Gene

KWMTBOMO07146  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010403

Annotation

mitochondrial_aldehyde_dehydrogenase_[Bombyx_mori]

Location

Bomo_Chr12(-):6335678-6348976      View in EpiBrowser

Location in the cell

Cytoplasmic   Reliability : 1.376

CDS

ATGGTGAAAGTAGACGTCAAGTACACTAAGCTATTTATCAACAATGAATGGGTAGATGCTGTCAGCAAAAAAACCTTCCCTACCATCAACCCACAAGATGAAACAGTCATAACACAGGTCGCTGAAGGAGATAAGGCGGATATTGATTTGGCCGTCGCCGCAGCAAAGAAAGCATTCCACCGTTATTCCCCATGGCGTACCATGGACGCTTCTCAACGCGGCCTCCTATTGCTTAAGCTAGCCGAACTTCTAGAATCCCAATCTAGATACCTAGCTGAGCTAGAGACTTTAGACTGTGGAAAACCGGTAAAACAATCCGAAGAAGAAGTATACTTTTCCGCAAGCGTGCTCAGATATTACGCTGGAAAAGCGGACAAGATATTAGGAAATACCATTCCTTCAGACGGAGAAGTCCTTACGTTCACCATGAAGGAGCCTGTCGGAGTGTGCGGTCAGATAATACCGTGGAATTACCCCATACCAATGATGTCTTGGAAAATAGCACCAGCCTTAGCTGCAGGATGTACCGTTGTTCTGAAGCCAGCTGAACAAACACCGCTGACTGCGCTCGCTGTTGCCGCCCTGGTCAAAGAAGCGGGCTTTCCACCGGGGGTTGTCAATGTCGTTCCCGGATACGGTGCGACAGCGGGCGGTGCTCTTACTCACCACCCAGATGTTGACAAAATCGCTTTCACTGGCTCCACTGAGGTATACTTTTTTTCTATTGCTTAG

Protein

MVKVDVKYTKLFINNEWVDAVSKKTFPTINPQDETVITQVAEGDKADIDLAVAAAKKAFHRYSPWRTMDASQRGLLLLKLAELLESQSRYLAELETLDCGKPVKQSEEEVYFSASVLRYYAGKADKILGNTIPSDGEVLTFTMKEPVGVCGQIIPWNYPIPMMSWKIAPALAAGCTVVLKPAEQTPLTALAVAALVKEAGFPPGVVNVVPGYGATAGGALTHHPDVDKIAFTGSTEVYFFSIA

Similarity

Belongs to the aldehyde dehydrogenase family.
Belongs to the protein disulfide isomerase family.

Uniprot

Q2F5Y9   A0A194PHE0   D2SNR7   A0A194R140   A0A194R1V2   A0A2A4JJH0   + More
A0A2H1VX41   A0A0L7LPC3   A0A2H1VID4   A0A212EPN8   A0A212EPE8   D2SNQ8   B0X5Q3   A0A2M4AF40   A0A2M4AEX2   A0A1D2N1N3   A0A1S3IR17   A0A1S3HNG6   T1DF46   A0A182QSK4   A0A182GPP9   A0A1J1HJ07   Q16UC5   A0A023EVW3   A0A182F3L2   A0A1S3HRB3   D6X3U7   A0A1Q3FGB5   A0A1S4FNU3   A7XZK3   F6UAT6   W5JT01   A0A1W7R9T2   G3WMK0   A0A182XHT7   A0A182HRD9   A0A369S0Y8   A0A1S4H2G8   Q7Q165   A0A369S1T2   A0A1J1J3B3   B3RSM9   A0A182KYZ4   A0A182VIA5   A0A1B2YLJ7   A0A2U4CG69   A0A384BC88   A1KXI6   F7C0D1   A0A0N8BST4   A0A2S2R0V2   A0A154P517   A0A3G5AQ09   K1QVG5   A0A2F0B3F8   W4XV28   A0A3G5ANS0   K1R266   A0A3S3NWG2   A0A146N6N5   A0A210Q7D8   A0A1S2ZT62   A0A2Y9QA90   A1KXH7   A0A2Y9FAN7   A0A182U026   A0A1W4X864   V4BLL6   L9L452   A0A2R4A6R7   A0A1I8I940   A0A267EC57   A0A1I8JFG3   C3XVV4   A0A2D0PLT6   A0A146XLL6   A0A2K6EL72   E9IRW6   A0A146XJ16   A0A1U8C9A1   G3H7E6   B3RSM8   A0A3B1K1J7   A0A3B1IZU8   G3V7I5   A0A1A6G234   A0A0P5Y166   A0A287CXM9   A0A1S3JX91   A0A087TDX4   E2AFW0   A0A098M1T5   H0Y163   A0A0P4Z8Q6   A0A2S2PZM6   I3N1D1   E2RHQ0   A0A0P4XW28   V5GV38   A0A1S3HPE0  

