Gene

KWMTBOMO07366

Pre Gene Modal

BGIBMGA010683

Annotation

PREDICTED:_WD_repeat-containing_and_planar_cell_polarity_effector_protein_fritz_homolog_isoform_X2_[Bombyx_mori]

Location

Bomo_Chr12(+):11359680-11368567      View in EpiBrowser

Full name

WD repeat-containing and planar cell polarity effector protein fritz      

Location in the cell

Mitochondrial   Reliability : 1.432 PlasmaMembrane   Reliability : 1.865

CDS

ATGATAAATTACCATATCAAATATATAACATCCTCTGAAACATTACACCTTAAAAGTAGCGACTTCAAATGTTTCAAGTATGAAACGAAAAAACGCGCTGAAGAATCAATATACGGTTCAAGTAAAAGGAATTACTGTGAATTGCGTGGTGGACATTGGCGGTCACCTCGCCCGCGGCAAATACAAAAACTGGAATCCAAATTACGTGATAAAAATGTGATAGCTTGTGAATGGACTAACGAGCAGCTTGTAACTATTATATTCTCATCAGGGGTCATAGCCTACCTAACAGTTAAGCAAGATACTTTAGACATTTCACAGATATTATTTGATAGATATTTTGTAGGCAAACTTCCTGGACACACTGTAACAAATGTTGTTTTATCTAAGTCCCACATATTATTCACATTTGTGGACCGAATAGCAACATTAGTGACATTTAAAAAAAAGACATCAAATGTGCCATGTAAAATAGTTGATAAAGAACCTCTGTTACAAACTATTGAACTTGGTGGAGCTTCACGTCGCACAGACAGACATGTCTCTTGGTGTGAAAATAATGATTTATTATGGACTCTAGTCTGGAGTGTCACTCCTGCTGAACCAGCTCCTTGGAGTCCTGTACTAGAAGATCATGCAAATTTACATCTGTATCAAATCAGCGGACAAAACATGAACCTACTTGTTTACCATCGGTTAGAAAATGAAACATTAGTTGCAGAGCTTTCGCATAAAAGGGATCGGATCATACATATTGTGGACCAAACTGCATCACAAAAGAACTGCGTGACGTTGCGCTGGATGAGATACGAAGTGACGGAGAGTCATACGCCGAAATTGCAAGTGTCCCCGGAGAACGTGACGCGGCTGGCACTGCCGGCGCCGGCGCGGGTCGCTCGCAGGGCGCCGTGCGACTCGCGCCTCGTCGCAGCCTGCATCGACGGCTCCGTGCACGTGGCGCACCACACCGCGGGACTCACGCACTCAACTAAAGCCGGCTTCATCGCGACGGACGTGCGATGGGCTGGCGAATTAGTGATAGCCATTGAAGAGAATGGAAGGATTCAATGCTTCGACCGCGCCCTCTCGCTACTCAATCATCACATCAAGTTTCTAGATTTAGCCGCGGATCTGAGCGATGCGAAAAGAATGAAGGTGCTCGCAACCCTGAATGCGAAATGTGGTCCCATTTTGCTGGCAACATTCACTGGCGGTCCGCTCGCATTAATTCACATCACGCACCCACGTCTTATAACGGCGTGGATAAGGGCTCGTCGGACGTCGAGTGCAGTAGCTTTGCTGCGGGCGATGGATTGGGAACATGAAGGAAATGATTGCCTATGGGCAGTCAATAAACTTATCTGCGCTTCTCTCAGGAGCGGGGCAGGTATTATATTTGATTGGTGTTCTCTCTCTCTCTCTCCTCGACTTTCGTAA

