Gene

KWMTBOMO07132  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010546

Annotation

prophenol_oxidase_activating_enzyme_precursor_[Manduca_sexta]

Location

Bomo_Chr12(+):5914392-5929141      View in EpiBrowser

Location in the cell

Extracellular   Reliability : 4.475

CDS

ATGAGGAATAAAGTGTTGTTGCTTGTGTCGTCGCTTTTTTGGAGCTATGTTCTTTCAGATCATTGCACGACGCCGCTCGGCGAAGCTAGCGAATGCGTCTCATTGTACGATTGCTCTCAACTGTTGTCTGCGTTCGAGCAACGGCCCTTACAAAGCAAAGTGGTCAGCTTCCTGAGACAATCACAATGTGGTTTTCAGGGATACGTACCGAGAGTTTGTTGTGGGCCTTTACCGGCGCAACAAGAGAGGCAGACTACGCCACGCTCAAGAACAACGCGGCCTCCGACGAATGTGGTCGGCCACGTCGACCCCACAGTGCCAGAAGACTCGTCCCCAGCTCCTCGGAATCAATGCGGAGTGGACACACAAGGTGACAGAATCTATGGGGGTCAGTTCACGGACTTAGATGAATTTCCTTGGATGGCTTTGCTTGGATATCTGACGAGTAGGAATACCATAACCTATCAATGCGGCGGTGTGCTCTTCAACGCCCGCTACGTGCTAACGGCTGCTCATTGTTTGATCGGTGCAATCGAAAAGGAAGTCGGTAAATTATAA

Protein

MRNKVLLLVSSLFWSYVLSDHCTTPLGEASECVSLYDCSQLLSAFEQRPLQSKVVSFLRQSQCGFQGYVPRVCCGPLPAQQERQTTPRSRTTRPPTNVVGHVDPTVPEDSSPAPRNQCGVDTQGDRIYGGQFTDLDEFPWMALLGYLTSRNTITYQCGGVLFNARYVLTAAHCLIGAIEKEVGKL

Similarity

Belongs to the peptidase S1 family.

Uniprot

H9JLZ4   O77102   Q5DI99   A0A290U615   D5LPT4   I4DJ03   + More
I4DN03   B3F5B1   A0A2A4JQA1   Q49QW1   A0A173GPF2   A0A0U1WT79   A0A212EKT5   A0A2H1V1Q2   A0A3S2M731   A0A194PP07   S4PK70   Q0VJV8   A0A194R0R2   V5G713   A0A0L7LLI6   F5HKX0   F4YJV1   A0A182HUC7   B1B5K1   J3JYT9   A0A154P5I7   N6TWW7   T1DTQ9   A0A2C9GLQ9   U4U606   A0A1S4HBZ1   A0A023EQB0   J3JXM3   W5JAY3   A0A182V2E3   A0A182LC02   A0A1W7R8M0   A0A336LMT0   A0A182TDG9   A0A182N6J8   A0A0K8VA86   A0A1W4XI92   U4USQ8   A0A182FAQ9   A0A182JX59   A0A0M9A7E2   A0A0K8WFT7   A0A182QUT5   A0A034V075   A0A0K8VB28   A0A067QHJ6   A0A182RLA4   A0A1Q3FC89   A0A0A1WGL4   A0A182XVS0   B0WA88   A0A182LWY5   A0A1J1I303   B4N8B1   A0A182ISD4   A0A084VDB9   A0A1Q3FEM6   A0A1B0FQW4   A0A1A9VW86   A0A1B0BD68   Q17EX4   A0A1A9X740   A0A1A9Z167   B0XAK3   A0A1Y1LC92   A0A154P3E5   A0A1Q3FC43   A0A232EZG2   A0A2J7Q299   Q6BD14   W8BLL3   A0A0C9QZC0   A0A0L7QXF0   B4M4J5   A0A2J7Q278   A0A1A9W879   A0A2P8YP04   A0A1Y1LA48   A0A1Y1LA41   A0A1V1G586   E0VXK9   A0A2J7Q286   B4QZQ4   K7J980   B4I4W4   B4PRF7   A0A182JMK2   Q6Y2X4   Q5DI98   A0A310SR39   A0A2M4AVL9   A0A182QL12   A0A1L8DQN9  

