Gene

KWMTBOMO07329  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010620

Annotation

syntaxin_5A_[Bombyx_mori]

Location

Bomo_Chr12(-):10678162-10682341      View in EpiBrowser

Full name

Syntaxin-5      

Alternative Name

Sed5 protein
dSed5

Location in the cell

Mitochondrial   Reliability : 1.395 Nuclear   Reliability : 2.066

CDS

ATGCTTCCTCGAAGGCGAAATATAGGCGTTACAGAAAGACTCTTGGAAACAGAAACGGATTCATACAATAAATTAGATAAGAAAGAAGAATTTGTTTTTGAACCAGTTATGGCTTCAAGAGATAGAACAAGTGAATTCATTTCAACTGTACGCAGTCTCCAAGGACGTTTCTTAAACAAACCAACCGTAAGAGATGATAGAAAAGCTGCTGTGTTGGAAACTTACTCCCAATTCATGAGTATGGCAAAAGTAATTAGTAAGAATATTACTAGTACATATACCAAATTGGAAAAGTTAGCCTTGTTGGCTAAGAGGAAATCATTATTTGATGACCGTCCCACAGAAATTCAAGAACTAACTTATATTATTAAAGGAGACTTAAATTCTTTAAATCAACAAATTGCCAGACTAGGTGAAATGCCAAGAGGTCGTCGCAGTATGCACAGTCATTCATCTAGTGTTGTACTCGCATTACAGTCACGCCTTGCTTCAATGAGTAATCAATTTAAACAGGTCTTAGAAGTTCGTTCAGAAAATTTGAAGCAACAGAACAGCAGGCGTGAACAATTTTCAAGGGTGACACCGGTTGTAAAAGAGGTACCATCTCTATTGCAACAAGATGAAGTAAGCATAGATTTGGGTGAAGCTACAAGTTTACAAGCACAGCAATTTGCATTCAGAGATGATACAGACTCATATGTACAACAGAGAGCTGAAACTATGCATAACATTGAAAGCACTATTGTGGAGTTGGGAGGCATATTTCAACAATTGGCTCATATGGTAAAAGAACAAGATGAAGCTATTGGTAGAATTGATGCAAACATTCATGAGGCAGAAATGAATGTTGAAGCTGGCCACAGAGAAATATTGAAATATTTCCAAAATGTAACTGGAAATAGGGCGTTAATGTTTAAAGTTTTTGGGGTTTTAATATTCTTTTTCATATTTTTTGTGGTGTTTATGGCTTAA

Protein

MLPRRRNIGVTERLLETETDSYNKLDKKEEFVFEPVMASRDRTSEFISTVRSLQGRFLNKPTVRDDRKAAVLETYSQFMSMAKVISKNITSTYTKLEKLALLAKRKSLFDDRPTEIQELTYIIKGDLNSLNQQIARLGEMPRGRRSMHSHSSSVVLALQSRLASMSNQFKQVLEVRSENLKQQNSRREQFSRVTPVVKEVPSLLQQDEVSIDLGEATSLQAQQFAFRDDTDSYVQQRAETMHNIESTIVELGGIFQQLAHMVKEQDEAIGRIDANIHEAEMNVEAGHREILKYFQNVTGNRALMFKVFGVLIFFFIFFVVFMA

Description

Mediates endoplasmic reticulum to Golgi transport.

Subunit

Homodimer.

Similarity

Belongs to the syntaxin family.
Belongs to the cullin family.