Protein

MINYHIKYITSSETLHLKSSDFKCFKYETKKRAEESIYGSSKRNYCELRGGHWRSPRPRQIQKLESKLRDKNVIACEWTNEQLVTIIFSSGVIAYLTVKQDTLDISQILFDRYFVGKLPGHTVTNVVLSKSHILFTFVDRIATLVTFKKKTSNVPCKIVDKEPLLQTIELGGASRRTDRHVSWCENNDLLWTLVWSVTPAEPAPWSPVLEDHANLHLYQISGQNMNLLVYHRLENETLVAELSHKRDRIIHIVDQTASQKNCVTLRWMRYEVTESHTPKLQVSPENVTRLALPAPARVARRAPCDSRLVAACIDGSVHVAHHTAGLTHSTKAGFIATDVRWAGELVIAIEENGRIQCFDRALSLLNHHIKFLDLAADLSDAKRMKVLATLNAKCGPILLATFTGGPLALIHITHPRLITAWIRARRTSSAVALLRAMDWEHEGNDCLWAVNKLICASLRSGAGIIFDWCSLSLSPRLS

Description

Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Functions cell autonomously to regulate wing cell hair polarity and number.

Similarity

Belongs to the WD repeat fritz family.

Keywords

Cell membrane   Cell projection   Cilium   Complete proteome   Cytoplasm   Cytoskeleton   Membrane   Reference proteome   Repeat   WD repeat  

Feature

chain  WD repeat-containing and planar cell polarity effector protein fritz

Uniprot

A0A2H1VC14   A0A2A4JQE4   A0A194R2W3   A0A194PI11   A0A212F3G6   A0A0L7KSB5   + More
A0A067QKD4   A0A232FBP3   A0A2P8XNQ3   A0A3L8DDZ7   A0A026W1E4   A0A1B6D3B8   A0A2A3ESR1   A0A1B6M0F5   A0A087ZNQ9   A0A0L7R2D7   K7IUM7   A0A0M9A640   A0A023EY85   A0A1J1I9K5   A0A195FQ98   A0A1B6K3G6   A0A2J7RCS2   A0A182GY43   A0A195BWH4   A0A158NV12   E2B3D2   A0A182GRW7   Q16RV9   A0A0P4WSM0   B0X1U1   F4WXK5   A0A1S4FRA8   A0A195DB22   A0A182F840   A0A2M4B9X3   A0A195CRK6   A0A151WSL3   E2A4F9   A0A182RH50   A0A182VQ23   A0A182M0J0   A0A0C9QFR8   A0A0C9RJC5   A0A182SX86   A0A182QNS5   A0A182UBS8   A0A084VK03   A0A182K5W9   A0A182Y4Q5   A0A182J9D5   A0A2M3Z2S1   W5J3B6   A0A182PJN4   A0A2M4BA06   Q7QKB4   A0A1B0GKH0   A0A2M4A8I4   A0A182X3A2   A0A2M4A913   A0A2M4A8M0   A0A2M4A8R9   A0A182HZF8   A0A182NMN6   A0A182VEH6   A0A3R7PQ15   T1HMQ0   T1JGE4   A0A336MF77   A0A1S3HFW6   A0A2R2MIN4   A0A310SEJ4   A0A147BGI5   A0A0L8I2U0   A0A146KW75   A0A0A9WNR8   A0A1W4XUH0   A0A0K8VEW9   A0A0A1X9N6   A0A0K8WD26   A0A0K8TWR6   B4KGC5   A7S6S2   A0A3B0K319   A0A293MFF2   B4MW67   Q29MT0   B4G8S5   A0A034VFY6   A0A2R5LDZ0   B4IDB2   A0A0J9QTU7   B3N8W9   M9PBR4   Q9VQ36   M9PE00   A0A0L0C708  

Pubmed

26354079    22118469    26227816    24845553    28648823    29403074    + More
30249741    24508170    20075255    24945155    26483478    21347285    20798317    17510324    21719571    24438588    25244985    20920257    23761445    12364791    29652888    26823975    25401762    25830018    17994087    17615350    15632085    25348373    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    15654087    26108605   

