SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO07312  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA010628
Annotation
PREDICTED:_E3_ubiquitin-protein_ligase_HECTD1_isoform_X1_[Bombyx_mori]
Location in the cell
Nuclear   Reliability : 2.304
 

Sequence

CDS
ATGGCAGAAGTGGATCCAGAGACATTACTGGAGTGGCTGCTGACTGGGCAGGGTGATGAACGTGATATGCAACTCATTGCTCTTGAACAGCTGTGTATGCTTCTACTAATGTCTGATAATGTTGACAGGTGTTTTGAAAGCTGTCCACCAAGAACATTTCTTCCAGCTTTGTGCAAGATTTTTTTGGATGAATGTGCACCTGATAATGTTTTAGAAGTTACTGCAAGAGCTATCACATATTATCTGGACGTGTCTGCTGAGTGTACAAGGCGCATTGTAGCAATTGAGGGAGCTGTGAAGGCTATATGCAACAGACTGTTGACAGTTGACCCCAATAATCGGACAAGTAAAGATCTAGCAGAGCAATGTATAAAGGTCTTGGAACTTGTTTGCACTCGAGAAGCCGGTGCTGTATGGGAAGGTGGTGGTTTACCTGCTGTTTTGCATTTTATTACAAACCATGGTACCTCAGTGCATAAGGATACACTACATTCAGCCATGGCTGTGGTTTCCAGGGTGTGCGGTAAGATGGAGCCCGGTGACGCTCGCGTAGGTGACGCGGTGTCGTCGTTGTCAATGCTCCTGCGTCACAGCGACGCGCGGGTGGCGGACGCAGCGCTGCGCTGCTTCGCCTCGCTCGCCGACAGGTTTGCACGCGCCCATGCCGACCCGGCGCCGTTGGCTGAACACGGCCTAATTGAAGAATTAGTACGACGTTTGGGAAGCACAGAGAGTGGAGATGATAAATGTCTCACTTCAGCCGTATCCACTACAGTCAGTCTCCTTTCGACGCTATGTCGCGGATCGGCGCAGATCACCCATGATTTAGTTCGTTTGGAATTATGTTCAGCCATTGAAAAGGCAGTTCAAGCAGATGAGCGTTGGTGCTTAGAATGTATGCGATTGGTCGACTTGTTACTAGTACTGCTCTGTGAAGGAAGGCACGCCATAGCAACGGGTGCGAACCGTAATGTCGGTTCATCATCGGGCGCGCGGTCCACGGAGGCGAGTCGCGGCGGAGAGCGCTCGCACCGGCAGCTCATCGACTGCATCCGCGGGAAGGACACGGACGCGCTGCTGTCGGCCGTGTCCAGCGGCGCCGTGGATGTTAACTTCACCGACGACGTCGGCCAGACGCTGCTCAACTGGGCCGCCGCCTTCGGCACCAAGGAGATGGTCGAGTTCCTGTGTGAGAAAGGAGCGGACGTAAATCGAGGACAGCGTAGTTCATCCCTTCATTATGCGGCTTGTTTTGGTCGTCCCGCGATTGCCAAGGTACTGCTTCGGTATGGCGCCAATGCGGATTTGCGTGACGAGGACGGTAAAACCCCATTAGACAAAGCGAGAGAGCGACACGATCAAGGGCACAGGGAAGTGGCAGCAATATTGCAATGTCCCGGAGAGTGGTTGGTTGTCGGCAACAGCGAGTCCCCGTCTCCGTCGACTGATGATGACTTTCCAGAGACGGGCGACAAAGAAATGGCTGAGTTTTACCTAGAACGGCTGGTGCCGCTGTTCTGCGCGCGGTACGTGGGCGCGGGCGGCGGCGGCGTGCGGCGCGCCTGCCTGTCGCTGGTGCGCAAGATGGTGCACTACGCGCCGCCGCGCCTGCTGCGGGACGCGCACCCCGCCGCGCTGCTCACCAACCTCGTCGCCGCCGTGCTCGACAACCAGGATGACGACGATGGACATTTGACAGTTTTGGGCATATCCGAAGAGTTGATGGCCAAGGCCGCCGACGTGTACTTGGAACAGTTCGCTCGGCTCGGCGTCTTCAGCAAAGTCGAAGCACTCGCCATCACACCCATTCAGTACGACAGCGATGGCAGCTCGACTCCAGAGCTGAGCGGCGAGGACGCGTCGTGCTTGTCGAGCGGCGTCGCGTACTCGTGGGGCGAGTGGTCGCTGTGCCGCGGCCGCGACGCGCTGTACGCGTGGAGTGACGCCGCCGCGCTCGAGCTCAGCACCGGCAGCAACGGCTGGTTCCGCTTCCTACTCGACGGCAAGCTGGCCACCATGTACTCCAGCGGCAGTCCCGAGCACCAGACCGACAACACTGAAAATCGCGGAGAGTTCATTGAAAAACTACAAAAGGCAAAAGCTTCGGTGAGAAACTTTATCCCGCAGCCGATCCTGTCGAAACCCGGTCCCAATAAACTAGTTCTCGGGAATTGGTCCTTAACATGTGAAAAGGAAAAGGAGCTGCATATATACAATATAGATGGGCAGCAACAGACCACAATATTGAAAGAGGATTTGCCGGGATTTATTTTTGAATCAAATAGAGGAACCAAACATACATTTACTGCAGAAACATTTTTAGGTCCTGACATCGCCAGTGGCTGGGCTGACAGAAGGTCATTGCTTACCAATAATTCAACACCAACAAAACCTCGTTCTCGAATATCAGCAAAAACCGAAGCTCTTAAAGCACAAGTATGTGAGCGAGCGCGTGCGCTGTACTCGCGGCACCTCGCGAGCGCAGTGACGCGCCAGCCGCGCCCGCCCGTCGCCCGCCTGCGCGCGCTGCTCGCCAGGATGCAACGCATCGCCACCCAGCCTTCCAAAGATTGGCAACGAGAGCTCAACGAATCGCTGGATCAGCTGACCGAGTTGCTGTGTGGAGATGAGCATCTGTCTGCGTATGAGTTACAGTCGTCTGGGTTAGCGCCTGCTCTACTACAGGTCCTCTCCCCACAGGTTAACGACGGTCCGGGCCACCTGTCGGAGCGCAGCCGCGTTGTGAGCGCGTGGATGTGCCGGGCGTCGGGCGCGGCTGGCGCGGCGCTGGCCGAGCGGCTGGTGGCCGTGCTGGAGTCAGTGGAGCGGCTGCCGGTGCTCGCGCCGCACGACGCGCCGCCCGCCCCCGCCTCTGCCTTGCACCACCTCACTAAGCGCATACGCTTGCGCGTCGAACGTGAAAGTGATGAAATCAGCGAAGACAGCAATGCTAATAATAACAGCGGCCGTAACCTGAAAGTGGAAGCCCTCACTACCGTCCGTCAGCTAGAACGGTTCTTGGCCAAGTCCGTAGCGCGGCAGTGGTACGACATGGAGCGGTCCACCTTCCTCTTCGTGCAAAAAATAAAAACTGAAGCTCCTTTAAGCTTCACCTACGACCACGATTTCGATGAAAACGGCGTTCTGTACTTCATCGGAACCAATGCTGGCACTTGTGAGTGGGTGAACCCTGGCGCTCACGGGCTAGTCTACGTGTGGTCATCAGACGGTAAACAGTTACCGTATGGACGACCCGAAGATGTGCTGTCGAGATCTCCAGAACCACTCAACGTGCACACTAATGACGACAGACGCGCTTTCATTGCATTGGACTTAGGCGTTCATATTGTACCAACCGCATACACCTTACGTCACGCCCGTGGCTACGGGCAATCAGCATTGCGGAATTGGCTTTTTCAAATGTCAGTAGACGGCTTGACGTGGTGTACGTTGGTGGCACACACGGACGAGCAGGCGCTGCAGGAGCCGGGCAGCACGGCCACCTGGCGCCTCCGCACGGATTCATCCTATCGATATCTTCGCATACAGCAAAACGGAAAAAATGCGAGCGGTCAAAAATACTACCTTTCACTCTCCGGGCTAGAGATCTACGGAAAGGTGACAGGAGTGGTGGAGACGGCGCCACGACAAAGCGGTGCCCCGCATCAGACCACGGGCACGACGGCGAGCAGCGCATGTAACAACGCTACCGCGGCGAACAACACGAACAACGCCGGCATGGCGGGCGGCGGCGGCGGCGCGCGGGCGCGGCGGTGGTCGCGCGGCCGCGGCGTGTGTGCGGGCGCGCGCGTCTCCCGCGGCCCCGACTGGAAGTGGCGCGACCAGGACGGGCCGCACCCCGCACTCGGCACTCTCACTTCCGAACTGCACAACGGGTGGGTCGATGTCAGGTGGGACCACGGAGTTCGCAATTCGTATCGCATGGGTGCAGAGGGAAAGTTCGACTTGAAAGTTGTGAGCGGTGGTACTGTCATCGAAAGTTCAAAAGCCAGCCGGAAGAGTCACTCAACTCCCAGTTTGCCTGACGCCACTTCTGTCGATCAGGTATCAGTAGCGTCGACGGAACAGGCCTCGTCAGCGGACAATATATCGAGTGAAGAGATGGTCAGTAATATGTCAAGACCCCGTACGCACGCCACAGATCTCTCTGCCATTAATAATTCGACGCATCATATAAACTCTGTGTTTGACATAGATCTCGCGACAATAGTGGAGTCATTGACGTTGGGCGCCGAAAGTAACAATTGCATCACCGAGTTGGGGAATACATCGTTTACCAACATGGAAATGGGACCTACGAGCATTACGGATATCACCAAACCTTATCCCGCCAAAGAGCCGTTACCCGAATCCAGTGCACACGAGTGCGACGAAAATGAAGCCGGGGAAAGTCAATACGGTGATAATAAGAAGGAAAGTCAGTCCGGTTCGGGCACCATGAGCGCTAGCGAACCTGATTTGACGCAGCAGGGCACAGGACGCCTGTTGGAGTCGCTGGGCGTGGGCCGCGGCAACAGTGCAGGACGAGGCAGCAACGTGCCGCGCTCGAACCGTAACAATCATTCCTCTGGTCTCCTACCTAGTTTGGTGCGTTTAGCGTTGTCGAGCAACTTCCCCGGCGGGCTGCTGTCGGCGGCGCAGAGCTACCCCTCGCTGTCGTCCAACGCGCAGAACGCGCTCACGCTGTCGCTCACATCCACGTCCAGCGAAAGCGAACAGGTCTCATTAGAAGACTTTTTGGAGTCTTGTCGTGCTCCCGCGTTGTTGACAGAGTTGGAAGATGATGAAGACGGTGATGAGGCGCTGGACAGCGACAAAGAGAACGAACCCACTTACCAGGAGGTAGTCAGTAAACTTTTGGTATCTCGTAATTTGCTCTCTCTGATGGAGGAAGAAGCTTTAGAGGCTCTACGTGGCAGCTCGGGATCTGGACAAAACAATCGCTCGCGCCGACCCTGGGACGACGACTTCGTGCTCAAGCGACAGTTCTCAGCGCTCATACCGGCCTTCGATCCTCGCCCGGGAAGAACGAATCTCAACCAAACTGTCGATCTCGAAATACCTCTGAACGAGGAGTCCGAAGAGGAGGAGAGTTGGGAAGAAGTGCCAGAGAACGTCGGCGGCGGCGCGACTAGCGAGACCGGTCGCGCCCCGGCGCTGCGCCTGGTACTGAGCGCGGGCGGGGCCTCGCTGCCGCTGGCGCGCGGCTCCTGGACGCTGTACCGCGCCGTGCTGCTGCTGCACGCCCGCCTGCCGCACGCAGACCTCCATCGAGATACCACATACACTTTAACATACAAGGAGGTGGAGGGTTCAGAGGGCGCATTTGCTTCGAGTGACACTGAAGATGATGAACCTAATGATCCAGAAGGCGGTATAGTGGGTGCAGAGGGGAGCGAGGGCGGCATGGCCACGAGCTGCGTGCGCGTGCTGCGGCGCCTGCGAGCGGCCGCGCCCGAGCTGCCCGCCGAGCCCTTCCTCTCCACCAAGCTCACCAACAAGCTGCATCTCCAGCTGCAGGAGCCGCTCGCGCTCGCCGCCGCCGCCACTCCGCATTGGTGTCAGCAACTGATCGATTGGTGTCCATTTCTGTTTCCACTCGAAACAAGACAAATGTTTTTCGCATGCACCGCGTTTGGAACGTCCCGGACCATCGTCTGGCTGCAAGCGCAACGTGACCGTGCTTTGGACAGACAGAGAGCGACCAACACGGTGTCACCGCGCCGAGCGGAGCTGGAAGCGACTGAATTCCGCATGGGTCGCCTCAGACACGAGCGCGTTCGGATTCCGAGAGATCCCGACATGCTGCGTTCTGCTATTCAGGTGATGCGAGTGCACGCGAGTCGCAAGTCTGTATTAGAGGTGGAATTCGCGGGCGAGGAGGGCACTGGTCTCGGGCCCACGCTGGAGTTCTACGCGCTGGTGGCGGCCGAGCTGCAGCGCGCCGACCTCGCCCTGTGGCTGCACGACGCGCCGCTGCACGTCGATGACGACGCGCCGCTGCACCTCATGCAGCCCACAGAAAAGCCACCCGGTTACTACGTGAGCCGGCCCGGTGGCCTGTTTCCGGCTCCACTTCCGCAAGAATCCCCTATCTGTGATAAAGTGTGCAAATATTTCTGGTTTTTAGGAGTATTTTTAGCTAAGGTATTACAAGACGGCCGACTAGTTGACTTGCCTCTGTCAGAGCCGTTCTTACGTATAATGTGTGGTGAAGAGTTAACGAAAGAGAATTTACAAGAAATCGATCCCATTAGACATAGATTCTTAGAGAAGATGCTCGAAGCAGCCGAGGGGTACGACAAAATAATGCGTGATGAATCCTTGGACGAGAACGAGAAGCAGAAACGTGTCAGTGAGTTAAATGTAGACGGCGCCGCTTTTGAAGAATTGTCTTTAACTATGACGCACATCGCACCCAACGTCGACCCCGCTGTCGCCGTGCAACCGCTCTGTGATGGCGGAGAACATATCGAGGTGGGCGCGCACAACGCTCGTCTGTACGCGGAGTGGAGCGCGCGCTGGATGGTGTCGGCGGGCGTGCGGCGCCAGGTGGCGTGGTTCAAGCGCGGGTTCGCACGCGTGTTCCCGCCGCGACGCCTGCGGGCCTTCTCTCCTTCCGAGCTGCGCCTGCTGCTCTGCGGGGAACGCGGCCCCGTCTGGACCAGGGAACATCTGCTGCAGTATACCGAGCCTAAACTCGGATACACCAGAGATAGTCCGGGATTCCTTCGTCTGGTTGACGTTCTGGTTGAGATGTCGATCTGCGAGCGTAAAGCATTCCTGCAGTTCGCGACGGGATGCAGCAGCCTGCCGCCCGGCGGACTCGCCAACCTGCATCCTCGACTCACGGTCGTACGGAAGGTCGACGCCGGAGATGGATCGTACCCTTCAGTGAACACCTGCGTGCACTACCTGAAGTTGCCCGAGTATTCGTGTAAGGAAGTGCTACGCGAACGTTTGCTGGCCGCGACCAACGAGCGCGGCTTTCATTTAAATTAA
Protein
MAEVDPETLLEWLLTGQGDERDMQLIALEQLCMLLLMSDNVDRCFESCPPRTFLPALCKIFLDECAPDNVLEVTARAITYYLDVSAECTRRIVAIEGAVKAICNRLLTVDPNNRTSKDLAEQCIKVLELVCTREAGAVWEGGGLPAVLHFITNHGTSVHKDTLHSAMAVVSRVCGKMEPGDARVGDAVSSLSMLLRHSDARVADAALRCFASLADRFARAHADPAPLAEHGLIEELVRRLGSTESGDDKCLTSAVSTTVSLLSTLCRGSAQITHDLVRLELCSAIEKAVQADERWCLECMRLVDLLLVLLCEGRHAIATGANRNVGSSSGARSTEASRGGERSHRQLIDCIRGKDTDALLSAVSSGAVDVNFTDDVGQTLLNWAAAFGTKEMVEFLCEKGADVNRGQRSSSLHYAACFGRPAIAKVLLRYGANADLRDEDGKTPLDKARERHDQGHREVAAILQCPGEWLVVGNSESPSPSTDDDFPETGDKEMAEFYLERLVPLFCARYVGAGGGGVRRACLSLVRKMVHYAPPRLLRDAHPAALLTNLVAAVLDNQDDDDGHLTVLGISEELMAKAADVYLEQFARLGVFSKVEALAITPIQYDSDGSSTPELSGEDASCLSSGVAYSWGEWSLCRGRDALYAWSDAAALELSTGSNGWFRFLLDGKLATMYSSGSPEHQTDNTENRGEFIEKLQKAKASVRNFIPQPILSKPGPNKLVLGNWSLTCEKEKELHIYNIDGQQQTTILKEDLPGFIFESNRGTKHTFTAETFLGPDIASGWADRRSLLTNNSTPTKPRSRISAKTEALKAQVCERARALYSRHLASAVTRQPRPPVARLRALLARMQRIATQPSKDWQRELNESLDQLTELLCGDEHLSAYELQSSGLAPALLQVLSPQVNDGPGHLSERSRVVSAWMCRASGAAGAALAERLVAVLESVERLPVLAPHDAPPAPASALHHLTKRIRLRVERESDEISEDSNANNNSGRNLKVEALTTVRQLERFLAKSVARQWYDMERSTFLFVQKIKTEAPLSFTYDHDFDENGVLYFIGTNAGTCEWVNPGAHGLVYVWSSDGKQLPYGRPEDVLSRSPEPLNVHTNDDRRAFIALDLGVHIVPTAYTLRHARGYGQSALRNWLFQMSVDGLTWCTLVAHTDEQALQEPGSTATWRLRTDSSYRYLRIQQNGKNASGQKYYLSLSGLEIYGKVTGVVETAPRQSGAPHQTTGTTASSACNNATAANNTNNAGMAGGGGGARARRWSRGRGVCAGARVSRGPDWKWRDQDGPHPALGTLTSELHNGWVDVRWDHGVRNSYRMGAEGKFDLKVVSGGTVIESSKASRKSHSTPSLPDATSVDQVSVASTEQASSADNISSEEMVSNMSRPRTHATDLSAINNSTHHINSVFDIDLATIVESLTLGAESNNCITELGNTSFTNMEMGPTSITDITKPYPAKEPLPESSAHECDENEAGESQYGDNKKESQSGSGTMSASEPDLTQQGTGRLLESLGVGRGNSAGRGSNVPRSNRNNHSSGLLPSLVRLALSSNFPGGLLSAAQSYPSLSSNAQNALTLSLTSTSSESEQVSLEDFLESCRAPALLTELEDDEDGDEALDSDKENEPTYQEVVSKLLVSRNLLSLMEEEALEALRGSSGSGQNNRSRRPWDDDFVLKRQFSALIPAFDPRPGRTNLNQTVDLEIPLNEESEEEESWEEVPENVGGGATSETGRAPALRLVLSAGGASLPLARGSWTLYRAVLLLHARLPHADLHRDTTYTLTYKEVEGSEGAFASSDTEDDEPNDPEGGIVGAEGSEGGMATSCVRVLRRLRAAAPELPAEPFLSTKLTNKLHLQLQEPLALAAAATPHWCQQLIDWCPFLFPLETRQMFFACTAFGTSRTIVWLQAQRDRALDRQRATNTVSPRRAELEATEFRMGRLRHERVRIPRDPDMLRSAIQVMRVHASRKSVLEVEFAGEEGTGLGPTLEFYALVAAELQRADLALWLHDAPLHVDDDAPLHLMQPTEKPPGYYVSRPGGLFPAPLPQESPICDKVCKYFWFLGVFLAKVLQDGRLVDLPLSEPFLRIMCGEELTKENLQEIDPIRHRFLEKMLEAAEGYDKIMRDESLDENEKQKRVSELNVDGAAFEELSLTMTHIAPNVDPAVAVQPLCDGGEHIEVGAHNARLYAEWSARWMVSAGVRRQVAWFKRGFARVFPPRRLRAFSPSELRLLLCGERGPVWTREHLLQYTEPKLGYTRDSPGFLRLVDVLVEMSICERKAFLQFATGCSSLPPGGLANLHPRLTVVRKVDAGDGSYPSVNTCVHYLKLPEYSCKEVLRERLLAATNERGFHLN

Summary

Catalytic Activity
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
Pfam
PF07738   Sad1_UNC        + More
PF00632   HECT
PF06701   MIB_HERC2
PF12796   Ank_2
Interpro
IPR012919   SUN_dom        + More
IPR000569   HECT_dom       
IPR016024   ARM-type_fold       
IPR020683   Ankyrin_rpt-contain_dom       
IPR035983   Hect_E3_ubiquitin_ligase       
IPR008979   Galactose-bd-like_sf       
IPR036770   Ankyrin_rpt-contain_sf       
IPR002110   Ankyrin_rpt       
IPR011989   ARM-like       
IPR037252   Mib_Herc2_sf       
IPR010606   Mib_Herc2       
SUPFAM
SSF48403   SSF48403        + More
SSF48371   SSF48371       
SSF159034   SSF159034       
SSF56204   SSF56204       
SSF49785   SSF49785       
PDB
4Y07     E-value=1.03204e-21,     Score=262

Ontologies

Topology

Length:
2340
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.01445
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00002
outside
1  -  2340
 
 

Population Genetic Test Statistics

Pi
17.42374
Theta
17.010542
Tajima's D
-0.979552
CLR
0.654885
CSRT
0.138543072846358
Interpretation
Uncertain
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