Gene

KWMTBOMO07237

Annotation

cytochrome_P450_CYP6AE9_[Bombyx_mori]

Location

Bomo_Chr12(-):8846491-8853829      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.357 PlasmaMembrane   Reliability : 1.371

CDS

ATGTTCTTACTGATTAATATTTGTGTTATTTTATTTGTGATATACTATTTAGTGACCAAAAAGTATAGTTATTGGAGAAACAGAAATGTTTCTCACGAAAAACCAGTGCTTCTTTTGGGAAATTACGGTGACTTAATCCTGCAAAAAAAGAATTTTGGTGAGATGGCCCAAGCGATTTGTCAGAAGTTCCCTGGGGAGCCTGTTGTTGGAGCTTTTTTTGGAACAGAACCGGTTCTTATACCTCAGGACCCTGAAGTCATCAAAACCATATTAACCAAAGATTTCTACTATTTTAATGGAAGAGAAATATCAGAGCATGTTCACAAGGAACTCTTGTCGTACAACTTATTTGCCACGTATGGAGACGAATGGAAAATATTGAGACAAAACCTAACTCCAATTTTTTCTACTGCAAAACTGAAAAGTATGTTTACTCTAATTGAGAAATGTTCAAAATCTTTTCAAAATCTACTGGAAGATGAAACGAAAATATCGAAAGAGCTAGAAGTGAGAACTTTGATGCAGAGGTTTACAATAGAATGTATCGGATCGTGTATTTTTGGAGTAGATACTGACACATTGGGAAATGATAAAATGAATCCATTTAAAGCAGCAGGCAGCCAATTGTCAGACTTTTCGAGGCTTGTTTTTGTTAAAGGGATAGTAAGAGCAATTTGGCCCACTTTATTTTACGCCCTTGGATTTAAAACGTTTACTACTGAATTAGATATTTTCAAAAAACTGGTGAATGCTGTTTTTGCTCAAAGAAAACACAAGCCAACAACAAGGAATGATTTTGTTGACTTAATTTTGACATGGAAGAATAACAATACCATTACCGGAGACAGCATAGGAAGTTTTAAAAATAGCGATAAAACAAAATTTTCAATTGATGTTAATGACGATTTACTTTTAGCTCAGTGCTTAGTATTTTTTGCTGCGGGCTTTGAAACTTCTGCAATGACGTCGAGTTACACTTTACACGAGCTAGCGAAAAATCAAAGAGCTTTAAAGAAAGCCTGCGATGAGGTCGACGCTTATTTATTGCGTCACGGTAACAAGGTCAACTACGATTGTGTCACGGAATTGCCTTATCTCGAGGCATGCATTGAAGAGACTCTTCGTCTATATCCAGTTCTTGGTATAATAACTAGAGAAGTGATGGAAGACTACGTTTTGCTTGATAAAATACATTTAAAGAAAGGAGATCGTATACATGTACCGGTATTTCATCTGCATCATAATCCTGAACATTTTCCGAACCCGGAAGAGTATCGACCGGAGCGATTTTATGGTGAAGAAAAACGTAAGGTGAAGCCGTATACCTATTTACCATTTGGTGAAGGCCCACGAATTTGCATTGGGATGAGATTTGCAAAAATGCAGTCTATAGCAGGCTTGATAACGATTTTGAAGAAATTCAGGCTGGAACTACCCGAAGGTGCACCTACTAAGATTGAGTTCAAGCCTGAAGCCTTTGTGACTACACCTAAAGATCTAATCAAAATCAAATTTTTGGAACGTGAAGGATGGCAGCAAAGAGTTTTTGTTTAA

Protein

MFLLINICVILFVIYYLVTKKYSYWRNRNVSHEKPVLLLGNYGDLILQKKNFGEMAQAICQKFPGEPVVGAFFGTEPVLIPQDPEVIKTILTKDFYYFNGREISEHVHKELLSYNLFATYGDEWKILRQNLTPIFSTAKLKSMFTLIEKCSKSFQNLLEDETKISKELEVRTLMQRFTIECIGSCIFGVDTDTLGNDKMNPFKAAGSQLSDFSRLVFVKGIVRAIWPTLFYALGFKTFTTELDIFKKLVNAVFAQRKHKPTTRNDFVDLILTWKNNNTITGDSIGSFKNSDKTKFSIDVNDDLLLAQCLVFFAAGFETSAMTSSYTLHELAKNQRALKKACDEVDAYLLRHGNKVNYDCVTELPYLEACIEETLRLYPVLGIITREVMEDYVLLDKIHLKKGDRIHVPVFHLHHNPEHFPNPEEYRPERFYGEEKRKVKPYTYLPFGEGPRICIGMRFAKMQSIAGLITILKKFRLELPEGAPTKIEFKPEAFVTTPKDLIKIKFLEREGWQQRVFV

