Gene

KWMTBOMO07239

Pre Gene Modal

BGIBMGA010584

Annotation

chymotrypsinogen_precursor_[Bombyx_mori]

Location

Bomo_Chr12(+):8911210-8913617      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 4.648

CDS

ATGCGTTCGCTAGTGTTTTTCATTTTGTGCTTTGTGACCTACACAAGTAGTGAAAGTAGCGCCAACGAAGAATTTGTAGGATGGCTCGAAAAAGTTGGCATTAAAACGGCTGCAAAGATTAAGCAAGCGGAACAACACCAAATATTTATGCAGCGCATCGTTGGGGGAGCTATTGCGCCAATCAATTACCATCCATATTTGGCAGGTCTACTGATTGATATTAATGAATTGCAATCACCGGCCGCGTGCGGCGGATCGATCCTTACCCCTGCCAGCATCTTAACTGCAGCTCATTGCTGGTTCGATGGAAGAAATCGTGCAGTACGTTTCACTGTCGTACTGGGAACCCCATTCCTGTTCCATGGTGGCTTAAGGATTCAAGCGTCTTCCATTGCAGTTCATCATCAATACGACTTCAGAACGTTTGCAAATGACATTGCAATGCTGTACTTACCCCGTCGTATAATATTCAACCATGCGGTACAGCCAATTCCATTAGCCACTGATTCGCTTCTAAGCACTGACAAGGCAGGCATGTGGGCCGTTGCAGCTGGATATGGAAGATATTCTGATGTTATAAATCCTACGACAAACACGATGGCGAGAAATGTTTTTCTACAAACTATATCCTTAGAAACCTGCCGTGGCTATTACGGTAATGTAGTTTTGGATTCTAACATCTGCACTAGTGGAGTTGGCGGTGTTGGTATTTGCCGAGGAGATTCTGGAGGCCCATTAACTATTAACCACCAAGGAAAAGAATGGCTCATTGGTGTTAGCTCATTCGTGGCAAGGGACGGCTGCGAATTAGGTTTCCCGTCTGTTTTCGCCAGCGTACCTTCCTTCAGGGCCTGGATCCAACATCACATGATATTTTAA

Protein

MRSLVFFILCFVTYTSSESSANEEFVGWLEKVGIKTAAKIKQAEQHQIFMQRIVGGAIAPINYHPYLAGLLIDINELQSPAACGGSILTPASILTAAHCWFDGRNRAVRFTVVLGTPFLFHGGLRIQASSIAVHHQYDFRTFANDIAMLYLPRRIIFNHAVQPIPLATDSLLSTDKAGMWAVAAGYGRYSDVINPTTNTMARNVFLQTISLETCRGYYGNVVLDSNICTSGVGGVGICRGDSGGPLTINHQGKEWLIGVSSFVARDGCELGFPSVFASVPSFRAWIQHHMIF

Similarity

Belongs to the peptidase S1 family.

