Gene

KWMTBOMO07071  Validated by peptides from experiments

Pre Gene Modal

BGIBMGA010523

Annotation

PREDICTED:_N-acetylgalactosaminyltransferase_7_isoform_X2_[Papilio_xuthus]

Location

Bomo_Chr12(+):3120428-3127966      View in EpiBrowser

Full name

Polypeptide N-acetylgalactosaminyltransferase       + More
N-acetylgalactosaminyltransferase 7      

Alternative Name

Protein-UDP acetylgalactosaminyltransferase
Protein-UDP acetylgalactosaminyltransferase 7
UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7
dGalNAc-T2

Location in the cell

Cytoplasmic   Reliability : 2.781

CDS

ATGTCACAGAAGCATGCCAATGATGTAGCAGAGACTGAGAGTAAATACGGAATGAATATAGCTGCATCAAATGATATTGCAATGAACAGATCGATACCGGATACGCGGCTCGATGAATGCAAATACTGGCACTACCCCGAAGATCTGGCCAAGACATCTGTAATCATCGTCTTCCATAATGAGGGCTTCTCCGTTCTCATGAGAACCGTCCACAGCGTTATTAACAGAACTCCTGCGCAATTTCTGCATGAAGTCGTCTTGGTCGATGATTTCTCCGATAAAGATGACTTAAAAGAAAATTTAGATAATTACATAAAGAGGTGGAATGGTAAAGTGCGTCTTGTGCGTAATGTGCAACGCGAGGGACTGATTCGTACCAGATCGAGGGGGGCCCAAGAAGCGACCGGCGACGTCATAGTCTTCCTTGACGCTCACTGCGAAGTCAATGTCAACTGGCTCCCTCCGCTCTTAGCCCCCATATACAGGGACTACAGAACTATGACCGTGCCCGTTATAGACGGTATAGATTACAACACATTCGAATACAGACCCGTATACCAACACGGAACGAATTACCGCGGTATATTTGAATGGGGTATGTTGTACAAAGAGAACGAAGTGCCCGACAGAGAAGCACATCTTCACAAGCACAAGTCGGAGCCGTACAAGAGTCCGACACACGCTGGAGGCCTGTTCGCCATCAACAGACGATACTTCTTAGAGATAGGCGCGTACGACCCTGGTCTCTTGGTGTGGGGAGGGGAGAACTTTGAGTTGAGCTTCAAAATATGGCAATGCGGTGGCAGCATAGAATGGGTGCCGTGCTCGCGAGTAGGTCACGTATACAGAGCCTTCATGCCGTATACGTTCGGTAACTTGGCCAAAAATCGCAAAGGCTCCCTCATTACGATAAACTACAAACGCGTCATCGAGACCTGGTTCGATGAGGAGCACAAGGAGTACTTCTACACGAGGGAGCCGATGGCGCGCTTCTTGGACATGGGCGACATAAGCGAACAGGTGGCCTTAAAAGAACGCTTGAAGTGCAAAAGCTTCGGTTGGTTCATGGAAAACGTTGCGTACGATGTGTACGATAAGTTCCCGAAGCTCCCTAAGAACGTTCACTGGGGGATGGTGAAGAACAAAGCGACTGGTGCCTGCTTGGATACAATGGGGAAAGCCGCTCCGGCCTATATCGGTACGTCGTCGTGCCACGGGATGGGCAACAGCCAGTTGTTCAGGTTGAATGAGGCCGGCCAGCTCGGCGTCGGCGAGCGGTGCGTGGAGACCGACGGAGATAATGTTAAACAGGCCATTTGCAGACTCGGCACGGTTGACGGACCGTGGAGCTACAACGAGGAGCGCCATCAGCTGGTGCACCGGCTACACGGGCACTGCCTCACGCTGCAACCTCACTCCGGGCAGCTCGGCCTGGCGCCCTGCGACCCAAACAACACATACCAGCAGTGGACCGTCAAACAGAAAACGCCCAACTGACGAGCATCCATAACTAACCTTGACAAAGAGCTGATTCTCGATAAAGATCTGTTTCAAAACTTCACTGGGATGTCCAAAAGTGACTTCGAATATTTGTTGAATACAATTGGACCAAGAATCGAAAAAGGAGATACAAACATGAAAAAGGCAAGGGGAGGTGAGCGACGGAAAAGAGATGGACCTATACATCAGAGCAAAGACGATATACGGCAATATTGCAGTGAAGTCAAAGCGGGATAA

