Gene

KWMTBOMO07102  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010537

Annotation

PREDICTED:_lactase-phlorizin_hydrolase-like_[Bombyx_mori]

Location

Bomo_Chr12(+):4595372-4598762      View in EpiBrowser

Location in the cell

PlasmaMembrane   Reliability : 1.219

CDS

ATGCTGCGTTTACCATTCGCTAATTTGTTATCTTTACTGTTATCCTTTGGCATTCTAACGAGTGCAATTGGAGTGTGTGTTTGCCATAATCCACGCAGATTTCCTGAAGGGTTTATGTTCAGTACTGCAACTGCGTCATACCAAATAGAAGGCGCTTGGAATGTTGATGGAAAGACTGAAAACATTTGGGATCATATTTGCCACAAAGAACCCAGTCCCATGGCTGACAACTCTACAGGAGACATCGCAAATGATTCATATAACCTTTACAAACGAGATGTTGAAATGATAAGAGAACTTGGTATTGATTATTACAGATTCTCTGTGTCCTGGACTCGTATTTTACCCACGAGTTTCCCAGATTACATAAATGAAGCTGGAGTTGCTTATTACAATAATCTGATTGACGAATTACTCAAACACAATATTAAGCCGATGCTCACAATTTACCACTGGGACTTACCACAGAAATTGCAAGATATGGGAGGTTGGACGAACCCATATATTATCGATTGGTATGCGGACTACGCTAGAGTTCTGTTCCAAAAATTTGGTGATCGAGTTAAGAATTGGATTACTATAAACGAACCGAAAGAAATTTGTTTCCAAGGTTATGGTAATGGTACAATGGCTCCAGCATACACTATGACCGGAGTAGCCGATTACTTGTGTGGGAAGAACGTTCTTTTAGCTCACGCTAAAGCTTATCATATCTATGACAAAGAATTCCGACCTACCCAAAATGGAAATATCTCTATAACCATTAGTTGCCAATGGTATGAGCCTGAAAGCGACCGCGAGGAAGATATCACCGCCGCGAATGAAATGATCTTATTCGAGTGGGGTCAATACGGTCACCCTATATTCACTGACAGCGGTGACTATCCCGAAATAGTCAAACAACGTGTAGCAGCTAAGAGTGCTGAACAAGGTTTCTTACGTTCACGGTTCCCAGAGCTAAGTCCTGAAGAAGTTCAATACATCCGTGGAACATCAGACTTTTTTGGAGTAAATCATTATTCGACTTATTTGGCGTATAGAAACGAATCAGTAGTGGGCCACTACGCAGTACCTTCCTATTTTGATGATGCTGGAGTAATCTATTATGCTAAGGATGAATGGGCCATTGGTACGCATAACAGAATTAAGACCACACCATGGGGCTTCTACAAACTTTTGAGACAAATTTCGAATTTTTACAATAACGTACCGATTATCATCACTGAAAACGGCTTCGCGACCCTGCCCGGCTTAGAAGACAACGACCGAATCACGCATCTTAGGTTGTACTTGAACGCTGTTCTTGATGCTATTGAAGATGGATCCGATATCAGACTCTACACTTCTTGGAGTTTGATGGATAATTTTGAATGGATGAATGGTTACACGCAAAGATTCGGATTTTATGAAGTTGATTACGACAGTCCAGAACGCACACGGACACCGAGAAAATCCGCCTTTGTATTCAAAGAAATTGTAAGATCAAGGACCCTGGATTTTGATTACGAACCTGAGAGCTATGTTATGACGATCGACGCAGGAAAATGA

Protein

MLRLPFANLLSLLLSFGILTSAIGVCVCHNPRRFPEGFMFSTATASYQIEGAWNVDGKTENIWDHICHKEPSPMADNSTGDIANDSYNLYKRDVEMIRELGIDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKHNIKPMLTIYHWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYGNGTMAPAYTMTGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITISCQWYEPESDREEDITAANEMILFEWGQYGHPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGVNHYSTYLAYRNESVVGHYAVPSYFDDAGVIYYAKDEWAIGTHNRIKTTPWGFYKLLRQISNFYNNVPIIITENGFATLPGLEDNDRITHLRLYLNAVLDAIEDGSDIRLYTSWSLMDNFEWMNGYTQRFGFYEVDYDSPERTRTPRKSAFVFKEIVRSRTLDFDYEPESYVMTIDAGK

Similarity

Belongs to the glycosyl hydrolase 1 family.

