Gene

KWMTBOMO07323  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010666

Annotation

chaperonin_subunit_4_delta_[Bombyx_mori]

Location

Bomo_Chr12(+):10629842-10637650      View in EpiBrowser

Full name

T-complex protein 1 subunit delta      

Alternative Name

CCT-delta

Location in the cell

Cytoplasmic   Reliability : 2.65

CDS

ATGGCTCCGAAAGCTGGCGGTGATGCTATTAAAGCTAATTCTTCAGTATATAAAGATAAAAGTAAACCTACAGACATCAGACTGAGCAACATAAATGCCGCAAAAGCTGTTGCTGATGCCATCCGCACAAGCTTAGGGCCTCGTGGAATGGATAAGATGATTCAAGCAGCCAATGGAGAAGTTACAATAACTAATGATGGAGCAACAATTTTGAAACAAATGAGTGTTATTCATCCAGCTGCAAAAATGTTGGTAGAATTATCTCGTGCTCAAGATATTGAAGCTGGTGATGGAACAACATCAGTAGTTGTTATTGCTGGTGCGTTGTTGGATTCTGCTGAGAAACTTCTTCAGAAAGGCATACATCCAACTGTAATTTCTGATGGTTTCCAAAAAGCCCTTCAATTGGCTTTACAGGTGGTCGAAAATATGTCAACTCCAGTGGACTTGAATAATGAAGATGCTTTGCTCAAGGCAGCTGCAACATCACTAAATTCCAAAGTAGTTTCACAACACTCAACTATTTTGGCACCCATTGCAGTGCAAGCAATTCGAGCAGTAATGGAACCTATTGTTAGTGGTGTTGGTGCAAGAGTTGACCTCAGAGATGTGAAAGTCATTGAGCGTATAGGTGGAACTGTAGAAGATGCTGAGCTAATCCAAGGATTGGTCATTCCGCATCGTGCAGCCAATGTGAATGGCCCTCATCGCATTGAAAAGGCTAAAGTTGGTCTTATACAATTTTGCATTTCGCCTCCCAAAACTGATATGGACCACAATGTTATTGTATCAGATTATGCAGCAATGGATCGTGTGTTGAAGGAAGAACGCCAATATATTTTGAATATTGTAAAACAGATCAAAAAAGCTGGTTGTAATGTACTTTTAGTTCAAAAATCTATATTAAGAGATGCCCTGAGTGACTTGGCTGTACATTTCTTAGACAAAATTAAAACAATGGTCATTAAAGATATTGAACGTGAAGACATTGAATTTGTTTGCAAAACCTTAGGATGCAGGCCAATTGCTTCTTTGGATCATTTTACAGCTGAAAATTTAGTCAATGTTGATTTGGTTGAAGAAATAAATGAACCTGGTGGAAAATATATAAAGATGACGGGTTGCGGTCAGGGCGGTCGCACAGTGAGCGTATTGGTTCGCGGATCGAGTGGCGCCGTGGTGGCAGAGGCAGCGCGATCTCTTCACGACGCCTTATGTGCCGTGCGCTGTGTGGCGCGCCGCCCTGCATTGTTGGCCGGCGGCGGCGCTCCCGAGGCTGCAGCGGCGGCCAGTCTCGCGCGTGCTTCTCTCGCAGCACCCGGAGCCGATCACTATTGTCTACGTGCCTACGCCGATGCTCTCGAAGTCATACCCTCCACGCTTGCCGAGAATGCAGGTTTGAACCCAATTGAGACCGTAACTGAGCTACGAGCCGCTCACGCTGCTGGCGCTGGCGGTGGCGCCGGTGTCAACGTACGCCGCGGACGAGTTACAGATATGCGCACGGAGCATGTGCTGCAACCGCTTCATGTTACAGCTTCCGCGCTCGCACTCGCAACCGAAACTGTGCGTGCTATACTCAAAATTGATGACATTATAAATACAATGAATTAG

