Gene

KWMTBOMO07254

Pre Gene Modal

BGIBMGA010590

Annotation

protease_[Helicoverpa_armigera]

Location

Bomo_Chr12(+):9152701-9156358      View in EpiBrowser

Full name

Trypsin, alkaline C       + More
Trypsin, alkaline A      
Trypsin, alkaline B      
Trypsin CFT-1      

Location in the cell

Extracellular   Reliability : 2.834

CDS

ATGGAGACTTGTGTGTTACCCCATGTGGTCCTGTATGCACAGAGAATCGGTACAAAATTCCATTTGATGCATGATAATGCTCGCGCTCATAAAGCTAGGGCTACCAGAGAGGCTCTAGAGAAGGCTGGTTGGTATACAGATGTTGCCCTGGCCCAGAGTCCGGACCTAAATCTCATGGGAAACATGTGGGATTCACTGTCGGTGCCAAGAAGTGTCACACGTATCGTGGGTGGTTCTCCTACAACGGTGGAGACGTATCCTTACATGGCAAACATGCAGTTCCTCTGGTGGGGTGTTTTTTGGGGACTGGGTTGTGGCGGATCTCTCGTTACAAGAAACACTGTCGTCTCCGCTTCCCATTGTTTCATTGGCGATCGTCCTAGTCAGTGGCGTGTTCTACTCGGAACCTCTCTGGCTTCATCGGGTGGTACCACCCACGCTGTGAGAGAAATTGTCCTGCATCCACAGTACATTCACCGAACTCTTGACAACGATATTGCTATCATTCGGTTGTCCAACCCCGCCGTTTATTCGAGCAGTATCCAGCCTGTTCGTATCGCAGGAGCTAACTATAATGTTCCCGATGGTGCCGTGGTCACTGCTATCGGATGGGGAGCTCTCTCGCATGGCGGCCCATCTCCTCAGCAACTGCAGCATGTGGATGTAAATATCATCAACCATCAACTCTGCGTGGAACGTTACGCTTTCTTGAAGACTCGGCCCGGTTTCGAAAACTGGCCAGATATCACTGAGAACATGTTATGCGCTGGTATCCTCAACGTCGGAGGCAAGGACGCCTGCCAAGGTGACTCCGGTGGCCCCCTCGCTCACCAAGGAGACATTCTTGTCGGTGTCACCTCCTGGGGCTACAGATGTGCCGATCCTTTCTATCCCGGAGTCAACGCTCGCGTTTCCCGCTTCACCGACTGGATAGCAACCAACGCTTAA

Protein

METCVLPHVVLYAQRIGTKFHLMHDNARAHKARATREALEKAGWYTDVALAQSPDLNLMGNMWDSLSVPRSVTRIVGGSPTTVETYPYMANMQFLWWGVFWGLGCGGSLVTRNTVVSASHCFIGDRPSQWRVLLGTSLASSGGTTHAVREIVLHPQYIHRTLDNDIAIIRLSNPAVYSSSIQPVRIAGANYNVPDGAVVTAIGWGALSHGGPSPQQLQHVDVNIINHQLCVERYAFLKTRPGFENWPDITENMLCAGILNVGGKDACQGDSGGPLAHQGDILVGVTSWGYRCADPFYPGVNARVSRFTDWIATNA

Catalytic Activity

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

Similarity

Belongs to the peptidase S1 family.

