Gene

KWMTBOMO07081

Annotation

Cornichon_[Operophtera_brumata]

Location

Bomo_Chr12(-):3231420-3235807      View in EpiBrowser

Full name

Protein cornichon      

Location in the cell

PlasmaMembrane   Reliability : 4.873

CDS

ATGGCGTTTAGTTTTCCAGCCTTTGCGTATATTGTTGCCTTAATAACCGATGCATTTTTAATATTTTTCTCTATATTTCACGTTATAGCCTTCGACGAACTAAAAACTGACTACAAAAATCCCATCGATCAATGCAATAGTTTGAATCCTTTGGTTTTGCCGGAATATTTACTGCATTTGCTCATTAATGTACTGTTCTTGCTGTCCGGAGAATGGTTTTCGTTATTGATCAACATTCCTTTAATACTATACCACATACACAGATACTACACAAGGCCAGTCATGTCAGGTCCAGGTCTGTATGACCCGACAAGTATTATGAATGCAGATGTATTAACTTCATGTCAGAGGGAAGGCTGGATAAAGCTGGCATTTTACTTGCTGTCGTTCTTCCTATATCTTTATGGAATGATCGTGGTGTTGATTGCGGCGTAA

Protein

MAFSFPAFAYIVALITDAFLIFFSIFHVIAFDELKTDYKNPIDQCNSLNPLVLPEYLLHLLINVLFLLSGEWFSLLINIPLILYHIHRYYTRPVMSGPGLYDPTSIMNADVLTSCQREGWIKLAFYLLSFFLYLYGMIVVLIAA

Description

Acts as cargo receptor necessary for the transportation of gurken (grk) to a transitional endoplasmic reticulum (tER) site and promotes its incorporation into coat protein complex II (COPII) vesicles. Associated with gurken, produces a signal received by torpedo resulting in a signaling pathway that first establishes posterior follicle cell fates and normal localization of the anterior and posterior determinants, later they act in a signaling event inducing dorsal follicle cell fates and regulating the dorsal-ventral pattern of egg and embryo.
Acts as cargo receptor necessary for the transportation of gurken (grk) to a transitional endoplasmic reticulum (tER) site and promotes its incorporation into coat protein complex II (COPII) vesicles. Associated with gurken, produces a signal received by torpedo resulting in a signaling pathway that first establishes posterior follicle cell fates and normal localization of the anterior and posterior determinants, later they act in a signaling event inducing dorsal follicle cell fates and regulating the dorsal-ventral pattern of egg and embryo (By similarity).

Subunit

Interacts with grk.

Similarity

Belongs to the cornichon family.

Keywords

Complete proteome   Developmental protein   Endoplasmic reticulum   ER-Golgi transport   Membrane   Protein transport   Receptor   Reference proteome   Transmembrane   Transmembrane helix   Transport  

Feature

chain  Protein cornichon

Uniprot

A0A0L7LM61   A0A3S2TPT5   A0A2H1UZK1   A0A212FA84   S4PS54   D6WLE9   + More
I4DP33   A0A182JBA0   A0A1L8DV30   U5EM43   A0A1B0GPQ2   A0A2P8ZLZ4   A0A139WH69   A0A2J7R8M6   A0A067RD48   A0A2M3ZE16   A0A2M4AVF8   W5JVX0   A0A182F316   R4WDC1   A0A194PJL3   Q172M8   A0A023EE82   A0A1Q3FBV4   B0WRE4   A0A182NUP5   A0A0T6B2P7   A0A182RZB4   A0A182WGB7   A0A1B6L7H4   A0A023F9P2   R4G4D4   A0A182UXN3   A0A182WXL8   Q7PWG7   A0A182I7I2   A0A182QLC5   A0A224XVW3   A0A084WQK5   A0A182HCJ5   E9HJT3   A0A1W4WSK6   A0A2R7W0T9   A0A0P5VVU2   A0A164YC13   A0A2P2HYL8   A0A182Y0H4   A0A182KF06   A0A182T2V6   A0A182PVU2   A0A182LMJ8   K7J0R5   A0A226EKL1   A0A0A9YLW8   A0A336MAR6   A0A0P5IDQ6   J3JU84   A0A0P6G364   A0A1D2MI40   E0VNZ1   A0A0N7ZD36   A0A3B0KCW3   Q29NM5   B4GQN2   A0A0L0BZF8   A0A1I8MH61   A0A1I8Q4B7   A0A0C9RR36   B4Q701   A0A1W4VWF9   B3MJN8   A0A0P5YS29   B4I217   M9PDJ6   P49858   A0A1L8EHC4   A0A0M5J413   B4MU61   B4NXP4   B3N6D0   D3TRN8   A0A0K8U5G9   A0A087UX33   A0A034W1T8   A0A2S2N644   A0A0L7RDL0   A0A0Q9WAH1   B4KI22   P52159   C1BZZ6   A0A1A9WM33   J9JJ49   A0A0Q9X5X3   A0A0P6ENN8   T1K2W9   A0A2H8TJM0   C1BUM3   A0A0N8DPJ5   K1QF47   R7TQB5  

