Gene

KWMTBOMO07175

Pre Gene Modal

BGIBMGA010561

Annotation

phosphatidylinositol_3-kinase_60_[Bombyx_mori]

Location

Bomo_Chr12(+):7104069-7108323      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 2.288 Nuclear   Reliability : 2.263

CDS

ATGGTCGAAATAGGAGTTCCACAGCAGTCACCAGAACATAGCCTAGAAGCTGCGGAGTGGTACTGGGGCGATATAACAAGAGATGAAGCCAATGAAAAACTTCGAGACACTCGTGATGGAACTTTTCTTGTTCGTAATGCATCTAATAAGGATAGTGGATATACATTGACAGTCAGGAAAGGTGGTGCAAATAAGTTGATCAAAATATACCATCATGAAGGTCGATATGGCTTCCGTGAACCTTTTGAATTTAAGTCAGTAGTTGATCTTGTATGCTATTACAGTGAATACTCCCTGGCAACATGTAACAGTAGTCTAGACATCAAACTCTTGTATCCATTGTCTAGACATCAAGAAAATGAAGGAGGTGAAAACATAAGTGATGAAACTTTAGCAACTAGGTATAAAGAGATACATAAGAAGTATATATTAAAAACTAGGGATTACAATATAAGATTTTCTAAATATACAAGATTAAGGGAAGAAGTTACTTTAAAACGACAAGCTTTAGAAGCGTTTAGAGAAGCTGTAAAAATGTGTGAAGACCACATTAAACTACAAGAAAAAATACAAGCAGAAGCACAGCCTCATGAAAAAAATATAGTCTTGGAAAACAACCGACAGCTCATGGCAAAATTACAAAGTTTGAAACAAGCCAAGGCTGAACTAAGTGAAATCCTGAGGACTACATTAGAATGCAATTTAGTTGTCGAAAGAGATTTAACAAAGTTAAAATCAGATGTAGTAAAGCTCTACAATTTGAAGGATCGCCACAAAATGTGGTTGCAAGGGAGAGGGAAATCTGATGAATATTTAAAAGCTTTAGAGGAGAACAATATTCATAAATTAGATGAAATTAATGCTCATCGTGATATGGACACTTGGAAAGTTAATTGCACCCGGGAGACAGCTGAAAAACTGCTTGCCGGAAAACCACAGGGCACATTCCTGATAAGACCAAATTCTACAGGACAGTTAGCTCTCTCTATTGTCTGTAATAACATGGTCTATCATTGCATTATAAATAAGACTGAATGTGGATATGGTTTTGCTGAACCATACAATATCTACGAAACATTGAATGAATTAGTACTACATTATGCAGGAAATTCATTGGAGGAGCACAATGATCAGTTGAGAACTGAGTTAAAATACCCAGTTAATATGCATCTGGCAAAAAAACCTGAAAAGAATTGA

Protein

MVEIGVPQQSPEHSLEAAEWYWGDITRDEANEKLRDTRDGTFLVRNASNKDSGYTLTVRKGGANKLIKIYHHEGRYGFREPFEFKSVVDLVCYYSEYSLATCNSSLDIKLLYPLSRHQENEGGENISDETLATRYKEIHKKYILKTRDYNIRFSKYTRLREEVTLKRQALEAFREAVKMCEDHIKLQEKIQAEAQPHEKNIVLENNRQLMAKLQSLKQAKAELSEILRTTLECNLVVERDLTKLKSDVVKLYNLKDRHKMWLQGRGKSDEYLKALEENNIHKLDEINAHRDMDTWKVNCTRETAEKLLAGKPQGTFLIRPNSTGQLALSIVCNNMVYHCIINKTECGYGFAEPYNIYETLNELVLHYAGNSLEEHNDQLRTELKYPVNMHLAKKPEKN

