Gene

KWMTBOMO07278  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010642

Annotation

PREDICTED:_uridine_phosphorylase_1_isoform_X2_[Papilio_xuthus]

Location

Bomo_Chr12(-):9899198-9918837      View in EpiBrowser

Full name

Uridine phosphorylase      

Location in the cell

Cytoplasmic   Reliability : 3.561

CDS

ATGTCATTCGATAACGACGAGCTACGTGACGAATACCCAGATGGCACTGTCCGATTGCGTAACCCTAACATTGAACTCATGGACCAAGATATTCTCTACCATTTGGCCCTTGGGAGCGGCTCCCATGATCTTGTTGAGATGTTTGGAGACGTCAAGTTTGTGTGCATGGGCGGAACACCGAAACGCATGGAACAATTCGCATACACAATCATGGCGGAGATAGGGCACAAGTTGCCTTGTGGAACTACACTGCAAGACATCAGTCATTTTTCTTACAGATACTCCATGTATAAAGTTGGCCCGGTACTTTCTATAAGTCACGGTATGGGCATACCTTCTGTCGGAATCCTGCTTCACGAAGTCATAAAGTTGATGTACCACGCGAAAGTCCGTGATCCTGTGTTCTTCAGAATCGGAACATGTGGTGGTATAGGCTACGAAGGCGGTACGGTTGTTATTTCCGATGAAGCCGTCGATGGAGCCCTGAGGAATGTTCTAGAACTGACAGTTTTAGGAAAAATAGTTCAGCGTCCAGCGAAACTGGATCGGCGATTAGTTAGGGAGCTGAAAGCACTGGCCGATCCCGAAGACCCCTACGACACCGTGACCGGCAAAACAATGTGCACGTACGATTTCTATGAAGGACAAGGTCGTTTAGATGGTGCCTTTTGTGATTTCACCGAAACTGATAAGATGGAGTACTTAGAGAGCATCCACAAAGCCGGCGTTGTTAACATTGAGATGGAGTCCCTCTCTTTCGCCGCCCTCACTCATCACGCGGGCATTAAGGCAGCTGTCGTCTGCGTTACTGTTTTAGACAGATTGAAGGGTGATCAGGTTTTAGCTCCTAAAGAAGTTTTGGATGAGTGGCAACAGCGTCCCACGAAGCTTGTTTGCCGTTACATTAAAAGGTATCTTCAGGTGAAGGGAAAAATCTCTTTAGATGGTCACGGTTCCATTGCCGTGAAGAGTCCCCGTCGATTCAAGCTTGTGCAGCAGGAATCTGAGACATATGATTAA

Protein

MSFDNDELRDEYPDGTVRLRNPNIELMDQDILYHLALGSGSHDLVEMFGDVKFVCMGGTPKRMEQFAYTIMAEIGHKLPCGTTLQDISHFSYRYSMYKVGPVLSISHGMGIPSVGILLHEVIKLMYHAKVRDPVFFRIGTCGGIGYEGGTVVISDEAVDGALRNVLELTVLGKIVQRPAKLDRRLVRELKALADPEDPYDTVTGKTMCTYDFYEGQGRLDGAFCDFTETDKMEYLESIHKAGVVNIEMESLSFAALTHHAGIKAAVVCVTVLDRLKGDQVLAPKEVLDEWQQRPTKLVCRYIKRYLQVKGKISLDGHGSIAVKSPRRFKLVQQESETYD

Description

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Catalytic Activity

phosphate + uridine = alpha-D-ribose 1-phosphate + uracil

Similarity

Belongs to the PNP/UDP phosphorylase family.

Uniprot

H9JM89   A0A2A4K1Z2   A0A2H1V6R5   A0A212FID5   A0A2J7QZT9   A0A2J7QZT7   + More
V9IDR4   A0A087ZWP1   E0VS64   A0A2A3E7V8   A0A154PIC4   A0A310SL28   A0A1B6DDL4   A0A1B6E436   E2BQK2   A0A1B6HN66   A0A1B6KFU3   A0A0M9A7T4   D6WB44   A0A1B6F7G6   A0A146L6D1   A0A0A9Z8J9   A0A1B6HJ75   A0A1Y1KPY8   A0A146LJI9   A0A0K8TEY3   A0A3L8DUK8   A0A0C9RSZ0   A0A0K8TFY7   A0A0A9W2Y6   T1HDV8   A0A023F5G7   A0A0J7NMJ0   A0A2R7WS35   V5GTE6   V5GHK9   A0A069DYM6   A0A0L7RE46   V9IBJ4   A0A151I7F7   K7IX67   A0A195DTR6   A0A026X308   A0A195EX43   A0A195BKF7   A0A158P1D5   A0A067QX58   A0A232F8R8   A0A2C9GJV1   A0A182U4M6   A0A0T6B3J4   E9IS52   A0A084VNU7   A0A182J5Y0   A0A1B0CE83   A0A182X800   Q7PFX7   A0A182P2A8   A0A182HIB7   A0A182VAL4   A0A182YQ65   A0A182K465   A0A2S2NMA6   A0A182MVH1   A0A151XGU5   A0A182N1K9   A0A182QKN0   A0A182R7I4   A0A2S2QKU5   A0A182W501   B0X890   J9K4G6   A0A1Q3FZS6   F4X7J5   A0A1Q3G579   A0A1L8DXV7   N6TC60   A0A336KHJ2   A0A336M4H0   A0A336KKR0   A0A023EQI1   Q178N8   A0A1S4FC12   B4PSB2   B4LX04   B4QWT9   B4IC10   A0A1I8PMF4   A0A0Q9XCR7   A0A1W4V8P5   U5ET54   Q8IMQ8   A0A194PIH8   A0A0P8YNJ8   B4JRW5   A0A034VL97   A0A0K8W9L3   A0A0Q9WSV4   A0A0K8VVM9   A0A1I8PMD6  

