Gene

KWMTBOMO07363  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010605

Annotation

pheromone_biosynthesis_activating_neuropeptide_receptor_isoform_A_[Bombyx_mori]

Location

Bomo_Chr12(-):11265099-11271019      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.982

CDS

ATGATGGCAGATGAAACCGTCAACATGGAAATGCTCGAGAACAATTTGCTGAATGTCACGAACGTGACAGACCAATCTTCTGCGTACAGTGAATCCTACCCATTACATCTGCTAGTACCATTAAGTGTTACGTACGCTGTCATATTCATAGTCGGGATCTTAGGGAATACAAGCACATGCGTGGTCATAGCGCGTAACCGCTCCATGCACACCGCCACTAACTTCTACCTCTTCAGTCTTGCTATCTCCGATATAATACTCCTTGTGTGCGGTCTGCCCTTAGAATTGTATCGCTTGTGGAATCCGTTTACGTACCCCCTCGGTGAGGCGCAATGTATCACGATAGGTCTGGCGTCTGAAACGTCTGCGAACGCAACCGTATTGACTATTACGGCATTCACTATGGAGCGATACATTGCTATATGTAGACCGTTCATGTCGCATACCATGTCGAAGCTTTCACGGGCTGTGCGATTTATTATTGCTATATGGGTGTTCGCGCTGTGTACGGCGGTACCTCAAGCGATGCAATTCGGTATAGTGTCTTACGTTGAAAACGGACAGAGCATGAGTGCTTGTACTGTGAAAGGACCTGGTGTGCACCAAGTGTTTGTCATTTCGAGTTTTGTTTTCTTCGTTGTACCTATGTCGGTTATATCGGTGTTGTACGCGTTGATAGGGCTCAAGTTACGTACGTCTCGTATTTTGCATCCCGTTAAGAAGCTGTCATTAGATAGCAATGAGAGGCCTGGCGCGCACACACCGTACAGAAACGGAAGCTCACAGAGGAGGGTCATCAGAATGCTCGTTGCTGTGGCGCTGTCGTTTTTCATCTGTTGGGCTCCATTTCACGTGCAGAGGCTTCTCGCGATTTATGGGAAGAGTTTGGAACATCCGTCTGATACATTTTATCTGGTGTACATAGTGTTGACCTTTTTATCTGGAGTCCTGTATTTCCTTTCGACGGCTATTAATCCATTTCTCTACAACATAATGTCGAACAAATTCAGGAACGCTTTCAAGAATTGA

Protein

MMADETVNMEMLENNLLNVTNVTDQSSAYSESYPLHLLVPLSVTYAVIFIVGILGNTSTCVVIARNRSMHTATNFYLFSLAISDIILLVCGLPLELYRLWNPFTYPLGEAQCITIGLASETSANATVLTITAFTMERYIAICRPFMSHTMSKLSRAVRFIIAIWVFALCTAVPQAMQFGIVSYVENGQSMSACTVKGPGVHQVFVISSFVFFVVPMSVISVLYALIGLKLRTSRILHPVKKLSLDSNERPGAHTPYRNGSSQRRVIRMLVAVALSFFICWAPFHVQRLLAIYGKSLEHPSDTFYLVYIVLTFLSGVLYFLSTAINPFLYNIMSNKFRNAFKN

Similarity

Belongs to the G-protein coupled receptor 1 family.

Uniprot

H2CY19   Q65YS4   H2CY20   C9WBN0   C9WBN2   C9WBN3   + More
C9WBN1   H2CY18   Q27HC8   A0A0U1ZAZ7   A0A1X9PPU6   G5DFC3   Q6VYH4   B0FYP0   H2CY23   H2CY27   A0A1X9PPU5   A0A1X9PQN0   H2CY29   Q5ICC7   A7YII1   H2CY25   A0A2A4JLW4   G3KFK9   H2CY24   H2CY28   L7P6E7   A0A068FL22   A0A1W5K2U9   A7YII3   B1NPT7   A0A345ANM8   R4LCH4   R4L363   A0A3Q9NR23   R4LB27   A0A194PH11   A0A194R2M0   A0A212F409   A0A0S1YDK1   A0A0S1YDX8   H2CY26   H2CY22   H9JM53   A0A2R4PCU9   Q1X7I2   A0A1Q3G5H0   A0A1Q3G5K1   A0A0L7KLR9   A0A2H1V5B2   A1A686   E0VE49   A1BXU1   A0A154PD71   A0A182I9Y5   A0A182MZU4   Q3YL79   A7XII4   Q16L21   A0A1S4FXM4   A0A182LD30   A0A182X7F4   A0A182H311   A0A182W5Y9   D6X3X9   A0A084VAB3   A0A0C9RY41   K7J0U7   L0APC6   Q7RTK4   B1Q2A1   Q7RTK3   B1Q298   A0A0J7KY79   A0A0L7RGI4   A0A026W4S0   A0A151JSI6   F4W5B1   A0A1Y1KZF9   A0A195BTH3   A0A158NYT3   A0A195FUY4   A0A182MG56   A0A0P6J0T1   W5JN91   A0A182Q2B0   A0A151X3C0   A0A182QPY3   A0A182RPJ3   A0A195CW36   F5HKX9   A7XII7   A0A182VN76   A0A182FJV1   A0A182FBP5   A0A1B0CG71   E2AX14   A0A1S4F5I7   Q0IG04   A0A182YH31  

