Gene

KWMTBOMO07290  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010636

Annotation

PREDICTED:_multidrug_resistance-associated_protein_7_[Papilio_machaon]

Location

Bomo_Chr12(-):10043989-10058977      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.717

CDS

ATGTCTTTTATATTGAATATAAATTGGAAATGGGAAGATATGTGCGGGCCTGGAGGGCTTCATCCATGGAATGATGCCACGAAAGACTTCAGCGTGTGTTTTCAAGAGCTATTCTTACAAGTACCAGTGTACTTTATAATAGCTATAGTATCAGGGTATTTTGTTGGATATCGAAAAGATTGGGTGATACGAGAAAAAACTCAAGAACGTGCCATAATATTTCGAAGTTTTGTTGTTTTAGGCTTAGCCTTCATACCGATCATAGAAATATATATATTTACTACCAAACCTGACTTCACTCTATATCCAGTAGACTATTTTGCTGCTGGTTCATCCTGTTTAGCATGGCTGGTGCACTTTGGATATGTTTTAGCATTGAAACACCGTCTTGGGCGTAGCTCTCGAGGTTTCAATACAGCTGCATTATGTTGTCACGTACTGTATTTTTTAACTCTGATTCCTTCAAATTACTCACGACCAACATTTTACTCGCCATGCTTAGTAGGCTCCCAACACTCTCATAGCGAGTACACTCCACTGATACCCCATGTAGATGATGATGTTCTTGGTACAGCTATGCAGGGCAACAGCTTTTTTTCAAAGTTGATGTTTACTTGGGTGAACCCTTTGCTACAAAAAGGTCTGGAGAATAAACTAAAAGATCCTGAAGAACTTTTCGACATACCAGCAGAATATCGTAGTTCATATATTGGTGCCAGAATGGATCGAGCATTGGTTGGAAATGTTGATCATCACCAACAATATGCTGATATACCACATGAACCTTTTATAAGCACAGGATATGGAGCTATAGGTGAAACAGTGCCACAAGCCTCAACACCTGTAACATCAACATCACGAGTTCGGGTCCACCCCGTACGACGACAAAATGTTTCCTTATTACGAGCACTGCATAAGGTTTTTGCAGTAGAGTTTTACAGTATTGGTTTACTTAAATTGGTATCTGATATGGCAGGTTTTGCAGGACCTCTTTTATTGAATAAGTTGGTTGAATTTGTTGAAGATACTACAATTGATGAACATATTGGGTATACTTTTGCAGTTAGTCTTTTGATAGCAACATTAGGATCGACCATATTTATTGTCCAATTTAATTGGTTAATGTCCATAATTGGACTAAAGATGCGTGGTGCGCTAGTCACCACCATTCTAAGGAAAACCTTAAGTGTGACTTCAACTGAGCTGACTAAAGCGTTCTCTGTTGGTGAAATAACAAATTTTATGTCTACTGATACTGATAGGATTGTGAATTCATGTCCTAGTTTTCATGCTCTATGGAGTATACCATTACAGTTATTTATAACACTGTTTTTATTGTATCAACAAGTGGGACTATCTTTCCTTGCTGGAGTAGGCTTTTCAGTTATTCTAATACCAATAAACAAACTTATTGCAAATAAAATTGGGCAATTAAGCACAGAGTTGATGAAGCATAAGGACACTAGAGTCAGTTTGATCAGTGATTTGCTAAAAGGAATTAGAACTGTAAAGGTTCATGTTTGGGAAGATTATTTTGTGGACAGAGTATCAGGGGCACGTGCAGAAGAGATGCGTTACCTCCGAGGCCGCAAGTATTTGGACGCGGTATGTGTTGTATTGTGGGCTACAACACCGGTGCTGGTCGCAGCACTGACGCTTGGTACACATGCGCTGCGGGGACAACCCCTAGAAGCACCGACTGTATTTACAACAGTTGCCTTAATAAATATGTTGATAGCTCCATTGAATGCGTTTCCTTGGGTCCTGAACGGCCTCACAGAGGCTTGGGTTTCAATAAAACGAATACAGAAGCTTTTGGATTTACCGGACATGAATTCGGAGGAGTACTACGACCGTGTCAACGTGAACAGAGATGAAGATAAAATAATAATATTCAGAAACGCTACTTTTGCGTGGGCCAGACCTATGAAACGAGATAATATGAAGTTAAATAAAGAAAAGGGGAAGTCGAATAAGAATAAACGAAAGCTTAATATTCAGAGGAGTGATTCTCTCACGTCCGAAGAAGGCGGACAAGATGCGCCCTTTACATTGAAGGATATATCATTAGAAATTGGAAGAGAAGAATTTATAGGTGTGACCGGATCTATTGGTAGCGGAAAAACATCTTTACTGCTGGCTGTTATTGGTGAAATGTTAAAGAAAAATGGAGATCTTCAACTTCCAGAAAGTCTCAACAGCTTTGGATACGTAGCACAAAAGCCATGGTTAATACGTGGGACTATTCGTGATAATATTTTGTTCGGGAAACCTTATGACGAAACAAAATTTAAATCGGTGATCGACGCATGTGCTTTAACAGAAGATTTAAATGTACTCGGTTGGAACGCGTATGTCGGTGAAGGTGGATGTACGCTAAGCGGAGGACAGCGTGCTAGAATCGCTTTGGCACGAGCTGTATATCAAGATAAACAAGTATACTTATTGGACGATGTGTTGGCGGGTCTGGATGCCCGTGTGTCGCAGCACGTGTTACAACACTGCCTGATGGGCTTGTTGCGACACACGACGCGACTGTTCGTCGCACAATCACCGAAACATCTAGCTAGAGTCTCACGTCTACTGGTACTGCGTGAAGGCCGTATAGTTAACGAAGGACCCCCTGAAATGATCTTACACGATATTGAGGAATATTTGCCAAGTGATTCAGAATCTTTGGGAGACGATCTTCCTAGGCAAAAACAGATTGAACAATCTGATGAAGATAACATCAGCAGAAATAGCTTGGATGATGAAGAAACAGTGTCAGAAGGAACCGTCGGTTTTTGGGTCATTGGATTATATTTGAAATCAGTTGGAATATTTCTCACTGTCGCAATAACGCTATCTCTAATACTAATGCAAGTCTCGCAGAATTTCACATTCTTTTGGCTAACGATATGGTTGAAGAACAGAACTAAGAATTCTACAGCTCTGACCGACTCTGAGTTCAATTTTCACGAGAACACGACTGTTCTAGACCATAGCTTTAACGCTGTAGACGGCATCGTTCATAAACTCATCAACACGACAATGATGTTGATAAATTCTATTGACGGGCATAAAAACAATGTCAGCGAGCCATCATTAAGCTCGACCCTCACTAATGCCCGTGCGACACTAGAAATCAGTATACCACAGTACAACGACAACTTCTACTTGGAAGCGTACTTCGGATTGGCTGGATTAAATCTTGTGTTCACTGTAATGAGGGCTTTCCTCTTCGCTTATGGAGGCGTGAAAGCAGCTACTAAAATACACAAAGTGCTTTTGAAAGTTATTGTCAGGGCACAAGTGAAATTTTTTGACGTCACTCCTATTGGAAGAATTGTTAATCGTTTTTCATCTGACACGTATACAGTTGACGATTCGTTACCTTTTATTTTGAATATACTTTTGGCTCAATTCTTTTCTCTCATTGGCGCACTGGCGGTGACAATATACGGGTTGCCGTGGCTGCTGGTGGGCGTGGCGCCCCTCGCCTTCGTGTACTACCGGCTGCAGCGCGTCTACCGCATCACCTCGCGACAACTGAAACGTCTACAGAGCGTCACTCTCTCCCCTATCTACACGCACTTCAACGACACCCTCGAAGGTTTGAGTAGCATACGCGCGCTGGGCGGCGCGGCGGCGTGGGAGGAGCGCGGCTGCGAACTCGTGGAGTCGTGGCAGCGTGCGGCGCTCAGCGCGAGCGGCGCGGCGCAGTGGCTGGCGCTGCGACTGCAGGCCGCCGCCGCCGTTCTCGTGGTAGCGGCCGCCGCGCTGGCTGTGCTGCAGAGGACGCTGCACACCGCCGACCCAGGGTTGGTGGGTCTGGCGATATCCTACGCGCTATCCATGACTTCGATGTTGAGCAATGTGCTCAATTCTTTTACGGAAACCGAACGAGAAATGATAGCCGTCGAAAGGGTAGGAGAATATATTAGACAGGTTGAAATTGAGAGTGTCGACGGTGAATCTCCTCCATACGGTTGGCCGTCACATGGCGTTGTTGAGTTTGATGATGTCCACCTTAACTACAGGTAA