Uniprot

Q2F617   H9JM32   J7FDV8   A0A0M5KXW7   A0A2W1BWV2   A0A0L7L6E9   + More
C9W8F5   A0A1E1WJ19   A0A089QDB8   A0A194PHC5   A0A089RSY0   A0A194R1N4   A0A2H1VAW7   I6SJ48   A0A3S2LDG1   A0A2A4JTS9   Q1HPW8   A0A1B1LTR9   A0A3S2NMC5   I6TMX9   I6SJ44   A0A1E1WTE4   A0A1E1WDT0   A0A1E1WL73   A0A194PHE1   A0A2H1X112   A0A1E1WB13   A0A1E1W2N0   A0A2A4JJ19   A0A2A4JK09   A0A0N0PBU1   A0A2W1BAG4   A0A089QAL5   A0A2H1V6W6   A0A2H1VX12   E7D016   A0A0L7LI04   C9W8H9   J7FDV3   A0A2A4JSJ6   Q86M89   A0A2H1WCW9   A0A2A4JJV5   C9W8F9   A0A194Q0R8   A0PGD5   C9W8H8   A0A0N1PGY7   A0A0K8SR13   C9W8G0   E7D005   A0A2A4K0B4   A0A089QFN1   A0PGE0   A0A0K8SS51   D7RZZ7   D7RZZ6   B6CMF0   D2Y4U4   D7RZZ8   A0A2A4JJQ3   A0A2A4K202   A0A2A4JJ77   A0A2H1VW13   C7FF06   E0W9N7   D7RZZ9   A0A0M4MQT7   A0A2H1X2D3   A0A3S2NRK5   E0W9N4   A0A089Q9N5   H9JCY0   C9W8J3   E7D003   A0A2A4JKX6   B4X991   E7D015   A0A0N0PCX7   H9JG67   E7D017   A0A2A4JIX9   A0A2A4JFM8   A0A089QAK4   A0A2H1V6P6   A0A0L7LB31   C9W8G7   O18438   A0A3S2L6H3   A0A2A4J8W1  

Pubmed

19121390    22228503    28756777    26227816    20824821    26354079    + More
19194984    20696895    18760362    20149796    21322004    9404008   

EMBL

DQ311255    ABD36200.1    BABH01005812    JN252045    AFM28258.1    KR024677    + More
ALE15219.1    KZ149911    PZC78104.1    JTDY01002618    KOB71083.1    FJ205399    ACR15968.2    GDQN01004055    JAT86999.1    KM083792    AIR09773.1    KQ459603    KPI92811.1    KM083781    AIR09762.1    KQ460883    KPJ11150.1    ODYU01001570    SOQ37967.1    JQ904142    AFM77772.1    RSAL01000035    RVE51334.1    NWSH01000639    PCG75098.1    DQ443284    ABF51373.1    KX380993    ANS56509.1    RVE51335.1    JQ904138    AFM77768.1    JQ904137    AFM77767.1    GDQN01000810    JAT90244.1    GDQN01005957    JAT85097.1    GDQN01003329    JAT87725.1    KQ459604    KPI92468.1    ODYU01012588    SOQ59001.1    GDQN01006881    JAT84173.1    GDQN01009850    JAT81204.1    NWSH01001222    PCG72057.1    PCG72058.1    KQ460813    KPJ12139.1    KZ150191    PZC72392.1    KM083794    AIR09775.1    ODYU01000971    SOQ36526.1    ODYU01004792    SOQ45042.1    HM990186    ADT80834.1    JTDY01001059    KOB74999.1    FJ205425    ACR15992.2    JN252035    AFM28248.1    NWSH01000651    PCG75015.1    AY251276    AAO75039.1    ODYU01007826    SOQ50918.1    PCG72056.1    FJ205404    ACR15972.2    KQ459581    KPI99177.1    AY618890    AAV33653.1    FJ205424    ACR15991.1    KQ461033    KPJ09997.1    GBRD01010002    JAG55822.1    FJ205405    ACR15973.2    HM990175    ADT80823.1    NWSH01000291    PCG77701.1    KM083780    AIR09761.1    AY618895    AAV33658.1    GBRD01009676    JAG56148.1    HM209420    ADI32881.1    HM209419    ADI32880.1    EU325550    ACB54940.1    GU323796    ADA83701.1    HM209421    ADI32882.1    PCG72059.1    PCG77700.1    NWSH01001385    PCG71452.1    SOQ45041.1    GQ354838    ACU00133.1    FJ205439    ADM35108.1    HM209422    ADI32883.1    KR024678    ALE15220.1    ODYU01012894    SOQ59427.1    RSAL01000119    RVE46738.1    FJ205401    ADM35105.1    KM083788    AIR09769.1    BABH01027594    FJ205442    ACR16006.2    HM990173    ADT80821.1    PCG72060.1    EF531627    ABR88238.1    HM990185    ADT80833.1    KQ460401    KPJ14971.1    BABH01002097    HM990187    ADT80835.1    PCG72055.1    NWSH01001552    PCG70877.1    KM083784    AIR09765.1    SOQ36525.1    JTDY01001894    KOB72615.1    FJ205412    ACR15980.1    Y12273    CAA72952.1    RVE46739.1    NWSH01002619    PCG67833.1   

