Description
Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging (By similarity).
Subunit
Homodimer. Binds non-specifically to double-stranded DNA, and is found as hexamer or dodecamer upon DNA binding. Binds to LEM domain-containing nuclear proteins (By similarity). Interacts with nemp1a and nemp1b.
Subcellular location
Nucleus
Colocalizes with nemp1a and nemp1b at the nuclear envelope. With evidence from 2 publications.
Nucleus envelope
Colocalizes with nemp1a and nemp1b at the nuclear envelope. With evidence from 2 publications.
Chromosome
Colocalizes with nemp1a and nemp1b at the nuclear envelope. With evidence from 2 publications.