Pubmed

19121390    26354079    20074338    26227816    22118469    27289101    + More
26383154    26483478    17510324    24945155    18362917    19820115    18464734    20920257    23761445    21709235    30042472    12364791    18719581    20966253    17495919    22992520    28812685    23254933    23385571    29492455    26392545    18563158    21282665    21804562    25329095    15057822    15632090    20798317    16341006   

EMBL

BABH01005570    BABH01005571    BABH01005572    BABH01005573    DQ311283    ABD36228.1    + More
KQ459603    KPI92727.1    EZ407197    ACX53758.1    KQ460883    KPJ11229.1    KPJ11230.1    NWSH01001358    PCG71550.1    ODYU01004657    SOQ44774.1    JTDY01000429    KOB77219.1    ODYU01002733    SOQ40599.1    AGBW02013442    OWR43436.1    AGBW02013494    OWR43337.1    EZ407188    ACX53749.1    DS232392    EDS41034.1    GGFK01006088    MBW39409.1    GGFK01006020    MBW39341.1    LJIJ01000295    ODM99179.1    GAMD01003251    JAA98339.1    AXCN02000654    JXUM01078869    KQ563093    KXJ74487.1    CVRI01000006    CRK88023.1    CH477625    EAT38124.1    GAPW01001149    JAC12449.1    KQ971326    EEZ97369.1    GFDL01008464    JAV26581.1    EU106624    ABU97475.1    ADMH02000539    ETN66060.1    GFAH01000487    JAV47902.1    AEFK01074650    APCN01001694    NOWV01000103    RDD40389.1    AAAB01008980    EAA14068.3    RDD40374.1    CVRI01000066    CRL06284.1    DS985243    EDV26543.1    KX060612    AOD75396.1    AY291328    AAQ24547.1    GDIQ01148387    JAL03339.1    GGMS01014351    MBY83554.1    KQ434820    KZC07026.1    MH979760    AYV89215.1    JH817012    EKC37583.1    NTJE010061653    MBV97550.1    AAGJ04009886    AAGJ04009887    MH990439    AYV88986.1    EKC37584.1    NCKU01002086    RWS10468.1    GCES01158808    JAQ27514.1    NEDP02004706    OWF44662.1    AY283296    AAP35081.1    KB202567    ESO89599.1    KB320515    ELW69851.1    KY679131    AVR59242.1    NIVC01002449    PAA57759.1    NIVC01002372    PAA58467.1    NIVC01000222    PAA87659.1    GG666469    EEN67897.1    GCES01044211    JAR42112.1    GL765283    EFZ16677.1    GCES01044212    JAR42111.1    JH000194    EGW07916.1    EDV26544.1    AC133299    CH473962    EDL98822.1    LZPO01107946    OBS59865.1    GDIP01066067    JAM37648.1    AGTP01043698    KK114785    KFM63313.1    GL439158    EFN67709.1    GBSI01000206    JAC96289.1    AAQR03033261    GDIP01220392    JAJ03010.1    GGMS01001617    MBY70820.1    AAEX03007973    GDIP01238190    JAI85211.1    GALX01004368    JAB64098.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000218220    UP000037510    UP000007151    + More
UP000002320    UP000094527    UP000085678    UP000075886    UP000069940    UP000249989    UP000183832    UP000008820    UP000069272    UP000007266    UP000002279    UP000000673    UP000007648    UP000076407    UP000075840    UP000253843    UP000007062    UP000009022    UP000075882    UP000075903    UP000245320    UP000261681    UP000002280    UP000076502    UP000005408    UP000007110    UP000285301    UP000242188    UP000079721    UP000248483    UP000248484    UP000075902    UP000192223    UP000030746    UP000011518    UP000095280    UP000215902    UP000001554    UP000221080    UP000233160    UP000189706    UP000001075    UP000018467    UP000002494    UP000092124    UP000005215    UP000054359    UP000000311    UP000005225    UP000002254   