Protein

MSFILNINWKWEDMCGPGGLHPWNDATKDFSVCFQELFLQVPVYFIIAIVSGYFVGYRKDWVIREKTQERAIIFRSFVVLGLAFIPIIEIYIFTTKPDFTLYPVDYFAAGSSCLAWLVHFGYVLALKHRLGRSSRGFNTAALCCHVLYFLTLIPSNYSRPTFYSPCLVGSQHSHSEYTPLIPHVDDDVLGTAMQGNSFFSKLMFTWVNPLLQKGLENKLKDPEELFDIPAEYRSSYIGARMDRALVGNVDHHQQYADIPHEPFISTGYGAIGETVPQASTPVTSTSRVRVHPVRRQNVSLLRALHKVFAVEFYSIGLLKLVSDMAGFAGPLLLNKLVEFVEDTTIDEHIGYTFAVSLLIATLGSTIFIVQFNWLMSIIGLKMRGALVTTILRKTLSVTSTELTKAFSVGEITNFMSTDTDRIVNSCPSFHALWSIPLQLFITLFLLYQQVGLSFLAGVGFSVILIPINKLIANKIGQLSTELMKHKDTRVSLISDLLKGIRTVKVHVWEDYFVDRVSGARAEEMRYLRGRKYLDAVCVVLWATTPVLVAALTLGTHALRGQPLEAPTVFTTVALINMLIAPLNAFPWVLNGLTEAWVSIKRIQKLLDLPDMNSEEYYDRVNVNRDEDKIIIFRNATFAWARPMKRDNMKLNKEKGKSNKNKRKLNIQRSDSLTSEEGGQDAPFTLKDISLEIGREEFIGVTGSIGSGKTSLLLAVIGEMLKKNGDLQLPESLNSFGYVAQKPWLIRGTIRDNILFGKPYDETKFKSVIDACALTEDLNVLGWNAYVGEGGCTLSGGQRARIALARAVYQDKQVYLLDDVLAGLDARVSQHVLQHCLMGLLRHTTRLFVAQSPKHLARVSRLLVLREGRIVNEGPPEMILHDIEEYLPSDSESLGDDLPRQKQIEQSDEDNISRNSLDDEETVSEGTVGFWVIGLYLKSVGIFLTVAITLSLILMQVSQNFTFFWLTIWLKNRTKNSTALTDSEFNFHENTTVLDHSFNAVDGIVHKLINTTMMLINSIDGHKNNVSEPSLSSTLTNARATLEISIPQYNDNFYLEAYFGLAGLNLVFTVMRAFLFAYGGVKAATKIHKVLLKVIVRAQVKFFDVTPIGRIVNRFSSDTYTVDDSLPFILNILLAQFFSLIGALAVTIYGLPWLLVGVAPLAFVYYRLQRVYRITSRQLKRLQSVTLSPIYTHFNDTLEGLSSIRALGGAAAWEERGCELVESWQRAALSASGAAQWLALRLQAAAAVLVVAAAALAVLQRTLHTADPGLVGLAISYALSMTSMLSNVLNSFTETEREMIAVERVGEYIRQVEIESVDGESPPYGWPSHGVVEFDDVHLNYR