Pubmed

19121390    9770467    15857768    18207075    28953952    22651552    + More
19557749    22118469    26354079    23622113    26227816    12364791    14747013    17210077    18195005    22516182    23537049    24945155    20920257    23761445    20966253    25348373    24845553    25830018    25244985    17994087    24438588    17510324    28004739    28648823    15579698    24495485    29403074    28410430    20566863    20075255    17550304    14505699    16033436   

EMBL

BABH01005537    BABH01005538    AF059728    AAC64004.1    AY789465    AM293327    + More
AAX18636.1    CAL25132.1    KY680243    ATD13324.1    GU953224    ADF43208.1    AK401271    BAM17893.1    AK402671    BAM19293.1    EF614332    ABU98654.1    NWSH01000833    PCG73946.1    AY677081    AAW24480.1    KT006136    ANH58161.1    JQ581597    AFX82593.1    AGBW02014220    OWR42068.1    ODYU01000283    SOQ34775.1    RSAL01000017    RVE52975.1    KQ459603    KPI92860.1    GAIX01004665    JAA87895.1    AM293316    CAL25121.1    KQ460883    KPJ11099.1    GALX01002586    JAB65880.1    JTDY01000666    KOB76290.1    AAAB01008879    EGK96931.1    HM070255    ADZ72972.1    APCN01000619    AB363980    BAG14262.2    BT128420    AEE63377.1    KQ434809    KZC06390.1    APGK01057809    KB741282    ENN70807.1    GAMD01000809    JAB00782.1    KB631684    ERL85365.1    GAPW01001836    JAC11762.1    BT127992    AEE62954.1    ADMH02001903    ETN60568.1    GEHC01000168    JAV47477.1    UFQT01000091    SSX19534.1    GDHF01016430    JAI35884.1    KB632345    ERL93135.1    KQ435719    KOX78755.1    GDHF01002415    JAI49899.1    AXCN02000286    GAKP01023416    JAC35542.1    GDHF01016160    JAI36154.1    KK853628    KDR03824.1    GFDL01009851    JAV25194.1    GBXI01016739    GBXI01006351    JAC97552.1    JAD07941.1    DS231869    EDS40917.1    AXCM01000870    CVRI01000039    CRK94579.1    CH964232    EDW81362.1    ATLV01011243    ATLV01011244    ATLV01011245    ATLV01011246    KE524657    KFB35963.1    GFDL01009047    JAV25998.1    CCAG010023843    JXJN01012354    CH477278    EAT45085.1    DS232586    EDS43739.1    GEZM01061361    GEZM01061358    GEZM01061351    JAV70518.1    KZC06391.1    GFDL01009899    JAV25146.1    NNAY01001477    OXU23832.1    NEVH01019373    PNF22708.1    AY665377    AAT76544.1    GAMC01016016    JAB90539.1    GBYB01001065    JAG70832.1    KQ414704    KOC63285.1    CH940652    EDW59556.1    PNF22686.1    PYGN01000457    PSN45975.1    GEZM01061360    JAV70519.1    GEZM01061363    JAV70514.1    FX985343    BAX07356.1    DS235833    EEB18115.1    PNF22687.1    CM000364    EDX12012.1    AAZX01002213    CH480821    EDW55257.1    CM000160    EDW96345.1    AY188445    AAO74570.1    AH014670    AY789466    AAX18637.1    KQ761039    OAD58341.1    GGFK01011500    MBW44821.1    AXCN02000165    GFDF01005424    JAV08660.1   

Proteomes

UP000005204    UP000218220    UP000007151    UP000283053    UP000053268    UP000053240    + More
UP000037510    UP000007062    UP000075840    UP000076502    UP000019118    UP000030742    UP000000673    UP000075903    UP000075882    UP000075902    UP000075884    UP000192223    UP000069272    UP000075881    UP000053105    UP000075886    UP000027135    UP000075900    UP000076408    UP000002320    UP000075883    UP000183832    UP000007798    UP000075880    UP000030765    UP000092444    UP000078200    UP000092460    UP000008820    UP000092443    UP000092445    UP000215335    UP000235965    UP000053825    UP000008792    UP000091820    UP000245037    UP000009046    UP000000304    UP000002358    UP000001292    UP000002282   