Uniprot

B2MW85   E9JEI7   A0A2A4JYY8   A0A194PH65   A0A194R1T3   A0A212EPK6   + More
A0A3S2TDL1   A0A0L7K582   A0A1B6CDR5   A0A2J7QUJ7   A0A1B6LVJ2   A0A0V0GB87   A0A069DX08   A0A023F1S3   A0A0H3W566   A0A1B6FJB3   A0A067QW74   A0A2R7WZ17   V9IIR3   E2B922   A0A0A9YVC8   K7IY25   A0A1L8DKY6   A0A310S655   A0A2A3EMQ0   A0A087ZTP6   A0A0L7RBK7   A0A026W141   A0A2A3ENF5   A0A232FBZ8   A0A0N0BDR0   E9ILF7   A0A3L8DWX7   A0A1Y1KG67   A0A1Y1KD31   A0A154PNQ7   A0A0J7NIY6   A0A195D5D4   F4X2C5   A0A2S2PZ81   E0VYA2   A0A158NJN6   A0A195BBL3   A0A195FNC5   E2ARR6   A0A195EKI9   T1J1N3   A0A151X6I9   J9JPF5   A0A1W5ALS3   A0A1W5AKH5   R7TP28   A0A2H8U1S2   A0A2S2P8K9   A0A1W5ADW3   A0A1A8CRB1   A0A1W4ZIJ2   B0S6V6   J9JXE8   A0A1W4ZHV8   A0A3B3QZV0   A0A1A8QBK6   A0A3Q3ERZ0   A0A3B3R0E5   A0A3Q1F2B0   A0A3B4XXY7   A0A3B4U8S0   A0A3Q2ZIJ4   A0A0T6B9V5   A0A3B3QX85   A0A3Q1CD09   A0A3P8RTX6   A0A3Q2Q6Y5   A0A2I4CPJ9   A0A1W4Z9B3   A0A1A7W9Z1   A0A2H6ND68   A0A3Q2C9S6   A0A3B5Q993   A0A091KBX4   A0A093BWZ0   A0A091LUJ8   A0A087VC22   A0A094KDT5   A0A091JWL0   A0A1S2ZRW3   A0A3B3R1D6   E1C8M4   A0A091RWK6   A0A2I0M1A2   A0A3B5M019   A0A1A8BEU9   A0A1A8KJT7   A0A2I4CPK2   A0A1U7RK29   A0A1W5A8R8   A0A3Q3K8C9   A0A3P8RC63  

Pubmed

20197069    19121390    21040523    26354079    22118469    26227816    + More
26334808    25474469    24845553    20798317    25401762    26823975    20075255    24508170    28648823    21282665    30249741    28004739    21719571    20566863    21347285    23254933    23594743    29240929    23542700    15592404    23371554   

EMBL

EU636066    ACC94001.1    BABH01005657    GQ426304    JQ087868    ADM32530.1    + More
AEY80385.1    NWSH01000345    PCG77227.1    KQ459603    KPI92746.1    KQ460883    KPJ11210.1    AGBW02013442    OWR43430.1    RSAL01000288    RVE42936.1    JTDY01010846    KOB57957.1    GEDC01025878    GEDC01010233    JAS11420.1    JAS27065.1    NEVH01010552    PNF32256.1    GEBQ01012312    JAT27665.1    GECL01000753    JAP05371.1    GBGD01000469    JAC88420.1    GBBI01003250    JAC15462.1    KP635379    AKK23736.1    GECZ01019491    JAS50278.1    KK852886    KDR14361.1    KK856067    PTY24772.1    JR049394    AEY60950.1    GL446425    EFN87788.1    GBHO01010074    GDHC01021167    JAG33530.1    JAP97461.1    GFDF01006955    JAV07129.1    KQ768636    OAD53077.1    KZ288207    PBC33035.1    KQ414617    KOC68223.1    KK107499    EZA49782.1    PBC33034.1    NNAY01000442    OXU28354.1    KQ435851    KOX70804.1    GL764076    EFZ18596.1    QOIP01000003    RLU24802.1    GEZM01087900    JAV58406.1    GEZM01087899    JAV58408.1    KQ434977    KZC12898.1    LBMM01004387    KMQ92475.1    KQ976818    KYN08105.1    GL888575    EGI59407.1    GGMS01001538    MBY70741.1    DS235845    EEB18358.1    ADTU01018090    ADTU01018091    ADTU01018092    ADTU01018093    ADTU01018094    ADTU01018095    KQ976526    KYM81928.1    KQ981424    KYN41827.1    GL442166    EFN63874.1    KQ978782    KYN28384.1    JH431789    KQ982482    KYQ55939.1    ABLF02034706    AMQN01002403    KB309137    ELT95404.1    GFXV01008027    MBW19832.1    GGMR01013170    MBY25789.1    HADZ01018363    SBP82304.1    BX571667    ABLF02021400    HAEH01010832    SBR90717.1    LJIG01009142    KRT83671.1    HADW01000946    HADX01007476    SBP02346.1    IACI01084411    LAA29990.1    KK738976    KFP38064.1    KL449432    KFV04497.1    KK508204    KFP62127.1    KL487691    KFO10164.1    KL254687    KFZ56785.1    KK536441    KFP29552.1    AC186821    KK710105    KFQ32782.1    AKCR02000050    PKK23453.1    HADZ01001225    SBP65166.1    HAEE01012411    SBR32461.1   

Proteomes

UP000005204    UP000218220    UP000053268    UP000053240    UP000007151    UP000283053    + More
UP000037510    UP000235965    UP000027135    UP000008237    UP000002358    UP000242457    UP000005203    UP000053825    UP000053097    UP000215335    UP000053105    UP000279307    UP000076502    UP000036403    UP000078542    UP000007755    UP000009046    UP000005205    UP000078540    UP000078541    UP000000311    UP000078492    UP000075809    UP000007819    UP000192224    UP000014760    UP000000437    UP000261540    UP000261660    UP000257200    UP000261360    UP000261420    UP000264800    UP000257160    UP000265080    UP000265000    UP000192220    UP000265020    UP000002852    UP000079721    UP000000539    UP000053872    UP000261380    UP000189705    UP000261600    UP000265100   