Pubmed

26227816    22118469    23622113    18362917    19820115    22651552    + More
29403074    24845553    20920257    23761445    23691247    26354079    17510324    26999592    24945155    25474469    12364791    14747013    17210077    24438588    26483478    21292972    25244985    20966253    20075255    25401762    26823975    22516182    23537049    27289101    20566863    15632085    17994087    26108605    25315136    22936249    18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    26109357    26109356    7540118    10471707    16396907    17550304    20353571    25348373    22992520    23254933   

EMBL

JTDY01000662    KOB76296.1    RSAL01000028    RVE51855.1    ODYU01000002    SOQ34048.1    + More
AGBW02009509    OWR50647.1    GAIX01014153    JAA78407.1    KQ971343    EFA04607.2    AK403273    BAM19673.1    AXCP01008274    GFDF01003939    JAV10145.1    GANO01001156    JAB58715.1    AJVK01059953    PYGN01000019    PSN57522.1    KYB27195.1    NEVH01006721    PNF37187.1    KK852543    KDR21662.1    GGFM01005994    MBW26745.1    GGFK01011277    MBW44598.1    ADMH02000253    ETN67235.1    AK417543    BAN20758.1    KQ459603    KPI92914.1    CH477434    GDUN01000301    EAT40979.1    JAN95618.1    GAPW01005676    GAPW01005675    JAC07923.1    GFDL01009980    JAV25065.1    DS232054    EDS33334.1    LJIG01016078    KRT81680.1    GEBQ01020357    JAT19620.1    GBBI01000515    JAC18197.1    GAHY01000866    JAA76644.1    AAAB01008984    EAA14788.4    APCN01003407    AXCN02000736    GFTR01002428    JAW13998.1    ATLV01025637    KE525396    KFB52499.1    JXUM01033516    KQ560991    KXJ80103.1    GL732664    EFX67993.1    KK854227    PTY13353.1    GDIP01094462    GDIQ01020652    JAM09253.1    JAN74085.1    LRGB01000930    KZS15100.1    IACF01001162    LAB66878.1    LNIX01000003    OXA57647.1    GBHO01033035    GBHO01022712    GBHO01022708    GBHO01022707    GBHO01022704    GBHO01022703    GBHO01019974    GBHO01019973    GBHO01019968    GBHO01011016    GBHO01011015    GBHO01011013    GBRD01001694    GBRD01001693    GDHC01013935    GDHC01009323    JAG10569.1    JAG20892.1    JAG20896.1    JAG20897.1    JAG20900.1    JAG20901.1    JAG23630.1    JAG23631.1    JAG23636.1    JAG32588.1    JAG32589.1    JAG32591.1    JAG64127.1    JAQ04694.1    JAQ09306.1    UFQS01000637    UFQT01000637    SSX05640.1    SSX25999.1    GDIQ01214870    JAK36855.1    APGK01046742    BT126797    KB741067    KB631751    AEE61759.1    ENN74410.1    ERL85793.1    GDIQ01040531    JAN54206.1    LJIJ01001181    ODM92633.1    DS235354    EEB15097.1    GDRN01053657    JAI66152.1    OUUW01000006    SPP81478.1    CH379059    EAL34193.2    CH479187    EDW39904.1    JRES01001119    KNC25393.1    GBYB01009746    JAG79513.1    CM000361    CM002910    EDX05209.1    KMY90498.1    CH902620    EDV31377.1    KPU73341.1    GDIQ01227321    GDIP01055477    JAK24404.1    JAM48238.1    CH480820    EDW54574.1    AE014134    KX531432    AGB93030.1    ANY27242.1    U28069    BT011529    GFDG01000806    JAV17993.1    CP012523    ALC39756.1    CH963852    EDW75650.1    CM000157    EDW89669.1    CH954177    EDV58099.1    EZ424090    ADD20366.1    GDHF01030694    JAI21620.1    KK122098    KFM81922.1    GAKP01010660    JAC48292.1    GGMR01000024    MBY12643.1    KQ414613    KOC68938.1    CH940649    KRF81350.1    CH933807    EDW11304.1    KRG02634.1    BT080175    ACO14599.1    ABLF02038238    KRG02633.1    GDIQ01060030    JAN34707.1    CAEY01001369    GFXV01002067    MBW13872.1    BT078302    BT121519    ACO12726.1    ADD38449.1    GDIP01013487    JAM90228.1    JH816867    EKC29744.1    AMQN01011676    KB309022    ELT95757.1   

