Gene

KWMTBOMO07371

Pre Gene Modal

BGIBMGA010354

Annotation

hypothetical_protein_KGM_15726_[Danaus_plexippus]

Location

Bomo_Chr12(+):11465320-11486074      View in EpiBrowser

Full name

Protein turtle      

Location in the cell

Extracellular   Reliability : 1.41 PlasmaMembrane   Reliability : 1.028

CDS

ATGGGCTGGCGCGCCGTGCAACCGCCGCACATCGCCGCCGGCTTGCTCCTCCTGCTGCTTGTCAATCTACCAGTGACCTGCCATCAAGACCACCAAGATGCCGTGCACATCACGGCTATCCTCGGTGAAAGTGTCGTGTTCAACTGTCAGGTGGATTTTCCCGAAGATATCCCGGTGCCGTACGTGTTGCAGTGGGAGAAGAAGGTAGGCGAAACGGGACAGGACATCCCGATCTACATCTGGTACGAGAGCTATCCGACGCATAGCGGGGAGGGCTACGAAGGCAGAGTGTCCCGCGTCGCAACCGACTCACCGTACGGCGCCGCAAGCCTCAACCTCACCAACATTCGAGAATCGGATCAGGGTTGGTACGAGTGTAAAGTGGTTTTTCTCAACCGATCACCAAACCAGCATAAGAATGGTACATGGTTCCACTTGGACGTGCACGCGCCACCTCGCTTCTCCATCACACCGGAAGACATTATATACGTTAATTTAGGCGATGCGATTATACTTAACTGCCAAGCAGAGGGAACACCAACTCCTGAAATACTATGGTATAAAGATGCAAACCCCGTCGAACCATCCGGTACTGTAGGTATATTTAACGATGGAACCGAACTGCGAATTAGTAACATTCGACACGAAGACATCGGTGATTACACGTGTATAGCGCGGAATGGAGAAGGTCAGGTATCTCACACGGCACGTGTCATTATCGCTGGTGGAGCTGTCATAACCATGCCACCGACAAATCAAACTAAACTGGAAGGAGAGAAAGTCCAGTTTTCGTGTGAAGCGAAGGCTCTGCCCGGAAATGTGACTGTGAAGTGGTTTCGTGAGGGTGCACCTGTGGCCGAGGTGGCGGCTTTGGAAACAAGAGTCACCATCCGCAGAGACGGAGCTCTTGTCATTAACCCTGTAGCTGCTGACGACTCCGGACAGTATTTGTGTGAAGTTTCTAATGGCATCGGAGACCCACAAAGCGCATCGGCCTATCTTAATGTTGAATATCCGGCGAAAGTAACCTTTACACCCACAGTTCAGTATTTGCCCTTCCGTTTGGCCGGAGTGGTTCAATGTTACATAAAAGCCAATCCACCTCTGCAGTACGTTACTTGGACAAAAGACAAGAGATTATTGGAGCCTTATCAAACGAAGGACATTGTTATAATGAACAACGGATCATTGTTATTTACCAGAGTTAACCAAAATCACCAGGGCCGGTACACTTGCACTCCTTATAACGCTCAAGGAACCCAAGGTTCTTCTGGTCCAATGGAAGTTCTAGTTCGGAAACCACCGGTGTTCACAGTGGAACCCGAACCATTATATCAGAGGAAGGTCGGTGAATCTGTAGAGATGCACTGCGAAGCACAAGAGTCTGAAGGCACACAGCGACCGAGCGTGACGTGGCGGCGGCGTGACGGTCTACCGCTTCAGAAGAACAGAGTCCGAGCTGTGGGCGGAAACATCACCATCGATACACTGCGCCGACAAGACTTTGGTATCTACCAATGTGTCGCGTCCAATGAGGTGGCAACAATCGTAGCGGACACGCAATTAGTGATAGAAGGCACGCAACCCCATGCTCCGTACAATGTGTCTGGAACAGCAACTGAGTTCCAAGTTACTTTGCGGTGGCAACCAGGATACGCCGGAGGTCCTGACTACAAACAGGACTATACGATATGGTACAGGGAAGCTGGATTTTCTGAGTGGACCAAAGTTCCCGTGACGCCCCCTGGTGCTACATCTGTAACAATTAACCGTCTACAACCTGGGACAACATACGAGTTTCAAGTAAATAGCAAGAATACTATAGGCGAAGGAATGATGAGTAAAGCAATTACAATAAGAACGCTCGATGTAGGTGCCAAGCCAAAGGTACCCACGACCGCCGCTGGTCCTATCGACGAAAAGATATTTCAAAACGCACCTGAAGGCTCCGGCCCGAAACCAGGTCCCCCACGGAATCTGACAGTGACAGAGGTTCATAATGGATTCTTAATAACTTGGCAAGGACCTTTAGAACGTGCGCAGCTTGTTCAGTACTACACCATCAAGTACCGCACTGACGCGCAGTGGAAGACCCTCAACAGGGGCCAGATACGACCTGAAGAGACCAGTTATTTAGTTAAGAACTTAGTCGGCGGGCGTACTTATTATTTTCGAGTACTCGCGAACTCGGCGACCAGCTACGAGAGTTCGGACGAAGTGAGGTTCCCGGTGCCGGCACGCGTGAAGCACAAAGCGATCACGGCTGGTGTCGTGGGTGGGATTCTGTTCTTCATCGTCGCCATCATACTGTCCGTGTGTGCCGTCAAGATATGTAACAAGCGTAAACGGCGTAAGCAGGAGAAAGAAATTATACGATTACAGCATACAACATGGTAG

