Gene

KWMTBOMO07080

Pre Gene Modal

BGIBMGA010432

Annotation

UDP-glycosyltransferase_UGT46A1_[Bombyx_mori]

Location

Bomo_Chr12(-):3219730-3220687      View in EpiBrowser

Full name

UDP-glucuronosyltransferase      

Location in the cell

PlasmaMembrane   Reliability : 2.225

CDS

ATGCGTGCCGTGCCATTTCATTACATTCTGCTCGTGTTTATAAAAGATGTGTTGCCGGCTAGAATTCTCGGCCTGTTCCCTCATATCGGAAAAAGTCATCAAATGGCATACGACCCTTTGTTACGAAGATTGGCTGAGAGAGGACACGATGTCACCGCCGTAACATTCTTTCCCTTGAAAGATCCACCGGAACATTACAGAGCAGTCAGCCTGGAAGGACTCACCGAAATCAGAGTTGAAAGTATTAACATGTCAATCTATGAGGGACACAATGTTTTCCTTCGACTTACTGGATTGGACAGAATTCGATCACACATTAGTGAAATTCACCCGTTGGCAGACTTCGCTTTAGATACGTGCTCGAAGTTAGTGAGTTTTAAGCCTTTATCAGAACTACTTAGGAAAGAATACGATGTGATATTAACGGAGAATTTCAACAGCGACTGTATGCTAGGTCTCGCAAATGTTTATGGACAGAAAGCGCCTATTGTTTATCTGTCGTCGTGCACTGCAATGTACTGGGCTCTGGACCGGTTCGGAGTAACGGATAATCCGTCATACGTGCCCCTTGTCAGTTCAATATTTACCACCCCAATGACATTCCTACAGAGATTAGAGAATGCCGTGCTTAATGTATATTTCAAAGTCTGGTTCCGATACGCGATTCAGCTTAAAGAACAAAAAATAATTGAGGAACATTTCGGTAGAAAGATACCCGATCTTCAAGAGATGGCGAAGAATGTGTCTTTGATGTTAGTGAACGCGCACCACAGCTTGAACGGTGTTCGACCTTTAATCCCTGGTATCGTGGAAGTAGGCGGCATGCACTTGGATAAAACAAGGAGACCTATATCACAAGTAAGCGAATGA

Protein

MRAVPFHYILLVFIKDVLPARILGLFPHIGKSHQMAYDPLLRRLAERGHDVTAVTFFPLKDPPEHYRAVSLEGLTEIRVESINMSIYEGHNVFLRLTGLDRIRSHISEIHPLADFALDTCSKLVSFKPLSELLRKEYDVILTENFNSDCMLGLANVYGQKAPIVYLSSCTAMYWALDRFGVTDNPSYVPLVSSIFTTPMTFLQRLENAVLNVYFKVWFRYAIQLKEQKIIEEHFGRKIPDLQEMAKNVSLMLVNAHHSLNGVRPLIPGIVEVGGMHLDKTRRPISQVSE

Catalytic Activity

glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP

Similarity

Belongs to the UDP-glycosyltransferase family.

Feature

chain  UDP-glucuronosyltransferase

Uniprot

G9LPW0   H9JLN1   A0A2A4JGJ6   H9JLN2   G9LPR6   G9LPW1   + More
A0A191T2K5   A0A024AG07   A0A0L7LLJ1   A0A2H1UZP8   A0A194QN20   A0A212FA80   A0A286MXP6   A0A2A4IU38   A0A194PJL3   G9LPR7   A0A1L8D6Q2   A0A2H4WB48   A0A194PP57   A0A194QN29   A0A194PHM3   S4NV72   A0A212FA68   A0A194QTP4   A0A0L7L3K3   G9LPR8   A0A2A4JI28   A0A2H1VU07   G9LPW2   A0A2J7R4S8   A0A067RM85   A0A023ES06   A0A182LUV0   A0A067RAD1   A0A139WIV0   A0A182GI26   Q17NF9   A0A1S4EWK0   A0A2P8YRW0   A0A1W4WMC9   A0A1Q3FS33   A0A1S4F2K0   D2A2V5   A0A182L244   Q17HG0   A0A336KCF6   A0A182F4L8   A0A1W4WYE4   A0A1Q3FRR9   A0A182RBM8   A0A182YGV2   A0A182W9Q0   A0A182YGU9   A0A0J7KXW2   A0A1L8E1G2   B0WBP8   A0A1B6D7V3   A0A182WT90   A0A182HV86   A0A182SC34   A0A084VP43   A0A182WT93   A0A1W7R8J2   A0A182IX39   A0A182L242   A0A1S4GXF8   A0A2J7R4W8   A0A2J7R4W2   A0A0C9RY58   A0A182RBM5   A0A1Q3FPW9   A0A182V6Z3   A0A1B0DEG4   A0A182NXB2   A0A1Q3FPY1   A0A1B0AZ72   A0A182PJ67   A0A182VNM4   A0A182UEM4   A0A067RCS0   D2A2K6   B0WBP4   A0A2P8ZG78   A0A182PJ64   A0A182HV83   W5JBD1   A0A1S4HCP9   A0A0C9RNU1   A0A182QSB1   A0A034V8V2   A0A2P8ZGB0   A0A0A1WW96   Q7Q3K2   J9JN70   A0A1I8N2C0   A0A2M3Z1Z1   A0A182NE44   R4UWK4   A0A0L0C9T9   A0A182JNW2  