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Uniprot

A5HKM1   A9QW15   L0N6M3   A0A286QUG7   J7FKN1   A0A2A4JWC6   + More
A0A2W1BGY9   A0A068F0X7   D5L0M5   A0A248QG18   Q2XSW1   A0A2H1V0E7   A0A068ETU4   D5L0M6   H2CZE9   H2CZF1   A0A068F1Z7   A0A248QEF8   J7FJF3   A0A068EVK6   Q7YZS2   Q069I9   F4YCW0   A0A248QHF4   A0A0K0YD30   A0A068EU65   A0A2H1WID4   A0A068F0X2   A0A2A4J2E3   A0A2H1VU17   J7FJF2   A0A2A4JAM9   A0A068ETU8   A0A2A4J918   A0A2A4JAK3   C1LZ54   A0A2A4J7V4   A0A0C5C1I6   A0A248QEH8   A0A068EWQ0   A0A248QEX7   B3VT94   A0A172MF86   A0A2A4J698   A0A2H1VSH4   A0A068EWQ5   A0A068EU72   A0A0A7DH57   A0A068EVL0   A0A068EVD2   C7U1L4   A0A0K8TV92   D2JLK6   A0A0L7LJH7   A0A2H1VSG7   H9JUM8   D6MLU9   L0N766   L0N7C5   A0A0A7DGX3   A0A0K8TUL3   A0A0C5CGV6   A4GUB8   B6VFR9   A0A3S2P9Y7   A0A2H1W4N2   A9YXV8   A0A0K8TUI1   A0A3S2LFF7   A5JM34   A4GUB9   A9QW13   J7FKN2   A0A1V0D9D6   A5HG34   L0N6H5   A3RIC0   A0A0L7LRY0   W5VY13   H9JUM4   A0A0N1IP03   A0A0L7KJY7   A0A222NX20   A0A0A7DH65   A0A0A7DH10   A0A0N1ID06   A0A0L7KVL1   A0A1V0D9D9   A0A1V0D9E0   H9JUM5   X5D9B5   A0A2H1V048   A5HG33   H9JUM6   A0A0A7DG86   A0A3S2LW02   A0A0A7DH14   Q4JHE4   I7GGY7   Q52S21  

Pubmed

28881445    22984814    28756777    19909380    25315858    15606809    + More
17982444    26017144    19954531    26227816    19121390    26354079    24361403    17119627   

EMBL

EF535809    ABQ08711.1    EU273877    ABX64440.1    AK343206    BAM73892.1    + More
KX443431    ASO98006.1    JX310077    AFP20588.1    NWSH01000502    PCG75998.1    KZ150141    PZC72944.1    KM016743    AID54895.1    GU731530    ADE05580.1    KX443433    ASO98008.1    DQ256407    ABB69054.1    ODYU01000082    SOQ34236.1    KM016735    AID54887.1    GU731531    ADE05581.1    JN375489    AEY75583.1    JN375491    AEY75585.1    KJ671576    AID55428.1    KX443430    ASO98005.1    JX310083    AFP20594.1    KM016736    AID54888.1    AY295774    AAP83689.1    DQ986461    JN176574    ABI84381.1    AET11931.1    GU937509    ADW23116.1    KX443432    ASO98007.1    KR095600    AKS48888.1    KM016737    AID54889.1    ODYU01008863    SOQ52829.1    KM016738    AID54890.1    NWSH01003425    PCG66327.1    ODYU01004424    SOQ44278.1    JX310078    AFP20589.1    NWSH01002369    PCG68453.1    KM016740    AID54892.1    PCG68451.1    PCG68452.1    FN356971    CAX94849.1    NWSH01002736    PCG67604.1    KP001126    AJN91171.1    KX443434    ASO98009.1    KM016739    AID54891.1    KX443435    ASO98010.1    EU807990    ACF17813.2    KU145393    ANC96676.1    PCG67605.1    ODYU01004193    SOQ43795.1    KM016744    AID54896.1    KM016742    AID54894.1    KJ645906    AIJ00763.1    KM016741    AID54893.1    KJ671575    AID55427.1    FN544262    CBB07053.1    GCVX01000049    JAI18181.1    GQ915322    ACZ97416.2    JTDY01000942    KOB75351.1    ODYU01004192    SOQ43793.1    BABH01022705    GQ241737    ADD70250.1    AK343205    BAM73891.1    AK289291    AK343204    BAM73818.1    BAM73890.1    KJ645907    AIJ00764.1    GCVX01000058    JAI18172.1    KP001127    AJN91172.1    EF432656    ABO21682.1    FJ387169    ACJ10074.1    RSAL01000158    RVE45548.1    ODYU01006311    SOQ48049.1    EU309477    ABY40426.1    GCVX01000081    JAI18149.1    RVE45547.1    EF547545    ABQ42339.1    EF432657    ABO21683.1    EU273875    ABX64438.1    JX310082    AFP20593.1    KY212045    ARA91609.1    EF528486    ABP99020.1    AK289290    BAM73817.1    EF415296    ABN71367.1    JTDY01000272    KOB77971.1    KF853191    AHH92929.1    BABH01022694    KQ460655    KPJ12961.1    JTDY01009617    KOB63214.1    KX844829    ASQ44127.1    KJ645905    AIJ00762.1    KJ645904    AIJ00761.1    KQ459388    KPJ01135.1    JTDY01005369    KOB67074.1    KY212043    ARA91607.1    KY212044    ARA91608.1    KF701137    AHW57307.1    ODYU01000083    SOQ34238.1    EF528485    ABP99019.1    BABH01022698    KJ645908    AIJ00765.1    RVE45546.1    KJ645909    AIJ00766.1    DQ088989    AAY89329.1    AB236319    BAE45261.2    AY971374    AAX84943.1   