Protein

MGWRAVQPPHIAAGLLLLLLVNLPVTCHQDHQDAVHITAILGESVVFNCQVDFPEDIPVPYVLQWEKKVGETGQDIPIYIWYESYPTHSGEGYEGRVSRVATDSPYGAASLNLTNIRESDQGWYECKVVFLNRSPNQHKNGTWFHLDVHAPPRFSITPEDIIYVNLGDAIILNCQAEGTPTPEILWYKDANPVEPSGTVGIFNDGTELRISNIRHEDIGDYTCIARNGEGQVSHTARVIIAGGAVITMPPTNQTKLEGEKVQFSCEAKALPGNVTVKWFREGAPVAEVAALETRVTIRRDGALVINPVAADDSGQYLCEVSNGIGDPQSASAYLNVEYPAKVTFTPTVQYLPFRLAGVVQCYIKANPPLQYVTWTKDKRLLEPYQTKDIVIMNNGSLLFTRVNQNHQGRYTCTPYNAQGTQGSSGPMEVLVRKPPVFTVEPEPLYQRKVGESVEMHCEAQESEGTQRPSVTWRRRDGLPLQKNRVRAVGGNITIDTLRRQDFGIYQCVASNEVATIVADTQLVIEGTQPHAPYNVSGTATEFQVTLRWQPGYAGGPDYKQDYTIWYREAGFSEWTKVPVTPPGATSVTINRLQPGTTYEFQVNSKNTIGEGMMSKAITIRTLDVGAKPKVPTTAAGPIDEKIFQNAPEGSGPKPGPPRNLTVTEVHNGFLITWQGPLERAQLVQYYTIKYRTDAQWKTLNRGQIRPEETSYLVKNLVGGRTYYFRVLANSATSYESSDEVRFPVPARVKHKAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQEKEIIRLQHTTW

Description

Essential protein that plays a role in the establishment of coordinated motor control (PubMed:11312296). In the developing eye, involved in axonal targeting of the R7 photoreceptor (PubMed:24174674).

Subunit

Interacts with bdl.

Similarity

Belongs to the AB hydrolase superfamily. Lipase family.
Belongs to the immunoglobulin superfamily. Turtle family.

Keywords

Alternative splicing   Complete proteome   Disulfide bond   Immunoglobulin domain   Membrane   Neurogenesis   Reference proteome   Repeat   Transmembrane   Transmembrane helix  

Feature

chain  Protein turtle
splice variant  In isoform 3.

Uniprot

A0A1U9XRB3   A0A2A4J3J1   A0A212F3G4   A0A3S2NX96   A0A2A4J2M0   A0A194PUV0   + More
A0A194R837   A0A2H1V9G2   A0A2A4J4G3   Q7Q3K8   A0A1S4J7Q9   A0A1S4GWQ1   A0A1S4FDQ5   A0A084VP30   Q0IF39   A0A182PJ73   A0A182JK20   A0A182F4L4   A0A182HV77   A0A1Y1MQA9   A0A182NE36   A0A1Y1MQ97   A0A1J1ID06   A0A182UV49   A0A182RBL8   A0A1Y1MTP8   A0A1Y1MTN2   A0A182WT84   A0A182YGU3   A0A154PTC6   A0A1Y1MQ85   A0A1Y1MRZ4   A0A182M3Y9   A0A336LVW2   W8B3X5   A0A1B6M0G0   A0A0Q9WKY0   A0A0Q9WL38   A0A182G7G0   A0A336M4C3   B4MDD0   A0A034VBV9   W8BDV1   V9I653   B4N0N6   A0A0R1DK60   A0A0J9QVH7   A0A0R3NRK4   Q967D7-5   W8AHL1   A0A139WJV7   A0A0M3QT07   A0A0R1DJ34   B4I374   Q967D7-2   E1JHS9   Q967D7-4   A0A0J9QWH3   A0A0R3NY41   A0A0R3NRT6   A0A139WJK5   A0A0R1DJ77   A0A3B0JZJ0   Q967D7   E1JHT0   A0A1B6CWC2   A0A1W4UQ05   A0A1W4V3Y0   A0A0A1XG79   A0A0P9A3B3   B4JD36   A0A1B6DNG5   A0A1W4UQJ1   A0A0A1X297   A0A0R1DQD2   A0A0Q5W9B6   A0A1W4UQI6   A0A1W4V2S8   W5JFI5   A0A1W4V2G1   A0A0J9TF92   A0A0R3NXQ3   T1HFR6   A0A0Q5W961   A0A0P8XE88   A0A1B6E919   A0A1B6C0M6   A0A0A1X554   A0A0R1DJD6   A0A0Q5WKV0   A0A0Q5WID7   A0A0C9R6F7   A0A0C9S214   B4NYI7   A0A0R1DQN2   A0A0R3NRN3   A0A0J9QVG8   A0A0R3NWW3   M9PCI8   E0VN01  