Proteomes

UP000037510    UP000283053    UP000007151    UP000007266    UP000075880    UP000092462    + More
UP000245037    UP000235965    UP000027135    UP000000673    UP000069272    UP000053268    UP000008820    UP000002320    UP000075884    UP000075900    UP000075920    UP000075903    UP000076407    UP000007062    UP000075840    UP000075886    UP000030765    UP000069940    UP000249989    UP000000305    UP000192223    UP000076858    UP000076408    UP000075881    UP000075901    UP000075885    UP000075882    UP000002358    UP000198287    UP000019118    UP000030742    UP000094527    UP000009046    UP000268350    UP000001819    UP000008744    UP000037069    UP000095301    UP000095300    UP000000304    UP000192221    UP000007801    UP000001292    UP000000803    UP000092553    UP000007798    UP000002282    UP000008711    UP000054359    UP000053825    UP000008792    UP000009192    UP000091820    UP000007819    UP000015104    UP000005408    UP000014760   

PRIDE

M9PDJ6    P49858   

Pfam

PF03311   Cornichon        + More
PF00201   UDPGT

Interpro

IPR003377   Cornichon        + More
IPR033466   Cornichon_conserved       
IPR002213   UDP_glucos_trans       

ProteinModelPortal

A0A0L7LM61   A0A3S2TPT5   A0A2H1UZK1   A0A212FA84   S4PS54   D6WLE9   + More
I4DP33   A0A182JBA0   A0A1L8DV30   U5EM43   A0A1B0GPQ2   A0A2P8ZLZ4   A0A139WH69   A0A2J7R8M6   A0A067RD48   A0A2M3ZE16   A0A2M4AVF8   W5JVX0   A0A182F316   R4WDC1   A0A194PJL3   Q172M8   A0A023EE82   A0A1Q3FBV4   B0WRE4   A0A182NUP5   A0A0T6B2P7   A0A182RZB4   A0A182WGB7   A0A1B6L7H4   A0A023F9P2   R4G4D4   A0A182UXN3   A0A182WXL8   Q7PWG7   A0A182I7I2   A0A182QLC5   A0A224XVW3   A0A084WQK5   A0A182HCJ5   E9HJT3   A0A1W4WSK6   A0A2R7W0T9   A0A0P5VVU2   A0A164YC13   A0A2P2HYL8   A0A182Y0H4   A0A182KF06   A0A182T2V6   A0A182PVU2   A0A182LMJ8   K7J0R5   A0A226EKL1   A0A0A9YLW8   A0A336MAR6   A0A0P5IDQ6   J3JU84   A0A0P6G364   A0A1D2MI40   E0VNZ1   A0A0N7ZD36   A0A3B0KCW3   Q29NM5   B4GQN2   A0A0L0BZF8   A0A1I8MH61   A0A1I8Q4B7   A0A0C9RR36   B4Q701   A0A1W4VWF9   B3MJN8   A0A0P5YS29   B4I217   M9PDJ6   P49858   A0A1L8EHC4   A0A0M5J413   B4MU61   B4NXP4   B3N6D0   D3TRN8   A0A0K8U5G9   A0A087UX33   A0A034W1T8   A0A2S2N644   A0A0L7RDL0   A0A0Q9WAH1   B4KI22   P52159   C1BZZ6   A0A1A9WM33   J9JJ49   A0A0Q9X5X3   A0A0P6ENN8   T1K2W9   A0A2H8TJM0   C1BUM3   A0A0N8DPJ5   K1QF47   R7TQB5  

KEGG

101736486    K20368 protein cornichon | (RefSeq) protein cornichon

GO

GO:0016192   GO:0016021   GO:0016758   GO:0005789   GO:0007310   GO:0009952   GO:0006888   GO:0007350   GO:0046843   GO:0015031   GO:0006810   GO:0000287   GO:0005634   GO:0008270   GO:0005515   GO:0004319   GO:0004320   GO:0016295   GO:0016296  

Subcellular location

Endoplasmic reticulum membrane  

Length:

144

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

67.21236

Exp number, first 60 AAs:

24.14336

Total prob of N-in:

0.99561

POSSIBLE N-term signal

sequence

inside

1  -  6

TMhelix

7  -  29

outside

30  -  59

TMhelix

60  -  82

inside

83  -  122

TMhelix

123  -  142

outside

143  -  144

 

 

Pi

141.58356

Theta

145.633016

Tajima's D

-0.998225

CLR

0.438564

CSRT

0.142792860356982

Interpretation

Uncertain