Gene

KWMTBOMO07360

Annotation

neuropeptide_receptor_A2_[Bombyx_mori]

Location

Bomo_Chr12(+):11181648-11187405      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.99

CDS

ATGATGGAACCAAATAATAGCGAATATGAGAATAATTCTTATATTACATTTTTCGGACCCGTGGGGATGGCTTTTTATGACAACGGCCAGGTCTTAGAAGATAGCCTCACAGTCAAAATCATATTGAGTATTATACTGGCTGTTATAATGATTCTGAGTTTAATCGGAAATGGTTGTACTTGTGCTGTGATCGCTCGCAATCGTTCTATGCGAACTCCGACTAACTGCTATTTATTCAACCTTGCAATTACCGACCTGTTCATGGCTTTATTTGTGCCAATAGACATTTACATCATTTGGATCCCTGAATTCTACCCATTGGGGGAAGTGGGCTGCCGTCTGCATTTCGTGCTGTGGGATTGTCTTAGTAATTGTAGCCTGCTGATTATAACCGCGTTTACCGTCGAACGATATCTGGTCATCACCAGGCCATTTCTTCGACAGAAATTGTCCCTTAATTCGCGTGTCTTCAAACTGGTCGGTGTTATATGGTTCGTGTCCTGCAGCTTTTGCATACCGGACCTCCTGTATATCGATATGATTGAAGAGAAGAAATATGTATTTTGCTATGTAGCAATGTCGCACATCGTGAGTGTATTTGTGGCAGCCGAGATCTTTGTTTTTTACGTGATACCAATGACGATTATTATAATATTGTACATATTAATAACAATAGAGTTAAAATTCAAAAAGAAACTTCGGAGCAGTCCCGCCAGCAATGGACAACAAAACAGAGATAAAGCGGTCATAATGTTAGCGGCTGTAGCTCTTTCGTTTTTTCTGTTCTGGTCACCATACTGTTACCTGCGCATCATGTTGATTTGGCCCGGTGTTTATGAGAAGCATTATAATGCATGGAAAATAGTGAATTATTTATGCTACAATTCGTACGCATCGAGCGCCTTAAACCCGATCCTATATAGTCTCATGTCACGGAAATTTCGACGTGCGTTCAAGGATTTTTTCACTAGACGAAAACCAGACAGTACCAATCGGAATGATATAGCCAAGGCTTCTTTGAGCAAAAATGAAACTAAATTGGAACTAAAGATGTAG

Protein

MMEPNNSEYENNSYITFFGPVGMAFYDNGQVLEDSLTVKIILSIILAVIMILSLIGNGCTCAVIARNRSMRTPTNCYLFNLAITDLFMALFVPIDIYIIWIPEFYPLGEVGCRLHFVLWDCLSNCSLLIITAFTVERYLVITRPFLRQKLSLNSRVFKLVGVIWFVSCSFCIPDLLYIDMIEEKKYVFCYVAMSHIVSVFVAAEIFVFYVIPMTIIIILYILITIELKFKKKLRSSPASNGQQNRDKAVIMLAAVALSFFLFWSPYCYLRIMLIWPGVYEKHYNAWKIVNYLCYNSYASSALNPILYSLMSRKFRRAFKDFFTRRKPDSTNRNDIAKASLSKNETKLELKM

Similarity

Belongs to the G-protein coupled receptor 1 family.

Uniprot

B3XXL4   A0A2A4J614   A0A2H1VTJ0   A0A0S1YD66   A0A194PNI7   A0A0S1YDX8   + More
A0A2A3EU95   C6YBD0   A0A0A1XIV8   A0A0M8ZWM1   A0A0S1YDK1   A0A1X9PPU6   A0A1I8NT01   A0A1I8NT05   Q7RTK3   B1Q298   Q29A18   A0A1I8N2I4   B0FYP0   R4LCH4   C9WBN0   A0A1I8N2F9   A0A1X9PPU5   B4G3L9   A0A3B0KPV7   Q27HC8   A0A0U1ZAZ7   C9WBN2   A0A1X9PQN0   H2CY19   A0A068FL22   Q9VFW5   C9WBN3   Q6WNX8   G5DFC3   B4HFU7   Q6VYH4   B3LX70   Q8ITD1   B4PPZ8   H2CY27   R4L363   B4R1B0   R4LB27   H2CY23   A0A0R3NGD2   A0A1W5K2U9   C9WBN1   A0A310SF16   B3P157   A0A1W4UJ26   A0A0R3NLE8   H2CY29   Q65YS4   A0A2A4JLW4   B4NKC2   A7YII1   H2CY28   A0A1B0G7K9   A0A0L7RBY5   F5HKX9   A0A182VN76   A7XII7   A0A0L0CE17   Q5ICC7   B1NPT7   H2CY20   A0A154P9V8   A0A1A9Y909   H2CY25   G3KFK9   A0A182Q2B0   A0A1A9VYF6   H2CY24   L7P6E7   A0A1B0AGN9   A0A1J1HQR4   A0A194PH11   A0A345ANM8   A0A3Q9NR23   A0A194R2M0   A7YII3   A0A1B6CAS5   B4KA85   E2BCE7   A0A182XVQ4   A0A212F409   A0A336LQE0   A0A195CMY0   A0A195DRH0   A0A195B9I0   A0A195FD90   A0A182YH30   I7DBT2   B4M6C3   I7DLN5   A0A336LAP1  