Pubmed

22118469    26354079    12364791    17510324    24438588    28004739    + More
25244985    24495485    17994087    26483478    25348373    17550304    22936249    15632085    11312296    10731132    12537572    24174674    18362917    19820115    12537568    12537573    12537574    16110336    17569856    17569867    26109357    26109356    25830018    20920257    23761445    20566863   

EMBL

KY350198    AQZ26950.1    NWSH01003437    PCG66306.1    AGBW02010564    OWR48280.1    + More
RSAL01000116    RVE46867.1    PCG66305.1    KQ459592    KPI96763.1    KQ460845    KPJ12031.1    ODYU01001360    SOQ37426.1    PCG66303.1    AAAB01008964    EAA12846.4    ATLV01014971    ATLV01014972    KE524999    KFB39724.1    CH477394    EAT41900.1    APCN01002500    GEZM01024234    JAV87842.1    GEZM01024223    JAV87859.1    CVRI01000044    CRK96838.1    GEZM01024232    JAV87845.1    GEZM01024228    JAV87850.1    KQ435102    KZC14664.1    GEZM01024229    JAV87849.1    GEZM01024230    JAV87848.1    AXCM01008531    UFQT01000144    SSX20849.1    GAMC01018609    JAB87946.1    GEBQ01010558    JAT29419.1    CH940661    KRF85516.1    KRF85517.1    JXUM01008362    JXUM01008363    JXUM01008364    KQ560259    KXJ83503.1    SSX20848.1    EDW71191.2    GAKP01019355    JAC39597.1    GAMC01018611    JAB87944.1    JR035185    AEY56260.1    CH963920    EDW77649.2    CM000157    KRJ97262.1    CM002910    KMY88043.1    CH379059    KRT03730.1    AJ312132    AJ312133    AJ312134    AJ312135    AE014134    BT010247    GAMC01018610    JAB87945.1    KQ971338    KYB28097.1    CP012523    ALC38083.1    KRJ97260.1    CH480820    EDW54219.1    ACZ94160.1    KMY88039.1    KRT03731.1    KRT03722.1    KYB28096.1    KRJ97258.1    OUUW01000004    SPP79099.1    ACZ94159.1    AGB92556.1    GEDC01019570    JAS17728.1    GBXI01004372    JAD09920.1    CH902620    KPU73026.1    CH916368    EDW04280.1    GEDC01010089    JAS27209.1    GBXI01008828    JAD05464.1    KRJ97264.1    CH954177    KQS70076.1    ADMH02001548    ETN62103.1    KMY88040.1    KRT03728.1    ACPB03018591    KQS70081.1    KPU73025.1    GEDC01002875    JAS34423.1    GEDC01030374    GEDC01023640    GEDC01014706    JAS06924.1    JAS13658.1    JAS22592.1    GBXI01008427    JAD05865.1    KRJ97256.1    KQS70082.1    KQS70078.1    GBYB01003570    JAG73337.1    GBYB01014906    JAG84673.1    EDW87620.1    KRJ97254.1    KRJ97255.1    KRJ97259.1    KRJ97257.1    KRT03723.1    KMY88042.1    KRT03725.1    AGB92555.1    DS235331    EEB14757.1   

Proteomes

UP000218220    UP000007151    UP000283053    UP000053268    UP000053240    UP000007062    + More
UP000030765    UP000008820    UP000075885    UP000075880    UP000069272    UP000075840    UP000075884    UP000183832    UP000075903    UP000075900    UP000076407    UP000076408    UP000076502    UP000075883    UP000008792    UP000069940    UP000249989    UP000007798    UP000002282    UP000001819    UP000000803    UP000007266    UP000092553    UP000001292    UP000268350    UP000192221    UP000007801    UP000001070    UP000008711    UP000000673    UP000015103    UP000009046   

