Gene

KWMTBOMO07245  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010365

Annotation

uncharacterized_protein_LOC692518_[Bombyx_mori]

Location

Bomo_Chr12(-):8996049-9000959      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 2.16

CDS

ATGGCGCCCAATGTAAAGGATGCAAATGGTGTTCTCTTTGAAAATGATGCTGATACTCCAGACTTAGGACTGTCCAGCACACCTGTACAGCAAGCCGACAACTACCCAAAGAAACTAGTTTGGAGGAATATAATACTTTTTACATACCTTCATATTGCTGCGTTGTATGGAGGCTACCTTTTCTTATTTCATGCGAAATGGCAAACAGACCTATTTGCCTATATATTGTATGTAATGTCAGGACTTGGCATCACAGCAGGTGCACATAGATTATGGGCACATAAATCATACAAAGCAAAGTGGCCTCTACGTGTTATCCTTATCATCTTCAATTCCTTGGCTTTTCAGGATTCTGCTTTAGATTGGGCACGTGATCATCGCATGCATCATAAATACTCCGAGACTGATGCCGACCCACATAATGCCACACGAGGTTTCTTTTTCTCTCACATTGGCTGGCTTCTAGTGAGGAAACATCCAGAACTGAAGAGAAAGGGCAAGGGTCTCGACCTAAGTGACTTATATGCTGATCCCATTCTTCGATTCCAGAAAAAGTACTATTTAATTCTGATGCCAATCGCTTGCTTCATTTTGCCAACAGTGATTCCGGTGTATTTTTGGAATGAGTCTTGGATTAACGCGTTCTTCGTTGCGACTCTTTTCCGTTATACATTTATTTTGAATGTCACATGGCTAGTGAACTCCGCTGCTCACAAATGGGGTGGAAAACCCTACGACAAGAATATCAAGCCATCCGAGAACATCTCCGTGTCGGTGTTTGCACTCGGCGAGGGATTCCACAACTACCACCACACATTCCCATGGGACTACAAGACAGCGGAACTCGGTAACAACAGATTAAACTTCACCACCAATTTCATCAATTTCTTTGCTAAAATTGGATGGGCATACGATTTGAAAACTGTATCTGACGAGATCATAAAGAACCGTGTGAACCGCACCGGTGATGGCTCTCACTACCTCTGGGGCTGGGGCGATAAAGATCTGGACAAAGAGGAAATAAAGCAAGCCATCCGCATCAATCCTAAGGACAATTGA

Protein

MAPNVKDANGVLFENDADTPDLGLSSTPVQQADNYPKKLVWRNIILFTYLHIAALYGGYLFLFHAKWQTDLFAYILYVMSGLGITAGAHRLWAHKSYKAKWPLRVILIIFNSLAFQDSALDWARDHRMHHKYSETDADPHNATRGFFFSHIGWLLVRKHPELKRKGKGLDLSDLYADPILRFQKKYYLILMPIACFILPTVIPVYFWNESWINAFFVATLFRYTFILNVTWLVNSAAHKWGGKPYDKNIKPSENISVSVFALGEGFHNYHHTFPWDYKTAELGNNRLNFTTNFINFFAKIGWAYDLKTVSDEIIKNRVNRTGDGSHYLWGWGDKDLDKEEIKQAIRINPKDN

Cofactor

Fe cation

Similarity

Belongs to the fatty acid desaturase type 1 family.

Uniprot

I3QPX9   Q75PL6   H9JLG4   Q4A182   S4PEM6   A0A212FG51   + More
A0A194R0B7   A0A194PHD4   B7SB75   Q7K403   Q9NGQ7   B7SB77   B7SB76   A0A0M3L9S4   A0A1E1VYJ4   D8UUT5   Q9NB25   A0A0U2F3B9   A0A291P0G3   Q8WQQ0   Q8ITE5   Q8ITE4   T1RTF5   Q8ITE8   A0A0U2F3B3   Q8MZZ4   T1RTD3   E3TMV0   A0A2H1V8Q0   A0A1L8D6B6   U5KFT8   A9YRX5   I7B370   A0A0P0EGH8   Q9NGQ8   A9ZSZ7   G8FQ63   A0A076FR53   G8FQ64   Q6US82   Q9NG28   G8FQ62   B6CBS2   A0A0L7LB21   A0A1A9Z238   D3TP66   A0A1A9WBD6   A0A182QY62   A0A182MQV9   A0A182PSJ2   A0A182Y3S6   A0A2M3YY30   A0A182VZL7   A0A2M4AGB5   A0A182FAQ2   A0A2M4BT31   W5J215   A0A182NRU1   B4QSA3   B3M2R7   A0A182RZM3   A0A2M3YY13   Q9U972   Q7K4Y0   Q94541   A0A182K5W6   A0A182UTT3   A0A182WSS9   A0A182LA27   F5HMH9   A0A182HLN2   B4PPA5   T1DNF2   Q9U967   B4GZ70   A0A182IX38   A6P6Z1   Q29B20   A0A1I8NWA7   A0A023EPC8   A0A0K8TSL7   Q17G31   Q8ITN6   T1PCA2   W6ACM3   B3P4B3   A0A1L8EEG9   B0X4F1   A0A084W6J7   B4JRQ4   B4M0C1   A0A1A9WBD7   B4K744   T1PL97   A0A0M4EPW0   T1E253   A0A1Q3FJ73   A0A1E1WUE8   A0A1B0CEY2   A0A336M2F9  