Pubmed

22654850    15358772    17379458    23850474    12888624    20665850    + More
17328713    18243415    26385554    23551811    26354079    22118469    19121390    21220012    26227816    17070981    20566863    16054112    17709098    17510324    20966253    26483478    18362917    19820115    25348027    24438588    20075255    12951076    12364791    14747013    17210077    24508170    30249741    21719571    28004739    21347285    26999592    20920257    23761445    20798317    25244985   

EMBL

JN228347    AEX15646.1    JN228349    AB181298    AEX15640.1    BAD44726.1    + More
JN228348    AEX15643.1    FJ240221    ACQ90219.1    FJ240223    ACQ90221.1    FJ240224    ACQ90222.1    FJ240222    ACQ90220.1    JN228346    AEX31546.1    DQ407742    ABD52277.1    KM023791    AJW32184.1    KX831609    ARO85771.1    JN648826    AEQ33641.1    AY319852    AAP93921.1    EU365878    ABY62317.2    JN228351    AEX15647.1    JN228355    AEX15648.1    KX831611    ARO85773.1    KX831610    ARO85772.1    JN228357    AEX15642.1    AY792036    AAW47417.1    EU000525    ABU93812.1    JN228353    AEX15641.1    NWSH01001040    PCG72971.1    JN206677    AEO17028.2    JN228352    AEX15644.1    JN228356    AEX15645.1    JQ255024    AFP19101.1    KJ622075    AID66638.1    KR069142    AMN09327.1    EU000526    ABU93813.1    EU000527    ABV58013.1    MF770988    AXF38050.1    JX500423    AGL12068.1    JX500421    AGL12066.1    MK288169    AZT88556.1    JX500422    AGL12067.1    KQ459603    KPI92686.1    KQ460845    KPJ12038.1    AGBW02010456    OWR48476.1    KT031039    ALM88337.1    KT031040    ALM88338.1    JN228354    AEX31548.1    JN228350    AEX31547.1    BABH01033507    KY987648    AVX48910.1    AY974334    JN410825    AAY34744.1    AEP25401.1    GEYN01000201    JAV44788.1    GEYN01000200    JAV44789.1    JTDY01008976    KOB64247.1    ODYU01000757    SOQ36023.1    BK005718    DAA05842.1    DS235088    EEB11655.1    DQ869051    ABJ09598.1    KQ434878    KZC09845.1    APCN01001075    DQ103706    AAZ43087.1    AY900218    AAX84797.1    CH477926    EAT35008.2    JXUM01106423    JXUM01106424    KQ565054    KXJ71406.1    KJ435305    KQ971379    AIZ00520.1    EEZ97728.2    ATLV01003054    KE524109    KFB34907.1    GBYB01012826    JAG82593.1    JX657040    AFZ77039.1    BK001383    DAA01375.1    AAAB01008847    EAA06972.3    BK001384    DAA01376.1    AAAB01008879    EAA08454.4    LBMM01001947    KMQ95497.1    KQ414596    KOC69923.1    KK107419    QOIP01000003    EZA51023.1    RLU25067.1    KQ978543    KYN30205.1    GL887645    EGI70561.1    GEZM01068835    JAV66744.1    KQ976407    KYM91401.1    ADTU01004262    ADTU01004263    ADTU01004264    KQ981276    KYN43679.1    AXCM01000712    AXCM01000713    GDUN01000345    JAN95574.1    ADMH02000618    ETN65601.1    AXCN02000293    KQ982566    KYQ54764.1    AXCN02002524    KQ977220    KYN04891.1    EGK96940.1    AY900219    AAX84798.1    AJWK01010799    GL443495    EFN62034.1    CH477281    EAT44919.2   

