Gene

KWMTBOMO07356  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010679

Annotation

glutamyl_aminopeptidase-like_[Bombyx_mori]

Location

Bomo_Chr12(+):11082828-11104131      View in EpiBrowser

Full name

Aminopeptidase      

Location in the cell

PlasmaMembrane   Reliability : 1.569

CDS

ATGTCTCCGAAACTCTCACAATGCTTATTTAGAAACAACATCATCATTCTTCTAGGGCTTTTGTCGTTTTCCTTAATAGCCCCAGCAATTACGTTGACGACTTTTGACAAAAGGTCCAAAACATGTGAAAGCGATGACTGCGTGCCCATGGCTGTCAGAGAAGAAACGAATTTGTCAAACGTAACTGAGAATGCAAATTACTACAGACTGCCTAACAACATCCTCCCTAAAAACTATAATCTGACATTGAAGCCGAACATGAAAGATAATATTTTCAAAGGCACAGTCAACATTGCAATAGAAGTACTGACATCTACGAATAAAATCACCATGCATGCTTATAAGTTAACTATTGAATCCGTGATTTTGAAAGATTCGAAGAACGTGGAAGTCTCAATATCAAGTATAAACATAAGTACCGATAAAAGAGAATTGCTCAGAATACACTTAAATGATCAAATACAGAGGGGAAAATACAATGTGGAAATTGTATTCCAAGGAAACATGGATAAGAAAATAATTGGGTTTTACTCAAGTTCTTTGAAAAACGGAGGAACAATGGTAGCCAGTAAATTTCAGCCAACATATGCTCGCCAAGCATTCCCTTGTTTTGATGAGCCAGATTTCAAAGCCACATATGATATTGCACTTGTTAAACCCGAAGGGTATGTGGCATTGTCAAACATGAATGAAATATCAGTGACACGGGACCCATCATCTGATTTAGAAACTGTCAAATTTGCGACCAGTGTCCCAATGTCGACATATCTGGCTTGTTTTGTTGTATGTGATTTTGGATATAAGGATGTTGAAATTAATACTTCTGGTATCGGAAATACTTTCAAACTTAGATCTTTTGCTCAAAAAAATGAACTTCATAAGATTGATTTTGCTCAAGACATTGGGAAGAGAGCTACTGAATTTTACATAAGATATTATGAAGTAGAATTTCCCTTGCCAAAATTAGATATGATTGCAATACCTGACTACATTTCTGGAGCCACTGAGCACTGGGGTCTTATAACATACAGAGAAACATCATTTCTGGTTGATGAGGCTACTGCTTCTGTTAAAAATAAGATCAGTATTGCTAATACTATAGCTCATGAACTGGCTCACATGTGGTTTGGAAATTTAGTGACAATGAAATGGTGGGATGAAGTATGGCTAAATGAAGGTTTTGCTTCCTACATGCAAGTTAAATCATTGAATGCAATTGAACCATCGTGGGCCATGTTGGATCAATTCTTAACAAAAACTGTTCATCCTGTACTAGTGACTGATGCCAAACTTTCAAGTCATCCTATAGTACAAACTGTGTCTACACCCGATCAGATAACATCAATATTTGACACAATTTCTTACAATAAAGGCGCATCCATATTAAGAATGCTCGAGGGTTTCATTGGCGAAGAAAACTTCCGTCGTGGCGTTTCAGATTACCTCAAGAAGTTTCAGTACGGTAATACAGTGACTCAAGATTTACTATCCTGTCTTGAAGTTTACTTTAAACAGGAAAATCCTGATTTAAGCCTGACTCACATCATGGATACGTGGACACAACAAATGGGTTATCCACTACTCTACGTTGAACCGGGGAATGGAACAAACACATACGTTGTTACTCAAAAACGGTTTTTGCTCGATCCTGACGCAGAATACACGAACGATTCGAAGTTCAATTACCGTTGGTACGTGCCGATAACTTACAAGACAAATAAAGGAAATTGCGGCAGAGTTATTTGGTTCCCCGATACGGTAGAGAGCGTAACACTGAATCTCGATGACAATATCAGATGGCTGAAAATTAATAACAATCAAATTGGTTATTATAGAGTTCATTATGCCGATGAGATGTGGCAAAATCTTATACTAGAGTTAAACGCTAAATCGAAAGAGTTAACAATATCAGATCGAGCGCATTTATTGGATGACGCGTTTGCTCTCGCCGAAGCCGGCTCGTTGCCTTACAATATAGCGTTGGATCTCACAACGTATCTCACTGTGGAGGATGATGAAATACCTTGGACGACCGCCGTATCAATATTCGGAGGCTTAGCCAGAAGATTGCTGAACACACCAGCGTACGATGACCTTAAGAGCTATATCCATGGTCTAGTGAAACCTGTATACGAGAAACAAAGTTGGGAAAAGGTTAATATTGGAGTTATTGAAAGGCTACTTCGAGCAAGGATACTAACTCTAGCAACTCGTTACCAATTGCCAGACGCCGAAGATAAAGTAAGAAATTTGTTCTTGAGTTGGCTGAACGGTCACGGTACTCCCGATGCCGTTGTGATCGAACCAGATTTGCGGGACTTTGTTTATTATTATGGAATGAGATCGGCCACTCAGCAAGAATGGGATAAGTTGTGGGAGATCTATTTAAAAGAGACGGACGTTCTCGAAGCCACGAAAATTCGAAGCGCCCTATCGGCGTCTCGTGACGCGAACATCTTAAAAAGATACTTGGAGCTGTCTTGGGACGAAGCGAACATTCGGAGCCAGGATTACTTAAACGTTTTAGCGGACGTCAGCGACAACCCTACCGGCACCGGTCTGGTTTGGGACGACGTGAGGACGCGATGGCCCCAGCTAGTCGACCGATTCACGTTGAACAGCCGTTACTTGGGCGGCCTCATTACCAGCATCACGAAATCATTTAGCACACAGCAAAAACTAAACGAGATGGAAGCATTCTTCGCTCAATATCCAGAAGCTGGTGCTGGCGAGGCCTCAAGAAAACGTGCTCTAGAAACAGTTCACAACAACATCAAGTGGTCTCAGAAGCACCGAGCGTCTGTCGCAGCCTGGCTGGAGAAACGTCGTTCTTGA