Pubmed

19121390    23622113    22118469    26354079    20403437    12237399    + More
11483431    28986331    28756777    11805319    15527989    24500170    15455060    12524345    12770579    20691782    24053512    18405835    26445454    24211206    22291612    24817326    15544945    12213232    18831750    26227816    20353571    25244985    20920257    23761445    17994087    18057021    10920187    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    9501419    20966253    12364791    14747013    17210077    17550304    17916502    15632085    23185243    24945155    26369729    17510324    12421411    25315136    24438588    24330624   

EMBL

JQ729998    AFK13830.1    JQ729997    AB166852    AFK13829.1    BAD18123.1    + More
BABH01005826    AM076338    CAJ27975.1    GAIX01006995    JAA85565.1    AGBW02008720    OWR52703.1    KQ460883    KPJ11142.1    KQ459603    KPI92821.1    EU152401    ABX71810.1    AY057862    AAL27033.1    AF243047    AAF44710.1    EU152403    ABX71812.1    EU152402    ABX71811.1    KM366791    AIM40221.1    GDQN01011259    GDQN01009722    GDQN01007857    JAT79795.1    JAT81332.1    JAT83197.1    GQ225747    GQ225749    ADE58520.1    AF272343    AAF81788.1    KP008120    MF687582    AKU76407.1    ATJ44508.1    MF687527    KZ149911    ATJ44453.1    PZC78117.1    AY061988    AAL35750.1    AF518020    AAN39700.1    AF518021    AAN39701.1    JX531653    NWSH01001519    AGO45838.1    PCG70996.1    AF518017    AAN39697.1    KP008113    AKU76400.1    AF482906    AAM28481.2    JX531660    AGO45845.1    GU952765    ADO85598.1    ODYU01001259    SOQ37220.1    GEYN01000137    JAV01992.1    JX989152    AGR49311.1    EU285579    ABX90048.1    JX126483    AFO38464.1    KT261693    ALJ30233.1    AF243046    AAF44709.1    AB373031    BAF97042.1    JN022473    AER29842.1    KF960740    AII21942.1    JN022474    JN022475    AER29843.1    AY362878    AAQ74258.1    AF268275    JN022476    AAF73073.1    AER29845.1    JN022472    AER29841.1    EU152332    ABX71627.1    JTDY01001896    KOB72605.1    CCAG010012100    EZ423218    ADD19494.1    AXCN02001148    AXCM01000026    GGFM01000428    MBW21179.1    GGFK01006347    MBW39668.1    GGFJ01006787    MBW55928.1    ADMH02002143    ETN58292.1    CM000364    EDX13199.1    CH902617    EDV42388.1    KPU79686.1    KPU79687.1    GGFM01000421    MBW21172.1    AJ245747    CAB52474.1    AE014297    AY051593    AAF54819.1    AAF54820.1    AAF54821.1    AAF54822.1    AAK93017.1    AAN13544.1    U73160    AAB17283.1    AAAB01008987    EAA43119.4    EGK97500.1    EGK97501.1    EGK97502.1    APCN01000909    CM000160    EDW97111.1    KRK03534.1    GAMD01002940    JAA98650.1    AJ245748    CAB52475.1    CH479198    EDW28088.1    AB300221    BAF69118.1    CM000070    EAL27178.1    KRS99817.1    GAPW01002266    JAC11332.1    GDAI01000236    JAI17367.1    CH477266    EAT45554.1    EAT45555.1    AF417841    AAN31393.1    KA646397    AFP61026.1    KF835695    AHI54575.1    CH954181    EDV49358.1    GFDG01001755    JAV17044.1    DS232338    EDS40304.1    ATLV01020821    KE525308    KFB45841.1    CH916373    EDV94444.1    CH940650    EDW67283.1    KRF83228.1    CH933806    EDW16357.1    KRG02060.1    KRG02061.1    KA649511    KA649512    AFP64140.1    CP012526    ALC47890.1    GALA01001044    JAA93808.1    GFDL01007467    JAV27578.1    GDQN01000462    JAT90592.1    AJWK01009463    UFQT01000109    SSX20158.1   

