACTCTGGTCGCTTGTACACACAATGCACACAAATGTGCCGCAACTACAGTCGACCTATCCTGCTTATTGAATTTGATCAAAATAAACCTTTTAATCTTCAGGGTCATTTCGTGGTATCAACAGATATATCTGGAGCGGATATACAACAAAAACTACAACTTCTGACAATACATTTCCCTAGGCTGAAATTGGTATGGTCGCCAAGTCCGTATGCTACTGCTGAACTTTTCTATGAATTAAAGCAAGGCAGAAATAATCCCAATATTGCAGAAGCTATCGCTCTCAGTGGTGAAAATACCGCAGATGATATGAACTATGAGAGATACAATATATTGGTTCATGATTTCGTACAAAAACTACCTGGTGTTACATCAAAAAACATTAACAGAATTATGAACAAAGGTATCTCACTGGACCACTTGATAACTCTTACCAAAGAGGAATTATCTGATGTCGTAGAAAACAAAAATGAAGCCGAAACACTGTATTCAATACTTCACGTCAAAGCTCGTCCCATGGATGCCAAAGAAGAGAAATTCGGAAAGAAAAAGTTCACTGGAAAACTATATCGTAGTAAAAAATAA

Protein

MLSFEKQIFIDVFEKDALVIMAKGHNYNNIVANLLWVHKDPGNLVLVINSNDNEEKYFTEKNQLTPVPTLGNERERSYLEGGIHFVSTRILVVDLLKNRVPISHITGIVVLRAHTVLESCQEAFALRLYRQKNKTGFIKAFSNSPISFTFGYHQVEKVMRALFVTELFLWPRFHGNIIRNLKSRQAQAEELHIPLTTNMSYIQTCLLDIMNYTVKQLKSINRSLDMKEITTENCITKKFHKILQSQLDCVWHQLSTRTKEYIQDLKILRSMIINLIHDDAVSLYALVSKYRTPEYAQINSGWILLESAEQLFKYAKARVFNKKNEFDPEPSPKWKYLSDLLSQEIPDEVNKKKDSNLSNTKILILCQDNRTCSQLNHFLTMGANRYLLYTAFKREIPINAVATKYEDIKNTVPVETKDKTDKKSDTKEGKSTDEGTRLDDSKYEELNTEESRTNYLLTLTQSSAHCSKDNATVNESLFEPISQLDNLDFTKIEVETPVICIQTFKENGNNLSLEYTLEALRPEYVILYHSDVAAVRQLEMYECRKKPEEPICKVYFLIHDQTVEEQAYLAALKREKQAFELLIQAKSVMVVPSYQDGKTDEYFQLTNEEEVQPTDSRKAGQNQSKEKPLVIVDMREFRSDLPSLLHKRGINIEPVTIAIGDYILTPDICVERKSISDLIGSLNSGRLYTQCTQMCRNYSRPILLIEFDQNKPFNLQGHFVVSTDISGADIQQKLQLLTIHFPRLKLVWSPSPYATAELFYELKQGRNNPNIAEAIALSGENTADDMNYERYNILVHDFVQKLPGVTSKNINRIMNKGISLDHLITLTKEELSDVVENKNEAETLYSILHVKARPMDAKEEKFGKKKFTGKLYRSKK

Subunit

Heterodimer (By similarity). Interacts with hdm.

Similarity

Belongs to the XPF family.