Keywords

Coiled coil   Complete proteome   ER-Golgi transport   Golgi apparatus   Membrane   Reference proteome   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Syntaxin-5

Uniprot

H9JM67   Q1HQ40   A0A3S2LPV2   A0A2H1VE62   A0A194PGY4   A0A2A4J0R1   + More
A0A0N1IET6   A0A1E1WLZ8   A0A0L7LJC8   A0A212EU01   S4PGC9   A0A1J1IJJ4   A0A0K8TPE5   A0A2M3Z5E0   A0A2M3Z5E2   A0A2M4A977   A0A1W4X1W2   B4NXP5   A0A1W4VXZ9   W5JQT0   A0A2M4BNY1   A0A2M4BNJ5   A0A182F1I6   A0A0J9R2N6   A4V0S1   Q24509   B4I216   B4KI21   B3N660   A0A2J7PMX0   A0A2P8YVI3   B3MJN9   A0A3B0JGJ7   B0W6Z0   A0A0L0CC41   A0A067RN12   A0A182RVR5   A0A1I8MP04   A0A182VTK4   A0A1I8Q4F3   U5ERI5   A0A182P2U7   A0A1B0C025   A0A1A9Y5B6   A0A182NB86   B4GQN1   Q29NM4   A0A182SPP9   A0A1A9WM30   B4MU60   A0A182JII3   A0A1B6BXF3   A0A182QTU8   A0A1Y1K3U5   A0A1L8DVD0   A0A084VMP3   A0A182YM18   A0A182M109   A0A1B0A3Y4   A0A034W3F3   B4LTD5   A0A0K8VXJ5   A0A0A1WT30   B4Q700   A0A182UGM7   A0A0M4EGE1   A0A182KWL5   A0A182K7M8   A0A1A9UR06   A0A182VCS8   W8BWL3   A0A182G2K4   D3TPX4   V5IA44   A0A182IB78   A0A182X656   A0A1S4GZ62   B4JAB8   A0A0T6AYM1   J3JWV9   A0A336KM01   A0A0K8STS9   A0A146L5A7   A0A0C9RJL3   A0A182GUF8   A0A0L7RJC8   T1JGD8   E0VP35   A0A0V0G2X3   A0A069DSZ1   A0A224XT20   A0A2C9KBG1   T1I8W4   A0A0P4VL18   E2AXV7   U4UDG3   A0A026WM58   A0A154P0D0   M7BCC2   A0A0B7ATL4  

Pubmed

19121390    26354079    26227816    22118469    23622113    26369729    + More
17994087    17550304    20920257    23761445    22936249    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    10471707    12537569    7929581    29403074    18057021    26108605    24845553    25315136    15632085    28004739    24438588    25244985    25348373    25830018    20966253    24495485    26483478    20353571    12364791    22516182    26823975    20566863    26334808    15562597    27129103    20798317    23537049    24508170    30249741    23624526   