Proteomes

UP000218220    UP000037510    UP000005204    UP000283053    UP000053240    UP000053268    + More

PRIDE

A5HKM1    L0N6M3    H9JUM8    D6MLU9    L0N766    L0N7C5    + More
A4GUB8    B6VFR9    A5JM34    A4GUB9    A5HG34    L0N6H5    A3RIC0    H9JUM4    H9JUM5    A5HG33    H9JUM6   

Pfam

PF00067   p450        + More
PF09453   HIRA_B

Interpro

IPR036396   Cyt_P450_sf        + More
IPR002401   Cyt_P450_E_grp-I       
IPR017972   Cyt_P450_CS       
IPR001128   Cyt_P450       
IPR002403   Cyt_P450_E_grp-IV       
IPR019015   HIRA_B_motif       
IPR002402   Cyt_P450_E_grp-II       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

A5HKM1   A9QW15   L0N6M3   A0A286QUG7   J7FKN1   A0A2A4JWC6   + More
A0A2W1BGY9   A0A068F0X7   D5L0M5   A0A248QG18   Q2XSW1   A0A2H1V0E7   A0A068ETU4   D5L0M6   H2CZE9   H2CZF1   A0A068F1Z7   A0A248QEF8   J7FJF3   A0A068EVK6   Q7YZS2   Q069I9   F4YCW0   A0A248QHF4   A0A0K0YD30   A0A068EU65   A0A2H1WID4   A0A068F0X2   A0A2A4J2E3   A0A2H1VU17   J7FJF2   A0A2A4JAM9   A0A068ETU8   A0A2A4J918   A0A2A4JAK3   C1LZ54   A0A2A4J7V4   A0A0C5C1I6   A0A248QEH8   A0A068EWQ0   A0A248QEX7   B3VT94   A0A172MF86   A0A2A4J698   A0A2H1VSH4   A0A068EWQ5   A0A068EU72   A0A0A7DH57   A0A068EVL0   A0A068EVD2   C7U1L4   A0A0K8TV92   D2JLK6   A0A0L7LJH7   A0A2H1VSG7   H9JUM8   D6MLU9   L0N766   L0N7C5   A0A0A7DGX3   A0A0K8TUL3   A0A0C5CGV6   A4GUB8   B6VFR9   A0A3S2P9Y7   A0A2H1W4N2   A9YXV8   A0A0K8TUI1   A0A3S2LFF7   A5JM34   A4GUB9   A9QW13   J7FKN2   A0A1V0D9D6   A5HG34   L0N6H5   A3RIC0   A0A0L7LRY0   W5VY13   H9JUM4   A0A0N1IP03   A0A0L7KJY7   A0A222NX20   A0A0A7DH65   A0A0A7DH10   A0A0N1ID06   A0A0L7KVL1   A0A1V0D9D9   A0A1V0D9E0   H9JUM5   X5D9B5   A0A2H1V048   A5HG33   H9JUM6   A0A0A7DG86   A0A3S2LW02   A0A0A7DH14   Q4JHE4   I7GGY7   Q52S21  

PDB

6MJM     E-value=8.8031e-51,     Score=507

KEGG

100126548    K14999 cytochrome P450 family 6 [EC:1.14.-.-] | (RefSeq) Cyp6ae9, CYP6AE8; cytochrome P450 CYP6AE9

GO

GO:0020037   GO:0005506   GO:0016705   GO:0004497   GO:0016021   GO:0046872   GO:0005737   GO:0006520   GO:0006508   GO:0008237   GO:0043401   GO:0003707   GO:0051537   GO:0055114  

Length:

517

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

17.86235

Exp number, first 60 AAs:

17.59359

Total prob of N-in:

0.97121

POSSIBLE N-term signal

sequence

inside

1  -  1

TMhelix

2  -  19

outside

20  -  517

 

 

Pi

0.080188

Theta

0.769324

Tajima's D

-2.430139

CLR

576.685565

CSRT

0

Interpretation

Possibly Positive selection