The Silkworm Genome Information Database

Gene

KWMTBOMO07202

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_disks_large_1_tumor_suppressor_protein_[Bombyx_mori]

Location

Bomo_Chr12(-):7819454-7838956 View in EpiBrowser

Location in the cell

Nuclear Reliability : 3.426

CDS

ATGCCAGTTCGTAAGCAAGAGGCGCATCGAGCTCTAGAATTACTTGAAGATTATCATAGCAAGCTAATAAAGCCACAAGACCGGCAGTTGAGGCTTGCTATCGAAAGAGTCATCAGAATTTTTAAATCAAGATTATTTCAAGCATTACTCGATATCCAAGAGTTCTATGAGCTCACTCTCCTCGATGATACGAAGTCAGTACAACAGAAAACTGCAGAAACAATCCGTATCGCTAACAAGTGGGAATTGGACAGCAACAGACGAGAGATATCAACGGATGAAATTGAATATAGATCGGTATCAAATGCATTTCTACACGACAACAATAAGAAGTCTGAATCACGTAATGAGACACCAGACTCGGGTAAGGTGCGTTCTGTCGTATCACCAAGTGATGAAGTTGAAGAAAAGAAAGTGAGTTTATTAATGAGTTCTGTTTGTTTTTCTAAAATTTTGTTATGA

Protein

MPVRKQEAHRALELLEDYHSKLIKPQDRQLRLAIERVIRIFKSRLFQALLDIQEFYELTLLDDTKSVQQKTAETIRIANKWELDSNRREISTDEIEYRSVSNAFLHDNNKKSESRNETPDSGKVRSVVSPSDEVEEKKVSLLMSSVCFSKILL

Similarity

Belongs to the MAGUK family.

Uniprot

A0A3S2NMH9 A0A194R0Z5 A0A0U2HMF0 A0A194PH93 A0A212FL53 A0A0L7LG44 + More
T1PNU5 T1PLH7

Pubmed

26354079 22118469 26227816

EMBL

RSAL01000003 RVE54756.1 KQ460883 KPJ11184.1 KP308212 ALH43430.1 + More
KQ459603 KPI92776.1 AGBW02007871 OWR54462.1 JTDY01001258 KOB74375.1 KA649633 AFP64262.1 KA649632 AFP64261.1

Proteomes

UP000283053 UP000053240 UP000053268 UP000007151 UP000037510

Pfam

PF09058   L27_1        + More
PF00018   SH3_1
PF00595   PDZ
PF00625   Guanylate_kin

Interpro

IPR015143   L27_1        + More
IPR004172   L27_dom
IPR036892   L27_dom_sf
IPR036028   SH3-like_dom_sf
IPR027417   P-loop_NTPase
IPR001478   PDZ
IPR020590   Guanylate_kinase_CS
IPR036034   PDZ_sf
IPR016313   DLG1-like
IPR008145   GK/Ca_channel_bsu
IPR008144   Guanylate_kin-like_dom
IPR001452   SH3_domain

SUPFAM

SSF101288   SSF101288        + More
SSF50044   SSF50044
SSF50156   SSF50156
SSF52540   SSF52540

ProteinModelPortal

A0A3S2NMH9 A0A194R0Z5 A0A0U2HMF0 A0A194PH93 A0A212FL53 A0A0L7LG44 + More
T1PNU5 T1PLH7

PDB

4RP5 E-value=7.58204e-30, Score=319

KEGG

101744274 K12076 disks large protein 1 | (RefSeq) disks large 1 tumor suppressor protein

PATHWAY

04391 Hippo signaling pathway - fly - Bombyx mori (domestic silkworm)

GO

GO:0005515 GO:0005840 GO:0006412 GO:0019843 GO:0005622 GO:0004656 GO:0005783 GO:0016702 GO:0016295 GO:0016296

Length:

153

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.00031

Exp number, first 60 AAs:

0.00031

Total prob of N-in:

0.39305

outside

1 - 153

Pi

161.683687

Theta

161.625277

Tajima's D

-1.238363

CLR

11.465999

CSRT

0.0990450477476126

Interpretation

Uncertain

Sequence

Summary

Ontologies

Topology

Population Genetic Test Statistics