Pubmed

18725956    26354079    25830018    12951076    12364791    14747013    + More
17210077    15632085    17994087    25315136    20665850    23551811    17379458    22654850    26385554    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    23850474    12888624    12177421    17550304    15358772    18243415    17709098    26108605    17328713    20798317    25244985    22118469    22820129   

EMBL

AB330422    BAG68400.1    NWSH01003140    PCG66880.1    ODYU01004327    SOQ44076.1    + More
KT030999    ALM88297.1    KQ459603    KPI92685.1    KT031040    ALM88338.1    KZ288186    PBC34776.1    DQ869052    ABJ09599.1    GBXI01003346    JAD10946.1    KQ435847    KOX71113.1    KT031039    ALM88337.1    KX831609    ARO85771.1    BK001384    DAA01376.1    AAAB01008879    EAA08454.4    CM000070    EAL27533.1    EU365878    ABY62317.2    JX500423    AGL12068.1    FJ240221    ACQ90219.1    KX831611    ARO85773.1    CH479179    EDW25027.1    OUUW01000013    SPP87876.1    DQ407742    ABD52277.1    KM023791    AJW32184.1    FJ240223    ACQ90221.1    KX831610    ARO85772.1    JN228347    AEX15646.1    KJ622075    AID66638.1    AE014297    AAF54930.1    FJ240224    ACQ90222.1    AY277898    AAQ19543.1    JN648826    AEQ33641.1    CH480815    EDW42332.1    AY319852    AAP93921.1    CH902617    EDV41670.1    AF522189    AAN10042.1    CM000160    EDW97225.1    JN228355    AEX15648.1    JX500421    AGL12066.1    CM000364    EDX13087.1    JX500422    AGL12067.1    JN228351    AEX15647.1    KRT00094.1    KR069142    AMN09327.1    FJ240222    ACQ90220.1    KQ769179    OAD52895.1    CH954181    EDV49246.1    KRT00093.1    JN228357    AEX15642.1    JN228349    AB181298    AEX15640.1    BAD44726.1    NWSH01001040    PCG72971.1    CH964272    EDW84052.1    EU000525    ABU93812.1    JN228356    AEX15645.1    CCAG010018820    KQ414616    KOC68482.1    EGK96940.1    AY900219    AAX84798.1    JRES01000501    KNC30658.1    AY792036    AAW47417.1    EU000527    ABV58013.1    JN228348    AEX15643.1    KQ434839    KZC07970.1    JN228353    AEX15641.1    JN206677    AEO17028.2    AXCN02000293    JN228352    AEX15644.1    JQ255024    AFP19101.1    CVRI01000010    CRK88814.1    KPI92686.1    MF770988    AXF38050.1    MK288169    AZT88556.1    KQ460845    KPJ12038.1    EU000526    ABU93813.1    GEDC01026711    JAS10587.1    CH933806    EDW14572.1    GL447257    EFN86683.1    AGBW02010456    OWR48476.1    UFQT01000110    SSX20160.1    KQ977574    KYN01822.1    KQ980581    KYN15463.1    KQ976540    KYM81188.1    KQ981673    KYN38172.1    JQ686086    AFO73271.1    CH940652    EDW59199.1    JQ686085    AFO73270.1    UFQS01001440    UFQT01001440    SSX10908.1    SSX30586.1   