EC Number

2.4.2.3

Pubmed

19121390    22118469    20566863    20798317    18362917    19820115    + More
26823975    25401762    28004739    30249741    25474469    26334808    20075255    24508170    21347285    24845553    28648823    21282665    24438588    12364791    14747013    17210077    25244985    21719571    23537049    24945155    17510324    17994087    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    26354079    25348373   

EMBL

BABH01033344    BABH01033345    BABH01033346    NWSH01000241    PCG78079.1    ODYU01000777    + More
SOQ36082.1    AGBW02008396    OWR53503.1    NEVH01009067    PNF34098.1    PNF34097.1    JR038970    AEY58469.1    DS235745    EEB16220.1    KZ288354    PBC27269.1    KQ434924    KZC11562.1    KQ763442    OAD55085.1    GEDC01028640    GEDC01013514    GEDC01006288    GEDC01002289    JAS08658.1    JAS23784.1    JAS31010.1    JAS35009.1    GEDC01022789    GEDC01020497    GEDC01005374    GEDC01004624    JAS14509.1    JAS16801.1    JAS31924.1    JAS32674.1    GL449769    EFN82060.1    GECU01031587    JAS76119.1    GEBQ01029650    JAT10327.1    KQ435729    KOX77619.1    KQ971311    EEZ98936.1    GECZ01023698    JAS46071.1    GDHC01014625    JAQ04004.1    GBHO01037693    GBHO01002022    GBRD01009849    JAG05911.1    JAG41582.1    JAG55975.1    GECU01033004    JAS74702.1    GEZM01080281    JAV62230.1    GDHC01010451    JAQ08178.1    GBRD01001777    JAG64044.1    QOIP01000004    RLU24155.1    GBYB01011750    JAG81517.1    GBRD01001776    GDHC01018041    JAG64045.1    JAQ00588.1    GBHO01044384    GBHO01037687    JAF99219.1    JAG05917.1    ACPB03023190    GBBI01002313    JAC16399.1    LBMM01003297    KMQ93695.1    KK855399    PTY22378.1    GALX01004968    JAB63498.1    GALX01004967    JAB63499.1    GBGD01002125    JAC86764.1    KQ414612    KOC69104.1    JR038971    AEY58470.1    KQ978415    KYM94074.1    AAZX01000598    KQ980390    KYN16256.1    KK107046    EZA61784.1    KQ981928    KYN32850.1    KQ976449    KYM85808.1    ADTU01006324    ADTU01006325    ADTU01006326    KK852865    KDR14775.1    NNAY01000643    OXU27234.1    APCN01003925    LJIG01015983    KRT81967.1    GL765283    EFZ16663.1    ATLV01014923    KE524996    KFB39641.1    AJWK01008658    AAAB01008846    EAA45146.4    GGMR01005686    MBY18305.1    AXCM01001441    KQ982138    KYQ59624.1    AXCN02002448    GGMS01009141    MBY78344.1    DS232478    EDS42359.1    ABLF02040899    ABLF02040913    GFDL01001988    JAV33057.1    GL888851    EGI57572.1    GFDL01000083    JAV34962.1    GFDF01002862    JAV11222.1    APGK01043564    KB741015    ENN75323.1    UFQS01000433    UFQT01000433    SSX03877.1    SSX24242.1    SSX03876.1    SSX24241.1    SSX03875.1    SSX24240.1    GAPW01001751    JAC11847.1    CH477361    EAT42652.1    CM000160    EDW98574.1    CH940650    EDW67751.1    CM000364    EDX14606.1    CH480828    EDW45168.1    CH933806    KRG02161.1    GANO01002923    JAB56948.1    AE014297    BT099788    AAN14095.1    ACV91625.1    KQ459603    KPI92853.1    CH902617    KPU80335.1    CH916373    EDV94505.1    GAKP01016644    JAC42308.1    GDHF01027907    GDHF01004431    JAI24407.1    JAI47883.1    CH964232    KRF99317.1    GDHF01009385    JAI42929.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000235965    UP000005203    UP000009046    + More
UP000242457    UP000076502    UP000008237    UP000053105    UP000007266    UP000279307    UP000015103    UP000036403    UP000053825    UP000078542    UP000002358    UP000078492    UP000053097    UP000078541    UP000078540    UP000005205    UP000027135    UP000215335    UP000075840    UP000075902    UP000030765    UP000075880    UP000092461    UP000076407    UP000007062    UP000075885    UP000075903    UP000076408    UP000075881    UP000075883    UP000075809    UP000075884    UP000075886    UP000075900    UP000075920    UP000002320    UP000007819    UP000007755    UP000019118    UP000008820    UP000002282    UP000008792    UP000000304    UP000001292    UP000095300    UP000009192    UP000192221    UP000000803    UP000053268    UP000007801    UP000001070    UP000007798   