Uniprot

H9JLY5   H9JLY4   A0A2A4JPS5   A0A194R3H3   A0A2H1VF65   A0A194PPG9   + More
A0A194R3H6   A0A194R360   A0A194PPG4   A0A194PMT2   A0A194R4S7   A0A194PNR8   A0A194R365   A0A194PMT8   A0A194R8P7   G9F9G9   A0A194PNS3   A0A194PU18   A0A3S2PE71   G9F9I3   A0A194R400   A0A0L7LEZ3   A0A194R3Z4   A0A212EXF5   A0A0L7KVS3   A0A194PMG8   A0A212FF90   A0A212FBG8   A0A212FF93   A0A212EXF2   H9JXB3   A0A3S2NZ22   G9F9H3   A0A2W1BA28   A0A2A4JS29   A0A2W1BGQ3   A0A2A4JCQ8   A0A2H1VVL0   A0A2A4JQ50   A0A2A4JNT8   H9JMQ9   A0A2A4JNV2   A0A2W1BPZ1   A0A212FEI2   A0A2A4JPU6   A0A194RQF8   A0A2H1VWZ6   A0A2H1WY61   O61594   A0A194PJU3   A0A2H1VWN4   A0A194PRE4   H9J7W0   A0A2W1BQ65   A0A182LWK9   H9IZH5   A0A2A4JPN8   A0A1Y9IW90   A0A182J2M6   A0NES8   A0A1Y9GKS9   A0A2H1VWC6   A0A1Y9IRG1   A0A1Y9J0G9   A0A2W1BVA2   A0A182LL18   A0A182LL19   Q7PI98   A0A2H1W4S5   A0A1Y9IS75   A0A212F3B1   W5JPP3   A0A182QNT7   A0A1Y9J0J6   A0A182TWE4   A0A2M4CLR8   A0A2M4CZ21   A0A1Y9GL87   A0A212F963   A0A194PVV9   A0A2H1W426   A0A194QDR0   A0A2H1VWQ1   A0A212F3C5   A0A2A4JTU1   A0A194QNZ7   A0A2W1BWF3   A0A182YP82   Q5TQY8   A0A1Y9IVZ0   A0A194R738   V5GZG1   A0A1Y9GKT0   A0A1Y9IRY8   A0A182U0B4   A0A182G2R0   A0A182YP83   A0A0N1IQ38   A0A182JLR1   A0A1L8DQN1  

Pubmed

19121390    26354079    26227816    22118469    28756777    11342030    + More
15511222    27936116    12364791    14747013    17210077    20966253    20920257    23761445    25244985    26483478   

EMBL

BABH01005438    BABH01005437    NWSH01000819    PCG74065.1    KQ460779    KPJ12242.1    + More
ODYU01001971    SOQ38904.1    KQ459598    KPI94629.1    KPJ12247.1    KPJ12243.1    KPI94624.1    KPI94627.1    KPJ12245.1    KPI94628.1    KPJ12248.1    KPI94632.1    KPJ12246.1    JN033714    AEW46867.1    KPI94633.1    KPI94630.1    RSAL01000077    RVE48784.1    JN033728    AEW46881.1    KPJ12249.1    JTDY01001400    KOB73970.1    KPJ12244.1    AGBW02011758    OWR46180.1    JTDY01005139    KOB67338.1    KPI94631.1    AGBW02008847    OWR52398.1    AGBW02009344    OWR51063.1    OWR52397.1    OWR46178.1    BABH01035726    RSAL01000019    RVE52748.1    JN033718    AEW46871.1    KZ150738    PZC70347.1    NWSH01000679    PCG74847.1    KZ150146    PZC72895.1    NWSH01001860    PCG69887.1    ODYU01004710    SOQ44881.1    NWSH01000883    PCG73724.1    PCG73725.1    BABH01016738    PCG73727.1    KZ149936    PZC77129.1    AGBW02008931    OWR52151.1    PCG73728.1    KQ459875    KPJ19634.1    ODYU01004903    SOQ45256.1    ODYU01011923    SOQ57942.1    AF052729    AAC06038.1    KQ459601    KPI93701.1    SOQ45257.1    KPI93700.1    BABH01020023    BABH01020024    PZC77128.1    AXCM01009805    BABH01014157    PCG73726.1    AAAB01008960    EAU76599.1    APCN01002262    ODYU01004836    SOQ45125.1    PZC77127.1    EAA44227.3    ODYU01006202    SOQ47842.1    AGBW02010585    OWR48225.1    ADMH02000892    ETN64734.1    AXCN02000455    GGFL01002037    MBW66215.1    GGFL01006404    MBW70582.1    AGBW02009638    OWR50268.1    KQ459589    KPI97521.1    ODYU01006201    SOQ47841.1    KQ459144    KPJ03597.1    SOQ45255.1    OWR48224.1    NWSH01000598    PCG75431.1    KQ458761    KPJ05206.1    PZC77130.1    EAL40075.2    KQ460870    KPJ11681.1    GALX01002583    JAB65883.1    JXUM01040976    KQ561266    KXJ79155.1    KQ459993    KPJ18573.1    GFDF01005306    JAV08778.1   