Keywords

Disulfide bond   Hydrolase   Protease   Secreted   Serine protease   Signal   Zymogen   Direct protein sequencing  

Feature

propeptide  Activation peptide
chain  Trypsin, alkaline C

Uniprot

H9JM38   A0A2H1VG89   B1NLD9   A0A2W1C1W9   C9W8I2   I7D523   + More
A0A2A4JCA8   A0A089QDB3   A0A2H1V951   Q9NB92   A0A2H1VAT0   Q4L1K1   A0A1E1WAD4   A0A2W1BUQ8   Q9NB91   A0A2W1BSQ0   I7DHM0   E7D014   A0A2H1V654   A0A2A4JT25   A0A2H1WTV1   E7D012   I7CHH2   C9W8H2   S5PZA0   A0A212EJA7   A0A212F0R1   A0A212FJI9   A0A2U8NFD7   A0A194PNR6   Q56IB6   Q56IB8   Q961Y0   Q6R561   Q56IB4   Q56IB5   A0A2A4K747   A0A194PQQ5   Q56IB7   A0A194PNR3   H9J230   A0A0N1PHJ0   A0A2W1BKF9   A0A194PQ27   P35047   P35045   P35046   Q27540   H9J231   I3UII6   P35042   H9J229   A0A2W1B1G1   A0A194PP33   A0A2H1VJ41   A0A3S2TNU2   A0A0N1I947   J7JYV8   I6TMW8   T1QDI0   Q9TXE6   A0A194PQQ0   V9LL27   S5PVP1   A0A194PVB6   G9F9K6   E7D004   A0A1E1WDA8   H9J243   A0A2A4K5G7   B4X995   Q4L1K4   A0A2A4K6E9   J7IJ83   A0A2W1BB90   C9W8F7   A0A2A4K648   A0A2A4K5I4   B4X996   A0A2A4K6U2   V9M0R7   A0A2W1BA14   A0A1C9M3A1   O62598   B4X9A1   A0A2A4K6E3   O18447   Q4L1M0   O76954   A0A2A4K5F8  

EC Number

3.4.21.4

Pubmed

19121390    18314941    28756777    20824821    22824002    11267903    + More
15979001    23606528    22118469    26354079    16469064    12110299    15944081    8205142    7550246    22432944    8294037    8353523    23955944    8462672    23247047    10672067    9404008   

EMBL

BABH01005843    ODYU01002419    SOQ39873.1    EF600054    ABU98619.1    KZ149911    + More
PZC78103.1    FJ205428    ACR15995.1    JN793545    AFO68325.1    NWSH01002022    PCG69396.1    KM083787    AIR09768.1    ODYU01001303    SOQ37326.1    AF261970    AAF74732.1    SOQ37324.1    AY587164    AAT95356.1    GDQN01007155    JAT83899.1    PZC78101.1    AF261971    AF261990    AAF74733.1    PZC78102.1    JN793547    AFO68327.1    HM990184    ADT80832.1    ODYU01000875    SOQ36297.1    NWSH01000723    PCG74613.1    ODYU01011017    SOQ56495.1    HM990182    ADT80830.1    JN793546    AFO68326.1    FJ205417    ACR15985.2    KC175565    AGR92347.1    AGBW02014494    OWR41582.1    AGBW02011038    OWR47339.1    AGBW02008255    OWR53908.1    MF407317    AWL83213.1    KQ459597    KPI95071.1    AY953061    AAX62034.1    AY953059    AAX62032.1    AY040819    AAK81696.1    AY513649    AAR98918.1    AY953063    AAX62036.1    AY953062    AAX62035.1    NWSH01000106    PCG79472.1    KPI95074.1    AY953060    AAX62033.1    KPI95066.1    BABH01007517    KQ460226    KPJ16473.1    KZ149992    PZC75529.1    KPI95068.1    L16807    L16805    L16806    U12917    AAA84423.1    BABH01007514    BABH01007515    JN315760    AFK64824.1    L04749    BABH01007520    KZ150747    PZC70338.1    KPI95067.1    ODYU01002655    SOQ40442.1    RSAL01000038    RVE51123.1    KPJ16474.1    JX312360    AFQ59994.1    JQ904123    AFM77753.1    JQ429438    AFW03963.1    KPI95069.1    JQ340915    AFP74111.1    KC175562    AGR92345.1    KPI95070.1    JN033751    JN315765    AEW46904.1    AFK64829.1    HM990174    ADT80822.1    GDQN01010607    GDQN01006137    JAT80447.1    JAT84917.1    BABH01007473    PCG79485.1    EF531631    EF531633    ABR88242.1    ABR88244.1    AY587161    AAT95353.1    PCG79488.1    JX195651    AFQ37934.1    PZC70336.1    FJ205402    ACR15970.1    PCG79486.1    PCG79487.1    EF531632    ABR88243.1    PCG79473.1    JX866720    AGB93875.1    PZC70337.1    KU302250    AOQ30448.1    AF064525    AF064526    AAC36247.1    AAC36248.1    EF531637    ABR88248.1    PCG79474.1    HM209426    Y12283    KZ150104    ADI32887.1    CAA72962.1    PZC73444.1    AY587145    AAT95360.1    AJ007706    CAA07611.1    PCG79475.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000053268    UP000053240    UP000283053    + More