Protein

MSQKHANDVAETESKYGMNIAASNDIAMNRSIPDTRLDECKYWHYPEDLAKTSVIIVFHNEGFSVLMRTVHSVINRTPAQFLHEVVLVDDFSDKDDLKENLDNYIKRWNGKVRLVRNVQREGLIRTRSRGAQEATGDVIVFLDAHCEVNVNWLPPLLAPIYRDYRTMTVPVIDGIDYNTFEYRPVYQHGTNYRGIFEWGMLYKENEVPDREAHLHKHKSEPYKSPTHAGGLFAINRRYFLEIGAYDPGLLVWGGENFELSFKIWQCGGSIEWVPCSRVGHVYRAFMPYTFGNLAKNRKGSLITINYKRVIETWFDEEHKEYFYTREPMARFLDMGDISEQVALKERLKCKSFGWFMENVAYDVYDKFPKLPKNVHWGMVKNKATGACLDTMGKAAPAYIGTSSCHGMGNSQLFRLNEAGQLGVGERCVETDGDNVKQAICRLGTVDGPWSYNEERHQLVHRLHGHCLTLQPHSGQLGLAPCDPNNTYQQWTVKQKTPNXRASITNLDKELILDKDLFQNFTGMSKSDFEYLLNTIGPRIEKGDTNMKKARGGERRKRDGPIHQSKDDIRQYCSEVKAG

Cofactor

Mn(2+)

Similarity

Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.

Keywords

Complete proteome   Disulfide bond   Glycoprotein   Glycosyltransferase   Golgi apparatus   Lectin   Manganese   Membrane   Metal-binding   Reference proteome   Signal-anchor   Transferase   Transmembrane   Transmembrane helix  

Feature

chain  N-acetylgalactosaminyltransferase 7

Uniprot

L7WM53   H9JLX1   A0A2H1VQD2   A0A194PP64   A0A194QN11   A0A2A4JQI3   + More
A0A212EH41   A0A3S2NXY9   A0A1J1I0Y3   A0A1J1HZ59   A0A1Y1MRD7   A0A1B6CZF7   A0A1W4WX25   A0A1L8E219   A0A1L8E2H4   D2A249   A0A0L0C0P2   E2B8Q3   U5EM56   A0A0K8USE7   A0A0K8U016   A0A034VVC5   A0A0A1X9D8   T1PIY7   A0A0J7KZQ8   W8BIB6   K7ILV4   A0A154PQ83   E9IGN7   A0A2J7QQP9   Q17CM9   E2AX58   A0A1B6ITM6   A0A1B6H033   A0A1I8P174   B4NEM0   A0A182GZ72   A0A0M8ZUX5   A0A232FK05   A0A3B0KIV4   F4WQT7   A0A1Q3G303   Q29G11   A0A224XKM4   B4Q2Z3   A0A195EG02   A0A195ERQ7   B4I6T4   B4JJ43   B4MD68   A0A1W4UDI3   B3NTE9   X2JEA3   Q8MV48   A0A0N7ZAH1   A0A0P8Y0U8   A0A1B6ITI5   A0A0L7R4V4   B3MWP7   A0A151X3R5   A0A1A9WAR1   A0A195CZN3   A0A0M5J3I3   A0A195BQ00   A0A3L8DKW0   A0A336M2W9   A0A026W9A9   A0A1A9Y010   A0A067R3V9   A0A0C9QYV6   A0A182QEQ6   A0A1B0BYR3   A0A182LUG0   A0A182W5X1   A0A0A9WWW6   A0A182RKP6   A0A182J8H2   A0A1B0GAN4   A0A1A9VD82   A0A182US21   A0A1A9ZP58   A0A182UDT8   A0A182X7F3   Q7QEH0   A0A182I9Y7   A0A182N0U7   A0A088ANK9   A0A084WFL2   U4TWW9   A0A182S5T3   A0A182YH11   T1ID07   A0A182FJ66   A0A2A3EI05   A0A023F529   A0A2M3Z0S9   A0A2M4BHU2   A0A2M4BHW2   W5JDN9   A0A0M4ET62  

EC Number

2.4.1.-

Pubmed

19121390    26354079    22118469    28004739    18362917    19820115    + More
26108605    20798317    25348373    25830018    25315136    24495485    20075255    21282665    17510324    17994087    26483478    28648823    21719571    15632085    23185243    17550304    18057021    10731132    12537568    12537572    12537573    12537574    16110336    17569856    17569867    11925450    12829714    12537569    16251381    30249741    24508170    24845553    25401762    26823975    12364791    14747013    17210077    24438588    23537049    25244985    25474469    20920257    23761445   

