Gene

KWMTBOMO07320

Pre Gene Modal

BGIBMGA010624

Annotation

PREDICTED:_cytoplasmic_dynein_2_light_intermediate_chain_1_[Papilio_polytes]

Location

Bomo_Chr12(-):10597264-10598451      View in EpiBrowser

Full name

Cytoplasmic dynein 2 light intermediate chain 1      

Location in the cell

Cytoplasmic   Reliability : 1.315 Mitochondrial   Reliability : 1.387 Nuclear   Reliability : 1.235

CDS

ATGTTTTTAGATACAGAAGCTAAAAAGATTGTCTGCAGTACTCTTAGAAGTGTGGCACTACTTAATGACGCGCATTTAATGTTTTATTCATCCAAAGAATCGATGTTAGTTAAACGAGCTAAAGACATTTTTAACAGTATTGGTTTTGAGAATGGGATTTCTATCAAAGACAAACAAACAAATCCTACAAAACCACTTTTTATAAATAAAGGGGCAGATACCTGGGAAAATATTGGGGTGGCAAGATCGACTTTCGATGAGATAAAGCAAAGGTATTACTCTAAAATACCTCTTGATTCGTCGGGTGATGTTACGACTGTTAAAACAGGACTAAAGAAGACGCACCCTGAGGCCGACATCGATAAACTCATCGCTCTCAAGTACGATGAATTACGTGAAATGGAAACACTCGAAATCGACATAATGTCCATTGTTGACTATTTATGTTAA

Protein

MFLDTEAKKIVCSTLRSVALLNDAHLMFYSSKESMLVKRAKDIFNSIGFENGISIKDKQTNPTKPLFINKGADTWENIGVARSTFDEIKQRYYSKIPLDSSGDVTTVKTGLKKTHPEADIDKLIALKYDELREMETLEIDIMSIVDYLC

Description

Required for correct intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length.

Subunit

The cytoplasmic dynein complex 2 is probably composed by a heavy chain homodimer and a number of DYNC2LI1 light intermediate chains.
The cytoplasmic dynein complex 2 is probably composed by a DYNC2H1 homodimer and a number of DYNC2LI1 light intermediate chains.

Similarity

Belongs to the dynein light intermediate chain family.

Keywords

Cell projection   Cilium   Complete proteome   Cytoplasm   Cytoskeleton   Developmental protein   Dynein   Microtubule   Motor protein   Reference proteome  

Feature

chain  Cytoplasmic dynein 2 light intermediate chain 1

Uniprot

H9JM71   A0A2A4IS59   A0A212END5   A0A2H1V2K4   A0A194PH64   A0A0L7KV48   + More
A0A182FMY4   B0WC18   A0A182SGR7   A0A336LPK3   A0A182QPE6   A0A182H6U6   Q17L39   A0A182N8N7   A0A182GWR2   A0A182UPU6   A0A182KJM6   A0A1S4H3Z3   A0A182XB13   A0A182I0K6   Q7Q0T9   A0A182TZY0   V9KV96   A0A1B6M183   A0A195FJ06   A0A2C9KJ07   A0A1J1HZZ7   A0A3L8E0U2   A0A1B6IMQ1   A0A151WTN6   A0A0L7RGM0   A0A1B6KL58   C3Z3W6   A0A158P2E1   A0A195BUA3   F4WUR5   A0A067R3F8   A0A195D381   A0A1B6FV40   R7V520   A0A195DN69   A0A3S3Q737   F6XTJ5   H3B710   A0A1B6D0W5   A0A154PRT5   A0A182P2B2   A0A3P8C129   E2AY29   W4YRZ7   S7PFS7   G1PSV8   A0A1B6E536   A0A0K2T7M3   A0A131ZXA3   A0A210PQ01   F6XTI3   A0A088A9H7   Q7SXY4   F1R764   K9J034   A0A1A9V9M5   Q32KV4   L8HRD9   A0A1B0FF89   A0A310SCK5   A0A1S3IDT3   A0A0A9ZBP8   A0A2A3EGH9   A0A1Y3ALN1   W5PA46   G3P909   A0A1W5B8J4   A0A182R7R5   A0A0P7Z0P6   G1S499  

Pubmed

19121390    22118469    26354079    26227816    26483478    17510324    + More
20966253    12364791    24402279    15562597    30249741    18563158    21347285    21719571    24845553    23254933    18464734    9215903    20798317    21993624    26555130    28812685    23594743    22751099    25401762    20809919   