PRIDE

H9JM38    H9J230    P35047    P35045    H9J231    P35042    + More
H9J229    J7JYV8    Q9TXE6    H9J243   

Pfam

PF00089   Trypsin

Interpro

IPR001314   Peptidase_S1A        + More
IPR009003   Peptidase_S1_PA       
IPR001254   Trypsin_dom       
IPR018114   TRYPSIN_HIS       
IPR033116   TRYPSIN_SER       

SUPFAM

SSF50494   SSF50494       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9JM38   A0A2H1VG89   B1NLD9   A0A2W1C1W9   C9W8I2   I7D523   + More
A0A2A4JCA8   A0A089QDB3   A0A2H1V951   Q9NB92   A0A2H1VAT0   Q4L1K1   A0A1E1WAD4   A0A2W1BUQ8   Q9NB91   A0A2W1BSQ0   I7DHM0   E7D014   A0A2H1V654   A0A2A4JT25   A0A2H1WTV1   E7D012   I7CHH2   C9W8H2   S5PZA0   A0A212EJA7   A0A212F0R1   A0A212FJI9   A0A2U8NFD7   A0A194PNR6   Q56IB6   Q56IB8   Q961Y0   Q6R561   Q56IB4   Q56IB5   A0A2A4K747   A0A194PQQ5   Q56IB7   A0A194PNR3   H9J230   A0A0N1PHJ0   A0A2W1BKF9   A0A194PQ27   P35047   P35045   P35046   Q27540   H9J231   I3UII6   P35042   H9J229   A0A2W1B1G1   A0A194PP33   A0A2H1VJ41   A0A3S2TNU2   A0A0N1I947   J7JYV8   I6TMW8   T1QDI0   Q9TXE6   A0A194PQQ0   V9LL27   S5PVP1   A0A194PVB6   G9F9K6   E7D004   A0A1E1WDA8   H9J243   A0A2A4K5G7   B4X995   Q4L1K4   A0A2A4K6E9   J7IJ83   A0A2W1BB90   C9W8F7   A0A2A4K648   A0A2A4K5I4   B4X996   A0A2A4K6U2   V9M0R7   A0A2W1BA14   A0A1C9M3A1   O62598   B4X9A1   A0A2A4K6E3   O18447   Q4L1M0   O76954   A0A2A4K5F8  

PDB

1EKB     E-value=4.88835e-40,     Score=412

KEGG

101736414    no KO assigned | (RefSeq) trypsin, alkaline C-like

GO

GO:0004252   GO:0005615   GO:0008236   GO:0006508   GO:0004645   GO:0030170   GO:0006520   GO:0008237   GO:0043401   GO:0003707   GO:0051537  

Subcellular location

  

Length:

315

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

7.32053999999999

Exp number, first 60 AAs:

0.01823

Total prob of N-in:

0.17289

outside

1  -  315

 

 

Pi

4.423279

Theta

8.41248

Tajima's D

-1.473335

CLR

1.326427

CSRT

0.0607969601519924

Interpretation

Uncertain