Proteomes

UP000005204    UP000037510    UP000053268    UP000053240    UP000283053    UP000218220    + More

PRIDE

Q2F617    H9JM32    Q1HPW8    H9JCY0    H9JG67   

Pfam

PF00089   Trypsin

Interpro

IPR001254   Trypsin_dom        + More
IPR018114   TRYPSIN_HIS       
IPR009003   Peptidase_S1_PA       
IPR001314   Peptidase_S1A       
IPR033116   TRYPSIN_SER       
IPR036179   Ig-like_dom_sf       

SUPFAM

SSF50494   SSF50494        + More
SSF48726   SSF48726       

CDD

cd00190  Tryp_SPc

ProteinModelPortal

Q2F617   H9JM32   J7FDV8   A0A0M5KXW7   A0A2W1BWV2   A0A0L7L6E9   + More
C9W8F5   A0A1E1WJ19   A0A089QDB8   A0A194PHC5   A0A089RSY0   A0A194R1N4   A0A2H1VAW7   I6SJ48   A0A3S2LDG1   A0A2A4JTS9   Q1HPW8   A0A1B1LTR9   A0A3S2NMC5   I6TMX9   I6SJ44   A0A1E1WTE4   A0A1E1WDT0   A0A1E1WL73   A0A194PHE1   A0A2H1X112   A0A1E1WB13   A0A1E1W2N0   A0A2A4JJ19   A0A2A4JK09   A0A0N0PBU1   A0A2W1BAG4   A0A089QAL5   A0A2H1V6W6   A0A2H1VX12   E7D016   A0A0L7LI04   C9W8H9   J7FDV3   A0A2A4JSJ6   Q86M89   A0A2H1WCW9   A0A2A4JJV5   C9W8F9   A0A194Q0R8   A0PGD5   C9W8H8   A0A0N1PGY7   A0A0K8SR13   C9W8G0   E7D005   A0A2A4K0B4   A0A089QFN1   A0PGE0   A0A0K8SS51   D7RZZ7   D7RZZ6   B6CMF0   D2Y4U4   D7RZZ8   A0A2A4JJQ3   A0A2A4K202   A0A2A4JJ77   A0A2H1VW13   C7FF06   E0W9N7   D7RZZ9   A0A0M4MQT7   A0A2H1X2D3   A0A3S2NRK5   E0W9N4   A0A089Q9N5   H9JCY0   C9W8J3   E7D003   A0A2A4JKX6   B4X991   E7D015   A0A0N0PCX7   H9JG67   E7D017   A0A2A4JIX9   A0A2A4JFM8   A0A089QAK4   A0A2H1V6P6   A0A0L7LB31   C9W8G7   O18438   A0A3S2L6H3   A0A2A4J8W1  

PDB

2HLC     E-value=2.72256e-26,     Score=293

KEGG

692868    no KO assigned | (RefSeq) chymotrypsinogen

GO

GO:0004252   GO:0008236   GO:0006508   GO:0020037   GO:0005737   GO:0006520   GO:0008237   GO:0043401   GO:0003707   GO:0051537  

SignalP

Position:   1 - 17,         Likelihood:  0.994083

 

 

Length:

292

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.49772

Exp number, first 60 AAs:

0.09889

Total prob of N-in:

0.01767

outside

1  -  292

 

 

Pi

2.6659

Theta

5.798099

Tajima's D

-1.411134

CLR

1.353793

CSRT

0.0670966451677416

Interpretation

Uncertain