EMBL

BABH01033436    BABH01033437    DQ443212    ABF51301.1    RSAL01000762    RVE41167.1    + More
ODYU01002047    SOQ39066.1    KQ459603    KPI92656.1    NWSH01004441    PCG65114.1    KQ460456    KPJ14661.1    GDQN01003001    JAT88053.1    JTDY01000955    KOB75296.1    AGBW02012509    OWR44970.1    GAIX01003712    JAA88848.1    CVRI01000054    CRL00415.1    GDAI01001580    JAI16023.1    GGFM01002981    MBW23732.1    GGFM01002982    MBW23733.1    GGFK01004032    MBW37353.1    CM000157    EDW89670.1    KRJ98651.1    ADMH02000444    ETN66456.1    GGFJ01005510    MBW54651.1    GGFJ01005509    MBW54650.1    CM002910    KMY90496.1    KMY90497.1    AE014134    AAN10935.1    AY069832    X78219    AAF53520.2    AAL39977.1    CAA55064.1    CH480820    EDW54573.1    CH933807    EDW11303.1    CH954177    EDV58098.1    NEVH01023960    PNF17684.1    PYGN01000337    PSN48254.1    CH902620    EDV31378.1    KPU73342.1    KPU73343.1    OUUW01000006    SPP81477.1    DS231851    EDS37264.1    JRES01000714    KNC29009.1    KK852572    KDR21104.1    GANO01003727    JAB56144.1    JXJN01023462    CH479187    EDW39903.1    CH379059    EAL34194.1    CH963852    EDW75649.2    GEDC01031663    GEDC01001151    JAS05635.1    JAS36147.1    AXCN02000633    GEZM01093798    JAV56122.1    GFDF01003686    JAV10398.1    ATLV01014616    KE524975    KFB39237.1    AXCM01000488    GAKP01010659    JAC48293.1    CH940649    EDW63905.1    GDHF01009069    JAI43245.1    GBXI01012632    JAD01660.1    CM000361    EDX05208.1    CP012523    ALC39755.1    GAMC01005262    JAC01294.1    JXUM01139644    JXUM01139645    JXUM01139646    JXUM01139647    JXUM01139648    KQ568932    KXJ68833.1    CCAG010009633    EZ423476    ADD19752.1    GALX01001830    JAB66636.1    APCN01000644    AAAB01008944    CH916368    EDW03789.1    LJIG01022493    KRT80287.1    BT127727    AEE62689.1    UFQS01000439    UFQT01000439    SSX03953.1    SSX24318.1    GBRD01009544    JAG56280.1    GDHC01015026    GDHC01007955    JAQ03603.1    JAQ10674.1    GBYB01007061    GBYB01011406    JAG76828.1    JAG81173.1    JXUM01089073    JXUM01089074    JXUM01089075    JXUM01089076    JXUM01089077    KQ563744    KXJ73397.1    KQ414579    KOC71077.1    JH432201    DS235354    EEB15141.1    GECL01003626    JAP02498.1    GBGD01002107    JAC86782.1    GFTR01005163    JAW11263.1    ACPB03001979    ACPB03001980    GDKW01003549    JAI53046.1    GL443736    EFN61721.1    KB632308    ERL92014.1    KK107168    QOIP01000001    EZA56189.1    RLU27429.1    KQ434782    KZC04600.1    KB586437    EMP25857.1    HACG01037057    HACG01037060    CEK83922.1    CEK83925.1   

Proteomes

UP000005204    UP000283053    UP000053268    UP000218220    UP000053240    UP000037510    + More
UP000007151    UP000183832    UP000192223    UP000002282    UP000192221    UP000000673    UP000069272    UP000000803    UP000001292    UP000009192    UP000008711    UP000235965    UP000245037    UP000007801    UP000268350    UP000002320    UP000037069    UP000027135    UP000075900    UP000095301    UP000075920    UP000095300    UP000075885    UP000092460    UP000092443    UP000075884    UP000008744    UP000001819    UP000075901    UP000091820    UP000007798    UP000075880    UP000075886    UP000030765    UP000076408    UP000075883    UP000092445    UP000008792    UP000000304    UP000075902    UP000092553    UP000075882    UP000075881    UP000078200    UP000075903    UP000069940    UP000249989    UP000092444    UP000075840    UP000076407    UP000001070    UP000053825    UP000009046    UP000076420    UP000015103    UP000000311    UP000030742    UP000053097    UP000279307    UP000076502    UP000031443   

PRIDE

H9JM67    Q1HQ40    A4V0S1    Q24509   

Pfam

PF11416   Syntaxin-5_N        + More
PF05739   SNARE
PF00804   Syntaxin
PF01846   FF
PF00397   WW
PF10557   Cullin_Nedd8
PF00888   Cullin

Interpro

IPR010989   SNARE        + More
IPR006011   Syntaxin_N       
IPR000727   T_SNARE_dom       
IPR021538   Syntaxin-5_N       
IPR039726   Prp40-like       
IPR036020   WW_dom_sf       
IPR001202   WW_dom       
IPR002713   FF_domain       
IPR036517   FF_domain_sf       
IPR006012   Syntaxin/epimorphin_CS       
IPR016159   Cullin_repeat-like_dom_sf       
IPR016158   Cullin_homology       
IPR036317   Cullin_homology_sf       
IPR019559   Cullin_neddylation_domain       
IPR036390   WH_DNA-bd_sf       
IPR001373   Cullin_N       
IPR036388   WH-like_DNA-bd_sf       