PRIDE

B2MW85    E9JEI7   

Pfam

PF16454   PI3K_P85_iSH2        + More
PF00017   SH2
PF00098   zf-CCHC
PF00076   RRM_1
PF00620   RhoGAP
PF07647   SAM_2
PF00536   SAM_1
PF00130   C1_1
PF07653   SH3_2

Interpro

IPR032498   PI3K_P85_iSH2        + More
IPR036860   SH2_dom_sf       
IPR000980   SH2       
IPR035020   PI3kinase_P85_cSH2       
IPR035022   PI3kinase_P85_nSH2       
IPR000504   RRM_dom       
IPR012677   Nucleotide-bd_a/b_plait_sf       
IPR001878   Znf_CCHC       
IPR035979   RBD_domain_sf       
IPR000198   RhoGAP_dom       
IPR008936   Rho_GTPase_activation_prot       
IPR001660   SAM       
IPR013761   SAM/pointed_sf       
IPR002219   PE/DAG-bd       
IPR001452   SH3_domain       
IPR036028   SH3-like_dom_sf       

SUPFAM

SSF55550   SSF55550        + More
SSF54928   SSF54928       
SSF48350   SSF48350       
SSF47769   SSF47769       
SSF50044   SSF50044       

Gene 3D

3.30.505.10     3.30.70.330     1.10.555.10     1.10.150.50    

CDD

cd09930  SH2_cSH2_p85_like
cd09942  SH2_nSH2_p85_like
cd00029  C1

ProteinModelPortal

B2MW85   E9JEI7   A0A2A4JYY8   A0A194PH65   A0A194R1T3   A0A212EPK6   + More
A0A3S2TDL1   A0A0L7K582   A0A1B6CDR5   A0A2J7QUJ7   A0A1B6LVJ2   A0A0V0GB87   A0A069DX08   A0A023F1S3   A0A0H3W566   A0A1B6FJB3   A0A067QW74   A0A2R7WZ17   V9IIR3   E2B922   A0A0A9YVC8   K7IY25   A0A1L8DKY6   A0A310S655   A0A2A3EMQ0   A0A087ZTP6   A0A0L7RBK7   A0A026W141   A0A2A3ENF5   A0A232FBZ8   A0A0N0BDR0   E9ILF7   A0A3L8DWX7   A0A1Y1KG67   A0A1Y1KD31   A0A154PNQ7   A0A0J7NIY6   A0A195D5D4   F4X2C5   A0A2S2PZ81   E0VYA2   A0A158NJN6   A0A195BBL3   A0A195FNC5   E2ARR6   A0A195EKI9   T1J1N3   A0A151X6I9   J9JPF5   A0A1W5ALS3   A0A1W5AKH5   R7TP28   A0A2H8U1S2   A0A2S2P8K9   A0A1W5ADW3   A0A1A8CRB1   A0A1W4ZIJ2   B0S6V6   J9JXE8   A0A1W4ZHV8   A0A3B3QZV0   A0A1A8QBK6   A0A3Q3ERZ0   A0A3B3R0E5   A0A3Q1F2B0   A0A3B4XXY7   A0A3B4U8S0   A0A3Q2ZIJ4   A0A0T6B9V5   A0A3B3QX85   A0A3Q1CD09   A0A3P8RTX6   A0A3Q2Q6Y5   A0A2I4CPJ9   A0A1W4Z9B3   A0A1A7W9Z1   A0A2H6ND68   A0A3Q2C9S6   A0A3B5Q993   A0A091KBX4   A0A093BWZ0   A0A091LUJ8   A0A087VC22   A0A094KDT5   A0A091JWL0   A0A1S2ZRW3   A0A3B3R1D6   E1C8M4   A0A091RWK6   A0A2I0M1A2   A0A3B5M019   A0A1A8BEU9   A0A1A8KJT7   A0A2I4CPK2   A0A1U7RK29   A0A1W5A8R8   A0A3Q3K8C9   A0A3P8RC63  

PDB

5M6U     E-value=3.98703e-78,     Score=742

KEGG

100158253    K02649 phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | (RefSeq) Pi3k60, pi3k; phosph

GO

GO:0005942   GO:0035014   GO:0016301   GO:0003723   GO:0008270   GO:0007165   GO:0046872   GO:0035556   GO:0046854   GO:0008286   GO:0043551   GO:0046935   GO:0005829  

Length:

398

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.03061

Exp number, first 60 AAs:

0

Total prob of N-in:

0.00485

outside

1  -  398

 

 

Pi

44.186658

Theta

177.797113

Tajima's D

-0.652461

CLR

1.083113

CSRT

0.206489675516224

Interpretation

Uncertain