Uniprot

H9JM83   A0A2H1VZV8   A0A2A4K1G3   A0A2H4KB74   A0A3S2TBX0   A0A194PHD2   + More
A0A0N1IIP7   A0A1Y1JUE0   D1ZZF5   A0A067R2C8   A0A2J7RC39   A0A0C9Q1X6   A0A1B6CRI6   E9IEN2   A0A195EXU2   E0W3B6   E2BGH7   A0A151IB39   E2B0Q4   A0A0M8ZZW6   F4WW31   A0A087ZZ50   A0A195E724   A0A195B201   A0A151XK74   A0A2A3EF15   A0A0L7QU08   A0A154PDF4   A0A026WYM4   A0A0P5ZKY6   A0A0P6IG45   A0A158V3H1   A0A182QDF7   B0WBK8   A0A0N7ZM10   A0A0P4YBC8   A0A0P5AJP4   A0A369SEL5   A0A182RBN2   A0A182JT80   A0A0N8C5J9   Q175L6   A0A0P5Q362   A0A2C9JJ82   A0A182WT98   A0A182L255   A0A182HV92   B3RPF6   A0A182MWB3   A0A0P5Y477   A0A1S4GWP9   A0A182V448   A0A182PME8   A0A182W9Q5   A0A1S3ISY9   A0A3R5USW7   Q7Q3J7   A0A210QX53   A0A0K8UQB3   A0A034WGG1   A0A1X7UR56   A0A3M6T5D3   V3ZSB2   A0A3R7STK5   B4JBW3   A0A1I8MTN2   A0A2S2R029   A0A3Q2U413   A0A093GK30   A0A0L8GKG7   B4LSH8   A0A3M0KHC8   A0A2P4T3U5   A0A091MBD0   A0A087RAS9   A0A2S2P027   A0A091GMD4   A0A226NCW2   H0ZFL1   A0A091TYX9   A0A2B4RIZ1   G1NEX8   R0LUI4   A0A2H4TET3   A0A094MU59   A0A091QJ74   A0A093C0X3   J9K9T6   U3KC33   A0A1A9ZDC1   T1JAN3   A0A091KWU7   A0A3B3S0F4   U3I751   A0A3B3RZR6   A0A162CN38   A0A1D2N8A3   W5UJP4   A0A091N4D6   A0A3B3RZZ8  

Pubmed

19121390    26354079    28004739    18362917    19820115    24845553    + More
21282665    20566863    20798317    21719571    24508170    30249741    30042472    17510324    15562597    20966253    18719581    12364791    28812685    25348373    30382153    23254933    17994087    25315136    15592404    20360741    20838655    29121518    29240929    23749191    27289101    23127152    23696857   