Protein

MAPKAGGDAIKANSSVYKDKSKPTDIRLSNINAAKAVADAIRTSLGPRGMDKMIQAANGEVTITNDGATILKQMSVIHPAAKMLVELSRAQDIEAGDGTTSVVVIAGALLDSAEKLLQKGIHPTVISDGFQKALQLALQVVENMSTPVDLNNEDALLKAAATSLNSKVVSQHSTILAPIAVQAIRAVMEPIVSGVGARVDLRDVKVIERIGGTVEDAELIQGLVIPHRAANVNGPHRIEKAKVGLIQFCISPPKTDMDHNVIVSDYAAMDRVLKEERQYILNIVKQIKKAGCNVLLVQKSILRDALSDLAVHFLDKIKTMVIKDIEREDIEFVCKTLGCRPIASLDHFTAENLVNVDLVEEINEPGGKYIKMTGCGQGGRTVSVLVRGSSGAVVAEAARSLHDALCAVRCVARRPALLAGGGAPEAAAAASLARASLAAPGADHYCLRAYADALEVIPSTLAENAGLNPIETVTELRAAHAAGAGGGAGVNVRRGRVTDMRTEHVLQPLHVTASALALATETVRAILKIDDIINTMN

Description

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

Subunit

Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

Similarity

Belongs to the TCP-1 chaperonin family.

Keywords

ATP-binding   Chaperone   Cytoplasm   Nucleotide-binding  

Feature

chain  T-complex protein 1 subunit delta

Uniprot

Q2F6C4   H9JMB3   A0A2H1V5C0   A0A212ETZ6   S4PHL1   A0A194PH72   + More
A0A194R301   A0A2A4IYU0   B4MDL7   A0A1Y1M3T7   B4MWN7   B4KIN7   V5G4G3   B3MNJ7   B4JCN1   A0A3B0JML9   A0A0K8UHH1   K7ILV5   Q29L81   W8APG2   A0A034WRN7   A0A0C9QQQ2   B4HB36   D2A1X9   A0A0L0CII4   A0A1I8MLK1   A0A0N0BKX4   A0A1B6LZ41   T1PFX8   Q9VK69   A0A1B6EX07   A0A182LWT3   A0A1A9WUI1   B4P2H9   A0A2A3E687   V9IHB3   A0A088AHM7   A0A0J9R146   A0A0M4E5N0   B3N3D6   A0A1B6DNB6   A0A182VUY3   A0A1W4V5I8   A0A097P6J3   A0A1I8NV30   B4IEB2   W5J975   A0A154P1G3   A0A2M4A9F9   A0A310SHQ9   A0A084VPG9   A0A182S4R7   A0A2M4BJP8   A0A2M4BK72   A0A182PD84   A0A026W822   A0A1L8ECW3   A0A2M3Z334   A0A182F559   A0A232FL45   E9IGN8   A0A0M4E1N5   Q171B7   A0A182JIF7   E2AX57   A0A182TXH4   A0A182X7L7   Q7QG50   A0A182IE50   A0A182QCT9   A0A1Q3F3R6   A0A182K0N8   E2B8Q4   A0A151X3S1   A0A182VJ93   A0A182Y5V1   A0A1L8DUD3   A0A1L8DUB8   Q9NB32   A0A195EEX5   A0A0J7L083   A0A1W4X1L7   A0A195ESL8   F4WQT6   A0A182GEL1   A0A1S3D225   A0A023EWC4   A0A067RDC2   A0A158NRS2   A0A023ETP0   W5U591   B0W5S5   A0A336KPC9   A0A0K8TST0   A0A195BRM7   U5EX42   A0A195D142   A0A224XN34   A0A0A9Y6Y1   J9JSI4  

Pubmed

19121390    22118469    23622113    26354079    17994087    28004739    + More
20075255    15632085    24495485    25348373    18362917    19820115    26108605    25315136    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    17550304    22936249    20920257    23761445    24438588    24508170    30249741    28648823    21282665    17510324    20798317    12364791    14747013    17210077    25244985    11762197    21719571    26483478    24945155    24845553    21347285    26369729    25401762    26823975   