PRIDE

H9JM89    Q8IMQ8   

Pfam

PF01048   PNP_UDP_1

Interpro

IPR010059   Uridine_phosphorylase_euk        + More
IPR035994   Nucleoside_phosphorylase_sf       
IPR000845   Nucleoside_phosphorylase_d       
IPR017893   DBB_domain       
IPR018016   Nucleoside_phosphorylase_CS       

SUPFAM

SSF53167   SSF53167       

Gene 3D

3.40.50.1580    

ProteinModelPortal

H9JM89   A0A2A4K1Z2   A0A2H1V6R5   A0A212FID5   A0A2J7QZT9   A0A2J7QZT7   + More
V9IDR4   A0A087ZWP1   E0VS64   A0A2A3E7V8   A0A154PIC4   A0A310SL28   A0A1B6DDL4   A0A1B6E436   E2BQK2   A0A1B6HN66   A0A1B6KFU3   A0A0M9A7T4   D6WB44   A0A1B6F7G6   A0A146L6D1   A0A0A9Z8J9   A0A1B6HJ75   A0A1Y1KPY8   A0A146LJI9   A0A0K8TEY3   A0A3L8DUK8   A0A0C9RSZ0   A0A0K8TFY7   A0A0A9W2Y6   T1HDV8   A0A023F5G7   A0A0J7NMJ0   A0A2R7WS35   V5GTE6   V5GHK9   A0A069DYM6   A0A0L7RE46   V9IBJ4   A0A151I7F7   K7IX67   A0A195DTR6   A0A026X308   A0A195EX43   A0A195BKF7   A0A158P1D5   A0A067QX58   A0A232F8R8   A0A2C9GJV1   A0A182U4M6   A0A0T6B3J4   E9IS52   A0A084VNU7   A0A182J5Y0   A0A1B0CE83   A0A182X800   Q7PFX7   A0A182P2A8   A0A182HIB7   A0A182VAL4   A0A182YQ65   A0A182K465   A0A2S2NMA6   A0A182MVH1   A0A151XGU5   A0A182N1K9   A0A182QKN0   A0A182R7I4   A0A2S2QKU5   A0A182W501   B0X890   J9K4G6   A0A1Q3FZS6   F4X7J5   A0A1Q3G579   A0A1L8DXV7   N6TC60   A0A336KHJ2   A0A336M4H0   A0A336KKR0   A0A023EQI1   Q178N8   A0A1S4FC12   B4PSB2   B4LX04   B4QWT9   B4IC10   A0A1I8PMF4   A0A0Q9XCR7   A0A1W4V8P5   U5ET54   Q8IMQ8   A0A194PIH8   A0A0P8YNJ8   B4JRW5   A0A034VL97   A0A0K8W9L3   A0A0Q9WSV4   A0A0K8VVM9   A0A1I8PMD6  

PDB

3NBQ     E-value=2.25738e-80,     Score=760

KEGG

101736970    K00757 uridine phosphorylase [EC:2.4.2.3] | (RefSeq) uridine phosphorylase 1

PATHWAY

00240    Pyrimidine metabolism - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0004850   GO:0009116   GO:0009166   GO:0005737   GO:0044206   GO:0042332   GO:0003824   GO:0007156   GO:0008237   GO:0043401   GO:0003707   GO:0051537  

Length:

339

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

3.33191

Exp number, first 60 AAs:

0.00494

Total prob of N-in:

0.10809

outside

1  -  339

 

 

Pi

20.668271

Theta

19.553042

Tajima's D

0.034226

CLR

0.940158

CSRT

0.376331183440828

Interpretation

Uncertain