EMBL

BABH01033361    ODYU01005347    SOQ46102.1    NWSH01000241    PCG78087.1    KY484780    + More
ASS36022.1    RSAL01000545    RVE41407.1    KQ459603    KPI92717.1    KQ459752    KPJ20191.1    GEZM01100368    GEZM01100367    JAV52914.1    KQ971338    EFA02360.2    KK852758    KDR17053.1    NEVH01005887    PNF38406.1    GBYB01007988    JAG77755.1    GEDC01021139    JAS16159.1    GL762653    EFZ20964.1    KQ981914    KYN33105.1    DS235882    EEB20122.1    GL448189    EFN85170.1    KQ978125    KYM96883.1    GL444666    EFN60726.1    KQ435804    KOX73033.1    GL888404    EGI61620.1    KQ979579    KYN20667.1    KQ976662    KYM78317.1    KQ982038    KYQ60789.1    KZ288269    PBC29872.1    KQ414743    KOC61936.1    KQ434878    KZC09882.1    KK107063    QOIP01000005    EZA61102.1    RLU22246.1    GDIP01045832    JAM57883.1    GDIQ01004970    JAN89767.1    KF828788    AIN44105.1    AXCN02000870    DS231880    EDS42543.1    GDIP01232257    JAI91144.1    GDIP01231010    JAI92391.1    GDIP01198015    JAJ25387.1    NOWV01000016    RDD45365.1    GDIQ01112667    JAL39059.1    CH477398    EAT41786.1    GDIQ01129919    JAL21807.1    APCN01002502    DS985242    EDV28182.1    AXCM01005667    GDIP01064787    JAM38928.1    AAAB01008964    MH172502    QAA95909.1    EAA12438.4    NEDP02001434    OWF53286.1    GDHF01025526    GDHF01023430    JAI26788.1    JAI28884.1    GAKP01005752    JAC53200.1    RCHS01004289    RMX36590.1    KB203274    ESO85415.1    QCYY01001898    ROT74442.1    CH916368    EDW04066.1    GGMS01013947    MBY83150.1    AADN05000005    KL215893    KFV67149.1    KQ421476    KOF77359.1    CH940649    EDW64800.1    QRBI01000106    RMC12638.1    PPHD01009816    POI31040.1    KK527949    KFP68816.1    KL226263    KFM10583.1    GGMR01010043    MBY22662.1    KL447610    KFO75252.1    MCFN01000094    OXB65433.1    ABQF01042276    KK491849    KFQ63736.1    LSMT01000545    PFX16450.1    KB742809    EOB04098.1    KY849651    ATY74529.1    KL349583    KFZ58056.1    KK797930    KFQ26676.1    KL452479    KFV06729.1    ABLF02024436    ABLF02024437    ABLF02024444    AGTO01000393    JH432001    KK761580    KFP45114.1    ADON01047084    ADON01047085    LRGB01000944    KZS14786.1    LJIJ01000167    ODN01206.1    JT412570    AHH39902.1    KL376455    KFP84241.1   

Proteomes

UP000005204    UP000218220    UP000283053    UP000053268    UP000053240    UP000007266    + More
UP000027135    UP000235965    UP000078541    UP000009046    UP000008237    UP000078542    UP000000311    UP000053105    UP000007755    UP000005203    UP000078492    UP000078540    UP000075809    UP000242457    UP000053825    UP000076502    UP000053097    UP000279307    UP000075886    UP000002320    UP000253843    UP000075900    UP000075881    UP000008820    UP000076420    UP000076407    UP000075882    UP000075840    UP000009022    UP000075883    UP000075903    UP000075885    UP000075920    UP000085678    UP000007062    UP000242188    UP000007879    UP000275408    UP000030746    UP000283509    UP000001070    UP000095301    UP000000539    UP000053875    UP000053454    UP000008792    UP000269221    UP000053286    UP000053760    UP000198323    UP000007754    UP000225706    UP000001645    UP000007819    UP000016665    UP000092445    UP000261540    UP000016666    UP000076858    UP000094527   

PRIDE

H9JM83   

Pfam

PF00005   ABC_tran        + More
PF00664   ABC_membrane

Interpro

IPR003439   ABC_transporter-like        + More
IPR017871   ABC_transporter_CS       
IPR036640   ABC1_TM_sf       
IPR011527   ABC1_TM_dom       
IPR027417   P-loop_NTPase       
IPR003593   AAA+_ATPase       