PRIDE

Q2F5Y9    B3RSM9    K1QVG5    K1R266    G3H7E6    B3RSM8    + More

Pfam

PF00171   Aldedh        + More
PF00085   Thioredoxin

Interpro

IPR016161   Ald_DH/histidinol_DH        + More
IPR016163   Ald_DH_C       
IPR016160   Ald_DH_CS_CYS       
IPR029510   Ald_DH_CS_GLU       
IPR016162   Ald_DH_N       
IPR015590   Aldehyde_DH_dom       
IPR036249   Thioredoxin-like_sf       
IPR005788   Disulphide_isomerase       
IPR013766   Thioredoxin_domain       
IPR017937   Thioredoxin_CS       

SUPFAM

SSF53720   SSF53720        + More
SSF52833   SSF52833       

Gene 3D

3.40.309.10     3.40.605.10    

ProteinModelPortal

Q2F5Y9   A0A194PHE0   D2SNR7   A0A194R140   A0A194R1V2   A0A2A4JJH0   + More
A0A2H1VX41   A0A0L7LPC3   A0A2H1VID4   A0A212EPN8   A0A212EPE8   D2SNQ8   B0X5Q3   A0A2M4AF40   A0A2M4AEX2   A0A1D2N1N3   A0A1S3IR17   A0A1S3HNG6   T1DF46   A0A182QSK4   A0A182GPP9   A0A1J1HJ07   Q16UC5   A0A023EVW3   A0A182F3L2   A0A1S3HRB3   D6X3U7   A0A1Q3FGB5   A0A1S4FNU3   A7XZK3   F6UAT6   W5JT01   A0A1W7R9T2   G3WMK0   A0A182XHT7   A0A182HRD9   A0A369S0Y8   A0A1S4H2G8   Q7Q165   A0A369S1T2   A0A1J1J3B3   B3RSM9   A0A182KYZ4   A0A182VIA5   A0A1B2YLJ7   A0A2U4CG69   A0A384BC88   A1KXI6   F7C0D1   A0A0N8BST4   A0A2S2R0V2   A0A154P517   A0A3G5AQ09   K1QVG5   A0A2F0B3F8   W4XV28   A0A3G5ANS0   K1R266   A0A3S3NWG2   A0A146N6N5   A0A210Q7D8   A0A1S2ZT62   A0A2Y9QA90   A1KXH7   A0A2Y9FAN7   A0A182U026   A0A1W4X864   V4BLL6   L9L452   A0A2R4A6R7   A0A1I8I940   A0A267EC57   A0A1I8JFG3   C3XVV4   A0A2D0PLT6   A0A146XLL6   A0A2K6EL72   E9IRW6   A0A146XJ16   A0A1U8C9A1   G3H7E6   B3RSM8   A0A3B1K1J7   A0A3B1IZU8   G3V7I5   A0A1A6G234   A0A0P5Y166   A0A287CXM9   A0A1S3JX91   A0A087TDX4   E2AFW0   A0A098M1T5   H0Y163   A0A0P4Z8Q6   A0A2S2PZM6   I3N1D1   E2RHQ0   A0A0P4XW28   V5GV38   A0A1S3HPE0  

PDB

1AG8     E-value=1.50898e-62,     Score=605

KEGG

692889    K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] | (RefSeq) mitochondrial aldehyde dehydrogenase

PATHWAY

00010    Glycolysis / Gluconeogenesis - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00071    Fatty acid degradation - Bombyx mori (domestic silkworm)
00280    Valine, leucine and isoleucine degradation - Bombyx mori (domestic silkworm)
00310    Lysine degradation - Bombyx mori (domestic silkworm)
00330    Arginine and proline metabolism - Bombyx mori (domestic silkworm)
00340    Histidine metabolism - Bombyx mori (domestic silkworm)
00380    Tryptophan metabolism - Bombyx mori (domestic silkworm)
00410    beta-Alanine metabolism - Bombyx mori (domestic silkworm)
00561    Glycerolipid metabolism - Bombyx mori (domestic silkworm)
00620    Pyruvate metabolism - Bombyx mori (domestic silkworm)
00981    Insect hormone biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016620   GO:0016491   GO:0004029   GO:0005654   GO:0005739   GO:0045454   GO:0016853   GO:0005623   GO:0008152   GO:0005515   GO:0031032   GO:0030060   GO:0019752   GO:0016295   GO:0016296   GO:0055114  

Length:

243

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.18131

Exp number, first 60 AAs:

0

Total prob of N-in:

0.27851

outside

1  -  243

 

 

Pi

215.558087

Theta

165.10144

Tajima's D

0.502949

CLR

0.837497

CSRT

0.512624368781561

Interpretation

Uncertain