Gene

KWMTBOMO07127  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010544

Annotation

muscular_protein_20_[Bombyx_mori]

Location

Bomo_Chr12(+):5618743-5620315      View in EpiBrowser

Full name

Transgelin       + More
Calponin      

Location in the cell

Cytoplasmic   Reliability : 3.153

CDS

ATGGGTACTGATGGTGATGGGATGATTCTGTGCGCTGGTAAACGCGAACCAGAAAAAGAGGCAGAAGCTCAACGGTGGATTGAATCGGTTATCGGTGAGCGGTTCCCTTCCGACCTTCCCTACGAGCTGGCTCTCCGTGACGGCATCATCCTTTGCAAGTTGATGAACAGACTCCAACCCGGTATTATTCCTAAAGTCAACATCTCTGGGGGAGACTACAAGTTCATGGATAACATCAGCCAATTCCAAAAGGCTTGCATCAAATATGGTGTGCCCGATGTCGACCTTTTCCAAACTACGGATTTGTGGGATCAAAAGAATATCGTATTAGTCACACAGACTATTTTTGCTATTGGTAGAACGGCATACAAACACCCGGAATGGCGCGGCCCCTTCCTCGGACCCAAGCCTGCTGAAGAAAACAAACGTGCCTTCAGCGAGGATGTTCTTCGAGCTGGGGAGTCCGTCATCGGTCTTCAGGCTGGTACAAACAAGTTGGCCTCACAGTCTGGACAAAACTTTGGAGCCTCGCGTAAAATTATTCTTGGGAAGTAA

Protein

MGTDGDGMILCAGKREPEKEAEAQRWIESVIGERFPSDLPYELALRDGIILCKLMNRLQPGIIPKVNISGGDYKFMDNISQFQKACIKYGVPDVDLFQTTDLWDQKNIVLVTQTIFAIGRTAYKHPEWRGPFLGPKPAEENKRAFSEDVLRAGESVIGLQAGTNKLASQSGQNFGASRKIILGK

Description

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Similarity

Belongs to the calponin family.

Uniprot

H9JLZ2   Q1HPV5   A0A212EKR3   A0A194QZX4   I4DIS2   A0A1E1WVB8   + More
A0A194PHH6   A0A2H1V681   A0A2A4JXF1   U4UUZ4   D6WAC0   E0VLI9   A0A0T6AX20   A0A0K8TLG6   A0A0P4VTX0   R4FN73   A0A1L8E5D4   A0A023F9Q8   A0A0V0GBP3   A0A146M2X6   A0A2S2QVJ5   A0A0A9WU71   A0A146KWD1   A0A2P8YIN1   A0A0K8TDN8   A0A1Y1LJ60   A0A310SGA0   A0A0C9RUN3   A0A3L8DEN0   A0A224XLQ5   A0A069DQ56   A0A2A3EPL8   A0A1B6C4D7   A0A182V3S7   A0A182J308   A0A182RL60   A0A182M3C3   A0A158P168   A0A182NAF2   A0A182W488   A0A182PTE6   A0A182FMN3   A0A182I9H7   B0WN00   A0A182XEM4   C4WS33   Q7QEA4   T1DMW5   Q16Z48   A0A1Q3FVV4   K7IXB0   A0A151WW43   A0A182QUX7   A0A1B6KHA6   A0A336M787   A0A336L172   A0A161MQM7   A0A232F9Q3   A0A1B6LYX6   A0A1W4XHX6   A0A182H1U0   A0A0L7QYT5   A2I3Z4   N6UEE5   D2A180   A0A1Q3FLN3   A0A1J1J6U8   A0A195CXV5   A0A0P4VTZ7   R4G571   A0A182PBS6   E2BE60   A0A182XNC2   A0A182MAK6   A0A182HQ43   E0VVT9   A0A226E072   A0A1D2NEF4   A0A182IRI7   A0A182QPI1   A0A182U829   A0A182KSL8   Q7PV70   A0A084WHT8   B0WNJ5   A0A182Y1R8   A0A151JXA4   A0A182JST8   A6YPG4   A0A170ZG36   A0A310ST38   A0A182W947   A0A182T139   A0A0L0C0X0   A0A182R5D1   A0A182VAB4   A0A164ZE12   K7J2Y6   A0A1B6CUU6   A0A0P5DNT9  

