Gene

KWMTBOMO07201  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010382

Annotation

PREDICTED:_LOW_QUALITY_PROTEIN:_disks_large_1_tumor_suppressor_protein_[Bombyx_mori]

Location

Bomo_Chr12(-):7802128-7818116      View in EpiBrowser

Location in the cell

Nuclear   Reliability : 1.974

CDS

ATGACAGAGAGAAGGAAGAAAAAGTCTCATAATGGATTTCTTCGGAAAGTCTCTTCACTATTTAATCTTGATACGGCTCACGTCGCATCATCTGAAATGAAGCAGTTACAGGTTAATGGCATAGAAGGTGGAGCAAATGAAAGAACACAGGGTGAGGATGGCTACATTTACCTCTCGGTGGCACTGTCTCGAGCTGGTGGTGCTGGCTTGGGCTTCAGCATTGCAGGAGGGTCTGACAATCCCCATGTGGCAGATGACCCTCATATCTATGTCACAAAGCTCATACCTGGTGGTGCTGCTGCAGCCAGTCAGTTACTGATTAATGATGCTATTTTACAGGTGAATGATGTGAATGTAGAAAATGTGACACATGCTGAAGCGGTTGATGCACTGAAAAAGGCTGGTAGTACTGTGAGATTGAAAGTGCGACGTCGAGCTATAGAAGATACCCTAAACGTGTCACAAGTGTCAAACAAAGAGGAATCTGTGGAAATAGAACTTATAAAAGGTGGCTCTGGCTTGGGCTTCAGTATAGCAGGCGGACTCGGTAACCAACACATACCCGGTGACAACGGCATTTACGTTACCAAAATCATGGCCGGCGGCGCTGCGCATCAAGATGGACGTTTAAGAGTTGGTGATAAATTGCTTATGGTCAAAAACACTTCTAACGGAGATGTCAATTTGGATAACGTGACACACGAGGATGCCGTGGCCGCTCTAAAGGCAACAGGAGAACGCGTGTTGCTAGTTTTGGTACCAGGGCCGAGACACGGACAACCCTCGCCGCGCACTTCTCGAGCTAACACACCGTCGAGCGCAGCAAATTCTCTCCGACGCGAAGACGCAACGGACGGCGGCGAGGAGGTACGCGTGGTGGAGCTGGAGAAAGGTCCCTCGGGCCTGGGGTTCAACATCGTCGGTGGCGAAGACGGGCACGGCATCTACGTTTCTTTCCTGTTGGCCGGCGGACCTGCGGAGAGGTCCGGCGCTCTACGGAGAGGAGACCGTCTGCTCGCAGTCAACGATCTTGACATATCGCACGCCACACACGAACAGGCCGCCAAAGCCCTGAAGAGCACGGGTCAAATTGTTAAATTGACTGTTGTGTATCGTCCACAAGAATACAATAAGTTTGAAGCACGAATCAATGAATTGAAACAACATCATACGCTATTACGGACATCTCAAAAACGATCCTTGTATGTAAGAGCATTATTTGACTACGACCCCATTCGAGACGATGGTCTACCTTCGAGAGGATTGCCGTTTCGATATGGCGATATATTGCATGTTACAAATGCGTCCGATGACGAATGGTGGCAAGCCAGAAGGCTGGGTCAGGATAAAGTGGACACCGATGCTATCGGTATAATTCCTTCGAAACGTCGATGGGAAAGAAAACAGCGGGCACGCGATCGACAAGTTAAATTCCAGGGACAGGGTACACCGGTCAGTACGAGCCAATCCACTCTGGAAAGGAAAAAGAAAACTTTATCTTTCAGTAGAAAATTCCCATTCATGAAGAGTCGAGAAGACGGCAAATCTGAAGATGGTTCCGATCAAGAACCTTTCATGCTTTGTTACACGCAGGAGGACGCTAACGCTGACGGTCAAGACGAGACGGTGTTGTCTTACGAAACAGTTCAGCAATTGACGATCGCGTACACTCGGCCCGTGATAATATTGGGCCCATTGAAAGATAGAATAAACGACGACCTCATTTCCGAGTTCCCTGACAAGTTTGGAAGCTGCGTGCCTCATACGACACGGCCAAGACGCGACTACGAGGTGGACGGGCGGGACTACCACTTCGTGGCCAGCCGCGAGCAGATGGAGCGCGACATACAGAATCACCTGTTCATCGAGGCCGGCCAGTACAACGACAATCTGTACGGAACGTCCGTGGCATCCGTGCGAGAAGTCGCCGAGAAGGGCAAGCATTGCATTTTGGACGTCAGCGGTAACGCAATCAAGAGATTGCAAGTAGCACAACTATTCCCTATTGCCATATTTATCAAACCAAAGAGTGTAGAGTCTATAATGGAAATGAACAAGAGAATGACAGAAGAACAAGCGAAGAAAACTTATGAACGTGCCCTTAAAATGGAGCAAGAATTCGCTGAATATTTTACTGGTTAG

