Gene

KWMTBOMO07244  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010586

Annotation

hypothetical_protein_KGM_20562_[Danaus_plexippus]

Location

Bomo_Chr12(+):8981850-8991086      View in EpiBrowser

Full name

Palmitoyltransferase      

Location in the cell

PlasmaMembrane   Reliability : 2.808

CDS

ATGTCGGAATCGTGTCAGGACGGTAATTGTCAAGGAAATAATGAATATGGACCTGAAGAATCGCCTACCAAACTCATTGTCAATTACATTCCTGAAGTCATGACCCAGGATATGATGTTTTCTTTATTTTCAACAATGGGCAAATTGGAGAGTTGTAAGTTGATAGCAAATCGAGGCTATGGATTCGTCGAGTACACACGTCCGGACGATGCAGTTAAAGCTCGTAAAGCGTTCAACGGTCTACTGATGCAGAATAAGACTCTCAAAGTGTCACACGCATTACTTAATCCAGAACTTAAGCCACCAACAAAACCTGAAGCCGACTGGAATCTCTACATTTGTAACCTACCTAATGAATTGACCTTGCAAGTGAGGCCTTATCAATGGATTAATCATATTAGTGCTGTGGGTGAACATAATTCACCAAATACATGGTCTATTTATATTTATAATATTGCTTTGGAAGTAGAAGAGTTAACTCTTTGGCAACTTTTCGGTCCATATGGTGCTATTGTTTCAGTTAAGATTATTAGGGATCATCAGACTAATAAAAGTAAAGGATATGGTTTTGTTACAATGAGAAATTACGACCAAGCTGCGATGGCAATACAAGCATTAAACGGATATCTATTGCACGGTCAACCTCTCTCTATTTTCGGTAAAGAGGCGCTGGTCGTGGCGGACTGCGAGAACTCTGCTGTAGCGGGGGGCGTCGGCCTCGCCGTGAGTAGCAAGGTATATCCAAGTCCGGGGGCGGCGCGCGGCGTGTGGGCGCTGCCACAGCCGCCCCCGTGCACGATGGCCGCAGAGGAATCTCTCCCACAGGGCTCACCCATGTCGCCGGATGCTCCAGTCGCACCACCCAGGACTATCACGAGTTTCAATCAATACTCCGATTTGCACCAACTAATATTTGAGGCGGTTCGATCAGGAGAAGTATCGGAAATCGAACGCCTGGTTGAAAAACTTGGAGTGGAAGTCTTGAATGCTCGGGACCAGCATGGCTATACTCCCGCACACTGGGCATCGCTTGATGGGAGCGTGGCGGTCATGCGATACCTCGTGGAAAGATCAGCTCCTGTCGATCTTTCCTGTCTTGGCACTCAGGGGCCGCGTCCGATACACTGGGCTTGCCGCAAAGGACATGCATCTATCGTTCAAGTTCTCCTTCAGGCCGGTGTTGCTGTCAATGCTGCAGATTTCAAAGGTTTGACACCTTTAATGACAGCTTGCATGTATGGTAAAACAGCCACAGCTGCTTATCTGTTAGGAATGGGTGCAGCTACAAGACTGTCTGATATAAACGGAGACACAGCCCTACATTGGGCGGCATATAAGGGACATGCAGATGTCGTTCGTCTTTTAATTTACTCTGGAGTTCCATTACACTGTACTGATAATTTTGGTTCGACACCCCTACATTTAGCATGTTTGTCGGGAAACTTAACTTGTGTTAGATTACTCTGTGAAAAGGTAAAGGCTGAGTTAGAACCGCGCGATAAAAATGGAAAAACACCGCTAATGCTAGCACAGAGCCACAGGCATGCAGAAGTTGTGAAATTACTGCAAAAGGAAATGAAACGTAAATCCCATTGGATACCCCCACTGTCAGAATTATGGGCGTTATTGTTCGGCGGCGCTGGTGATTCTAAAGGGCCACTGTTGTTCTTTTTAATCTCAGTTTTATTGTGGGGTTATCCTATACGTGATCCCGGATACGTGCCGCAGAATTCGGAAACATACTACAGAGCTATAAGACAAATCCCTTATTACGATAAATGGAAGAAGAGAAATATTATATTATCAAGACTGTGTCATACGTGTCGATGCTTAAGACCTCTGAGAGCAAAACATTGTCGCATCTGCAAACGTTGCGTAGCGTATTTTGACCATCACTGCCCGTTTATCTACAACTGTGTCGGAGTTCGCAATCGAATGTGGTTCTTCTTGTTCGTGATGAGCGTTGCGATCAACTGCACATTGTCGATCTACTTTGCCTGTTATTGTCTACTACTCGAGGGATTCGGTCTGCTGTATATGCTGGGGCTACTTGAAGCTATTACTTTTTGTGCCCTCGGTTGGATTTTGACTTGCACTTCGGTGCTGCACGCCTGTATGAACTTAACCACAAACGAAATGTTTAATTACAAACGATATCCATACTTGAGGGACAAACGAGGAAGATACCAAAATCCATTTTCACGTGGACCCATCATGAATCTGTTCGAGTTTTTCGTGTGCCTGCCGGATAAATGCGACGACCATGACATTTTTCACGAAGAAAGTATATAA