Protein

MSPKLSQCLFRNNIIILLGLLSFSLIAPAITLTTFDKRSKTCESDDCVPMAVREETNLSNVTENANYYRLPNNILPKNYNLTLKPNMKDNIFKGTVNIAIEVLTSTNKITMHAYKLTIESVILKDSKNVEVSISSINISTDKRELLRIHLNDQIQRGKYNVEIVFQGNMDKKIIGFYSSSLKNGGTMVASKFQPTYARQAFPCFDEPDFKATYDIALVKPEGYVALSNMNEISVTRDPSSDLETVKFATSVPMSTYLACFVVCDFGYKDVEINTSGIGNTFKLRSFAQKNELHKIDFAQDIGKRATEFYIRYYEVEFPLPKLDMIAIPDYISGATEHWGLITYRETSFLVDEATASVKNKISIANTIAHELAHMWFGNLVTMKWWDEVWLNEGFASYMQVKSLNAIEPSWAMLDQFLTKTVHPVLVTDAKLSSHPIVQTVSTPDQITSIFDTISYNKGASILRMLEGFIGEENFRRGVSDYLKKFQYGNTVTQDLLSCLEVYFKQENPDLSLTHIMDTWTQQMGYPLLYVEPGNGTNTYVVTQKRFLLDPDAEYTNDSKFNYRWYVPITYKTNKGNCGRVIWFPDTVESVTLNLDDNIRWLKINNNQIGYYRVHYADEMWQNLILELNAKSKELTISDRAHLLDDAFALAEAGSLPYNIALDLTTYLTVEDDEIPWTTAVSIFGGLARRLLNTPAYDDLKSYIHGLVKPVYEKQSWEKVNIGVIERLLRARILTLATRYQLPDAEDKVRNLFLSWLNGHGTPDAVVIEPDLRDFVYYYGMRSATQQEWDKLWEIYLKETDVLEATKIRSALSASRDANILKRYLELSWDEANIRSQDYLNVLADVSDNPTGTGLVWDDVRTRWPQLVDRFTLNSRYLGGLITSITKSFSTQQKLNEMEAFFAQYPEAGAGEASRKRALETVHNNIKWSQKHRASVAAWLEKRRS

Cofactor

Zn(2+)

Similarity

Belongs to the peptidase M1 family.