Protein

MTERRKKKSHNGFLRKVSSLFNLDTAHVASSEMKQLQVNGIEGGANERTQGEDGYIYLSVALSRAGGAGLGFSIAGGSDNPHVADDPHIYVTKLIPGGAAAASQLLINDAILQVNDVNVENVTHAEAVDALKKAGSTVRLKVRRRAIEDTLNVSQVSNKEESVEIELIKGGSGLGFSIAGGLGNQHIPGDNGIYVTKIMAGGAAHQDGRLRVGDKLLMVKNTSNGDVNLDNVTHEDAVAALKATGERVLLVLVPGPRHGQPSPRTSRANTPSSAANSLRREDATDGGEEVRVVELEKGPSGLGFNIVGGEDGHGIYVSFLLAGGPAERSGALRRGDRLLAVNDLDISHATHEQAAKALKSTGQIVKLTVVYRPQEYNKFEARINELKQHHTLLRTSQKRSLYVRALFDYDPIRDDGLPSRGLPFRYGDILHVTNASDDEWWQARRLGQDKVDTDAIGIIPSKRRWERKQRARDRQVKFQGQGTPVSTSQSTLERKKKTLSFSRKFPFMKSREDGKSEDGSDQEPFMLCYTQEDANADGQDETVLSYETVQQLTIAYTRPVIILGPLKDRINDDLISEFPDKFGSCVPHTTRPRRDYEVDGRDYHFVASREQMERDIQNHLFIEAGQYNDNLYGTSVASVREVAEKGKHCILDVSGNAIKRLQVAQLFPIAIFIKPKSVESIMEMNKRMTEEQAKKTYERALKMEQEFAEYFTG

Similarity

Belongs to the MAGUK family.

Uniprot

A0A2A4JR09   A0A2A4JRK4   A0A2H1W7K0   A0A2A4JRB3   A0A0U2HMF0   A0A2A4JR48   + More
A0A2A4JRZ5   A0A194PH93   A0A212FL53   A0A194R1R0   A0A2A4JQD3   A0A2A4JQA2   A0A3S2PLC9   A0A1Y1MJX2   A0A2A4JQH7   A0A1Y1MJV2   V5GV54   F5HSC5   A0A0C9RXG9   V5GR91   V5G281   A0A1Y1MJW0   A0A154P021   A0A0P4VLH1   A0A0V0G9P6   A0A224X883   A0A069DWP4   V5I8P0   A0A1Y1MJV4   A0A3L8DUI6   A0A146LP79   A0A026W6I5   A0A1I8PWD6   A0A1B6K8F3   A0A1B6L875   A0A1B6LX85   T1J4T3   A0A1E1X2C6   A0A224YX20   A0A131YU35   A0A293LYS5   A0A131Y0Z9   A0A2H5BFB1   A0A2C9KA59   A0A2C9KA53   A0A2C9KA56   K9IN98   K9INA8   A0A2C9KA55   A0A3B1JY72   A0A3B1JEF9   L5MHD9   A0A2Y9KH23   A0A2C9KAB4   A0A384DIE7   A0A384DHW2   M1EN05   M3XXD9   A0A3Q7UTC4   A0A384DIF1   F1PCU2   A0A3Q2KRT3   A0A2I2UWT1   A0A2Y9KAM3   A0A3Q7RJX8   A0A3Q7VS47   A0A3Q2I4R1   A0A3Q2IA28   A0A2Y9H9G0   A0A2I2TZZ7   A0A3Q7RLN9   A0A2Y9HF24   A0A3Q2HDR8   A0A3Q2LA49   A0A3Q7PPZ2   A0A3Q7PPV9   A0A2I2V3W9   A0A3Q7SUT2   S7N7F4   A0A337SSR6   A0A3Q7SUT6   A0A3Q7PEQ3   A0A3Q7RKD5   A0A3Q7RVM8   A0A3Q7RLP4   A0A3Q7RJX4   B0LUR1   H3BAN3   L5L2E5   A0A3Q7PPW5   W5QGN5   A0A2U3ZBD9   A0A3Q7WBI5   A0A384DHP6   L8IHB4   A0A3Q2I1P2   A0A3Q7RLN3   A0A3Q7VS56   A0A2Y9HFZ3   A0A2Y9H969  

