Gene

KWMTBOMO07090

Pre Gene Modal

BGIBMGA010429

Annotation

cytochrome_CYP338A2_[Spodoptera_littoralis]

Location

Bomo_Chr12(-):3821979-3827267      View in EpiBrowser

Full name

Cytochrome P450 6B2      

Alternative Name

CYPVIB2

Location in the cell

Nuclear   Reliability : 1.26 PlasmaMembrane   Reliability : 1.023

CDS

ATGTTCTTCGAAAGTTTCCTATTGAACTTGTCCGTACTCATCGTGTTGATAGTCGCCTTGGTATTCGATTACGTCACCAAGTTCTTCAGCTACTGGTACGTTAGGCACGTGCCCTACAAGACGCCGATCCCGTTTTTCGGCAGTGACTACCACAGGGTGCTGGGATTGACCAACAGCACTGATGAAGTTGTCAAACTGTACAACGAACATCCCGGAGACAAATTCGTCGGTCGCCTTAAAAACAGGATCCCGGATCTGATCGTAAAAGATCCGGACGCGATAAAGAGGATGTTGTCGACGGATTTCGCGTATTTCCACAGCCGAGGTCTCGGTTTAGACAAATCTCGGGACGTTTGTATACGAAACAATTTGTTTTACGCTGACGCCGAGAAATGGACTCTGCTGCGACAGGGATTGGAGGCAGTTTTGAATGGCTTGTGTCGCGAATTCGACATACATGCATGTTTGTCTGAAGCAAACGGCGACACAAACGTTCAACAGTTATTATCTGTTGTACTGGATAGTGTTTTCGACAATTTACTTCTCGGCGACGAAGGAACATCGATAAAAGAACTGAGGACTACTCTACAGAAGCGGTCGATGATCGTGAAGCTTAAAAGCTATTTGAAGAATATTTTTCCGTCAATATACGTGACGTTCGGATTATCGACGCTTCCGAATAACGTGTTGAAAAATACACGTAAATATATGGAGAGTTCGAAGCTGCAGAGGCTGATTGATGATTCTGGTTATATGCATCAAGTCAGTTTGAAAGATAAACACGTGTACGCTTTTGAGAACGAATTTGCGAGTTCGACCTTAGCATTGTTTGTCACAGAAGGCTACATACCTTGTTTGTATACATTGACCGCTTTATTTTACGAATTAGCCGTAAATCCTCAAATACAAGAAAAGGCCAGAAACTCTATCGAAAAGGATAAAGGGGTAAACTATTTGGATGCGATCATCAAAGAGACTATGAGACTACATCCGTCTCATTCGATCATTTCAAGGCAATGCGTCAAGATGTATCAATATCCTGACAGTAACTTAACTATTGATAGAAACGTCACAATTAATGTGCCAGTGGAGGCGATACACAAAGATAAGGAGCATTATGAAAACCCTGAAGTCTTCAATCCGGAGAGGTTTTTCGATGACCATGGCCCTACAAAACATAGCTACAGCTATTTACCATTCGGCGCTGGTCCGAGAAAATGCATCGGCGAACAATTGTCGTTGCGAATTATTAAAGGCGTTACTAAAATGATTCTGAACAAATACGAATTACAAACTTGCAGTAAAACACCATCTAAGTTAGCCGTAGTGGATCATGATTTCGGGAGGGTTATCGATAAAGAATTATGGCTGAATTTTAAGCTCAGAGAATTTTAA

Protein

MFFESFLLNLSVLIVLIVALVFDYVTKFFSYWYVRHVPYKTPIPFFGSDYHRVLGLTNSTDEVVKLYNEHPGDKFVGRLKNRIPDLIVKDPDAIKRMLSTDFAYFHSRGLGLDKSRDVCIRNNLFYADAEKWTLLRQGLEAVLNGLCREFDIHACLSEANGDTNVQQLLSVVLDSVFDNLLLGDEGTSIKELRTTLQKRSMIVKLKSYLKNIFPSIYVTFGLSTLPNNVLKNTRKYMESSKLQRLIDDSGYMHQVSLKDKHVYAFENEFASSTLALFVTEGYIPCLYTLTALFYELAVNPQIQEKARNSIEKDKGVNYLDAIIKETMRLHPSHSIISRQCVKMYQYPDSNLTIDRNVTINVPVEAIHKDKEHYENPEVFNPERFFDDHGPTKHSYSYLPFGAGPRKCIGEQLSLRIIKGVTKMILNKYELQTCSKTPSKLAVVDHDFGRVIDKELWLNFKLREF

Catalytic Activity

an alkane + O2 + reduced [NADPH--hemoprotein reductase] = a primary alcohol + H(+) + H2O + oxidized [NADPH--hemoprotein reductase]

Cofactor

heme

Similarity

Belongs to the cytochrome P450 family.