Keywords

Complete proteome   DNA damage   DNA repair   DNA-binding   Endonuclease   Hydrolase   Meiosis   Nuclease   Nucleus   Reference proteome  

Feature

chain  DNA repair endonuclease XPF

Uniprot

A0A3S2NRS2   A0A212F3J3   A0A194PTM5   A0A194R2V2   A0A2H1VNE8   A0A1E1WJ72   + More
A0A2A4IUY9   A0A1I8P6G3   W8BG68   A0A1I8M666   Q29FQ4   A0A1W4V1G6   A0A1A9ZVD3   A0A0A1WM55   B4GTY4   A0A1Y1JT47   A0A034WDQ6   A0A0K8UYR4   A0A0M3QZ63   A0A1A9XAJ4   A0A1B0ATA9   T2FFI3   Q24087   A0A1A9UPJ2   A0A1A9WG73   A0A3B0K781   B4L6Q4   B4Q069   B4NP89   B3NU19   A0A336M4G7   B3MSI5   B4JMQ3   A0A0L0CGH6   B4M7P7   A0A336MFC1   Q17J54   A0A1W4WJ37   A0A1J1IGF4   D6WJT6   A0A0J7KEA4   A0A232F607   U4TZA3   N6TEU9   A0A1B6EY17   A0A026WM20   E2B2N4   A0A3L8E4Q4   E2A3B3   A0A0N0BE83   A0A2Z5U214   A0A067R0V8   A0A2A3EF28   A0A1B0FGJ6   A0A154PG49   A0A1B6E0K5   A0A2S2QUC3   A0A2H8TG83   A0A224XJV8   A0A088AAW9   A0A0A9ZJ13   J9JL14   A0A158NY48   T1HKQ6   A0A1Y1JT32   A0A151IE27   V4C7S3   A0A1S3J1P2   A0A1S3IMB0   K1P9V1   A0A0P4W933   A0A210R1E3   A0A2C9KG40   A0A1Z5LEM3   A0A2C9KG37   A0A2T7NQ56   H3ABZ1   R7TEW3   A0A131XJX8   L7M9M1   A0A224YUW8   A0A131YWV5   A0A2Y9DFR3   L7MLT1   A0A182G9Y0   F6R8S0   A0A0K2T0T9   A0A3P8WV94   A0A3Q0RCE3   A0A3B5AHN8   A0A3Q3BI53   A0A0L8HK36   A0A3B4C2C1   A0A3Q1I007   U3J3D1   A0A3Q2ZFV8   A0A3Q3GJQ8   A0A3Q3VSZ3   A0A2K6ES99   A0A2I4D8D4  

EC Number

3.1.-.-

Pubmed

22118469    26354079    24495485    25315136    15632085    17994087    + More
25830018    28004739    25348373    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    8647398    12537569    18957705    17550304    26108605    17510324    18362917    19820115    28648823    23537049    24508170    20798317    30249741    26760975    24845553    25401762    21347285    23254933    22992520    28812685    15562597    28528879    9215903    28049606    25576852    28797301    26830274    26483478    19892987    24487278    23749191   