PRIDE

H9JLZ4   

Pfam

PF00089   Trypsin        + More
PF12032   CLIP
PF13019   Sde2_N_Ubi

Interpro

IPR001314   Peptidase_S1A        + More
IPR009003   Peptidase_S1_PA       
IPR018114   TRYPSIN_HIS       
IPR022700   CLIP       
IPR038565   CLIP_sf       
IPR001254   Trypsin_dom       
IPR033116   TRYPSIN_SER       
IPR029071   Ubiquitin-like_domsf       
IPR024974   Sde2_N       

SUPFAM

SSF50494   SSF50494        + More
SSF54236   SSF54236       

Gene 3D

2.20.20.90    

CDD

cd00190  Tryp_SPc

ProteinModelPortal

H9JLZ4   O77102   Q5DI99   A0A290U615   D5LPT4   I4DJ03   + More
I4DN03   B3F5B1   A0A2A4JQA1   Q49QW1   A0A173GPF2   A0A0U1WT79   A0A212EKT5   A0A2H1V1Q2   A0A3S2M731   A0A194PP07   S4PK70   Q0VJV8   A0A194R0R2   V5G713   A0A0L7LLI6   F5HKX0   F4YJV1   A0A182HUC7   B1B5K1   J3JYT9   A0A154P5I7   N6TWW7   T1DTQ9   A0A2C9GLQ9   U4U606   A0A1S4HBZ1   A0A023EQB0   J3JXM3   W5JAY3   A0A182V2E3   A0A182LC02   A0A1W7R8M0   A0A336LMT0   A0A182TDG9   A0A182N6J8   A0A0K8VA86   A0A1W4XI92   U4USQ8   A0A182FAQ9   A0A182JX59   A0A0M9A7E2   A0A0K8WFT7   A0A182QUT5   A0A034V075   A0A0K8VB28   A0A067QHJ6   A0A182RLA4   A0A1Q3FC89   A0A0A1WGL4   A0A182XVS0   B0WA88   A0A182LWY5   A0A1J1I303   B4N8B1   A0A182ISD4   A0A084VDB9   A0A1Q3FEM6   A0A1B0FQW4   A0A1A9VW86   A0A1B0BD68   Q17EX4   A0A1A9X740   A0A1A9Z167   B0XAK3   A0A1Y1LC92   A0A154P3E5   A0A1Q3FC43   A0A232EZG2   A0A2J7Q299   Q6BD14   W8BLL3   A0A0C9QZC0   A0A0L7QXF0   B4M4J5   A0A2J7Q278   A0A1A9W879   A0A2P8YP04   A0A1Y1LA48   A0A1Y1LA41   A0A1V1G586   E0VXK9   A0A2J7Q286   B4QZQ4   K7J980   B4I4W4   B4PRF7   A0A182JMK2   Q6Y2X4   Q5DI98   A0A310SR39   A0A2M4AVL9   A0A182QL12   A0A1L8DQN9  

PDB

2OLG     E-value=3.88053e-13,     Score=177

KEGG

101739185    no KO assigned | (RefSeq) serine protease easter-like

GO

GO:0004252   GO:0008236   GO:0005615   GO:0006508   GO:0016021   GO:0035006   GO:0035008   GO:0006468   GO:0005515   GO:0031032   GO:0030060   GO:0019752   GO:0016491   GO:0016295   GO:0016296  

SignalP

Position:   1 - 19,         Likelihood:  0.996506

 

 

Length:

185

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.58247

Exp number, first 60 AAs:

0.1316

Total prob of N-in:

0.08462

outside

1  -  185

 

 

Pi

193.427763

Theta

148.393119

Tajima's D

0.632672

CLR

0.659873

CSRT

0.55777211139443

Interpretation

Uncertain