EC Number

2.4.1.17

Pubmed

22155036    19121390    24698447    26227816    26354079    22118469    + More
19954531    25299618    29027758    23622113    24845553    24945155    18362917    19820115    26483478    17510324    29403074    20966253    25244985    24438588    12364791    20920257    23761445    25348373    25830018    25315136    26108605   

EMBL

JQ070267    AEW43183.1    BABH01005332    NWSH01001533    PCG70939.1    BABH01005330    + More
JQ070223    AEW43139.1    JQ070268    AEW43184.1    KU680309    ANI22015.1    KF777119    AHY99690.1    JTDY01000662    KOB76295.1    ODYU01000002    SOQ34049.1    KQ461194    KPJ06918.1    AGBW02009509    OWR50646.1    MF684364    ASX93998.1    NWSH01008094    PCG62692.1    KQ459603    KPI92914.1    JQ070224    AEW43140.1    GEYN01000082    JAV02047.1    KY202928    AUC64272.1    KPI92915.1    KPJ06917.1    KPI92916.1    GAIX01013062    JAA79498.1    OWR50645.1    KPJ06916.1    JTDY01003254    KOB69869.1    JQ070225    AEW43141.1    NWSH01001496    PCG71080.1    ODYU01004162    SOQ43734.1    JQ070269    AEW43185.1    NEVH01007402    PNF35836.1    KK852590    KDR20747.1    GAPW01001591    JAC12007.1    AXCM01009219    KDR20744.1    KQ971338    KYB27844.1    JXUM01065169    KQ562333    KXJ76125.1    CH477199    EAT48259.1    PYGN01000401    PSN46991.1    GFDL01004783    JAV30262.1    EFA02977.2    CH477249    EAT46102.1    UFQS01000219    UFQT01000219    SSX01542.1    SSX21922.1    GFDL01004746    JAV30299.1    LBMM01002015    KMQ95392.1    GFDF01001547    JAV12537.1    DS231880    EDS42583.1    GEDC01015537    JAS21761.1    APCN01002501    ATLV01014974    KE524999    KFB39737.1    GEHC01000181    JAV47464.1    AAAB01008964    PNF35870.1    PNF35872.1    GBYB01012856    JAG82623.1    GFDL01005396    JAV29649.1    AJVK01032731    AJVK01032732    GFDL01005384    JAV29661.1    JXJN01006200    KDR20746.1    EFA02010.1    EDS42579.1    PYGN01000068    PSN55501.1    ADMH02001962    ETN60165.1    GBYB01008756    JAG78523.1    AXCN02000871    GAKP01020964    JAC37988.1    PSN55490.1    GBXI01011391    JAD02901.1    EAA12774.4    ABLF02040513    GGFM01001770    MBW22521.1    KC740857    AGM32681.1    JRES01000714    KNC29017.1   

Proteomes

UP000005204    UP000218220    UP000037510    UP000053240    UP000007151    UP000053268    + More
UP000235965    UP000027135    UP000075883    UP000007266    UP000069940    UP000249989    UP000008820    UP000245037    UP000192223    UP000075882    UP000069272    UP000075900    UP000076408    UP000075920    UP000036403    UP000002320    UP000076407    UP000075840    UP000075901    UP000030765    UP000075880    UP000075903    UP000092462    UP000075884    UP000092460    UP000075885    UP000075902    UP000000673    UP000075886    UP000007062    UP000007819    UP000095301    UP000037069    UP000075881   

PRIDE

G9LPW0    H9JLN1    H9JLN2    G9LPW1    G9LPW2   

Pfam

PF00201   UDPGT        + More
PF03311   Cornichon
PF00108   Thiolase_N
PF02803   Thiolase_C
PF02036   SCP2