Pubmed

26354079    22118469    28004739    27129103    26334808    30249741    + More
26823975    24508170    28503490    28797301    26830274    29228898    15562597    25329095    24813606    23236062    16341006    19892987    17975172    18182049    9215903    23258410    20809919    22751099   

EMBL

NWSH01000781    PCG74249.1    PCG74244.1    ODYU01006772    SOQ48926.1    PCG74248.1    + More
KP308212    ALH43430.1    PCG74246.1    PCG74243.1    KQ459603    KPI92776.1    AGBW02007871    OWR54462.1    KQ460883    KPJ11185.1    PCG74247.1    PCG74245.1    RSAL01000003    RVE54755.1    GEZM01029646    JAV86014.1    PCG74251.1    GEZM01029648    JAV86012.1    GALX01004353    JAB64113.1    AB630176    BAK23256.1    GBYB01013825    JAG83592.1    GALX01004354    JAB64112.1    GALX01004351    JAB64115.1    GEZM01029649    JAV86011.1    KQ434787    KZC05269.1    GDKW01003320    JAI53275.1    GECL01002151    JAP03973.1    GFTR01007839    JAW08587.1    GBGD01000633    JAC88256.1    GALX01004350    JAB64116.1    GEZM01029647    JAV86013.1    QOIP01000004    RLU23408.1    GDHC01010047    JAQ08582.1    KK107373    EZA51665.1    GEBQ01032251    JAT07726.1    GEBQ01020121    JAT19856.1    GEBQ01011690    JAT28287.1    JH431849    GFAC01005763    JAT93425.1    GFPF01007226    MAA18372.1    GEDV01005833    JAP82724.1    GFWV01009093    MAA33822.1    GEFM01002643    JAP73153.1    MG197667    AUG84417.1    GABZ01004227    JAA49298.1    GABZ01004165    JAA49360.1    KB099687    ELK38029.1    JP008686    AER97283.1    AEYP01017478    AEYP01017479    AEYP01017480    AEYP01017481    AEYP01017482    AEYP01017483    AEYP01017484    AEYP01017485    AEYP01017486    AEYP01017487    AAEX03017106    AANG04001815    KE163428    EPQ12035.1    EU375312    ABY81651.1    AFYH01019056    AFYH01019057    AFYH01019058    AFYH01019059    AFYH01019060    AFYH01019061    AFYH01019062    AFYH01019063    AFYH01019064    AFYH01019065    KB030403    ELK17610.1    AMGL01008844    AMGL01008845    AMGL01008846    AMGL01008847    AMGL01008848    AMGL01008849    JH881342    ELR54924.1   

Proteomes

UP000218220    UP000053268    UP000007151    UP000053240    UP000283053    UP000076502    + More
UP000279307    UP000053097    UP000095300    UP000076420    UP000018467    UP000248482    UP000261680    UP000291021    UP000000715    UP000286642    UP000002254    UP000002281    UP000011712    UP000286640    UP000248481    UP000286641    UP000008672    UP000010552    UP000002356    UP000245340   

Pfam

PF00625   Guanylate_kin        + More
PF00595   PDZ
PF00018   SH3_1
PF09058   L27_1
PF07653   SH3_2
PF10600   PDZ_assoc
PF10608   MAGUK_N_PEST

Interpro

IPR036034   PDZ_sf        + More
IPR020590   Guanylate_kinase_CS       
IPR001478   PDZ       
IPR027417   P-loop_NTPase       
IPR036028   SH3-like_dom_sf       
IPR008144   Guanylate_kin-like_dom       
IPR001452   SH3_domain       
IPR008145   GK/Ca_channel_bsu       
IPR036892   L27_dom_sf       
IPR016313   DLG1-like       
IPR004172   L27_dom       
IPR015143   L27_1       
IPR019583   PDZ_assoc       
IPR019590   DLG1_PEST_dom       