EMBL

KC020486    AGC81884.1    BABH01005317    ODYU01003798    SOQ43007.1    KQ459603    + More
KPI92925.1    KQ461194    KPJ06908.1    NWSH01000775    PCG74297.1    AGBW02014975    OWR40790.1    RSAL01000028    RVE51863.1    CVRI01000037    CRK93244.1    CRK93243.1    GEZM01023703    JAV88221.1    GEDC01018635    JAS18663.1    GFDF01001311    JAV12773.1    GFDF01001312    JAV12772.1    KQ971338    EFA02739.1    JRES01001065    KNC25857.1    GL446361    EFN87959.1    GANO01001141    JAB58730.1    GDHF01022697    JAI29617.1    GDHF01032453    JAI19861.1    GAKP01012890    JAC46062.1    GBXI01012583    GBXI01006972    JAD01709.1    JAD07320.1    KA648644    AFP63273.1    LBMM01001595    KMQ96042.1    GAMC01009812    JAB96743.1    KQ435035    KZC14063.1    GL763054    EFZ20244.1    NEVH01012086    PNF30893.1    CH477307    EAT44068.1    GL443520    EFN62008.1    GECU01034289    GECU01017415    JAS73417.1    JAS90291.1    GECZ01001761    JAS68008.1    CH964239    EDW82189.1    JXUM01098952    JXUM01098953    JXUM01098954    KQ564458    KXJ72248.1    KQ435833    KOX71640.1    NNAY01000091    OXU31071.1    OUUW01000011    SPP86379.1    GL888275    EGI63450.1    GFDL01000884    JAV34161.1    CH379065    EAL31418.1    GFTR01007274    JAW09152.1    CM000162    EDX02727.1    KQ978983    KYN26824.1    KQ981993    KYN30908.1    CH480823    EDW56032.1    CH916370    EDV99595.1    CH940660    EDW58140.1    KRF78143.1    CH954180    EDV46600.1    AE014298    AHN59876.1    AF493067    AY268068    BT016123    AY058660    AY061339    GDRN01099126    JAI58832.1    CH902625    KPU75401.1    GECU01017461    JAS90245.1    KQ414657    KOC65806.1    EDV35032.1    KQ982562    KYQ54919.1    KQ977041    KYN06123.1    CP012528    ALC49998.1    KQ976424    KYM88597.1    QOIP01000007    RLU21011.1    UFQT01000116    SSX20328.1    KK107347    EZA52256.1    KK852777    KDR16767.1    GBYB01000899    GBYB01000900    JAG70666.1    JAG70667.1    AXCN02002175    JXJN01009832    JXJN01022772    AXCM01000747    GBHO01030657    GBRD01003603    GDHC01009836    JAG12947.1    JAG62218.1    JAQ08793.1    AXCP01008170    CCAG010022197    AAAB01008847    EAA06901.4    APCN01001075    ATLV01023372    KE525342    KFB49006.1    KB631581    ERL84483.1    ACPB03022137    KZ288254    PBC30806.1    GBBI01002554    JAC16158.1    GGFM01001369    MBW22120.1    GGFJ01003485    MBW52626.1    GGFJ01003486    MBW52627.1    ADMH02001465    ETN62482.1    CP012526    ALC48047.1   

Proteomes

UP000005204    UP000053268    UP000053240    UP000218220    UP000007151    UP000283053    + More
UP000183832    UP000192223    UP000007266    UP000037069    UP000008237    UP000095301    UP000036403    UP000002358    UP000076502    UP000235965    UP000008820    UP000000311    UP000095300    UP000007798    UP000069940    UP000249989    UP000053105    UP000215335    UP000268350    UP000007755    UP000001819    UP000002282    UP000078492    UP000078541    UP000001292    UP000001070    UP000008792    UP000192221    UP000008711    UP000000803    UP000007801    UP000053825    UP000075809    UP000091820    UP000078542    UP000092553    UP000078540    UP000279307    UP000053097    UP000092443    UP000027135    UP000075886    UP000092460    UP000075883    UP000075920    UP000075900    UP000075880    UP000092444    UP000078200    UP000075903    UP000092445    UP000075902    UP000076407    UP000007062    UP000075840    UP000075884    UP000005203    UP000030765    UP000030742    UP000075901    UP000076408    UP000015103    UP000069272    UP000242457    UP000000673   