EMBL

DQ311148    ABD36093.1    BABH01033429    BABH01033430    ODYU01000758    SOQ36027.1    + More
AGBW02012509    OWR44966.1    GAIX01003232    JAA89328.1    KQ459603    KPI92652.1    KQ460845    KPJ12067.1    NWSH01004441    PCG65107.1    CH940661    EDW71278.1    GEZM01045202    JAV77867.1    CH963857    EDW76526.1    CH933807    EDW11380.1    GALX01003551    JAB64915.1    CH902620    EDV32105.1    CH916368    EDW04195.1    OUUW01000006    SPP82103.1    GDHF01026177    JAI26137.1    CH379061    EAL32943.1    GAMC01020147    JAB86408.1    GAKP01001658    JAC57294.1    GBYB01002992    JAG72759.1    CH479247    EDW37839.1    KQ971338    EFA02141.1    JRES01000438    KNC31299.1    KQ435689    KOX81218.1    GEBQ01011020    JAT28957.1    KA647661    AFP62290.1    AE014134    AY128484    AAF53210.1    AAM75077.1    GECZ01027270    GECZ01026922    JAS42499.1    JAS42847.1    AXCM01006443    CM000157    EDW88209.1    KZ288371    PBC26736.1    JR042985    AEY59704.1    CM002910    KMY89947.1    CP012523    ALC39446.1    CH954177    EDV58776.1    GEDC01010133    JAS27165.1    KM215142    AIU39615.1    CH480831    EDW45939.1    ADMH02002089    ETN59400.1    KQ434796    KZC05662.1    GGFK01004088    MBW37409.1    KQ768478    OAD53120.1    ATLV01015004    KE524999    KFB39863.1    GGFJ01004158    MBW53299.1    GGFJ01004263    MBW53404.1    KK107347    QOIP01000007    EZA52257.1    RLU21000.1    GFDG01002380    JAV16419.1    GGFM01002152    MBW22903.1    NNAY01000091    OXU31067.1    GL763054    EFZ20189.1    ALC39328.1    CH477460    EAT40572.1    GL443520    EFN62007.1    AAAB01008839    EAA05907.2    APCN01004564    AXCN02000859    GFDL01012868    JAV22177.1    GL446361    EFN87960.1    KQ982562    KYQ54920.1    GFDF01004045    JAV10039.1    GFDF01004046    JAV10038.1    AF271209    KQ978983    KYN26825.1    LBMM01001595    KMQ96041.1    KQ981993    KYN30907.1    GL888275    EGI63449.1    JXUM01058230    JXUM01058231    JXUM01058232    KQ561993    KXJ76960.1    GAPW01000894    JAC12704.1    KK852777    KDR16778.1    ADTU01024286    GAPW01000895    JAC12703.1    KF813101    AHH35014.1    DS231844    EDS35728.1    UFQS01000672    UFQT01000055    UFQT01000672    SSX06011.1    SSX19079.1    GDAI01000415    JAI17188.1    KQ976424    KYM88596.1    GANO01001132    JAB58739.1    KQ977041    KYN06124.1    GFTR01006995    JAW09431.1    GBHO01016761    GBRD01010602    GDHC01007949    JAG26843.1    JAG55222.1    JAQ10680.1    ABLF02036421   

Proteomes

UP000005204    UP000007151    UP000053268    UP000053240    UP000218220    UP000008792    + More
UP000007798    UP000009192    UP000007801    UP000001070    UP000268350    UP000002358    UP000001819    UP000008744    UP000007266    UP000037069    UP000095301    UP000053105    UP000000803    UP000075883    UP000091820    UP000002282    UP000242457    UP000005203    UP000092553    UP000008711    UP000075920    UP000192221    UP000095300    UP000001292    UP000000673    UP000076502    UP000030765    UP000075900    UP000075885    UP000053097    UP000279307    UP000069272    UP000215335    UP000008820    UP000075880    UP000000311    UP000075902    UP000076407    UP000007062    UP000075840    UP000075886    UP000075881    UP000008237    UP000075809    UP000075903    UP000076408    UP000078492    UP000036403    UP000192223    UP000078541    UP000007755    UP000069940    UP000249989    UP000079169    UP000027135    UP000005205    UP000002320    UP000078540    UP000078542    UP000007819   