Pubmed

19121390    22118469    26354079    22651552    23537049    18362917    + More
19820115    20566863    26369729    27129103    25474469    26823975    25401762    29403074    28004739    30249741    26334808    21347285    12364791    14747013    17210077    17510324    20075255    28648823    26483478    20798317    27289101    20966253    24438588    25244985    18207082    26108605   

EMBL

BABH01005517    DQ443297    ABF51386.1    AGBW02014220    OWR42073.1    KQ460883    + More
KPJ11093.1    AK401190    BAM17812.1    GDQN01000140    JAT90914.1    KQ459603    KPI92866.1    ODYU01000893    SOQ36338.1    NWSH01000479    PCG76100.1    KB632375    ERL94046.1    KQ971312    EEZ98617.2    DS235271    EEB14245.1    LJIG01022630    KRT79540.1    GDAI01002406    JAI15197.1    GDKW01000614    JAI55981.1    ACPB03021937    GAHY01001414    JAA76096.1    GFDF01000124    JAV13960.1    GBBI01000973    JAC17739.1    GECL01000932    JAP05192.1    GDHC01004850    JAQ13779.1    GGMS01012317    MBY81520.1    GBHO01033576    JAG10028.1    GDHC01019252    GDHC01015403    GDHC01011726    JAP99376.1    JAQ03226.1    JAQ06903.1    PYGN01000567    PSN44120.1    GBRD01002202    GDHC01018630    GDHC01013389    GDHC01004529    GDHC01002200    JAG63619.1    JAP99998.1    JAQ05240.1    JAQ14100.1    JAQ16429.1    GEZM01054387    JAV73704.1    KQ767877    OAD53285.1    GBYB01011321    JAG81088.1    QOIP01000009    RLU18613.1    GFTR01003019    JAW13407.1    GBGD01003137    JAC85752.1    KZ288199    PBC33640.1    GEDC01029198    JAS08100.1    AXCM01001684    ADTU01005844    ADTU01005845    APCN01000983    DS232004    EDS31402.1    ABLF02028983    AK340028    BAH70703.1    AAAB01008847    EAA06856.5    GAMD01003385    JAA98205.1    CH477498    EAT39932.1    GFDL01003449    JAV31596.1    AAZX01000587    AAZX01005616    AAZX01013887    AAZX01022014    KQ982691    KYQ52103.1    AXCN02001455    GEBQ01029147    JAT10830.1    UFQT01000629    SSX25890.1    UFQS01001396    UFQT01001396    SSX10677.1    SSX30359.1    GEMB01002241    JAS00939.1    NNAY01000654    OXU27163.1    GEBQ01011078    JAT28899.1    JXUM01003713    JXUM01003714    JXUM01003715    JXUM01003716    JXUM01003717    KQ560162    KXJ84091.1    KQ414688    KOC63712.1    EF070497    ABM55563.1    APGK01025801    APGK01025802    APGK01025803    APGK01025804    APGK01025805    KB740603    ENN80080.1    KQ971338    EFA01574.1    GFDL01006588    JAV28457.1    CVRI01000073    CRL07706.1    KQ977141    KYN05412.1    GDKW01000577    JAI56018.1    ACPB03002842    GAHY01000760    JAA76750.1    GL447755    EFN86047.1    AXCM01005696    APCN01003291    DS235814    EEB17495.1    LNIX01000008    OXA50648.1    LJIJ01000067    ODN03617.1    AXCN02001041    AAAB01008986    EAA00381.4    ATLV01023888    KE525347    KFB49782.1    DS232012    EDS31822.1    KQ981572    KYN39774.1    EF638975    ABR27860.1    GEMB01002240    JAS00940.1    KQ760498    OAD60090.1    JRES01001157    KNC25114.1    LRGB01000725    KZS16249.1    GEDC01020038    JAS17260.1    GDIP01153400    JAJ70002.1   