Proteomes

UP000005204    UP000218220    UP000053240    UP000053268    UP000283053    UP000037510    + More
UP000007151    UP000075883    UP000075920    UP000075880    UP000007062    UP000075840    UP000075903    UP000076407    UP000075882    UP000000673    UP000075886    UP000075902    UP000076408    UP000069940    UP000249989   

PRIDE

H9JLY5    H9JLY4    H9JXB3    H9JMQ9    H9J7W0    H9IZH5    + More

Pfam

PF00232   Glyco_hydro_1        + More
PF07782   DC_STAMP

Interpro

IPR001360   Glyco_hydro_1        + More
IPR017853   Glycoside_hydrolase_SF       
IPR033132   Glyco_hydro_1_N_CS       
IPR018120   Glyco_hydro_1_AS       
IPR012858   DC_STAMP-like       

SUPFAM

SSF51445   SSF51445       

ProteinModelPortal

H9JLY5   H9JLY4   A0A2A4JPS5   A0A194R3H3   A0A2H1VF65   A0A194PPG9   + More
A0A194R3H6   A0A194R360   A0A194PPG4   A0A194PMT2   A0A194R4S7   A0A194PNR8   A0A194R365   A0A194PMT8   A0A194R8P7   G9F9G9   A0A194PNS3   A0A194PU18   A0A3S2PE71   G9F9I3   A0A194R400   A0A0L7LEZ3   A0A194R3Z4   A0A212EXF5   A0A0L7KVS3   A0A194PMG8   A0A212FF90   A0A212FBG8   A0A212FF93   A0A212EXF2   H9JXB3   A0A3S2NZ22   G9F9H3   A0A2W1BA28   A0A2A4JS29   A0A2W1BGQ3   A0A2A4JCQ8   A0A2H1VVL0   A0A2A4JQ50   A0A2A4JNT8   H9JMQ9   A0A2A4JNV2   A0A2W1BPZ1   A0A212FEI2   A0A2A4JPU6   A0A194RQF8   A0A2H1VWZ6   A0A2H1WY61   O61594   A0A194PJU3   A0A2H1VWN4   A0A194PRE4   H9J7W0   A0A2W1BQ65   A0A182LWK9   H9IZH5   A0A2A4JPN8   A0A1Y9IW90   A0A182J2M6   A0NES8   A0A1Y9GKS9   A0A2H1VWC6   A0A1Y9IRG1   A0A1Y9J0G9   A0A2W1BVA2   A0A182LL18   A0A182LL19   Q7PI98   A0A2H1W4S5   A0A1Y9IS75   A0A212F3B1   W5JPP3   A0A182QNT7   A0A1Y9J0J6   A0A182TWE4   A0A2M4CLR8   A0A2M4CZ21   A0A1Y9GL87   A0A212F963   A0A194PVV9   A0A2H1W426   A0A194QDR0   A0A2H1VWQ1   A0A212F3C5   A0A2A4JTU1   A0A194QNZ7   A0A2W1BWF3   A0A182YP82   Q5TQY8   A0A1Y9IVZ0   A0A194R738   V5GZG1   A0A1Y9GKT0   A0A1Y9IRY8   A0A182U0B4   A0A182G2R0   A0A182YP83   A0A0N1IQ38   A0A182JLR1   A0A1L8DQN1  

PDB

5CG0     E-value=5.06517e-156,     Score=1415

KEGG

101742223    K01229 lactase-phlorizin hydrolase [EC:3.2.1.108 3.2.1.62] | (RefSeq) lactase-phlorizin hydrolase-li

PATHWAY

00052    Galactose metabolism - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0005975   GO:0004553   GO:0008152   GO:0016798   GO:0016021   GO:0008422   GO:0007608   GO:0016020   GO:0008270   GO:0005515   GO:0004319   GO:0004320   GO:0016295   GO:0016296  

PANTHER

PTHR10353  

SignalP

Position:   1 - 22,         Likelihood:  0.947560

 

 

Length:

515

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

17.43444

Exp number, first 60 AAs:

17.41483

Total prob of N-in:

0.77195

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  515

 

 

Pi

159.986378

Theta

157.932574

Tajima's D

-1.069236

CLR

0

CSRT

0.126843657817109

Interpretation

Uncertain