PRIDE

Q967D7    M9PCI8   

Pfam

PF07686   V-set        + More
PF07679   I-set
PF00041   fn3
PF13895   Ig_2
PF00151   Lipase
PF06859   Bin3

Interpro

IPR013106   Ig_V-set        + More
IPR036179   Ig-like_dom_sf       
IPR003598   Ig_sub2       
IPR013783   Ig-like_fold       
IPR003961   FN3_dom       
IPR003599   Ig_sub       
IPR007110   Ig-like_dom       
IPR036116   FN3_sf       
IPR013098   Ig_I-set       
IPR013818   Lipase/vitellogenin       
IPR029058   AB_hydrolase       
IPR033906   Lipase_N       
IPR000734   TAG_lipase       
IPR024160   BIN3_SAM-bd_dom       
IPR029063   SAM-dependent_MTases       
IPR010675   Bin3_C       

SUPFAM

SSF48726   SSF48726        + More
SSF49265   SSF49265       
SSF53474   SSF53474       
SSF53335   SSF53335       

Gene 3D

2.60.40.10     3.40.50.1820    

CDD

cd00063  FN3
cd00707  Pancreat_lipase_like

ProteinModelPortal

A0A1U9XRB3   A0A2A4J3J1   A0A212F3G4   A0A3S2NX96   A0A2A4J2M0   A0A194PUV0   + More
A0A194R837   A0A2H1V9G2   A0A2A4J4G3   Q7Q3K8   A0A1S4J7Q9   A0A1S4GWQ1   A0A1S4FDQ5   A0A084VP30   Q0IF39   A0A182PJ73   A0A182JK20   A0A182F4L4   A0A182HV77   A0A1Y1MQA9   A0A182NE36   A0A1Y1MQ97   A0A1J1ID06   A0A182UV49   A0A182RBL8   A0A1Y1MTP8   A0A1Y1MTN2   A0A182WT84   A0A182YGU3   A0A154PTC6   A0A1Y1MQ85   A0A1Y1MRZ4   A0A182M3Y9   A0A336LVW2   W8B3X5   A0A1B6M0G0   A0A0Q9WKY0   A0A0Q9WL38   A0A182G7G0   A0A336M4C3   B4MDD0   A0A034VBV9   W8BDV1   V9I653   B4N0N6   A0A0R1DK60   A0A0J9QVH7   A0A0R3NRK4   Q967D7-5   W8AHL1   A0A139WJV7   A0A0M3QT07   A0A0R1DJ34   B4I374   Q967D7-2   E1JHS9   Q967D7-4   A0A0J9QWH3   A0A0R3NY41   A0A0R3NRT6   A0A139WJK5   A0A0R1DJ77   A0A3B0JZJ0   Q967D7   E1JHT0   A0A1B6CWC2   A0A1W4UQ05   A0A1W4V3Y0   A0A0A1XG79   A0A0P9A3B3   B4JD36   A0A1B6DNG5   A0A1W4UQJ1   A0A0A1X297   A0A0R1DQD2   A0A0Q5W9B6   A0A1W4UQI6   A0A1W4V2S8   W5JFI5   A0A1W4V2G1   A0A0J9TF92   A0A0R3NXQ3   T1HFR6   A0A0Q5W961   A0A0P8XE88   A0A1B6E919   A0A1B6C0M6   A0A0A1X554   A0A0R1DJD6   A0A0Q5WKV0   A0A0Q5WID7   A0A0C9R6F7   A0A0C9S214   B4NYI7   A0A0R1DQN2   A0A0R3NRN3   A0A0J9QVG8   A0A0R3NWW3   M9PCI8   E0VN01  

PDB

3B43     E-value=9.01792e-29,     Score=319

KEGG

101746344    K22656 immunoglobulin superfamily member 9B | (RefSeq) protein turtle

GO

GO:0016021   GO:0006629   GO:0005576   GO:0052689   GO:0008168   GO:0048814   GO:0070593   GO:0007629   GO:0007411   GO:0016199   GO:0007414   GO:0008039   GO:0030537   GO:0098632   GO:0045467   GO:0005887   GO:0007638   GO:0008344   GO:0005515   GO:0046856   GO:0000166   GO:0006412   GO:0005852   GO:0006446   GO:0043022   GO:0005488   GO:0003707   GO:0051537  

Subcellular location

Secreted  
Membrane  

SignalP

Position:   1 - 27,         Likelihood:  0.992985

 

 

Length:

798

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

23.15249

Exp number, first 60 AAs:

0.28583

Total prob of N-in:

0.01389

outside

1  -  752

TMhelix

753  -  775

inside

776  -  798

 

 

Pi

22.555375

Theta

18.845785

Tajima's D

0.02776

CLR

19.270444

CSRT

0.381030948452577

Interpretation

Uncertain