Proteomes

UP000005204    UP000007151    UP000053240    UP000053268    UP000218220    UP000030742    + More
UP000007266    UP000009046    UP000015103    UP000245037    UP000279307    UP000242457    UP000075903    UP000075880    UP000075900    UP000075883    UP000005205    UP000075884    UP000075920    UP000075885    UP000069272    UP000075840    UP000002320    UP000076407    UP000007819    UP000007062    UP000008820    UP000002358    UP000075809    UP000075886    UP000215335    UP000192223    UP000069940    UP000249989    UP000053825    UP000019118    UP000183832    UP000078542    UP000008237    UP000198287    UP000094527    UP000075902    UP000075882    UP000030765    UP000076408    UP000078541    UP000075881    UP000075901    UP000037069    UP000076858   

PRIDE

H9JLZ2    Q1HPV5   

Pfam

PF00307   CH        + More
PF00402   Calponin
PF13281   DUF4071
PF00069   Pkinase

Interpro

IPR036872   CH_dom_sf        + More
IPR001715   CH-domain       
IPR003096   SM22_calponin       
IPR000557   Calponin_repeat       
IPR001997   Calponin/LIMCH1       
IPR000719   Prot_kinase_dom       
IPR013761   SAM/pointed_sf       
IPR025136   DUF4071       
IPR017441   Protein_kinase_ATP_BS       
IPR008271   Ser/Thr_kinase_AS       
IPR011009   Kinase-like_dom_sf       

SUPFAM

SSF47576   SSF47576        + More
SSF56112   SSF56112       
SSF47769   SSF47769       

Gene 3D

1.10.418.10    

CDD

cd00014  CH

ProteinModelPortal

H9JLZ2   Q1HPV5   A0A212EKR3   A0A194QZX4   I4DIS2   A0A1E1WVB8   + More
A0A194PHH6   A0A2H1V681   A0A2A4JXF1   U4UUZ4   D6WAC0   E0VLI9   A0A0T6AX20   A0A0K8TLG6   A0A0P4VTX0   R4FN73   A0A1L8E5D4   A0A023F9Q8   A0A0V0GBP3   A0A146M2X6   A0A2S2QVJ5   A0A0A9WU71   A0A146KWD1   A0A2P8YIN1   A0A0K8TDN8   A0A1Y1LJ60   A0A310SGA0   A0A0C9RUN3   A0A3L8DEN0   A0A224XLQ5   A0A069DQ56   A0A2A3EPL8   A0A1B6C4D7   A0A182V3S7   A0A182J308   A0A182RL60   A0A182M3C3   A0A158P168   A0A182NAF2   A0A182W488   A0A182PTE6   A0A182FMN3   A0A182I9H7   B0WN00   A0A182XEM4   C4WS33   Q7QEA4   T1DMW5   Q16Z48   A0A1Q3FVV4   K7IXB0   A0A151WW43   A0A182QUX7   A0A1B6KHA6   A0A336M787   A0A336L172   A0A161MQM7   A0A232F9Q3   A0A1B6LYX6   A0A1W4XHX6   A0A182H1U0   A0A0L7QYT5   A2I3Z4   N6UEE5   D2A180   A0A1Q3FLN3   A0A1J1J6U8   A0A195CXV5   A0A0P4VTZ7   R4G571   A0A182PBS6   E2BE60   A0A182XNC2   A0A182MAK6   A0A182HQ43   E0VVT9   A0A226E072   A0A1D2NEF4   A0A182IRI7   A0A182QPI1   A0A182U829   A0A182KSL8   Q7PV70   A0A084WHT8   B0WNJ5   A0A182Y1R8   A0A151JXA4   A0A182JST8   A6YPG4   A0A170ZG36   A0A310ST38   A0A182W947   A0A182T139   A0A0L0C0X0   A0A182R5D1   A0A182VAB4   A0A164ZE12   K7J2Y6   A0A1B6CUU6   A0A0P5DNT9  

PDB

1WYN     E-value=1.13193e-19,     Score=233

KEGG

732975    K20526 transgelin | (RefSeq) muscular protein 20

GO

GO:0005516   GO:0031032   GO:0003779   GO:0005524   GO:0004672   GO:0005515   GO:0003676   GO:0008270   GO:0030060   GO:0019752   GO:0016491   GO:0016295   GO:0016296  

Length:

184

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.003

Exp number, first 60 AAs:

0

Total prob of N-in:

0.04213

outside

1  -  184

 

 

Pi

130.786201

Theta

119.906725

Tajima's D

-0.162035

CLR

23.452046

CSRT

0.328133593320334

Interpretation

Uncertain