SUPFAM

SSF90123   SSF90123        + More
SSF52540   SSF52540       

Gene 3D

1.20.1560.10    

ProteinModelPortal

H9JM83   A0A2H1VZV8   A0A2A4K1G3   A0A2H4KB74   A0A3S2TBX0   A0A194PHD2   + More
A0A0N1IIP7   A0A1Y1JUE0   D1ZZF5   A0A067R2C8   A0A2J7RC39   A0A0C9Q1X6   A0A1B6CRI6   E9IEN2   A0A195EXU2   E0W3B6   E2BGH7   A0A151IB39   E2B0Q4   A0A0M8ZZW6   F4WW31   A0A087ZZ50   A0A195E724   A0A195B201   A0A151XK74   A0A2A3EF15   A0A0L7QU08   A0A154PDF4   A0A026WYM4   A0A0P5ZKY6   A0A0P6IG45   A0A158V3H1   A0A182QDF7   B0WBK8   A0A0N7ZM10   A0A0P4YBC8   A0A0P5AJP4   A0A369SEL5   A0A182RBN2   A0A182JT80   A0A0N8C5J9   Q175L6   A0A0P5Q362   A0A2C9JJ82   A0A182WT98   A0A182L255   A0A182HV92   B3RPF6   A0A182MWB3   A0A0P5Y477   A0A1S4GWP9   A0A182V448   A0A182PME8   A0A182W9Q5   A0A1S3ISY9   A0A3R5USW7   Q7Q3J7   A0A210QX53   A0A0K8UQB3   A0A034WGG1   A0A1X7UR56   A0A3M6T5D3   V3ZSB2   A0A3R7STK5   B4JBW3   A0A1I8MTN2   A0A2S2R029   A0A3Q2U413   A0A093GK30   A0A0L8GKG7   B4LSH8   A0A3M0KHC8   A0A2P4T3U5   A0A091MBD0   A0A087RAS9   A0A2S2P027   A0A091GMD4   A0A226NCW2   H0ZFL1   A0A091TYX9   A0A2B4RIZ1   G1NEX8   R0LUI4   A0A2H4TET3   A0A094MU59   A0A091QJ74   A0A093C0X3   J9K9T6   U3KC33   A0A1A9ZDC1   T1JAN3   A0A091KWU7   A0A3B3S0F4   U3I751   A0A3B3RZR6   A0A162CN38   A0A1D2N8A3   W5UJP4   A0A091N4D6   A0A3B3RZZ8  

PDB

6BHU     E-value=3.72429e-92,     Score=868

KEGG

101745183    K05674 ATP-binding cassette, subfamily C (CFTR/MRP), member 10 | (RefSeq) multidrug resistance-assoc

PATHWAY

02010    ABC transporters - Bombyx mori (domestic silkworm)

GO

GO:0016021   GO:0042626   GO:0005524   GO:0016020   GO:0055085   GO:0032440   GO:0016887   GO:0006810   GO:0007156   GO:0008237   GO:0043401   GO:0003707   GO:0051537  

Length:

1341

Number of predicted TMHs:

13

Exp number of AAs in TMHs:

319.653

Exp number, first 60 AAs:

20.78587

Total prob of N-in:

0.00371

POSSIBLE N-term signal

sequence

outside

1  -  36

TMhelix

37  -  56

inside

57  -  71

TMhelix

72  -  94

outside

95  -  103

TMhelix

104  -  126

inside

127  -  348

TMhelix

349  -  371

outside

372  -  444

TMhelix

445  -  467

inside

468  -  534

TMhelix

535  -  557

outside

558  -  566

TMhelix

567  -  589

inside

590  -  930

TMhelix

931  -  953

outside

954  -  1055

TMhelix

1056  -  1078

inside

1079  -  1123

TMhelix

1124  -  1146

outside

1147  -  1149

TMhelix

1150  -  1167

inside

1168  -  1235

TMhelix

1236  -  1258

outside

1259  -  1267

TMhelix

1268  -  1290

inside

1291  -  1341

 

 

Pi

25.907992

Theta

23.100717

Tajima's D

0.401608

CLR

0.569426

CSRT

0.489525523723814

Interpretation

Uncertain