Proteomes

UP000218220    UP000053268    UP000242457    UP000005203    UP000053105    UP000095300    + More
UP000007062    UP000001819    UP000095301    UP000008744    UP000268350    UP000000803    UP000001292    UP000007801    UP000002282    UP000000304    UP000008711    UP000192221    UP000007798    UP000092444    UP000053825    UP000075903    UP000037069    UP000076502    UP000092443    UP000075886    UP000078200    UP000092445    UP000183832    UP000053240    UP000009192    UP000008237    UP000076408    UP000007151    UP000078542    UP000078492    UP000078540    UP000078541    UP000008792   

PRIDE

B3XXL4    H2CY19    Q9VFW5    Q6WNX8    Q8ITD1    Q65YS4    + More
H2CY20   

Pfam

PF00001   7tm_1        + More
PF15393   DUF4615

Interpro

IPR000276   GPCR_Rhodpsn        + More
IPR017452   GPCR_Rhodpsn_7TM       
IPR005390   NeuromedU_rcpt       
IPR029274   DUF4615       

ProteinModelPortal

B3XXL4   A0A2A4J614   A0A2H1VTJ0   A0A0S1YD66   A0A194PNI7   A0A0S1YDX8   + More
A0A2A3EU95   C6YBD0   A0A0A1XIV8   A0A0M8ZWM1   A0A0S1YDK1   A0A1X9PPU6   A0A1I8NT01   A0A1I8NT05   Q7RTK3   B1Q298   Q29A18   A0A1I8N2I4   B0FYP0   R4LCH4   C9WBN0   A0A1I8N2F9   A0A1X9PPU5   B4G3L9   A0A3B0KPV7   Q27HC8   A0A0U1ZAZ7   C9WBN2   A0A1X9PQN0   H2CY19   A0A068FL22   Q9VFW5   C9WBN3   Q6WNX8   G5DFC3   B4HFU7   Q6VYH4   B3LX70   Q8ITD1   B4PPZ8   H2CY27   R4L363   B4R1B0   R4LB27   H2CY23   A0A0R3NGD2   A0A1W5K2U9   C9WBN1   A0A310SF16   B3P157   A0A1W4UJ26   A0A0R3NLE8   H2CY29   Q65YS4   A0A2A4JLW4   B4NKC2   A7YII1   H2CY28   A0A1B0G7K9   A0A0L7RBY5   F5HKX9   A0A182VN76   A7XII7   A0A0L0CE17   Q5ICC7   B1NPT7   H2CY20   A0A154P9V8   A0A1A9Y909   H2CY25   G3KFK9   A0A182Q2B0   A0A1A9VYF6   H2CY24   L7P6E7   A0A1B0AGN9   A0A1J1HQR4   A0A194PH11   A0A345ANM8   A0A3Q9NR23   A0A194R2M0   A7YII3   A0A1B6CAS5   B4KA85   E2BCE7   A0A182XVQ4   A0A212F409   A0A336LQE0   A0A195CMY0   A0A195DRH0   A0A195B9I0   A0A195FD90   A0A182YH30   I7DBT2   B4M6C3   I7DLN5   A0A336LAP1  

PDB

4XEE     E-value=1.63376e-18,     Score=227

KEGG

100187558    K05052 neuromedin U receptor 1 | (RefSeq) NGR-A2, BNGR-A2; neuropeptide receptor A2

PATHWAY

04080    Neuroactive ligand-receptor interaction - Bombyx mori (domestic silkworm)

GO

GO:0007218   GO:0004930   GO:0016021   GO:0001607   GO:0036401   GO:0005887   GO:0007186   GO:0008188   GO:0016020   GO:0005852   GO:0006446   GO:0043022   GO:0005488   GO:0003707   GO:0051537  

Length:

351

Number of predicted TMHs:

7

Exp number of AAs in TMHs:

165.75372

Exp number, first 60 AAs:

28.2705

Total prob of N-in:

0.41235

POSSIBLE N-term signal

sequence

outside

1  -  35

TMhelix

36  -  58

inside

59  -  78

TMhelix

79  -  101

outside

102  -  115

TMhelix

116  -  135

inside

136  -  155

TMhelix

156  -  178

outside

179  -  199

TMhelix

200  -  222

inside

223  -  250

TMhelix

251  -  273

outside

274  -  287

TMhelix

288  -  310

inside

311  -  351

 

 

Pi

21.063343

Theta

21.777516

Tajima's D

0.254677

CLR

0.478666

CSRT

0.448427578621069

Interpretation

Uncertain