EMBL

ODYU01001559    SOQ37942.1    NWSH01000899    PCG73630.1    KQ460845    KPJ12037.1    + More
KQ459603    KPI92688.1    AGBW02010564    OWR48275.1    JTDY01006531    KOB65929.1    KK853336    KDR08346.1    NNAY01000458    OXU28251.1    PYGN01001635    PSN33632.1    QOIP01000009    RLU18526.1    KK107519    EZA49406.1    GEDC01017128    JAS20170.1    KZ288186    PBC34737.1    GEBQ01010582    JAT29395.1    KQ414666    KOC64993.1    AAZX01006018    KQ435733    KOX77236.1    GAPW01000089    JAC13509.1    CVRI01000045    CRK96967.1    KQ981335    KYN42596.1    GECU01001721    JAT05986.1    NEVH01005883    PNF38637.1    JXUM01096906    JXUM01096907    JXUM01096908    JXUM01096909    KQ564301    KXJ72458.1    KQ976401    KYM92630.1    ADTU01026823    ADTU01026824    GL445323    EFN89810.1    JXUM01083428    KQ563376    KXJ73952.1    CH477694    EAT37187.1    GDRN01064892    JAI64763.1    DS232269    EDS38819.1    GL888425    EGI61075.1    KQ981082    KYN09614.1    GGFJ01000696    MBW49837.1    KQ977444    KYN02744.1    KQ982769    KYQ50912.1    GL436635    EFN71706.1    AXCM01002118    GBYB01013343    JAG83110.1    GBYB01013342    JAG83109.1    AXCN02001214    ATLV01014013    ATLV01014014    ATLV01014015    KE524927    KFB38297.1    GGFM01002063    MBW22814.1    ADMH02002112    ETN58842.1    GGFJ01000753    MBW49894.1    AAAB01008799    EAA03756.5    AJWK01028865    GGFK01003792    MBW37113.1    GGFK01003787    MBW37108.1    GGFK01003780    MBW37101.1    GGFK01003875    MBW37196.1    APCN01001974    QCYY01002024    ROT73495.1    ACPB03003866    JH432201    UFQT01001120    SSX29004.1    KQ760645    OAD59680.1    GEGO01005526    JAR89878.1    KQ416683    KOF95783.1    GDHC01019579    JAP99049.1    GBHO01034165    GBHO01011236    JAG09439.1    JAG32368.1    GDHF01014906    JAI37408.1    GBXI01006278    JAD08014.1    GDHF01003360    JAI48954.1    GDHF01033395    JAI18919.1    CH933807    EDW11112.1    DS469589    EDO40576.1    OUUW01000006    SPP82300.1    GFWV01014875    MAA39604.1    CH963857    EDW75937.1    CH379060    EAL33613.1    CH479180    EDW28755.1    GAKP01017533    JAC41419.1    GGLE01003586    MBY07712.1    CH480829    EDW45538.1    CM002910    KMY87507.1    CH954177    EDV57369.1    AE014134    AGB92416.1    BT004832    AGB92417.1    JRES01000827    KNC28027.1   

Proteomes

UP000218220    UP000053240    UP000053268    UP000007151    UP000037510    UP000027135    + More
UP000215335    UP000245037    UP000279307    UP000053097    UP000242457    UP000005203    UP000053825    UP000002358    UP000053105    UP000183832    UP000078541    UP000235965    UP000069940    UP000249989    UP000078540    UP000005205    UP000008237    UP000008820    UP000002320    UP000007755    UP000078492    UP000069272    UP000078542    UP000075809    UP000000311    UP000075900    UP000075920    UP000075883    UP000075901    UP000075886    UP000075902    UP000030765    UP000075881    UP000076408    UP000075880    UP000000673    UP000075885    UP000007062    UP000092461    UP000076407    UP000075840    UP000075884    UP000075903    UP000283509    UP000015103    UP000085678    UP000053454    UP000192223    UP000009192    UP000001593    UP000268350    UP000007798    UP000001819    UP000008744    UP000001292    UP000008711    UP000000803    UP000037069   

PRIDE

M9PBR4    Q9VQ36   

Pfam

PF11768   Frtz        + More
PF02238   COX7a
PF05712   MRG
PF11717   Tudor-knot
PF04032   Rpr2
PF02597   ThiS
PF10260   SAYSvFN