Proteomes

UP000005204    UP000007151    UP000053240    UP000053268    UP000218220    UP000037510    + More
UP000092445    UP000092444    UP000091820    UP000075886    UP000075883    UP000075885    UP000076408    UP000075920    UP000069272    UP000000673    UP000075884    UP000000304    UP000007801    UP000075900    UP000000803    UP000075881    UP000075903    UP000076407    UP000075882    UP000007062    UP000075840    UP000002282    UP000008744    UP000075880    UP000001819    UP000095300    UP000008820    UP000095301    UP000008711    UP000002320    UP000030765    UP000001070    UP000008792    UP000009192    UP000092553    UP000092461   

PRIDE

Q75PL6    H9JLG4    Q9U972    Q7K4Y0    Q94541   

Pfam

PF00487   FA_desaturase

Interpro

IPR005804   FA_desaturase_dom        + More
IPR001522   FADS-1_CS       
IPR015876   Acyl-CoA_DS       
IPR009160   Acyl-CoA_deSatase_haem/ster-bd       

CDD

cd03505  Delta9-FADS-like

ProteinModelPortal

I3QPX9   Q75PL6   H9JLG4   Q4A182   S4PEM6   A0A212FG51   + More
A0A194R0B7   A0A194PHD4   B7SB75   Q7K403   Q9NGQ7   B7SB77   B7SB76   A0A0M3L9S4   A0A1E1VYJ4   D8UUT5   Q9NB25   A0A0U2F3B9   A0A291P0G3   Q8WQQ0   Q8ITE5   Q8ITE4   T1RTF5   Q8ITE8   A0A0U2F3B3   Q8MZZ4   T1RTD3   E3TMV0   A0A2H1V8Q0   A0A1L8D6B6   U5KFT8   A9YRX5   I7B370   A0A0P0EGH8   Q9NGQ8   A9ZSZ7   G8FQ63   A0A076FR53   G8FQ64   Q6US82   Q9NG28   G8FQ62   B6CBS2   A0A0L7LB21   A0A1A9Z238   D3TP66   A0A1A9WBD6   A0A182QY62   A0A182MQV9   A0A182PSJ2   A0A182Y3S6   A0A2M3YY30   A0A182VZL7   A0A2M4AGB5   A0A182FAQ2   A0A2M4BT31   W5J215   A0A182NRU1   B4QSA3   B3M2R7   A0A182RZM3   A0A2M3YY13   Q9U972   Q7K4Y0   Q94541   A0A182K5W6   A0A182UTT3   A0A182WSS9   A0A182LA27   F5HMH9   A0A182HLN2   B4PPA5   T1DNF2   Q9U967   B4GZ70   A0A182IX38   A6P6Z1   Q29B20   A0A1I8NWA7   A0A023EPC8   A0A0K8TSL7   Q17G31   Q8ITN6   T1PCA2   W6ACM3   B3P4B3   A0A1L8EEG9   B0X4F1   A0A084W6J7   B4JRQ4   B4M0C1   A0A1A9WBD7   B4K744   T1PL97   A0A0M4EPW0   T1E253   A0A1Q3FJ73   A0A1E1WUE8   A0A1B0CEY2   A0A336M2F9  

PDB

4YMK     E-value=6.29955e-97,     Score=903

KEGG

692518    K00507 stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1] | (RefSeq) DESAT4; fatty acid des

PATHWAY

01040    Biosynthesis of unsaturated fatty acids - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)
01212    Fatty acid metabolism - Bombyx mori (domestic silkworm)

GO

GO:0016717   GO:0016021   GO:0006633   GO:0004768   GO:0042593   GO:0040018   GO:0005783   GO:0019216   GO:0048047   GO:0006636   GO:0031410   GO:0045793   GO:0010506   GO:0006723   GO:0042594   GO:0045572   GO:0009744   GO:0070328   GO:0060179   GO:0042811   GO:0005506   GO:0005789   GO:0006629   GO:0003676   GO:0008270   GO:0006520   GO:0006508   GO:0008237   GO:0043401   GO:0003707   GO:0051537   GO:0055114  

PANTHER

PTHR11351  

Length:

352

Number of predicted TMHs:

4

Exp number of AAs in TMHs:

91.5661600000001

Exp number, first 60 AAs:

20.78937

Total prob of N-in:

0.95393

POSSIBLE N-term signal

sequence

inside

1  -  38

TMhelix

39  -  61

outside

62  -  70

TMhelix

71  -  93

inside

94  -  184

TMhelix

185  -  207

outside

208  -  210

TMhelix

211  -  233

inside

234  -  352

 

 

Pi

0.229116

Theta

1.472672

Tajima's D

-1.823006

CLR

439.390715

CSRT

0.0167991600419979

Interpretation

Possibly Positive selection