EMBL

RSAL01000116    RVE46864.1    AGBW02010564    OWR48283.1    KQ459592    KPI96766.1    + More
KQ460845    KPJ12027.1    ODYU01003476    SOQ42317.1    GDQN01004143    JAT86911.1    NWSH01006888    PCG63198.1    GAMC01006260    JAC00296.1    CH379065    EAL31525.2    GBXI01014809    JAC99482.1    CH479190    EDW26004.1    GEZM01101618    JAV52442.1    GAKP01006133    JAC52819.1    GDHF01020616    JAI31698.1    CP012528    ALC48873.1    JXJN01003231    BT150257    AE014298    AGV77159.1    AHN59330.1    U27181    BT001319    OUUW01000018    SPP89163.1    CH933812    EDW06050.1    CM000162    EDX01221.1    CH964291    EDW86329.1    CH954180    EDV45795.1    UFQT01000387    SSX23823.1    CH902622    EDV34740.2    CH916371    EDV91996.1    JRES01000430    KNC31345.1    CH940653    EDW62814.1    UFQT01001121    SSX29005.1    CH477234    EAT46753.1    CVRI01000048    CRK98620.1    KQ971343    EFA04567.1    LBMM01008502    KMQ88823.1    NNAY01000882    OXU26075.1    KB631899    ERL86939.1    APGK01040820    KB740984    ENN76293.1    GECZ01027038    GECZ01020036    JAS42731.1    JAS49733.1    KK107168    EZA56134.1    GL445190    EFN90056.1    QOIP01000001    RLU27522.1    GL436354    EFN72085.1    KQ435844    KOX71272.1    FX985834    BBA93721.1    KK852822    KDR15512.1    KZ288267    PBC30084.1    CCAG010010420    KQ434886    KZC10170.1    GEDC01005832    JAS31466.1    GGMS01011529    MBY80732.1    GFXV01001245    MBW13050.1    GFTR01008115    JAW08311.1    GBHO01000389    GBRD01010326    JAG43215.1    JAG55498.1    ABLF02040901    ADTU01003143    ADTU01003144    ACPB03014634    GEZM01101617    JAV52444.1    KQ977914    KYM98817.1    KB201304    ESO97764.1    JH815775    EKC18198.1    GDRN01071374    GDRN01071373    JAI63699.1    NEDP02000888    OWF54777.1    GFJQ02001111    JAW05859.1    PZQS01000010    PVD23305.1    AFYH01147897    AFYH01147898    AFYH01147899    AMQN01003141    KB311062    ELT90017.1    GEFH01002740    JAP65841.1    GACK01005230    JAA59804.1    GFPF01007255    MAA18401.1    GEDV01006156    JAP82401.1    GACK01000069    JAA64965.1    JXUM01049950    JXUM01049951    JXUM01049952    JXUM01049953    JXUM01049954    JXUM01049955    JXUM01049956    JXUM01049957    KQ561628    KXJ77953.1    HACA01002277    CDW19638.1    KQ417942    KOF89596.1    ADON01130592    ADON01130593    ADON01130594   

Proteomes

UP000283053    UP000007151    UP000053268    UP000053240    UP000218220    UP000095300    + More
UP000095301    UP000001819    UP000192221    UP000092445    UP000008744    UP000092553    UP000092443    UP000092460    UP000000803    UP000078200    UP000091820    UP000268350    UP000009192    UP000002282    UP000007798    UP000008711    UP000007801    UP000001070    UP000037069    UP000008792    UP000008820    UP000192223    UP000183832    UP000007266    UP000036403    UP000215335    UP000030742    UP000019118    UP000053097    UP000008237    UP000279307    UP000000311    UP000053105    UP000027135    UP000242457    UP000092444    UP000076502    UP000005203    UP000007819    UP000005205    UP000015103    UP000078542    UP000030746    UP000085678    UP000005408    UP000242188    UP000076420    UP000245119    UP000008672    UP000014760    UP000248480    UP000069940    UP000249989    UP000002281    UP000265120    UP000261340    UP000261400    UP000264800    UP000053454    UP000261440    UP000265040    UP000016666    UP000264820    UP000261660    UP000261620    UP000233160    UP000192220   

PRIDE

T2FFI3    Q24087   

Pfam

PF02732   ERCC4        + More
PF13181   TPR_8
PF17065   UPF0669
PF06462   Hyd_WA

Interpro

IPR006166   ERCC4_domain        + More
IPR010994   RuvA_2-like       
IPR011335   Restrct_endonuc-II-like       
IPR006167   XPF       
IPR013026   TPR-contain_dom       
IPR011990   TPR-like_helical_dom_sf       
IPR019734   TPR_repeat       
IPR031420   UPF0669       
IPR006624   Beta-propeller_rpt_TECPR       
IPR006614   Peroxin/Ferlin       
IPR000626   Ubiquitin_dom       