Proteomes

UP000218220    UP000053268    UP000053240    UP000007151    UP000005204    UP000037510    + More
UP000009046    UP000076502    UP000075840    UP000075884    UP000008820    UP000075882    UP000076407    UP000069940    UP000249989    UP000075920    UP000007266    UP000030765    UP000002358    UP000007062    UP000036403    UP000053825    UP000053097    UP000279307    UP000078492    UP000007755    UP000078540    UP000005205    UP000078541    UP000075883    UP000000673    UP000075886    UP000075809    UP000075900    UP000078542    UP000075903    UP000069272    UP000092461    UP000000311    UP000076408   

PRIDE

H2CY19    Q65YS4    H2CY20    H2CY18    H9JM53   

Pfam

PF00001   7tm_1

Interpro

IPR000276   GPCR_Rhodpsn        + More
IPR017452   GPCR_Rhodpsn_7TM       
IPR005390   NeuromedU_rcpt       

ProteinModelPortal

H2CY19   Q65YS4   H2CY20   C9WBN0   C9WBN2   C9WBN3   + More
C9WBN1   H2CY18   Q27HC8   A0A0U1ZAZ7   A0A1X9PPU6   G5DFC3   Q6VYH4   B0FYP0   H2CY23   H2CY27   A0A1X9PPU5   A0A1X9PQN0   H2CY29   Q5ICC7   A7YII1   H2CY25   A0A2A4JLW4   G3KFK9   H2CY24   H2CY28   L7P6E7   A0A068FL22   A0A1W5K2U9   A7YII3   B1NPT7   A0A345ANM8   R4LCH4   R4L363   A0A3Q9NR23   R4LB27   A0A194PH11   A0A194R2M0   A0A212F409   A0A0S1YDK1   A0A0S1YDX8   H2CY26   H2CY22   H9JM53   A0A2R4PCU9   Q1X7I2   A0A1Q3G5H0   A0A1Q3G5K1   A0A0L7KLR9   A0A2H1V5B2   A1A686   E0VE49   A1BXU1   A0A154PD71   A0A182I9Y5   A0A182MZU4   Q3YL79   A7XII4   Q16L21   A0A1S4FXM4   A0A182LD30   A0A182X7F4   A0A182H311   A0A182W5Y9   D6X3X9   A0A084VAB3   A0A0C9RY41   K7J0U7   L0APC6   Q7RTK4   B1Q2A1   Q7RTK3   B1Q298   A0A0J7KY79   A0A0L7RGI4   A0A026W4S0   A0A151JSI6   F4W5B1   A0A1Y1KZF9   A0A195BTH3   A0A158NYT3   A0A195FUY4   A0A182MG56   A0A0P6J0T1   W5JN91   A0A182Q2B0   A0A151X3C0   A0A182QPY3   A0A182RPJ3   A0A195CW36   F5HKX9   A7XII7   A0A182VN76   A0A182FJV1   A0A182FBP5   A0A1B0CG71   E2AX14   A0A1S4F5I7   Q0IG04   A0A182YH31  

PDB

4BWB     E-value=6.59155e-26,     Score=291

KEGG

692524    K05052 neuromedin U receptor 1 | (RefSeq) Pbanr; pheromone biosynthesis activating neuropeptide rece

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0001607   GO:0004930   GO:0007218   GO:0050254   GO:0007186   GO:0005852   GO:0006446   GO:0043022   GO:0005488   GO:0003707   GO:0051537  

Length:

342

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

157.31387

Exp number, first 60 AAs:

20.93136

Total prob of N-in:

0.00280

POSSIBLE N-term signal

sequence

outside

1  -  32

TMhelix

33  -  55

inside

56  -  74

TMhelix

75  -  97

outside

98  -  111

TMhelix

112  -  134

inside

135  -  158

TMhelix

159  -  181

outside

182  -  203

TMhelix

204  -  226

inside

227  -  268

TMhelix

269  -  291

outside

292  -  305

TMhelix

306  -  328

inside

329  -  342

 

 

Pi

2.65031

Theta

5.890346

Tajima's D

-1.590209

CLR

0.248671

CSRT

0.0435978201089946

Interpretation

Uncertain