SUPFAM

SSF47661   SSF47661        + More
SSF51045   SSF51045       
SSF81698   SSF81698       
SSF75632   SSF75632       
SSF74788   SSF74788       
SSF46785   SSF46785       

Gene 3D

1.10.10.440     1.10.10.10    

CDD

cd00201  WW

ProteinModelPortal

H9JM67   Q1HQ40   A0A3S2LPV2   A0A2H1VE62   A0A194PGY4   A0A2A4J0R1   + More
A0A0N1IET6   A0A1E1WLZ8   A0A0L7LJC8   A0A212EU01   S4PGC9   A0A1J1IJJ4   A0A0K8TPE5   A0A2M3Z5E0   A0A2M3Z5E2   A0A2M4A977   A0A1W4X1W2   B4NXP5   A0A1W4VXZ9   W5JQT0   A0A2M4BNY1   A0A2M4BNJ5   A0A182F1I6   A0A0J9R2N6   A4V0S1   Q24509   B4I216   B4KI21   B3N660   A0A2J7PMX0   A0A2P8YVI3   B3MJN9   A0A3B0JGJ7   B0W6Z0   A0A0L0CC41   A0A067RN12   A0A182RVR5   A0A1I8MP04   A0A182VTK4   A0A1I8Q4F3   U5ERI5   A0A182P2U7   A0A1B0C025   A0A1A9Y5B6   A0A182NB86   B4GQN1   Q29NM4   A0A182SPP9   A0A1A9WM30   B4MU60   A0A182JII3   A0A1B6BXF3   A0A182QTU8   A0A1Y1K3U5   A0A1L8DVD0   A0A084VMP3   A0A182YM18   A0A182M109   A0A1B0A3Y4   A0A034W3F3   B4LTD5   A0A0K8VXJ5   A0A0A1WT30   B4Q700   A0A182UGM7   A0A0M4EGE1   A0A182KWL5   A0A182K7M8   A0A1A9UR06   A0A182VCS8   W8BWL3   A0A182G2K4   D3TPX4   V5IA44   A0A182IB78   A0A182X656   A0A1S4GZ62   B4JAB8   A0A0T6AYM1   J3JWV9   A0A336KM01   A0A0K8STS9   A0A146L5A7   A0A0C9RJL3   A0A182GUF8   A0A0L7RJC8   T1JGD8   E0VP35   A0A0V0G2X3   A0A069DSZ1   A0A224XT20   A0A2C9KBG1   T1I8W4   A0A0P4VL18   E2AXV7   U4UDG3   A0A026WM58   A0A154P0D0   M7BCC2   A0A0B7ATL4  

PDB

1GL2     E-value=0.021736,     Score=88

KEGG

732925    K08490 syntaxin 5 | (RefSeq) syntaxin 5A

PATHWAY

04130    SNARE interactions in vesicular transport - Bombyx mori (domestic silkworm)

GO

GO:0016192   GO:0016021   GO:0045292   GO:0016020   GO:0006886   GO:0005623   GO:0005484   GO:0000902   GO:0007283   GO:0060305   GO:0035167   GO:0042803   GO:0000281   GO:0007112   GO:0008283   GO:0007030   GO:0009306   GO:0006887   GO:0005801   GO:0006878   GO:0045930   GO:0016081   GO:0012505   GO:0007269   GO:0000149   GO:0000139   GO:0005794   GO:0005886   GO:0055070   GO:0098793   GO:0005783   GO:0031201   GO:0006511   GO:0031625   GO:0005515   GO:0006487   GO:0006488   GO:0007156   GO:0008237   GO:0043401   GO:0003707   GO:0051537  

PANTHER

PTHR11864  

Subcellular location

  

Length:

323

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

20.38709

Exp number, first 60 AAs:

0

Total prob of N-in:

0.60513

inside

1  -  301

TMhelix

302  -  321

outside

322  -  323

 

 

Pi

0.420184

Theta

1.925899

Tajima's D

-1.492888

CLR

1089.441074

CSRT

0.0495975201239938

Interpretation

Possibly Positive selection