Feature

chain  Aminopeptidase

Uniprot

I3VR80   H9JMC6   A0A194PNI2   A0A3S2LS36   A0A2A4JGY4   A0A286LPZ9   + More
A0A1L8EJF3   A0A1L8EJ79   A0A1L8EJH8   A0A1I8MDK7   A0A1I8PTD3   A0A1W4U7A0   W8AS98   A0A0L0CEH0   B3P162   A0A0K8V4C0   B4M6C7   B4JEL8   B4G3L4   A0A0Q9X6W1   A0A0A1WLH6   Q9VFX0   Q29A14   Q86NQ5   A0A0M3QXN4   A0A0K8TTQ5   B4HG90   A0A1I8PGY6   A0A3B0K3M7   A0A0A1WTT6   A0A336LYS0   A0A1I8MQF9   A0A2J7PNK0   T1PDR7   A0A0L0CE23   A0A1L8DP89   A0A1A9VKN8   A0A1I8MQG5   A0A1L8EJB5   A0A067REW1   A0A1L8EJ70   A0A034VI37   A0A1Y1KMG6   A0A0K8V2U8   A0A0A1WY54   A0A1Y1KJS9   A0A0K8UPF8   A0A034VBA9   A0A1A9Y906   A0A1A9VYF7   A0A1B0BGT8   U5EU90   E2C1U5   B4G3L5   A0A1I8P3V9   W8AYS9   A0A1Y1KMH6   A0A1I8P3R0   A0A1I8NG19   A0A1I8Q3H2   A0A1B0AGP0   A0A182K7Z1   A0A1B0G7K8   A0A034VKU0   Q8IHC5   A0A034VK36   B4HG89   A0A1W4WP24   Q9VFW9   A9UNG9   Q9VFW8   A0A0K8US39   B4R1B3   A0A0Q9WUY2   B3P161   A0A1W4WCU2   A0A1B6C9L0   F5HKY0   A0A182HIX8   A0A182P2X3   A0A182X8C3   A0A182G9S4   A0A3B0K5B1   A0A0P6IZ91   A0A182XVQ3   A0A182USH2   A0A1B6EQM6   A0A182JEQ2   A0A1B6FX35   A0A182TTF3   A0A023EY50   A0A1Q3EZL5   Q173A7   A0A0P6J4X5   J9K7S8   A0A2A3E257   A0A1L8E630  

EC Number

3.4.11.-

Pubmed

19121390    26354079    25315136    24495485    26108605    17994087    + More
25830018    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    15632085    26369729    24845553    25348373    28004739    20798317    12364791    14747013    17210077    26483478    26999592    25244985    24945155    17510324   

EMBL

JQ061151    AFK85025.1    BABH01033483    BABH01033484    KQ459603    KPI92680.1    + More
RSAL01000020    RVE52664.1    NWSH01001630    PCG70652.1    MF425656    ASU92548.1    GFDG01000011    JAV18788.1    GFDG01000009    JAV18790.1    GFDG01000010    JAV18789.1    GAMC01017598    JAB88957.1    JRES01000501    KNC30646.1    CH954181    EDV49251.1    GDHF01032702    GDHF01018595    JAI19612.1    JAI33719.1    CH940652    EDW59203.2    CH916369    EDV93149.1    CH479179    EDW25022.1    CH933806    KRG01076.1    GBXI01014942    JAC99349.1    AE014297    BT133114    AAF54925.2    AEY64282.1    CM000070    EAL27537.2    BT003783    AAO41464.1    CP012526    ALC46233.1    GDAI01000077    JAI17526.1    CH480815    EDW42338.1    OUUW01000013    SPP87883.1    GBXI01012226    JAD02066.1    UFQT01000315    SSX23132.1    NEVH01023953    PNF17923.1    KA646839    AFP61468.1    KNC30663.1    GFDF01005802    JAV08282.1    GFDG01000018    JAV18781.1    KK852680    KDR18594.1    GFDG01000019    JAV18780.1    GAKP01016801    GAKP01016800    GAKP01016798    JAC42154.1    GEZM01083993    JAV60865.1    GDHF01019399    JAI32915.1    GBXI01010989    JAD03303.1    GEZM01083994    GEZM01083991    JAV60868.1    GDHF01023725    JAI28589.1    GAKP01019168    JAC39784.1    JXJN01013993    GANO01002425    JAB57446.1    GL452008    EFN78057.1    EDW25023.1    GAMC01016533    GAMC01016532    JAB90023.1    GEZM01083987    JAV60875.1    CCAG010018818    CCAG010018819    CCAG010018820    GAKP01016799    JAC42153.1    BT001313    AAN71068.1    GAKP01016802    JAC42150.1    EDW42337.1    AAF54926.3    BT031333    ABY21746.1    AAF54927.2    GDHF01023154    JAI29160.1    CM000364    EDX13090.1    CH964272    KRF99951.1    EDV49250.1    GEDC01027157    JAS10141.1    AAAB01008879    EGK96941.1    APCN01002103    APCN01002104    JXUM01049783    JXUM01049784    JXUM01049785    KQ561620    KXJ77985.1    SPP87882.1    GDUN01000766    JAN95153.1    GECZ01029696    JAS40073.1    AXCP01008598    GECZ01015088    JAS54681.1    GAPW01000124    JAC13474.1    GFDL01014303    JAV20742.1    CH477428    EAT41121.1    GDUN01000765    JAN95154.1    ABLF02038188    KZ288431    PBC25823.1    GFDG01004631    JAV14168.1   