Interpro

IPR002213   UDP_glucos_trans        + More
IPR035595   UDP_glycos_trans_CS       
IPR033466   Cornichon_conserved       
IPR003377   Cornichon       
IPR020613   Thiolase_CS       
IPR020617   Thiolase_C       
IPR016039   Thiolase-like       
IPR003033   SCP2_sterol-bd_dom       
IPR020615   Thiolase_acyl_enz_int_AS       
IPR020616   Thiolase_N       
IPR036527   SCP2_sterol-bd_dom_sf       

SUPFAM

SSF53901   SSF53901        + More
SSF55718   SSF55718       

Gene 3D

3.30.1050.10     3.40.47.10    

ProteinModelPortal

G9LPW0   H9JLN1   A0A2A4JGJ6   H9JLN2   G9LPR6   G9LPW1   + More
A0A191T2K5   A0A024AG07   A0A0L7LLJ1   A0A2H1UZP8   A0A194QN20   A0A212FA80   A0A286MXP6   A0A2A4IU38   A0A194PJL3   G9LPR7   A0A1L8D6Q2   A0A2H4WB48   A0A194PP57   A0A194QN29   A0A194PHM3   S4NV72   A0A212FA68   A0A194QTP4   A0A0L7L3K3   G9LPR8   A0A2A4JI28   A0A2H1VU07   G9LPW2   A0A2J7R4S8   A0A067RM85   A0A023ES06   A0A182LUV0   A0A067RAD1   A0A139WIV0   A0A182GI26   Q17NF9   A0A1S4EWK0   A0A2P8YRW0   A0A1W4WMC9   A0A1Q3FS33   A0A1S4F2K0   D2A2V5   A0A182L244   Q17HG0   A0A336KCF6   A0A182F4L8   A0A1W4WYE4   A0A1Q3FRR9   A0A182RBM8   A0A182YGV2   A0A182W9Q0   A0A182YGU9   A0A0J7KXW2   A0A1L8E1G2   B0WBP8   A0A1B6D7V3   A0A182WT90   A0A182HV86   A0A182SC34   A0A084VP43   A0A182WT93   A0A1W7R8J2   A0A182IX39   A0A182L242   A0A1S4GXF8   A0A2J7R4W8   A0A2J7R4W2   A0A0C9RY58   A0A182RBM5   A0A1Q3FPW9   A0A182V6Z3   A0A1B0DEG4   A0A182NXB2   A0A1Q3FPY1   A0A1B0AZ72   A0A182PJ67   A0A182VNM4   A0A182UEM4   A0A067RCS0   D2A2K6   B0WBP4   A0A2P8ZG78   A0A182PJ64   A0A182HV83   W5JBD1   A0A1S4HCP9   A0A0C9RNU1   A0A182QSB1   A0A034V8V2   A0A2P8ZGB0   A0A0A1WW96   Q7Q3K2   J9JN70   A0A1I8N2C0   A0A2M3Z1Z1   A0A182NE44   R4UWK4   A0A0L0C9T9   A0A182JNW2  

KEGG

100862832    K00699 glucuronosyltransferase [EC:2.4.1.17] | (RefSeq) UGT46A1; UDP-glycosyltransferase UGT46A1

PATHWAY

00040    Pentose and glucuronate interconversions - Bombyx mori (domestic silkworm)
00053    Ascorbate and aldarate metabolism - Bombyx mori (domestic silkworm)
00830    Retinol metabolism - Bombyx mori (domestic silkworm)
00860    Porphyrin and chlorophyll metabolism - Bombyx mori (domestic silkworm)
00980    Metabolism of xenobiotics by cytochrome P450 - Bombyx mori (domestic silkworm)
00982    Drug metabolism - cytochrome P450 - Bombyx mori (domestic silkworm)
00983    Drug metabolism - other enzymes - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0015020   GO:0016021   GO:0016758   GO:0016192   GO:0008194   GO:0043231   GO:0016747   GO:0008152   GO:0000287   GO:0005634   GO:0008270   GO:0005515   GO:0004319   GO:0004320   GO:0016295   GO:0016296  

Subcellular location

Membrane  

Length:

289

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

1.30837

Exp number, first 60 AAs:

1.24275

Total prob of N-in:

0.06409

outside

1  -  289

 

 

Pi

172.490308

Theta

207.377394

Tajima's D

-0.593662

CLR

34.038921

CSRT

0.220938953052347

Interpretation

Uncertain