Interpro

IPR024511   Frtz        + More
IPR036539   Cyt_c_oxidase_su7a_sf       
IPR003177   Cytc_oxidase_su7a_met       
IPR039297   COX7a       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR036322   WD40_repeat_dom_sf       
IPR002014   VHS_dom       
IPR038217   MRG_C_sf       
IPR026541   MRG_dom       
IPR000953   Chromo/chromo_shadow_dom       
IPR025995   Tudor-knot       
IPR016197   Chromo-like_dom_sf       
IPR007175   Rpr2       
IPR036116   FN3_sf       
IPR002110   Ankyrin_rpt       
IPR013783   Ig-like_fold       
IPR020683   Ankyrin_rpt-contain_dom       
IPR036770   Ankyrin_rpt-contain_sf       
IPR019387   Uncharacterised_SAYSvFN       
IPR003749   ThiS/MoaD-like       
IPR012675   Beta-grasp_dom_sf       
IPR016155   Mopterin_synth/thiamin_S_b       

SUPFAM

SSF81419   SSF81419        + More
SSF50978   SSF50978       
SSF54160   SSF54160       
SSF49265   SSF49265       
SSF48403   SSF48403       
SSF54285   SSF54285       

Gene 3D

4.10.91.10     2.130.10.10     1.10.274.30     1.25.40.20     2.60.40.10     3.10.20.30    

CDD

cd00928  Cyt_c_Oxidase_VIIa
cd00024  CHROMO
cd00204  ANK

ProteinModelPortal

A0A2H1VC14   A0A2A4JQE4   A0A194R2W3   A0A194PI11   A0A212F3G6   A0A0L7KSB5   + More
A0A067QKD4   A0A232FBP3   A0A2P8XNQ3   A0A3L8DDZ7   A0A026W1E4   A0A1B6D3B8   A0A2A3ESR1   A0A1B6M0F5   A0A087ZNQ9   A0A0L7R2D7   K7IUM7   A0A0M9A640   A0A023EY85   A0A1J1I9K5   A0A195FQ98   A0A1B6K3G6   A0A2J7RCS2   A0A182GY43   A0A195BWH4   A0A158NV12   E2B3D2   A0A182GRW7   Q16RV9   A0A0P4WSM0   B0X1U1   F4WXK5   A0A1S4FRA8   A0A195DB22   A0A182F840   A0A2M4B9X3   A0A195CRK6   A0A151WSL3   E2A4F9   A0A182RH50   A0A182VQ23   A0A182M0J0   A0A0C9QFR8   A0A0C9RJC5   A0A182SX86   A0A182QNS5   A0A182UBS8   A0A084VK03   A0A182K5W9   A0A182Y4Q5   A0A182J9D5   A0A2M3Z2S1   W5J3B6   A0A182PJN4   A0A2M4BA06   Q7QKB4   A0A1B0GKH0   A0A2M4A8I4   A0A182X3A2   A0A2M4A913   A0A2M4A8M0   A0A2M4A8R9   A0A182HZF8   A0A182NMN6   A0A182VEH6   A0A3R7PQ15   T1HMQ0   T1JGE4   A0A336MF77   A0A1S3HFW6   A0A2R2MIN4   A0A310SEJ4   A0A147BGI5   A0A0L8I2U0   A0A146KW75   A0A0A9WNR8   A0A1W4XUH0   A0A0K8VEW9   A0A0A1X9N6   A0A0K8WD26   A0A0K8TWR6   B4KGC5   A7S6S2   A0A3B0K319   A0A293MFF2   B4MW67   Q29MT0   B4G8S5   A0A034VFY6   A0A2R5LDZ0   B4IDB2   A0A0J9QTU7   B3N8W9   M9PBR4   Q9VQ36   M9PE00   A0A0L0C708  

KEGG

101737102    K22863 WD repeat-containing and planar cell polarity effector protein | (RefSeq) WD repeat-containin

GO

GO:0004129   GO:0005746   GO:0016021   GO:0005623   GO:0006886   GO:0016874   GO:0045184   GO:0035320   GO:0005886   GO:0005929   GO:0005856   GO:0005737  

PANTHER

PTHR13667  

Subcellular location

Cell membrane  
Cytoplasm  
Cytoskeleton  
Cilium axoneme  

Length:

478

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.59668

Exp number, first 60 AAs:

0

Total prob of N-in:

0.05989

outside

1  -  478

 

 

Pi

14.808654

Theta

15.443063

Tajima's D

0.045513

CLR

0.365668

CSRT

0.392780360981951

Interpretation

Uncertain