Keywords

Endoplasmic reticulum   Heme   Iron   Membrane   Metal-binding   Microsome   Monooxygenase   Oxidoreductase   Polymorphism  

Feature

chain  Cytochrome P450 6B2

Uniprot

H9JLM8   J7FJY0   A0A248QEH1   A0A2A4JSS5   A0A0C5CGW6   A0A0L7LMX5   + More
A0A194PJK3   A0A194QN41   A0A2H1VX51   A0A212F7D4   A0A1E1W4C3   X5D9D5   A0A2H1VVB8   A0A2J7PHB8   A0A195FT90   A0A2J7PHA8   A0A151J4A1   A0A088AEJ9   A0A151HYI5   A0A158NSG7   A0A1B6JFR3   F4WFM6   A0A2J7PHC0   A0A2J7R4Q0   A0A2J7R4P8   A0A151WI95   A0A151IFP8   A0A2J7PH77   A0A2J7R4P3   A0A3G2M0C9   A0A195FT67   A0A151WKU1   A0A026W444   B8YDH7   A0A2H1VX07   A0A0N0BI32   A0A067RK29   A0A310SDQ4   A0A2A3E7A9   D2KQK6   A0A1L8E424   A0A0L7RJX3   A0A1L1VD15   A0A195CTS0   A0A0K1YWE3   B3FQ59   A0A2J7QKF6   A0A088AEK5   A0A088AEK6   D2KQK5   A3RK61   A0A2J7QNM4   A0A310SB73   A0A3L8E4G4   F4WQ67   A0A1B6EZI3   D8V034   A0A2J7Q3M6   C7EZE3   A0A087ZNI4   D2A5J0   K7J7V5   A0A2L1K3L2   T1HT27   A0A1L8E442   A0A1L8E3Y5   A0A2J7QXU7   C9E6M9   D7EJA5   D0VFI8   A0A0U4GH49   T1HV43   A0A165RB35   A0A1L8E4E4   A0A1L8E457   A0A2A4IYM7   E0VV72   A0A2H1VHP3   A0A1L8E4N4   A0A088AEK0   A0A2S2PR94   A0A151WIA8   A0A069DV74   D2A4R6   A0A2J7QKJ3   B0XE08   A0A2A3E5S7   A0A1L8E486   J9JLB8   O76107   U5EY79   A0A1Q3FSI5   Q27664   A0A1B6K1Z8   D7EHX5   A0A1Y1L6F6   A0A2H8TW02   A0A1Y1LAU4   A0A2A4J099  

EC Number

1.14.14.1

Pubmed

19121390    22984814    28881445    26227816    26354079    22118469    + More
24361403    21347285    21719571    24508170    30249741    24845553    25547988    18510975    20301224    18362917    19820115    20075255    22391394    20566863    26334808    9535163    8541882    28004739   

EMBL

BABH01005372    BABH01005373    AK343222    BAM73904.1    JX310075    AFP20586.1    + More
KX443449    ASO98024.1    NWSH01000640    PCG75095.1    KP001137    AJN91182.1    JTDY01000528    KOB76797.1    KQ459603    KPI92904.1    KQ461194    KPJ06927.1    ODYU01004660    SOQ44784.1    AGBW02009887    OWR49642.1    GDQN01009229    JAT81825.1    KF701157    AHW57327.1    SOQ44785.1    NEVH01025142    PNF15724.1    KQ981276    KYN43522.1    PNF15721.1    KQ980159    KYN17418.1    KQ976719    KYM76763.1    ADTU01024898    ADTU01024899    GECU01009671    JAS98035.1    GL888120    EGI67003.1    PNF15722.1    NEVH01007403    PNF35811.1    PNF35807.1    KQ983089    KYQ47558.1    KQ977780    KYM99949.1    PNF15695.1    PNF35808.1    MG840830    AYN79706.1    KYN43497.1    KQ983001    KYQ48478.1    KK107447    QOIP01000001    EZA50778.1    RLU27579.1    FJ524855    KX443427    ACL77781.1    ASO98002.1    ODYU01004908    SOQ45266.1    KQ435735    KOX77154.1    KK852632    KDR19800.1    KQ762659    OAD55551.1    KZ288358    PBC27059.1    GU263828    ADA68174.1    GFDF01000584    JAV13500.1    KQ414574    KOC71252.1    JN984869    AFU75895.1    KQ977329    KYN03529.1    KP859379    AKZ17689.1    EU344879    ACA51846.1    NEVH01013262    PNF29066.1    GU263827    ADA68173.1    EF421246    ABN80241.2    NEVH01012673    PNF30179.1    KQ761855    OAD56568.1    RLU27574.1    GL888262    EGI63690.1    GECZ01026392    GECZ01007074    JAS43377.1    JAS62695.1    GQ292715    ACT68012.1    NEVH01019066    PNF23159.1    GQ330542    ACT78507.2    KQ971345    EFA05730.1    AAZX01003229    MG595274    AVE15906.1    ACPB03016173    GFDF01000593    JAV13491.1    GFDF01000641    JAV13443.1    NEVH01009372    PNF33413.1    GQ465039    JN862817    ACV88721.2    AEV46849.1    DS497699    EFA12634.1    GU074517    ACY41036.1    KT071009    ALX81394.1    ACPB03026915    KR028423    KX945359    MF471392    LC223827    AML23849.1    ATB55047.1    ATN95998.1    BAZ96564.1    GFDF01000669    JAV13415.1    GFDF01000670    JAV13414.1    NWSH01004601    PCG64861.1    DS235804    EEB17278.1    ODYU01002604    SOQ40326.1    GFDF01000592    JAV13492.1    GGMR01019372    MBY31991.1    KYQ47582.1    GBGD01001173    JAC87716.1    KQ971344    EFA05713.1    PNF29106.1    DS232795    EDS45780.1    PBC27055.1    GFDF01000608    JAV13476.1    ABLF02026945    AB001323    BAA28946.1    GANO01000462    JAB59409.1    GFDL01004476    JAV30569.1    U18085    GECU01002246    JAT05461.1    KQ971323    KYB28569.1    GEZM01063158    JAV69263.1    GFXV01006285    MBW18090.1    GEZM01064604    JAV68696.1    PCG64860.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053268    UP000053240    UP000007151    + More
UP000235965    UP000078541    UP000078492    UP000005203    UP000078540    UP000005205    UP000007755    UP000075809    UP000078542    UP000053097    UP000279307    UP000053105    UP000027135    UP000242457    UP000053825    UP000007266    UP000002358    UP000015103    UP000009046    UP000002320    UP000007819   

PRIDE

H9JLM8   

Pfam

PF00067   p450

Interpro

IPR002403   Cyt_P450_E_grp-IV        + More
IPR036396   Cyt_P450_sf       
IPR017972   Cyt_P450_CS       
IPR001128   Cyt_P450       
IPR002401   Cyt_P450_E_grp-I       
IPR002402   Cyt_P450_E_grp-II       

SUPFAM

SSF48264   SSF48264       

Gene 3D

1.10.630.10    

ProteinModelPortal

H9JLM8   J7FJY0   A0A248QEH1   A0A2A4JSS5   A0A0C5CGW6   A0A0L7LMX5   + More
A0A194PJK3   A0A194QN41   A0A2H1VX51   A0A212F7D4   A0A1E1W4C3   X5D9D5   A0A2H1VVB8   A0A2J7PHB8   A0A195FT90   A0A2J7PHA8   A0A151J4A1   A0A088AEJ9   A0A151HYI5   A0A158NSG7   A0A1B6JFR3   F4WFM6   A0A2J7PHC0   A0A2J7R4Q0   A0A2J7R4P8   A0A151WI95   A0A151IFP8   A0A2J7PH77   A0A2J7R4P3   A0A3G2M0C9   A0A195FT67   A0A151WKU1   A0A026W444   B8YDH7   A0A2H1VX07   A0A0N0BI32   A0A067RK29   A0A310SDQ4   A0A2A3E7A9   D2KQK6   A0A1L8E424   A0A0L7RJX3   A0A1L1VD15   A0A195CTS0   A0A0K1YWE3   B3FQ59   A0A2J7QKF6   A0A088AEK5   A0A088AEK6   D2KQK5   A3RK61   A0A2J7QNM4   A0A310SB73   A0A3L8E4G4   F4WQ67   A0A1B6EZI3   D8V034   A0A2J7Q3M6   C7EZE3   A0A087ZNI4   D2A5J0   K7J7V5   A0A2L1K3L2   T1HT27   A0A1L8E442   A0A1L8E3Y5   A0A2J7QXU7   C9E6M9   D7EJA5   D0VFI8   A0A0U4GH49   T1HV43   A0A165RB35   A0A1L8E4E4   A0A1L8E457   A0A2A4IYM7   E0VV72   A0A2H1VHP3   A0A1L8E4N4   A0A088AEK0   A0A2S2PR94   A0A151WIA8   A0A069DV74   D2A4R6   A0A2J7QKJ3   B0XE08   A0A2A3E5S7   A0A1L8E486   J9JLB8   O76107   U5EY79   A0A1Q3FSI5   Q27664   A0A1B6K1Z8   D7EHX5   A0A1Y1L6F6   A0A2H8TW02   A0A1Y1LAU4   A0A2A4J099  

PDB

6MA7     E-value=9.60056e-21,     Score=248

KEGG

101736895    K14999 cytochrome P450 family 6 [EC:1.14.-.-] | (RefSeq) CYP338A1; cytochrome P450 6B2-like

GO

GO:0016705   GO:0005506   GO:0016021   GO:0004497   GO:0020037   GO:0046872   GO:0005739   GO:0070330   GO:0005789   GO:0008270   GO:0005515   GO:0004319   GO:0004320   GO:0016295   GO:0016296   GO:0055114  

Subcellular location

Endoplasmic reticulum membrane  
Microsome membrane  

Length:

464

Number of predicted TMHs:

1

Exp number of AAs in TMHs:

31.0719

Exp number, first 60 AAs:

20.91196

Total prob of N-in:

0.72003

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  26

outside

27  -  464

 

 

Pi

147.191654

Theta

54.865335

Tajima's D

2.17131

CLR

0.160411

CSRT

0.907154642267887

Interpretation

Uncertain