PRIDE

Q2F6C4    H9JMB3    Q9VK69    A0A088AHM7    Q9NB32   

Pfam

PF00118   Cpn60_TCP1

Interpro

IPR027410   TCP-1-like_intermed_sf        + More
IPR012717   Chap_CCT_delta       
IPR002423   Cpn60/TCP-1       
IPR017998   Chaperone_TCP-1       
IPR002194   Chaperonin_TCP-1_CS       
IPR027413   GROEL-like_equatorial_sf       
IPR027409   GroEL-like_apical_dom_sf       

SUPFAM

SSF52029   SSF52029        + More
SSF54849   SSF54849       
SSF48592   SSF48592       

Gene 3D

1.10.560.10     3.50.7.10     3.30.260.10    

CDD

cd03338  TCP1_delta

ProteinModelPortal

Q2F6C4   H9JMB3   A0A2H1V5C0   A0A212ETZ6   S4PHL1   A0A194PH72   + More
A0A194R301   A0A2A4IYU0   B4MDL7   A0A1Y1M3T7   B4MWN7   B4KIN7   V5G4G3   B3MNJ7   B4JCN1   A0A3B0JML9   A0A0K8UHH1   K7ILV5   Q29L81   W8APG2   A0A034WRN7   A0A0C9QQQ2   B4HB36   D2A1X9   A0A0L0CII4   A0A1I8MLK1   A0A0N0BKX4   A0A1B6LZ41   T1PFX8   Q9VK69   A0A1B6EX07   A0A182LWT3   A0A1A9WUI1   B4P2H9   A0A2A3E687   V9IHB3   A0A088AHM7   A0A0J9R146   A0A0M4E5N0   B3N3D6   A0A1B6DNB6   A0A182VUY3   A0A1W4V5I8   A0A097P6J3   A0A1I8NV30   B4IEB2   W5J975   A0A154P1G3   A0A2M4A9F9   A0A310SHQ9   A0A084VPG9   A0A182S4R7   A0A2M4BJP8   A0A2M4BK72   A0A182PD84   A0A026W822   A0A1L8ECW3   A0A2M3Z334   A0A182F559   A0A232FL45   E9IGN8   A0A0M4E1N5   Q171B7   A0A182JIF7   E2AX57   A0A182TXH4   A0A182X7L7   Q7QG50   A0A182IE50   A0A182QCT9   A0A1Q3F3R6   A0A182K0N8   E2B8Q4   A0A151X3S1   A0A182VJ93   A0A182Y5V1   A0A1L8DUD3   A0A1L8DUB8   Q9NB32   A0A195EEX5   A0A0J7L083   A0A1W4X1L7   A0A195ESL8   F4WQT6   A0A182GEL1   A0A1S3D225   A0A023EWC4   A0A067RDC2   A0A158NRS2   A0A023ETP0   W5U591   B0W5S5   A0A336KPC9   A0A0K8TST0   A0A195BRM7   U5EX42   A0A195D142   A0A224XN34   A0A0A9Y6Y1   J9JSI4  

PDB

4B2T     E-value=3.33947e-165,     Score=1494

KEGG

692795    K09496 T-complex protein 1 subunit delta | (RefSeq) chaperonin subunit 4 delta

GO

GO:0005737   GO:0005524   GO:0006457   GO:0051082   GO:0005832   GO:0005829   GO:0006487   GO:0006488   GO:0007156   GO:0008237   GO:0043401   GO:0003707   GO:0051537  

Subcellular location

Cytoplasm  

Length:

537

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.12433

Exp number, first 60 AAs:

0.0006

Total prob of N-in:

0.00120

outside

1  -  537

 

 

Pi

5.277103

Theta

12.754298

Tajima's D

-1.645516

CLR

3.674301

CSRT

0.0430478476076196

Interpretation

Uncertain