SUPFAM

SSF52980   SSF52980        + More
SSF47781   SSF47781       
SSF48452   SSF48452       

Gene 3D

1.25.40.10    

ProteinModelPortal

A0A3S2NRS2   A0A212F3J3   A0A194PTM5   A0A194R2V2   A0A2H1VNE8   A0A1E1WJ72   + More
A0A2A4IUY9   A0A1I8P6G3   W8BG68   A0A1I8M666   Q29FQ4   A0A1W4V1G6   A0A1A9ZVD3   A0A0A1WM55   B4GTY4   A0A1Y1JT47   A0A034WDQ6   A0A0K8UYR4   A0A0M3QZ63   A0A1A9XAJ4   A0A1B0ATA9   T2FFI3   Q24087   A0A1A9UPJ2   A0A1A9WG73   A0A3B0K781   B4L6Q4   B4Q069   B4NP89   B3NU19   A0A336M4G7   B3MSI5   B4JMQ3   A0A0L0CGH6   B4M7P7   A0A336MFC1   Q17J54   A0A1W4WJ37   A0A1J1IGF4   D6WJT6   A0A0J7KEA4   A0A232F607   U4TZA3   N6TEU9   A0A1B6EY17   A0A026WM20   E2B2N4   A0A3L8E4Q4   E2A3B3   A0A0N0BE83   A0A2Z5U214   A0A067R0V8   A0A2A3EF28   A0A1B0FGJ6   A0A154PG49   A0A1B6E0K5   A0A2S2QUC3   A0A2H8TG83   A0A224XJV8   A0A088AAW9   A0A0A9ZJ13   J9JL14   A0A158NY48   T1HKQ6   A0A1Y1JT32   A0A151IE27   V4C7S3   A0A1S3J1P2   A0A1S3IMB0   K1P9V1   A0A0P4W933   A0A210R1E3   A0A2C9KG40   A0A1Z5LEM3   A0A2C9KG37   A0A2T7NQ56   H3ABZ1   R7TEW3   A0A131XJX8   L7M9M1   A0A224YUW8   A0A131YWV5   A0A2Y9DFR3   L7MLT1   A0A182G9Y0   F6R8S0   A0A0K2T0T9   A0A3P8WV94   A0A3Q0RCE3   A0A3B5AHN8   A0A3Q3BI53   A0A0L8HK36   A0A3B4C2C1   A0A3Q1I007   U3J3D1   A0A3Q2ZFV8   A0A3Q3GJQ8   A0A3Q3VSZ3   A0A2K6ES99   A0A2I4D8D4  

PDB

2BGW     E-value=2.2671e-12,     Score=178

KEGG

101742198    K10848 DNA excision repair protein ERCC-4 [EC:3.1.-.-] | (RefSeq) DNA repair endonuclease XPF-like

PATHWAY

03420    Nucleotide excision repair - Bombyx mori (domestic silkworm)
03460    Fanconi anemia pathway - Bombyx mori (domestic silkworm)

GO

GO:0006281   GO:0004520   GO:0003697   GO:0004519   GO:0003677   GO:0004518   GO:0032991   GO:0006298   GO:0000712   GO:0006302   GO:0046982   GO:0016321   GO:0030716   GO:0006289   GO:0006974   GO:0045132   GO:0006310   GO:0007131   GO:0005634   GO:0007143   GO:0000724   GO:0000014   GO:0006296   GO:0003684   GO:1901255   GO:0000110   GO:0016021   GO:0006303   GO:0000784   GO:1905768   GO:0047485   GO:0005669   GO:0061819   GO:0034644   GO:0006295   GO:0070522   GO:0042802   GO:0001094   GO:0008022   GO:1990599   GO:0009650   GO:1905765   GO:0010506   GO:1904357   GO:0006259   GO:0043022   GO:0005488   GO:0003707   GO:0051537  

Subcellular location

Nucleus  

Length:

876

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02191

Exp number, first 60 AAs:

0.00054

Total prob of N-in:

0.00112

outside

1  -  876

 

 

Pi

23.319878

Theta

21.220978

Tajima's D

0.432062

CLR

0.508044

CSRT

0.498325083745813

Interpretation

Uncertain