SGID Silkworm Genome Informatics Database
Gene
KWMTBOMO07127  Validated by peptides from experiments
Pre Gene Modal
BGIBMGA010544
Annotation
muscular_protein_20_[Bombyx_mori]
Full name
Transgelin       + More
Calponin      
Location in the cell
Cytoplasmic   Reliability : 3.153
 

Sequence

CDS
ATGGGTACTGATGGTGATGGGATGATTCTGTGCGCTGGTAAACGCGAACCAGAAAAAGAGGCAGAAGCTCAACGGTGGATTGAATCGGTTATCGGTGAGCGGTTCCCTTCCGACCTTCCCTACGAGCTGGCTCTCCGTGACGGCATCATCCTTTGCAAGTTGATGAACAGACTCCAACCCGGTATTATTCCTAAAGTCAACATCTCTGGGGGAGACTACAAGTTCATGGATAACATCAGCCAATTCCAAAAGGCTTGCATCAAATATGGTGTGCCCGATGTCGACCTTTTCCAAACTACGGATTTGTGGGATCAAAAGAATATCGTATTAGTCACACAGACTATTTTTGCTATTGGTAGAACGGCATACAAACACCCGGAATGGCGCGGCCCCTTCCTCGGACCCAAGCCTGCTGAAGAAAACAAACGTGCCTTCAGCGAGGATGTTCTTCGAGCTGGGGAGTCCGTCATCGGTCTTCAGGCTGGTACAAACAAGTTGGCCTCACAGTCTGGACAAAACTTTGGAGCCTCGCGTAAAATTATTCTTGGGAAGTAA
Protein
MGTDGDGMILCAGKREPEKEAEAQRWIESVIGERFPSDLPYELALRDGIILCKLMNRLQPGIIPKVNISGGDYKFMDNISQFQKACIKYGVPDVDLFQTTDLWDQKNIVLVTQTIFAIGRTAYKHPEWRGPFLGPKPAEENKRAFSEDVLRAGESVIGLQAGTNKLASQSGQNFGASRKIILGK

Summary

Description
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Similarity
Belongs to the calponin family.
EMBL
BABH01005517    DQ443297    ABF51386.1    AGBW02014220    OWR42073.1    KQ460883    + More
KPJ11093.1    AK401190    BAM17812.1    GDQN01000140    JAT90914.1    KQ459603    KPI92866.1    ODYU01000893    SOQ36338.1    NWSH01000479    PCG76100.1    KB632375    ERL94046.1    KQ971312    EEZ98617.2    DS235271    EEB14245.1    LJIG01022630    KRT79540.1    GDAI01002406    JAI15197.1    GDKW01000614    JAI55981.1    ACPB03021937    GAHY01001414    JAA76096.1    GFDF01000124    JAV13960.1    GBBI01000973    JAC17739.1    GECL01000932    JAP05192.1    GDHC01004850    JAQ13779.1    GGMS01012317    MBY81520.1    GBHO01033576    JAG10028.1    GDHC01019252    GDHC01015403    GDHC01011726    JAP99376.1    JAQ03226.1    JAQ06903.1    PYGN01000567    PSN44120.1    GBRD01002202    GDHC01018630    GDHC01013389    GDHC01004529    GDHC01002200    JAG63619.1    JAP99998.1    JAQ05240.1    JAQ14100.1    JAQ16429.1    GEZM01054387    JAV73704.1    KQ767877    OAD53285.1    GBYB01011321    JAG81088.1    QOIP01000009    RLU18613.1    GFTR01003019    JAW13407.1    GBGD01003137    JAC85752.1    KZ288199    PBC33640.1    GEDC01029198    JAS08100.1    AXCM01001684    ADTU01005844    ADTU01005845    APCN01000983    DS232004    EDS31402.1    ABLF02028983    AK340028    BAH70703.1    AAAB01008847    EAA06856.5    GAMD01003385    JAA98205.1    CH477498    EAT39932.1    GFDL01003449    JAV31596.1    AAZX01000587    AAZX01005616    AAZX01013887    AAZX01022014    KQ982691    KYQ52103.1    AXCN02001455    GEBQ01029147    JAT10830.1    UFQT01000629    SSX25890.1    UFQS01001396    UFQT01001396    SSX10677.1    SSX30359.1    GEMB01002241    JAS00939.1    NNAY01000654    OXU27163.1    GEBQ01011078    JAT28899.1    JXUM01003713    JXUM01003714    JXUM01003715    JXUM01003716    JXUM01003717    KQ560162    KXJ84091.1    KQ414688    KOC63712.1    EF070497    ABM55563.1    APGK01025801    APGK01025802    APGK01025803    APGK01025804    APGK01025805    KB740603    ENN80080.1    KQ971338    EFA01574.1    GFDL01006588    JAV28457.1    CVRI01000073    CRL07706.1    KQ977141    KYN05412.1    GDKW01000577    JAI56018.1    ACPB03002842    GAHY01000760    JAA76750.1    GL447755    EFN86047.1    AXCM01005696    APCN01003291    DS235814    EEB17495.1    LNIX01000008    OXA50648.1    LJIJ01000067    ODN03617.1    AXCN02001041    AAAB01008986    EAA00381.4    ATLV01023888    KE525347    KFB49782.1    DS232012    EDS31822.1    KQ981572    KYN39774.1    EF638975    ABR27860.1    GEMB01002240    JAS00940.1    KQ760498    OAD60090.1    JRES01001157    KNC25114.1    LRGB01000725    KZS16249.1    GEDC01020038    JAS17260.1    GDIP01153400    JAJ70002.1   
Pfam
PF00307   CH        + More
PF00402   Calponin
PF13281   DUF4071
PF00069   Pkinase
Interpro
IPR036872   CH_dom_sf        + More
IPR001715   CH-domain       
IPR003096   SM22_calponin       
IPR000557   Calponin_repeat       
IPR001997   Calponin/LIMCH1       
IPR000719   Prot_kinase_dom       
IPR013761   SAM/pointed_sf       
IPR025136   DUF4071       
IPR017441   Protein_kinase_ATP_BS       
IPR008271   Ser/Thr_kinase_AS       
IPR011009   Kinase-like_dom_sf       
SUPFAM
SSF47576   SSF47576        + More
SSF56112   SSF56112       
SSF47769   SSF47769       
Gene 3D
PDB
1WYN     E-value=1.13193e-19,     Score=233

Ontologies

Topology

Length:
184
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.003
Exp number, first 60 AAs:
0
Total prob of N-in:
0.04213
outside
1  -  184
 
 

Population Genetic Test Statistics

Pi
130.786201
Theta
119.906725
Tajima's D
-0.162035
CLR
23.452046
CSRT
0.328133593320334
Interpretation
Uncertain

Multiple alignment of Orthologues

 
 

Gene Tree

 
 
Peptides ×
Source Sequence Identity Evalue
28556443 VNISGGDYK 100.00 0.016
28556443 VPESINFPAEEDK 100.00 0.016
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