SUPFAM

SSF50044   SSF50044        + More
SSF50156   SSF50156       
SSF52540   SSF52540       
SSF101288   SSF101288       

ProteinModelPortal

A0A2A4JR09   A0A2A4JRK4   A0A2H1W7K0   A0A2A4JRB3   A0A0U2HMF0   A0A2A4JR48   + More
A0A2A4JRZ5   A0A194PH93   A0A212FL53   A0A194R1R0   A0A2A4JQD3   A0A2A4JQA2   A0A3S2PLC9   A0A1Y1MJX2   A0A2A4JQH7   A0A1Y1MJV2   V5GV54   F5HSC5   A0A0C9RXG9   V5GR91   V5G281   A0A1Y1MJW0   A0A154P021   A0A0P4VLH1   A0A0V0G9P6   A0A224X883   A0A069DWP4   V5I8P0   A0A1Y1MJV4   A0A3L8DUI6   A0A146LP79   A0A026W6I5   A0A1I8PWD6   A0A1B6K8F3   A0A1B6L875   A0A1B6LX85   T1J4T3   A0A1E1X2C6   A0A224YX20   A0A131YU35   A0A293LYS5   A0A131Y0Z9   A0A2H5BFB1   A0A2C9KA59   A0A2C9KA53   A0A2C9KA56   K9IN98   K9INA8   A0A2C9KA55   A0A3B1JY72   A0A3B1JEF9   L5MHD9   A0A2Y9KH23   A0A2C9KAB4   A0A384DIE7   A0A384DHW2   M1EN05   M3XXD9   A0A3Q7UTC4   A0A384DIF1   F1PCU2   A0A3Q2KRT3   A0A2I2UWT1   A0A2Y9KAM3   A0A3Q7RJX8   A0A3Q7VS47   A0A3Q2I4R1   A0A3Q2IA28   A0A2Y9H9G0   A0A2I2TZZ7   A0A3Q7RLN9   A0A2Y9HF24   A0A3Q2HDR8   A0A3Q2LA49   A0A3Q7PPZ2   A0A3Q7PPV9   A0A2I2V3W9   A0A3Q7SUT2   S7N7F4   A0A337SSR6   A0A3Q7SUT6   A0A3Q7PEQ3   A0A3Q7RKD5   A0A3Q7RVM8   A0A3Q7RLP4   A0A3Q7RJX4   B0LUR1   H3BAN3   L5L2E5   A0A3Q7PPW5   W5QGN5   A0A2U3ZBD9   A0A3Q7WBI5   A0A384DHP6   L8IHB4   A0A3Q2I1P2   A0A3Q7RLN3   A0A3Q7VS56   A0A2Y9HFZ3   A0A2Y9H969  

PDB

2XKX     E-value=2.60552e-171,     Score=1548

KEGG

101744274    K12076 disks large protein 1 | (RefSeq) disks large 1 tumor suppressor protein

GO

GO:0016021   GO:0016301   GO:0044325   GO:0030953   GO:0005783   GO:0098978   GO:0098919   GO:0001935   GO:0032147   GO:0030838   GO:0031594   GO:0008022   GO:0048471   GO:0002088   GO:0048608   GO:0005923   GO:0005874   GO:0072659   GO:0014069   GO:0031253   GO:0008360   GO:0031641   GO:0097025   GO:1903078   GO:0070830   GO:0035748   GO:0000122   GO:1903764   GO:0051898   GO:0016328   GO:0097016   GO:0033268   GO:0045121   GO:0043622   GO:0007015   GO:0030866   GO:0001658   GO:0005794   GO:0043268   GO:0005604   GO:0042982   GO:0045930   GO:0099645   GO:0015459   GO:0009898   GO:0043219   GO:0050680   GO:0001772   GO:0048704   GO:0008284   GO:0042110   GO:0034629   GO:0060022   GO:0001771   GO:0031434   GO:0060090   GO:0016323   GO:0042130   GO:0070373   GO:0048745   GO:0098609   GO:0031579   GO:0051660   GO:0005634   GO:1903753   GO:0002369   GO:0019902   GO:1903760   GO:1903286   GO:0030432   GO:0005515   GO:0005840   GO:0006412   GO:0019843   GO:0005622   GO:0004656   GO:0016702   GO:0016295   GO:0016296  

Length:

713

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

2.51596000000001

Exp number, first 60 AAs:

0.70215

Total prob of N-in:

0.11580

outside

1  -  713

 

 

Pi

193.633138

Theta

168.283075

Tajima's D

0.435109

CLR

0.020159

CSRT

0.496825158742063

Interpretation

Uncertain