Protein

MSESCQDGNCQGNNEYGPEESPTKLIVNYIPEVMTQDMMFSLFSTMGKLESCKLIANRGYGFVEYTRPDDAVKARKAFNGLLMQNKTLKVSHALLNPELKPPTKPEADWNLYICNLPNELTLQVRPYQWINHISAVGEHNSPNTWSIYIYNIALEVEELTLWQLFGPYGAIVSVKIIRDHQTNKSKGYGFVTMRNYDQAAMAIQALNGYLLHGQPLSIFGKEALVVADCENSAVAGGVGLAVSSKVYPSPGAARGVWALPQPPPCTMAAEESLPQGSPMSPDAPVAPPRTITSFNQYSDLHQLIFEAVRSGEVSEIERLVEKLGVEVLNARDQHGYTPAHWASLDGSVAVMRYLVERSAPVDLSCLGTQGPRPIHWACRKGHASIVQVLLQAGVAVNAADFKGLTPLMTACMYGKTATAAYLLGMGAATRLSDINGDTALHWAAYKGHADVVRLLIYSGVPLHCTDNFGSTPLHLACLSGNLTCVRLLCEKVKAELEPRDKNGKTPLMLAQSHRHAEVVKLLQKEMKRKSHWIPPLSELWALLFGGAGDSKGPLLFFLISVLLWGYPIRDPGYVPQNSETYYRAIRQIPYYDKWKKRNIILSRLCHTCRCLRPLRAKHCRICKRCVAYFDHHCPFIYNCVGVRNRMWFFLFVMSVAINCTLSIYFACYCLLLEGFGLLYMLGLLEAITFCALGWILTCTSVLHACMNLTTNEMFNYKRYPYLRDKRGRYQNPFSRGPIMNLFEFFVCLPDKCDDHDIFHEESI

Catalytic Activity

hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein]

Similarity

Belongs to the DHHC palmitoyltransferase family.

Uniprot

A0A2H1V8T3   A0A212FG42   H9JM34   A0A2A4JFZ7   A0A2W1BZH8   A0A194R019   + More
A0A194PNW7   A0A0L7LB15   A0A084VL20   A0A182PDV8   A0A182XNS6   A0A182F647   A0A182JEN3   A0A182R155   Q7PWK8   Q17LW6   A0A182UUW1   A0A182LMR8   B0WB14   B4LSF8   B5DHZ9   B3MVH4   A0A1W4VBZ7   A0A0J9R186   B4P1Y8   B3N3X0   Q9VKB1   B4IE66   B4N775   A0A0M4E5I5   A0A0L0CMQ1   A0A1A9Z7X8   A0A195AYF8   A0A0L7RGX8   E9JD72   T1I5S7   A0A2A3EDW4   A0A0N0BF79   E2CAD7   A0A232F461   A0A336M051   A0A310SKS7   B4KI04   A0A087ZYY1  

EC Number

2.3.1.225

Pubmed

22118469    19121390    28756777    26354079    26227816    24438588    + More
12364791    17510324    20966253    17994087    15632085    22936249    17550304    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    26108605    21282665    20798317    28648823   