Proteomes

UP000005204    UP000053268    UP000283053    UP000218220    UP000095301    UP000095300    + More
UP000192221    UP000037069    UP000008711    UP000008792    UP000001070    UP000008744    UP000009192    UP000000803    UP000001819    UP000092553    UP000001292    UP000268350    UP000235965    UP000078200    UP000027135    UP000092443    UP000092460    UP000008237    UP000092445    UP000075881    UP000092444    UP000192223    UP000000304    UP000007798    UP000007062    UP000075840    UP000075885    UP000076407    UP000069940    UP000249989    UP000076408    UP000075903    UP000075880    UP000075902    UP000008820    UP000007819    UP000242457   

PRIDE

I3VR80    H9JMC6    Q9VFX0    Q86NQ5    Q8IHC5    Q9VFW9    + More
A9UNG9    Q9VFW8   

Pfam

PF11838   ERAP1_C        + More
PF01433   Peptidase_M1

Interpro

IPR034016   M1_APN-typ        + More
IPR001930   Peptidase_M1       
IPR024571   ERAP1-like_C_dom       
IPR014782   Peptidase_M1_dom       
IPR042097   Aminopeptidase_N-like_N       

Gene 3D

2.60.40.1730    

CDD

cd09601  M1_APN_2

ProteinModelPortal

I3VR80   H9JMC6   A0A194PNI2   A0A3S2LS36   A0A2A4JGY4   A0A286LPZ9   + More
A0A1L8EJF3   A0A1L8EJ79   A0A1L8EJH8   A0A1I8MDK7   A0A1I8PTD3   A0A1W4U7A0   W8AS98   A0A0L0CEH0   B3P162   A0A0K8V4C0   B4M6C7   B4JEL8   B4G3L4   A0A0Q9X6W1   A0A0A1WLH6   Q9VFX0   Q29A14   Q86NQ5   A0A0M3QXN4   A0A0K8TTQ5   B4HG90   A0A1I8PGY6   A0A3B0K3M7   A0A0A1WTT6   A0A336LYS0   A0A1I8MQF9   A0A2J7PNK0   T1PDR7   A0A0L0CE23   A0A1L8DP89   A0A1A9VKN8   A0A1I8MQG5   A0A1L8EJB5   A0A067REW1   A0A1L8EJ70   A0A034VI37   A0A1Y1KMG6   A0A0K8V2U8   A0A0A1WY54   A0A1Y1KJS9   A0A0K8UPF8   A0A034VBA9   A0A1A9Y906   A0A1A9VYF7   A0A1B0BGT8   U5EU90   E2C1U5   B4G3L5   A0A1I8P3V9   W8AYS9   A0A1Y1KMH6   A0A1I8P3R0   A0A1I8NG19   A0A1I8Q3H2   A0A1B0AGP0   A0A182K7Z1   A0A1B0G7K8   A0A034VKU0   Q8IHC5   A0A034VK36   B4HG89   A0A1W4WP24   Q9VFW9   A9UNG9   Q9VFW8   A0A0K8US39   B4R1B3   A0A0Q9WUY2   B3P161   A0A1W4WCU2   A0A1B6C9L0   F5HKY0   A0A182HIX8   A0A182P2X3   A0A182X8C3   A0A182G9S4   A0A3B0K5B1   A0A0P6IZ91   A0A182XVQ3   A0A182USH2   A0A1B6EQM6   A0A182JEQ2   A0A1B6FX35   A0A182TTF3   A0A023EY50   A0A1Q3EZL5   Q173A7   A0A0P6J4X5   J9K7S8   A0A2A3E257   A0A1L8E630  

PDB

4KXD     E-value=5.63718e-158,     Score=1434

KEGG

101744117    K11141 glutamyl aminopeptidase [EC:3.4.11.7] | (RefSeq) glutamyl aminopeptidase-like

GO

GO:0008270   GO:0002003   GO:0070006   GO:0008237   GO:0004177   GO:0016021   GO:0033227   GO:0005737   GO:0043171   GO:0042277   GO:0006508   GO:0001607   GO:0005852   GO:0006446   GO:0043022   GO:0005488   GO:0003707   GO:0051537  

SignalP

Position:   1 - 29,         Likelihood:  0.766682

 

 

Length:

944

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

21.9171999999999

Exp number, first 60 AAs:

21.9081

Total prob of N-in:

0.99571

POSSIBLE N-term signal

sequence

inside

1  -  12

TMhelix

13  -  35

outside

36  -  944

 

 

Pi

20.5103

Theta

19.856299

Tajima's D

0.249694

CLR

0.824573

CSRT

0.456627168641568

Interpretation

Uncertain