PRIDE

L7WM53    H9JLX1    X2JEA3    Q8MV48   

Pfam

PF00535   Glycos_transf_2        + More
PF00652   Ricin_B_lectin
PF00324   AA_permease
PF03522   SLC12
PF00400   WD40

Interpro

IPR001173   Glyco_trans_2-like        + More
IPR029044   Nucleotide-diphossugar_trans       
IPR035992   Ricin_B-like_lectins       
IPR000772   Ricin_B_lectin       
IPR004841   AA-permease/SLC12A_dom       
IPR018491   SLC12_C       
IPR015943   WD40/YVTN_repeat-like_dom_sf       
IPR017986   WD40_repeat_dom       
IPR001680   WD40_repeat       
IPR020472   G-protein_beta_WD-40_rep       
IPR019775   WD40_repeat_CS       
IPR036322   WD40_repeat_dom_sf       

SUPFAM

SSF53448   SSF53448        + More
SSF50370   SSF50370       
SSF50978   SSF50978       

Gene 3D

3.90.550.10     2.130.10.10    

CDD

cd00161  RICIN

ProteinModelPortal

L7WM53   H9JLX1   A0A2H1VQD2   A0A194PP64   A0A194QN11   A0A2A4JQI3   + More
A0A212EH41   A0A3S2NXY9   A0A1J1I0Y3   A0A1J1HZ59   A0A1Y1MRD7   A0A1B6CZF7   A0A1W4WX25   A0A1L8E219   A0A1L8E2H4   D2A249   A0A0L0C0P2   E2B8Q3   U5EM56   A0A0K8USE7   A0A0K8U016   A0A034VVC5   A0A0A1X9D8   T1PIY7   A0A0J7KZQ8   W8BIB6   K7ILV4   A0A154PQ83   E9IGN7   A0A2J7QQP9   Q17CM9   E2AX58   A0A1B6ITM6   A0A1B6H033   A0A1I8P174   B4NEM0   A0A182GZ72   A0A0M8ZUX5   A0A232FK05   A0A3B0KIV4   F4WQT7   A0A1Q3G303   Q29G11   A0A224XKM4   B4Q2Z3   A0A195EG02   A0A195ERQ7   B4I6T4   B4JJ43   B4MD68   A0A1W4UDI3   B3NTE9   X2JEA3   Q8MV48   A0A0N7ZAH1   A0A0P8Y0U8   A0A1B6ITI5   A0A0L7R4V4   B3MWP7   A0A151X3R5   A0A1A9WAR1   A0A195CZN3   A0A0M5J3I3   A0A195BQ00   A0A3L8DKW0   A0A336M2W9   A0A026W9A9   A0A1A9Y010   A0A067R3V9   A0A0C9QYV6   A0A182QEQ6   A0A1B0BYR3   A0A182LUG0   A0A182W5X1   A0A0A9WWW6   A0A182RKP6   A0A182J8H2   A0A1B0GAN4   A0A1A9VD82   A0A182US21   A0A1A9ZP58   A0A182UDT8   A0A182X7F3   Q7QEH0   A0A182I9Y7   A0A182N0U7   A0A088ANK9   A0A084WFL2   U4TWW9   A0A182S5T3   A0A182YH11   T1ID07   A0A182FJ66   A0A2A3EI05   A0A023F529   A0A2M3Z0S9   A0A2M4BHU2   A0A2M4BHW2   W5JDN9   A0A0M4ET62  

PDB

6IWR     E-value=2.25635e-134,     Score=1228

KEGG

101735613    K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] | (RefSeq) GalNAc-T; N-acetylgala

PATHWAY

00512    Mucin type O-glycan biosynthesis - Bombyx mori (domestic silkworm)
01100    Metabolic pathways - Bombyx mori (domestic silkworm)

GO

GO:0016757   GO:0030246   GO:0006486   GO:0016021   GO:0000139   GO:0006811   GO:0005794   GO:0005215   GO:0055085   GO:0004653   GO:0009312   GO:0046872   GO:0012505   GO:0005795  

Subcellular location

Golgi apparatus membrane  

Length:

578

Number of predicted TMHs:

0

Exp number of AAs in TMHs:

0.01431

Exp number, first 60 AAs:

0.00495

Total prob of N-in:

0.00350

outside

1  -  578

 

 

Pi

164.552303

Theta

187.989894

Tajima's D

-0.519777

CLR

0.542996

CSRT

0.233438328083596

Interpretation

Uncertain