EMBL

ODYU01001259    SOQ37219.1    AGBW02008720    OWR52704.1    BABH01005825    BABH01005826    + More
NWSH01001519    PCG70997.1    KZ149911    PZC78116.1    KQ460883    KPJ11143.1    KQ459603    KPI92820.1    JTDY01001896    KOB72600.1    ATLV01014396    ATLV01014397    KE524970    KFB38664.1    AXCN02000795    AAAB01008984    EAA14821.2    CH477210    EAT47705.1    DS231876    EDS41972.1    CH940649    EDW64780.2    CH379060    EDY69936.2    CH902624    EDV33239.2    CM002910    KMY89878.1    CM000157    EDW88159.1    CH954177    EDV58822.1    AE014134    AY058389    AAF53165.1    AAL13618.1    CH480831    EDW45893.1    CH964182    EDW80216.2    CP012523    ALC39384.1    JRES01000186    KNC33492.1    KQ976701    KYM77231.1    KQ414596    KOC70089.1    GL771866    EFZ09193.1    ACPB03003574    KZ288269    PBC29973.1    KQ435809    KOX72968.1    GL453975    EFN75103.1    NNAY01001055    OXU25319.1    UFQS01000238    UFQT01000238    SSX01836.1    SSX22213.1    KQ760243    OAD61281.1    CH933807    EDW11286.2   

Proteomes

UP000007151    UP000005204    UP000218220    UP000053240    UP000053268    UP000037510    + More
UP000030765    UP000075885    UP000076407    UP000069272    UP000075880    UP000075886    UP000007062    UP000008820    UP000075903    UP000075882    UP000002320    UP000008792    UP000001819    UP000007801    UP000192221    UP000002282    UP000008711    UP000000803    UP000001292    UP000007798    UP000092553    UP000037069    UP000092445    UP000078540    UP000053825    UP000015103    UP000242457    UP000053105    UP000008237    UP000215335    UP000009192    UP000005203   

PRIDE

H9JM34    Q9VKB1   

Pfam

PF13606   Ank_3        + More
PF12796   Ank_2
PF01529   DHHC
PF00076   RRM_1
PF00023   Ank
PF15684   AROS

Interpro

IPR020683   Ankyrin_rpt-contain_dom        + More
IPR003954   RRM_dom_euk       
IPR002343   Hud_Sxl_RNA       
IPR002110   Ankyrin_rpt       
IPR000504   RRM_dom       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR001594   Palmitoyltrfase_DHHC       
IPR035979   RBD_domain_sf       
IPR036770   Ankyrin_rpt-contain_sf       
IPR023262   AROS       

SUPFAM

SSF48403   SSF48403        + More
SSF54928   SSF54928       

Gene 3D

1.25.40.20     3.30.70.330    

CDD

cd00204  ANK

ProteinModelPortal

A0A2H1V8T3   A0A212FG42   H9JM34   A0A2A4JFZ7   A0A2W1BZH8   A0A194R019   + More
A0A194PNW7   A0A0L7LB15   A0A084VL20   A0A182PDV8   A0A182XNS6   A0A182F647   A0A182JEN3   A0A182R155   Q7PWK8   Q17LW6   A0A182UUW1   A0A182LMR8   B0WB14   B4LSF8   B5DHZ9   B3MVH4   A0A1W4VBZ7   A0A0J9R186   B4P1Y8   B3N3X0   Q9VKB1   B4IE66   B4N775   A0A0M4E5I5   A0A0L0CMQ1   A0A1A9Z7X8   A0A195AYF8   A0A0L7RGX8   E9JD72   T1I5S7   A0A2A3EDW4   A0A0N0BF79   E2CAD7   A0A232F461   A0A336M051   A0A310SKS7   B4KI04   A0A087ZYY1  

PDB

6MOK     E-value=2.72527e-32,     Score=349

KEGG

101735339    K20032 palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225] | (RefSeq) probable protein S-acyltransferase

GO

GO:0016021   GO:0003723   GO:0019706   GO:0016746   GO:0005783   GO:0018230   GO:0006612   GO:0005794   GO:0018345   GO:0000166   GO:0005515   GO:0003676   GO:0008270   GO:0006520   GO:0006508   GO:0008237   GO:0043401   GO:0003707   GO:0051537  

Length:

763

Number of predicted TMHs:

2

Exp number of AAs in TMHs:

58.54982

Exp number, first 60 AAs:

0.00562

Total prob of N-in:

0.01781

outside

1  -  645

TMhelix

646  -  668

inside

669  -  674

TMhelix

675  -  697

outside

698  -  763

 

 

Pi

2.776778

Theta

3.357768

Tajima's D

-0.950028

CLR

4.704824

CSRT

0.146042697865107

Interpretation

Uncertain