EMBL

BABH01033422    NWSH01008400    PCG62571.1    AGBW02013671    OWR42998.1    ODYU01000383    + More
SOQ35077.1    KQ459603    KPI92642.1    JTDY01005321    KOB67113.1    DS231884    EDS43078.1    UFQS01000101    UFQT01000101    SSW99616.1    SSX19996.1    AXCN02001857    JXUM01114915    KQ565831    KXJ70622.1    CH477219    EAT47387.1    JXUM01093988    KQ564095    KXJ72803.1    AAAB01008980    APCN01005216    EAA13896.3    JW870431    AFP02949.1    GEBQ01013831    GEBQ01010302    JAT26146.1    JAT29675.1    KQ981523    KYN40247.1    CVRI01000037    CRK93597.1    QOIP01000002    RLU25809.1    GECU01019524    JAS88182.1    KQ982753    KYQ51198.1    KQ414594    KOC70137.1    GEBQ01027806    JAT12171.1    GG666577    EEN52880.1    ADTU01007165    KQ976408    KYM91199.1    GL888375    EGI62062.1    KK852723    KDR17682.1    KQ976885    KYN07358.1    GECZ01015778    JAS53991.1    AMQN01005091    KB295123    ELU13557.1    KQ980734    KYN13944.1    NCKU01000630    NCKU01000525    RWS14744.1    RWS15181.1    AFYH01092046    AFYH01092047    AFYH01092048    AFYH01092049    AFYH01092050    AFYH01092051    AFYH01092052    AFYH01092053    GEDC01017998    JAS19300.1    KQ435093    KZC14619.1    UZAH01026304    VDO78595.1    GL443762    EFN61625.1    AAGJ04078630    KE162063    EPQ06842.1    AAPE02005232    GEDC01004299    JAS32999.1    HACA01004733    CDW22094.1    JXLN01004552    KPM03311.1    NEDP02005562    OWF38561.1    BC055198    AL928999    GABZ01006786    JAA46739.1    BC109910    JH884041    ELR45587.1    CCAG010014241    KQ769058    OAD53013.1    GBHO01000937    JAG42667.1    KZ288254    PBC30837.1    MUJZ01070948    OTF69361.1    AMGL01077851    AMGL01077852    AMGL01077853    JARO02002004    KPP73859.1    ADFV01012241   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000037510    UP000069272    + More
UP000002320    UP000075901    UP000075886    UP000069940    UP000249989    UP000008820    UP000075884    UP000075903    UP000075882    UP000076407    UP000075840    UP000007062    UP000075902    UP000078541    UP000076420    UP000183832    UP000279307    UP000075809    UP000053825    UP000001554    UP000005205    UP000078540    UP000007755    UP000027135    UP000078542    UP000014760    UP000078492    UP000285301    UP000002279    UP000008672    UP000076502    UP000075885    UP000000311    UP000007110    UP000001074    UP000242188    UP000005203    UP000000437    UP000078200    UP000009136    UP000092444    UP000085678    UP000242457    UP000002356    UP000007635    UP000192224    UP000075900    UP000034805    UP000001073   

PRIDE

H9JM71    Q32KV4   

Pfam

PF05783   DLIC        + More
PF00640   PID
PF06311   NumbF

Interpro

IPR040045   DYNC2LI1        + More
IPR027417   P-loop_NTPase       
IPR029034   Cystine-knot_cytokine       
IPR022780   Dynein_light_int_chain       
IPR006020   PTB/PI_dom       
IPR011993   PH-like_dom_sf       
IPR010449   Numb_domain       

SUPFAM

SSF52540   SSF52540       

Gene 3D

2.10.90.10     2.30.29.30    

ProteinModelPortal

H9JM71   A0A2A4IS59   A0A212END5   A0A2H1V2K4   A0A194PH64   A0A0L7KV48   + More
A0A182FMY4   B0WC18   A0A182SGR7   A0A336LPK3   A0A182QPE6   A0A182H6U6   Q17L39   A0A182N8N7   A0A182GWR2   A0A182UPU6   A0A182KJM6   A0A1S4H3Z3   A0A182XB13   A0A182I0K6   Q7Q0T9   A0A182TZY0   V9KV96   A0A1B6M183   A0A195FJ06   A0A2C9KJ07   A0A1J1HZZ7   A0A3L8E0U2   A0A1B6IMQ1   A0A151WTN6   A0A0L7RGM0   A0A1B6KL58   C3Z3W6   A0A158P2E1   A0A195BUA3   F4WUR5   A0A067R3F8   A0A195D381   A0A1B6FV40   R7V520   A0A195DN69   A0A3S3Q737   F6XTJ5   H3B710   A0A1B6D0W5   A0A154PRT5   A0A182P2B2   A0A3P8C129   E2AY29   W4YRZ7   S7PFS7   G1PSV8   A0A1B6E536   A0A0K2T7M3   A0A131ZXA3   A0A210PQ01   F6XTI3   A0A088A9H7   Q7SXY4   F1R764   K9J034   A0A1A9V9M5   Q32KV4   L8HRD9   A0A1B0FF89   A0A310SCK5   A0A1S3IDT3   A0A0A9ZBP8   A0A2A3EGH9   A0A1Y3ALN1   W5PA46   G3P909   A0A1W5B8J4   A0A182R7R5   A0A0P7Z0P6   G1S499  

KEGG

101741206    K10417 dynein light intermediate chain 2, cytosolic | (RefSeq) cytoplasmic dynein 2 light intermedia

GO

GO:0035721   GO:0005868   GO:0005929   GO:0035735   GO:0045504   GO:0005930   GO:0036064   GO:0030990   GO:0045177   GO:1902017   GO:0035869   GO:0005813   GO:0008569   GO:0007368   GO:0031514   GO:0003774   GO:0097730   GO:0042073   GO:0007275   GO:0005874   GO:0005737  

PANTHER

PTHR13236  

Subcellular location

Cytoplasm   Localizes to the apical cytoplasm.   With evidence from 2 publications.
Cell projection   Localizes to the apical cytoplasm.   With evidence from 2 publications.
Cilium   Localizes to the apical cytoplasm.   With evidence from 2 publications.
Cytoskeleton   Localizes to the apical cytoplasm.   With evidence from 2 publications.
Cilium basal body   Localizes to the apical cytoplasm.   With evidence from 2 publications.
Cilium axoneme   Localizes to the apical cytoplasm.   With evidence from 2 publications.
Microtubule organizing center   Localizes to the apical cytoplasm.   With evidence from 2 publications.
Centrosome   Localizes to the apical cytoplasm.   With evidence from 2 publications.

Length:

149

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.02694

Exp number, first 60 AAs:

0.02694

Total prob of N-in:

0.16329

outside

1  -  149

 

 

Pi

6.536771

Theta

18.976654

Tajima's D

-1.966102

CLR

46.035087

CSRT

0.0150492475376231

Interpretation

Uncertain